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公开(公告)号:US06583138B1
公开(公告)日:2003-06-24
申请号:US09622458
申请日:2001-01-04
申请人: Mitsuaki Miyamoto , Tatsuya Yoshiuchi , Keizo Sato , Motohiro Soejima , Takashi Sato , Koichi Kikuchi , Hiroyuki Yoshimura , Katsuhiro Moriya , Yoshinori Sakuma , Shigeru Akasofu , Koji Yamada
发明人: Mitsuaki Miyamoto , Tatsuya Yoshiuchi , Keizo Sato , Motohiro Soejima , Takashi Sato , Koichi Kikuchi , Hiroyuki Yoshimura , Katsuhiro Moriya , Yoshinori Sakuma , Shigeru Akasofu , Koji Yamada
IPC分类号: C07D51304
CPC分类号: C07D513/04
摘要: The invention provides a novel heterocyclic ring condensed benzothiazine compound which is effective for prevention or remedy of disease, in which histamine, leukotriene and the like participate. The heterocyclic ring condensed benzothiazine compound of the present invention or a pharmacologically acceptable salt thereof is effective for prevention or remedy of disease, in which a chemical mediator, such as histamine, leukotriene and the like, participate, for example, asthma, allergic coryza, atopic dermatitis, hives, hay fever, gastrointestinal allergy, food allergy and the like. Further, the heterocyclic ring condensed benzothiazine compound of the present invention, its pharmacologically acceptable salt or hydrates thereof is represented by the following formula: In the formula, the ring Het represents an unsaturated heterocyclic ring; R1 and R2 are the same as or different from each other, and each represents halogen atom, a lower alkyl group that may be substituted with a halogen atom, a lower alkoxy group that may be substituted with a halogen atom, a lower alkyl lower alkoxy group, cyano group; D represents a lower alkylene group and the like that may have a substituent; Q represents, for example, the formula —NR20R2 (in the formula, R20 and R21 are the same as or different from each other, and each represents hydrogen atom, a lower alkyl group that may be substituted with a halogen atom, an aryl group that may have a substituent, an arylalkyl group that may have a substituent, a heteroaryl group that may have a substituent or a heteroarylalkyl group that may have a substituent, or R20 and R21 may form a 3- to 8-membered ring along with the nitrogen atom to which they are bound); and x represents an integer of from 1 to 2.
摘要翻译: 本发明提供一种新颖的杂环稠合苯并噻嗪化合物,其对组胺,白细胞三烯等参与的疾病的预防或治疗有效。 本发明的杂环稠合苯并噻嗪化合物或其药理学上可接受的盐对于预防或治疗其中化学介质如组胺,白三烯等参与的疾病是有效的,例如哮喘,过敏性鼻炎, 特应性皮炎,荨麻疹,花粉症,胃肠道过敏,食物过敏等。 此外,本发明的杂环稠合苯并噻嗪化合物,其药理学上可接受的盐或其水合物由下式表示:式中,环Het表示不饱和杂环; R1和R2彼此相同或不同,各自表示卤素原子,可以被卤素原子取代的低级烷基,可被卤素原子取代的低级烷氧基,低级烷基低级烷氧基 基团,氰基; D表示可以具有取代基的低级亚烷基等; Q表示例如式-NR20R2(式中,R20和R21彼此相同或不同,各自表示氢原子,可被卤素原子取代的低级烷基,芳基 可以具有取代基的芳基烷基,可以具有取代基的芳基烷基,可以具有取代基的杂芳基或可以具有取代基的杂芳基烷基,或者R20和R21可以与 氮原子); x表示1〜2的整数。
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公开(公告)号:US6121309A
公开(公告)日:2000-09-19
申请号:US125522
申请日:1998-08-20
申请人: Katsuya Tagami , Hiroyuki Yoshimura , Mitsuo Nagai , Shigeki Hibi , Kouichi Kikuchi , Takashi Sato , Makoto Okita , Yasushi Okamoto , Yumiko Nagasaka , Naoki Kobayashi , Takayuki Hida , Kenji Tai , Naoki Tokuhara , Seiichi Kobayashi
发明人: Katsuya Tagami , Hiroyuki Yoshimura , Mitsuo Nagai , Shigeki Hibi , Kouichi Kikuchi , Takashi Sato , Makoto Okita , Yasushi Okamoto , Yumiko Nagasaka , Naoki Kobayashi , Takayuki Hida , Kenji Tai , Naoki Tokuhara , Seiichi Kobayashi
