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公开(公告)号：US09259587B2
公开(公告)日：2016-02-16
申请号：US13152870
申请日：2011-06-03
申请人： Steven M. Goetz , Andrew H. Houchins , Jeffrey T. Keacher , Gary W. King , Kenneth T. Heruth , Roy L. Testerman , Michael T. Lee , Nathan A. Torgerson , Joseph J. Nolan
发明人： Steven M. Goetz , Andrew H. Houchins , Jeffrey T. Keacher , Gary W. King , Kenneth T. Heruth , Roy L. Testerman , Michael T. Lee , Nathan A. Torgerson , Joseph J. Nolan
CPC分类号： A61N1/37247 , A61N1/36071 , A61N1/36185 , A61N1/37252
摘要： The disclosure is directed to techniques for shifting between two electrode combinations. An amplitude of a first electrode combination is incrementally decreased while an amplitude of a second, or subsequent, electrode combination is concurrently incrementally increased. Alternatively, an amplitude of the first electrode combination is maintained at a target amplitude level while the amplitude of the second electrode combination is incrementally increased. The stimulation pulses of the electrode combinations are delivered to the patient interleaved in time. In this manner, the invention provides for a smooth, gradual shift from a first electrode combination to a second electrode combination, allowing the patient to maintain a continual perception of stimulation. The shifting techniques described herein may be used during programming to shift between different electrode combinations to find an efficacious electrode combination. Additionally, the techniques may be used for shifting between different electrode combinations associated with different stimulation programs or program sets.
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2.发明授权公开(公告)号：US08751007B2
公开(公告)日：2014-06-10
申请号：US13251911
申请日：2011-10-03
申请人： Steven M. Goetz , Andrew H. Houchins , Jeffrey T. Keacher , Gary W. King , Kenneth T. Heruth , Roy L. Testerman , Michael T. Lee , Nathan A. Torgerson , Joseph J. Nolan
发明人： Steven M. Goetz , Andrew H. Houchins , Jeffrey T. Keacher , Gary W. King , Kenneth T. Heruth , Roy L. Testerman , Michael T. Lee , Nathan A. Torgerson , Joseph J. Nolan
CPC分类号： A61N1/37247 , A61N1/36071 , A61N1/36185 , A61N1/37252
摘要： The disclosure is directed to techniques for shifting between two electrode combinations. An amplitude of a first electrode combination is incrementally decreased while an amplitude of a second, or subsequent, electrode combination is concurrently incrementally increased. Alternatively, an amplitude of the first electrode combination is maintained at a target amplitude level while the amplitude of the second electrode combination is incrementally increased. The stimulation pulses of the electrode combinations are delivered to the patient interleaved in time. In this manner, the invention provides for a smooth, gradual shift from a first electrode combination to a second electrode combination, allowing the patient to maintain a continual perception of stimulation. The shifting techniques described herein may be used during programming to shift between different electrode combinations to find an efficacious electrode combination. Additionally, the techniques may be used for shifting between different electrode combinations associated with different stimulation programs or program sets.
摘要翻译： 本公开涉及用于在两个电极组合之间移位的技术。 第一电极组合的振幅逐渐减小，而第二或随后的电极组合的振幅同时递增地增加。 或者，第一电极组合的振幅保持在目标振幅水平，而第二电极组合的振幅逐渐增加。 电极组合的刺激脉冲在时间上交付给患者。 以这种方式，本发明提供从第一电极组合到第二电极组合的平滑，逐渐的移动，允许患者保持连续的刺激感知。 本文描述的移位技术可以在编程期间用于在不同电极组合之间移动以找到有效的电极组合。 另外，这些技术可用于在与不同刺激程序或程序集相关联的不同电极组合之间进行移位。
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公开(公告)号：US20120078325A1
公开(公告)日：2012-03-29
申请号：US13310136
申请日：2011-12-02
IPC分类号： A61N1/372
CPC分类号： A61N1/37247 , A61N1/36082 , A61N1/36185 , Y10S128/903
摘要： A programmer allows a clinician to identify combinations of electrodes from within an electrode set implanted in a patient that enable delivery of desirable neurostimulation therapy by an implantable medical device. The programmer executes an electrode combination search algorithm to select combinations of electrodes to test in a non-random order. According to algorithms consistent with the invention, the programmer may first identify a position of a first cathode for subsequent combinations, and then select electrodes from the set to test with the first cathode as anodes or additional cathodes based on the proximity of the electrodes to the first cathode. The programmer may store information for each combination tested, and the information may facilitate the identification of desirable electrode combinations by the clinician. The clinician may create neurostimulation therapy programs that include identified desirable program combinations.
