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15 条记录 (耗时 0.059 秒)

    Fibronectin binding protein B compounds
    8.
    发明授权
    Fibronectin binding protein B compounds 失效

    公开(公告)号：US5858709A

    公开(公告)日：1999-01-12

    申请号：US732791

    申请日：1996-10-15

    申请人： John Edward Hodgson ,  Martin Karl Russell Burnham

    发明人： John Edward Hodgson ,  Martin Karl Russell Burnham

    IPC分类号： A61K38/00 ,  A61K39/00 ,  C07K14/31 ,  C12P21/06 ,  C07H21/02 ,  C07H21/04

    CPC分类号： C07K14/31 ,  A61K38/00 ,  A61K39/00 ,  C07K2319/00

    摘要： Novel fibronectin binding protein B polypeptides and DNA (RNA) encoding such novel fibronectin binding protein B and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such novel fibronectin binding protein B for the treatment of infection, particularly bacterial infections. Antagonists against such novel fibronectin binding protein B and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of novel fibronectin binding protein B nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding novel fibronectin binding protein B family and for detecting the polypeptide in a host.

    Fibronectin binding protein B compounds
    9.
    发明授权
    Fibronectin binding protein B compounds 失效
    纤连蛋白结合蛋白B化合物

    公开(公告)号：US6077677A

    公开(公告)日：2000-06-20

    申请号：US205049

    申请日：1998-12-04

    申请人： John Edward Hodgson ,  Martin Karl Russell Burnham

    发明人： John Edward Hodgson ,  Martin Karl Russell Burnham

    IPC分类号： A61K38/00 ,  A61K39/00 ,  C07K14/31 ,  G01N33/53

    CPC分类号： C07K14/31 ,  A61K38/00 ,  A61K39/00 ,  C07K2319/00

    摘要： Novel fibronectin binding protein B polypeptides and DNA (RNA) encoding such novel fibronectin binding protein B and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such novel fibronectin binding protein B for the treatment of infection, particularly bacterial infections. Antagonists against such novel fibronectin binding protein B and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of novel fibronectin binding protein B nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding novel fibronectin binding protein B family and for detecting the polypeptide in a host.

    摘要翻译： 公开了新型纤连蛋白结合蛋白B多肽和编码这种新型纤连蛋白结合蛋白B的DNA（RNA）和通过重组技术产生此类多肽的方法。 还公开了利用这种新型纤连蛋白结合蛋白B来治疗感染，特别是细菌感染的方法。 还公开了抗这种新型纤连蛋白结合蛋白B的拮抗剂及其用作治疗感染特别是细菌感染的治疗剂。 还公开了用于检测与宿主中新型纤连蛋白结合蛋白B核酸序列和多肽的存在相关的疾病的诊断测定。 还公开了用于检测编码新型纤连蛋白结合蛋白B家族的多核苷酸并用于检测宿主中的多肽的诊断测定。

    Polynucleotide encoding saliva binding protein
    10.
    发明授权
    Polynucleotide encoding saliva binding protein 失效
    多核苷酸编码唾液结合蛋白

    公开(公告)号：US5801234A

    公开(公告)日：1998-09-01

    申请号：US896371

    申请日：1997-07-18

    申请人： John Edward Hodgson ,  Martin Karl Russell Burnham

    发明人： John Edward Hodgson ,  Martin Karl Russell Burnham

    IPC分类号： G01N33/50 ,  A61K31/00 ,  A61K38/00 ,  A61K39/00 ,  A61K39/395 ,  A61K45/00 ,  A61K48/00 ,  A61P31/00 ,  A61P31/04 ,  C07K14/31 ,  C07K16/12 ,  C12N1/21 ,  C12N15/09 ,  C12N15/31 ,  C12P21/08 ,  C12Q1/68 ,  G01N33/15 ,  G01N33/53 ,  C07H21/04

    CPC分类号： C07K14/31 ,  A61K39/00 ,  A61K48/00

    摘要： Saliva binding protein polypeptides and DNA (RNA) of Staphylococcus aureus encoding such saliva binding protein and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such saliva binding protein for the treatment of infection, particularly bacterial infections. Antagonists against such saliva binding protein and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of saliva binding protein nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding saliva binding protein family and for detecting the polypeptide in host.

    摘要翻译： 公开了唾液结合蛋白多肽和编码这种唾液结合蛋白的金黄色葡萄球菌的DNA（RNA）和通过重组技术产生这种多肽的方法。 还公开了利用这种唾液结合蛋白来治疗感染，特别是细菌感染的方法。 还公开了抗这种唾液结合蛋白的拮抗剂及其用作治疗感染，特别是细菌感染的治疗剂。 还公开了用于检测与宿主中唾液结合蛋白核酸序列和多肽的存在相关的疾病的诊断测定法。 还公开了用于检测编码唾液结合蛋白家族的多核苷酸并用于检测宿主中的多肽的诊断测定。