IPC分类号: C07C69/76 , C07C69/94 , C07D207/32 , C07D207/337 , C07D307/54 , C07D333/24 , C07D405/04 , C07D405/10 , C07D405/14 , C07D407/04 , C07D409/04 , C07D409/10 , C07D409/14 , A61K31/40 , C07D405/00
CPC分类号: C07D207/337 , C07C69/76 , C07C69/94 , C07D307/54 , C07D333/24 , C07D405/04 , C07D405/10 , C07D405/14 , C07D407/04 , C07D409/04 , C07D409/10 , C07D409/14
摘要: The present invention provides a medicament exhibiting excellent retinoic acid receptor agonism.A Carboxylic acid derivative having a fused ring which is represented by the following formula or a pharmacologically acceptable salt thereof: ##STR1## {wherein the symbol ----- represents a single bond or a double bond; X, Y, Z, P, Q, U, V and W are each a group represented by the formula: --O-- or --S--, or a group represented by the formula: ##STR2## [wherein R.sup.k (k:1 to 8) is hydrogen, halogeno, optionally substituted lower alkyl or the like, with either of R.sup.7 and R.sup.8 being a group represented by the formula: ##STR3## (wherein A and B are each independently an optionally substituted aromatic hydrocarbon ring or an optionally substituted unsaturated heterocycle; and D is optionally protected carboxyl)]}.
摘要翻译: PCT No.PCT / JP97 / 00852 Sec。 371日期:1998年8月20日 102(e)1998年8月20日PCT PCT 1997年3月18日PCT公布。 公开号WO97 / 34869 日期:1997年9月25日本发明提供了显示出优异的视黄酸受体激动作用的药物。 具有由下式表示的稠环的羧酸衍生物或其药理学上可接受的盐:{其中符号+ E,uns ----- + EE表示单键或双键; X,Y,Z,P,Q,U,V和W分别是由下式表示的基团:-O-或-S-,或由下式表示的基团:[其中R k(k:1至8) 是氢,卤素,任选取代的低级烷基等,其中R 7和R 8中的任一个是由下式表示的基团:(其中A和B各自独立地是任选取代的芳族烃环或任选取代的不饱和杂环; D 任选保护羧基)]}。
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公开(公告)号:US6110959A
公开(公告)日:2000-08-29
申请号:US400980
申请日:1999-09-22
申请人: Katsuya Tagami , Hiroyuki Yoshimura , Mitsuo Nagai , Shigeki Hibi , Kouichi Kikuchi , Takashi Sato , Makoto Okita , Yasushi Okamoto , Yumiko Nagasaka , Naoki Kobayashi , Takayuki Hida , Kenji Tai , Naoki Tokuhara , Seiichi Kobayashi
发明人: Katsuya Tagami , Hiroyuki Yoshimura , Mitsuo Nagai , Shigeki Hibi , Kouichi Kikuchi , Takashi Sato , Makoto Okita , Yasushi Okamoto , Yumiko Nagasaka , Naoki Kobayashi , Takayuki Hida , Kenji Tai , Naoki Tokuhara , Seiichi Kobayashi
IPC分类号: C07C69/76 , C07C69/94 , C07D207/32 , C07D207/337 , C07D307/54 , C07D333/24 , C07D405/04 , C07D405/10 , C07D405/14 , C07D407/04 , C07D409/04 , C07D409/10 , C07D409/14 , A61K31/40 , C07D207/30
CPC分类号: C07D207/337 , C07C69/76 , C07C69/94 , C07D307/54 , C07D333/24 , C07D405/04 , C07D405/10 , C07D405/14 , C07D407/04 , C07D409/04 , C07D409/10 , C07D409/14
摘要: The present invention provides a medicament exhibiting excellent retinoic acid receptor agonism.A Carboxylic acid derivative having a fused ring which is represented by the following formula or a pharmacologically acceptable salt thereof: ##STR1## {wherein the symbol ##STR2## represents a single bond or a double bond; X, Y, Z, P, Q, U, V and W are each a group represented by the formula: --O-- or --S--, or a group represented by the formula: ##STR3## [wherein R.sup.k (k: 1 to 8) is hydrogen, halogeno, optionally substituted lower alkyl or the like, with either of R.sup.7 and R.sup.8 being a group represented by the formula: ##STR4## (wherein A and B are each independently an optionally substituted aromatic hydrocarbon ring or an optionally substituted unsaturated heterocycle; and D is optionally protected carboxyl)]}.