摘要翻译： 程序员允许临床医生从植入在患者体内的电极组中识别电极的组合，其能够通过可植入医疗装置递送所需的神经刺激疗法。 编程器执行电极组合搜索算法以选择电极的组合以非随机顺序进行测试。 根据与本发明一致的算法，程序员可以首先识别用于后续组合的第一阴极的位置，然后基于电极与电极的接近度，从第一阴极中选择电极作为阳极或附加阴极进行测试 第一阴极。 程序员可以存储每个测试组合的信息，并且该信息可以有助于由临床医生识别期望的电极组合。 临床医生可以创建神经刺激治疗程序，其包括所识别的期望程序组合。
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公开(公告)号：US07623919B2
公开(公告)日：2009-11-24
申请号：US11414536
申请日：2006-04-28
IPC分类号： A61N1/05
CPC分类号： A61N1/37 , A61N1/36114 , A61N1/3706 , A61N2001/083
摘要： Techniques for performing lead functionality tests, e.g., lead impedance tests, for implantable electrical leads are described. In some of the described embodiments, an implantable medical device determines whether a patient is in a target activity state, e.g., an activity state in which lead impedance testing will be unobtrusive, such as when a patient is asleep, or capture information of particular interest, such as when the patient is active, in a particular posture, or changing postures. The implantable medical device performs the lead functionality test based on this determination. Additionally, in some embodiments, the implantable medical device may group a plurality of measurements for a single lead functionality test into a plurality of sessions, and perform the measurement sessions interleaved with delivery of therapeutic stimulation.
摘要翻译： 描述了用于执行用于可植入电引线的引线功能测试（例如引线阻抗测试）的技术。 在一些所描述的实施例中，可植入医疗设备确定患者是否处于目标活动状态，例如，其中导线阻抗测试将是不显眼的活动状态，例如当患者睡着时或捕获特定感兴趣的信息 ，例如当患者活跃时，处于特定姿势，或改变姿势。 可植入医疗装置基于该确定执行引导功能测试。 另外，在一些实施例中，可植入医疗装置可以将用于单个引线功能测试的多个测量分组成多个会话，并且执行与递送治疗性刺激交错的测量会话。
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公开(公告)号：US20120022615A1
公开(公告)日：2012-01-26
申请号：US13251925
申请日：2011-10-03
申请人： Steven M. Goetz , Andrew H. Houchins , Jeffrey T. Keacher , Gary W. King , Kenneth T. Heruth , Roy L. Testerman , Michael T. Lee , Nathan A. Torgerson , Joseph J. Nolan
发明人： Steven M. Goetz , Andrew H. Houchins , Jeffrey T. Keacher , Gary W. King , Kenneth T. Heruth , Roy L. Testerman , Michael T. Lee , Nathan A. Torgerson , Joseph J. Nolan
IPC分类号： A61N1/378
CPC分类号： A61N1/37247 , A61N1/36071 , A61N1/36185 , A61N1/37252
摘要： The disclosure is directed to techniques for shifting between two electrode combinations. An amplitude of a first electrode combination is incrementally decreased while an amplitude of a second, or subsequent, electrode combination is concurrently incrementally increased. Alternatively, an amplitude of the first electrode combination is maintained at a target amplitude level while the amplitude of the second electrode combination is incrementally increased. The stimulation pulses of the electrode combinations are delivered to the patient interleaved in time. In this manner, the invention provides for a smooth, gradual shift from a first electrode combination to a second electrode combination, allowing the patient to maintain a continual perception of stimulation. The shifting techniques described herein may be used during programming to shift between different electrode combinations to find an efficacious electrode combination. Additionally, the techniques may be used for shifting between different electrode combinations associated with different stimulation programs or program sets.
