公开(公告)号：US12138362B2

公开(公告)日：2024-11-12

申请号：US18510358

申请日：2023-11-15

Applicant: MicroVention, Inc.

Inventor： Gregory M. Cruise ,  Steve Plotkin ,  Xinping Wu

IPC: A61L24/06 ,  A61L24/00 ,  C08F222/38

Abstract: Embolic particles are described. The particles are reaction products of a prepolymer solution including at least one polyether macromer and an appropriate monomer.

公开(公告)号：US20240336552A1

公开(公告)日：2024-10-10

申请号：US18294911

申请日：2022-08-02

Applicant: MicroVention, Inc.

Inventor： Gloria Hincapie ,  Petr Vasek ,  Gregory M. Cruise

IPC: C07C69/65 ,  A61K51/04 ,  C07C69/63

CPC classification number: C07C69/65 ,  A61K51/0402 ,  C07C69/63

Abstract: Described are improved processes for the preparation of iodized fatty acid esters from free fatty acids via in-situ formation of hydroiodic acid using silane chemistry.

公开(公告)号：US20240108781A1

公开(公告)日：2024-04-04

申请号：US18482688

申请日：2023-10-06

Applicant: MicroVention, Inc.

Inventor： Gregory M. Cruise ,  Michael J. Constant ,  Edward Michael Keeley ,  Rob Greene ,  Clayton Harris

IPC: A61L24/06 ,  A61K49/04 ,  A61K49/12 ,  A61L24/00

CPC classification number: A61L24/06 ,  A61K49/0442 ,  A61K49/12 ,  A61L24/001 ,  A61L24/0015 ,  A61L2300/44 ,  A61L2400/06 ,  A61L2430/36

Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological solution; wherein the biocompatible polymer is soluble in the non-physiological solution and insoluble in a physiological solution. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.

公开(公告)号：US20230303743A1

公开(公告)日：2023-09-28

申请号：US18023296

申请日：2021-08-31

Applicant: MicroVention, Inc.

Inventor： Gregory M. Cruise ,  Xinping Wu

IPC: C08F220/28 ,  C08L33/14 ,  A61L33/06

CPC classification number: C08F220/285 ,  C08F220/281 ,  C08L33/14 ,  A61L33/064 ,  A61L2420/02

Abstract: Described herein are polymeric coatings, methods of preparing the polymeric coatings, methods of using the polymeric coatings, and substrates including one or more surfaces coated with the polymeric coatings.

公开(公告)号：US20220162470A1

公开(公告)日：2022-05-26

申请号：US17534886

申请日：2021-11-24

Applicant: MicroVention, Inc.

Inventor： Xinping Wu ,  Petr Vasek ,  Steve Plotkin ,  Gregory M. Cruise

IPC: C09D133/06 ,  C09D133/14 ,  C08J7/04 ,  C08F220/28 ,  B05D7/02 ,  B05D7/00

Abstract: Described herein are surface-treated polymeric substrates. Also described herein are polymeric coatings, which may be used as surface treatments.

公开(公告)号：US11331340B2

公开(公告)日：2022-05-17

申请号：US16806936

申请日：2020-03-02

Applicant: MicroVention, Inc.

Inventor： Gregory M. Cruise ,  Michael J. Constant ,  Joshua Garretson

IPC: A61K31/785 ,  A61K9/00 ,  A61K31/78 ,  A61L24/00 ,  A61L24/04 ,  A61K47/32

Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.

公开(公告)号：US20210290816A1

公开(公告)日：2021-09-23

申请号：US17204581

申请日：2021-03-17

Applicant: MicroVention, Inc.

Inventor： Matthew Fitz ,  Gregory M. Cruise ,  Makoto Harumoto ,  Yue Wu

IPC: A61L24/00 ,  A61K31/337 ,  A61K31/4745 ,  A61K31/351 ,  A61K31/404 ,  A61K31/44 ,  A61K31/7068 ,  A61K31/282 ,  A61K31/664 ,  A61K31/4188 ,  A61K31/17 ,  A61K51/06 ,  A61L24/04

Abstract: Described herein are formulations that transition from a liquid state to a solid state for use in the embolization of arteriovenous malformations (AVM's) and solid tumors.

公开(公告)号：US10383973B2

公开(公告)日：2019-08-20

申请号：US16184862

申请日：2018-11-08

Applicant: MIcroVention, Inc.

Inventor： Gregory M. Cruise ,  Steve Plotkin ,  Xinping Wu

IPC: C08F220/38 ,  C08F220/56 ,  C08F222/10 ,  C08F222/38 ,  C08F222/40 ,  A61K9/00 ,  A61K9/16 ,  A61L24/06 ,  A61L24/00

Abstract: Embolic particles are described. The particles are reaction products of a prepolymer solution including at least one polyether macromer and an appropriate monomer.

公开(公告)号：US10258716B2

公开(公告)日：2019-04-16

申请号：US15491864

申请日：2017-04-19

Applicant: MicroVention, Inc.

Inventor： Gregory M. Cruise ,  Michael J. Constant ,  Edward Michael Keeley ,  Rob Greene ,  Clayton Harris

IPC: A61K49/04 ,  A61K49/12 ,  A61L24/04 ,  A61L24/06 ,  A61L24/00

Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological pH solution; wherein the biocompatible polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.

公开(公告)号：US20190076571A1

公开(公告)日：2019-03-14

申请号：US16184862

申请日：2018-11-08

Applicant: MIcroVention, Inc.

Inventor： Gregory M. Cruise ,  Steve Plotkin ,  Xinping Wu

IPC: A61L24/06 ,  C08F222/38 ,  A61L24/00 ,  C08L33/08 ,  C08L33/10 ,  C08L33/26

CPC classification number: A61L24/06 ,  A61L24/001 ,  A61L2430/36 ,  C08F222/385 ,  C08L33/08 ,  C08L33/10 ,  C08L33/26

Abstract: Embolic particles are described. The particles are reaction products of a prepolymer solution including at least one polyether macromer and an appropriate monomer.