摘要翻译： 本公开涉及用于在两个电极组合之间移位的技术。 第一电极组合的振幅逐渐减小，而第二或随后的电极组合的振幅同时递增地增加。 或者，第一电极组合的振幅保持在目标振幅水平，而第二电极组合的振幅逐渐增加。 电极组合的刺激脉冲在时间上交付给患者。 以这种方式，本发明提供从第一电极组合到第二电极组合的平滑，逐渐的移动，允许患者保持连续的刺激感知。 本文描述的移位技术可以在编程期间用于在不同电极组合之间移动以找到有效的电极组合。 另外，这些技术可用于在与不同刺激程序或程序集相关联的不同电极组合之间进行移位。
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公开(公告)号：US20120022614A1
公开(公告)日：2012-01-26
申请号：US13251911
申请日：2011-10-03
申请人： Steven M. Goetz , Andrew H. Houchins , Jeffrey T. Keacher , Gary W. King , Kenneth T. Heruth , Roy L. Testerman , Michael T. Lee , Nathan A. Torgerson , Joseph J. Nolan
发明人： Steven M. Goetz , Andrew H. Houchins , Jeffrey T. Keacher , Gary W. King , Kenneth T. Heruth , Roy L. Testerman , Michael T. Lee , Nathan A. Torgerson , Joseph J. Nolan
IPC分类号： A61N1/372
CPC分类号： A61N1/37247 , A61N1/36071 , A61N1/36185 , A61N1/37252
摘要： The disclosure is directed to techniques for shifting between two electrode combinations. An amplitude of a first electrode combination is incrementally decreased while an amplitude of a second, or subsequent, electrode combination is concurrently incrementally increased. Alternatively, an amplitude of the first electrode combination is maintained at a target amplitude level while the amplitude of the second electrode combination is incrementally increased. The stimulation pulses of the electrode combinations are delivered to the patient interleaved in time. In this manner, the invention provides for a smooth, gradual shift from a first electrode combination to a second electrode combination, allowing the patient to maintain a continual perception of stimulation. The shifting techniques described herein may be used during programming to shift between different electrode combinations to find an efficacious electrode combination. Additionally, the techniques may be used for shifting between different electrode combinations associated with different stimulation programs or program sets.
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7.发明授权公开(公告)号：US07519431B2
公开(公告)日：2009-04-14
申请号：US11401100
申请日：2006-04-10
申请人： Steven M. Goetz , Andrew H. Houchins , Jeffrey T. Keacher , Gary W. King , Kenneth T. Heruth , Roy L. Testerman , Michael T. Lee , Nathan A. Torgerson , Joseph J. Nolan
发明人： Steven M. Goetz , Andrew H. Houchins , Jeffrey T. Keacher , Gary W. King , Kenneth T. Heruth , Roy L. Testerman , Michael T. Lee , Nathan A. Torgerson , Joseph J. Nolan
IPC分类号： A61N1/18
CPC分类号： A61N1/37247 , A61N1/36071 , A61N1/36185 , A61N1/37252
摘要： The disclosure is directed to techniques for shifting between two electrode combinations. An amplitude of a first electrode combination is incrementally decreased while an amplitude of a second, or subsequent, electrode combination is concurrently incrementally increased. Alternatively, an amplitude of the first electrode combination is maintained at a target amplitude level while the amplitude of the second electrode combination is incrementally increased. The stimulation pulses of the electrode combinations are delivered to the patient interleaved in time. In this manner, the invention provides for a smooth, gradual shift from a first electrode combination to a second electrode combination, allowing the patient to maintain a continual perception of stimulation. The shifting techniques described herein may be used during programming to shift between different electrode combinations to find an efficacious electrode combination. Additionally, the techniques may be used for shifting between different electrode combinations associated with different stimulation programs or program sets.
摘要翻译： 本公开涉及用于在两个电极组合之间移位的技术。 第一电极组合的振幅逐渐减小，而第二或随后的电极组合的振幅同时递增地增加。 或者，第一电极组合的振幅保持在目标振幅水平，而第二电极组合的振幅逐渐增加。 电极组合的刺激脉冲在时间上交付给患者。 以这种方式，本发明提供从第一电极组合到第二电极组合的平滑，逐渐的移动，允许患者保持连续的刺激感知。 本文描述的移位技术可以在编程期间用于在不同电极组合之间移动以找到有效的电极组合。 另外，这些技术可用于在与不同刺激程序或程序集相关联的不同电极组合之间进行移位。
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公开(公告)号：US08649872B2
公开(公告)日：2014-02-11
申请号：US13310136
申请日：2011-12-02
IPC分类号： A61N1/00
CPC分类号： A61N1/37247 , A61N1/36082 , A61N1/36185 , Y10S128/903
摘要： A programmer allows a clinician to identify combinations of electrodes from within an electrode set implanted in a patient that enable delivery of desirable neurostimulation therapy by an implantable medical device. The programmer executes an electrode combination search algorithm to select combinations of electrodes to test in a non-random order. According to algorithms consistent with the invention, the programmer may first identify a position of a first cathode for subsequent combinations, and then select electrodes from the set to test with the first cathode as anodes or additional cathodes based on the proximity of the electrodes to the first cathode. The programmer may store information for each combination tested, and the information may facilitate the identification of desirable electrode combinations by the clinician. The clinician may create neurostimulation therapy programs that include identified desirable program combinations.
摘要翻译： 程序员允许临床医生从植入在患者体内的电极组中识别电极的组合，其能够通过可植入医疗装置递送所需的神经刺激疗法。 编程器执行电极组合搜索算法以选择电极的组合以非随机顺序进行测试。 根据与本发明一致的算法，程序员可以首先识别用于后续组合的第一阴极的位置，然后基于电极与电极的接近度，从第一阴极中选择电极作为阳极或附加阴极进行测试 第一阴极。 程序员可以存储每个测试组合的信息，并且该信息可以有助于由临床医生识别期望的电极组合。 临床医生可以创建神经刺激治疗程序，其包括所识别的期望程序组合。
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公开(公告)号：US08068915B2
公开(公告)日：2011-11-29
申请号：US11698655
申请日：2007-01-26
IPC分类号： A61N1/00
CPC分类号： A61N1/37247 , A61N1/36082 , A61N1/36185 , Y10S128/903
摘要： A programmer allows a clinician to identify desirable combinations of electrodes from within an electrode set implanted in a patient that enable delivery of desirable neurostimulation therapy by an implantable medical device. The clinician may create neurostimulation therapy programs that include identified desirable electrode combinations. In some embodiments, the clinician may use the programmer to select a program, such as a program identified during a neurostimulation programming session, and direct the programmer to replicate the selected program. The programmer may change one or more parameters of the selected program, such as pulse amplitude or duty cycle, when generating the copy of the selected program. In some embodiments, the programmer may associate each of a plurality of programs identified during a neurostimulation therapy programming session with one or more program categories, and may automatically generate program groups that include two or more of the programs based on the program categories.
摘要翻译： 程序员允许临床医生从植入患者体内的电极组中识别电极的期望组合，从而能够通过可植入医疗装置递送所需的神经刺激疗法。 临床医生可以产生神经刺激治疗程序，其包括所识别的期望的电极组合。 在一些实施例中，临床医生可以使用编程器来选择程序，诸如在神经刺激编程会话期间识别的程序，并指示程序员复制所选择的程序。 当生成所选程序的副本时，编程器可以改变所选程序的一个或多个参数，例如脉冲幅度或占空比。 在一些实施例中，程序员可以将在神经刺激治疗程序设计会话期间识别的多个程序中的每一个与一个或多个程序类别相关联，并且可以基于程序类别自动生成包括两个或更多程序的程序组。
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10.发明授权公开(公告)号：US07974703B2
公开(公告)日：2011-07-05
申请号：US12406607
申请日：2009-03-18
申请人： Steven M. Goetz , Andrew H. Houchins , Jeffrey T. Keacher , Gary W. King , Kenneth T. Heruth , Roy L. Testerman , Michael T. Lee , Nathan A. Torgerson , Joseph J. Nolan
发明人： Steven M. Goetz , Andrew H. Houchins , Jeffrey T. Keacher , Gary W. King , Kenneth T. Heruth , Roy L. Testerman , Michael T. Lee , Nathan A. Torgerson , Joseph J. Nolan
IPC分类号： A61N1/18
CPC分类号： A61N1/37247 , A61N1/36071 , A61N1/36185 , A61N1/37252
摘要： Techniques for shifting between two electrode combinations. An amplitude of a first electrode combination is incrementally decreased while an amplitude of a second, or subsequent, electrode combination is concurrently incrementally increased. Alternatively, an amplitude of the first electrode combination is maintained at a target amplitude level while the amplitude of the second electrode combination is incrementally increased. The stimulation pulses of the electrode combinations are delivered to the patient interleaved in time. In this manner, the invention provides for a smooth, gradual shift from a first electrode combination to a second electrode combination, allowing the patient to maintain a continual perception of stimulation. The shifting techniques described herein may be used during programming to shift between different electrode combinations to find an efficacious electrode combination. Additionally, the techniques may be used for shifting between different electrode combinations associated with different stimulation programs or program sets.
摘要翻译： 用于在两个电极组合之间切换的技术。 第一电极组合的振幅逐渐减小，而第二或随后的电极组合的振幅同时递增地增加。 或者，第一电极组合的振幅保持在目标振幅水平，而第二电极组合的振幅逐渐增加。 电极组合的刺激脉冲在时间上交付给患者。 以这种方式，本发明提供从第一电极组合到第二电极组合的平滑，逐渐的移动，允许患者保持连续的刺激感知。 本文描述的移位技术可以在编程期间用于在不同电极组合之间移动以找到有效的电极组合。 另外，这些技术可用于在与不同刺激程序或程序集相关联的不同电极组合之间进行移位。
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