摘要翻译: 本发明提供了显示出优异的视黄酸受体激动作用的药物。 具有由下式表示的稠环的羧酸衍生物或其药理学上可接受的盐:其中符号表示单键或双键; X,Y,Z,P,Q,U,V和W分别是由下式表示的基团:-O-或-S-,或由下式表示的基团:[其中R k(k:1至8) 是氢,卤素,任选取代的低级烷基等,其中R 7和R 8中的任一个是由下式表示的基团:(其中A和B各自独立地是任选取代的芳族烃环或任选取代的不饱和杂环; D 任选保护羧基)]}。
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公开(公告)号:US06358995B1
公开(公告)日:2002-03-19
申请号:US09621889
申请日:2000-07-21
申请人: Katsuya Tagami , Hiroyuki Yoshimura , Mitsuo Nagai , Shigeki Hibi , Kouichi Kikuchi , Takashi Sato , Makoto Okita , Yasushi Okamoto , Yumiko Nagasaka , Naoki Kobayashi , Takayuki Hida , Kenji Tai , Naoki Tokuhara , Seiichi Kobayashi
发明人: Katsuya Tagami , Hiroyuki Yoshimura , Mitsuo Nagai , Shigeki Hibi , Kouichi Kikuchi , Takashi Sato , Makoto Okita , Yasushi Okamoto , Yumiko Nagasaka , Naoki Kobayashi , Takayuki Hida , Kenji Tai , Naoki Tokuhara , Seiichi Kobayashi
IPC分类号: A61K3140
CPC分类号: C07D207/337 , C07C69/76 , C07C69/94 , C07D307/54 , C07D333/24 , C07D405/04 , C07D405/10 , C07D405/14 , C07D407/04 , C07D409/04 , C07D409/10 , C07D409/14
摘要: The present invention provides a medicament exhibiting excellent retinoic acid receptor agonism. A Carboxylic acid derivative having a fused ring which is represented by the following formula or a pharmacologically acceptable salt thereof: {wherein the symbol represents a single bond or a double bond; X, Y, Z, P, Q, U, V and W are each a group represented by the formula: —O— or —S—, or a group represented by the formula: [wherein Rk (k: 1 to 8) is hydrogen, halogeno, optionally substituted lower alkyl or the like, with either of R7 and R8 being a group represented by the formula: (wherein A and B are each independently an optionally substituted aromatic hydrocarbon ring or an optionally substituted unsaturated heterocycle; and D is optionally protected carboxyl)]}.
摘要翻译: 本发明提供一种显示出优异的视黄酸受体激动作用的药物。具有下式表示的稠环的羧酸衍生物或其药理学上可接受的盐:{其中符号
表示单键或双键; X,Y,Z,P,Q,U,V和W分别是由下式表示的基团:-O-或-S-,或由下式表示的基团:[其中R k(k:1至8) 是氢,卤素,任选取代的低级烷基等,其中R 7和R 8中的任一个是由下式表示的基团:(其中A和B各自独立地是任选取代的芳族烃环或任选取代的不饱和杂环; D 任选保护羧基)]}。 -
公开(公告)号:US20090215247A1
公开(公告)日:2009-08-27
申请号:US12434637
申请日:2009-05-02
申请人: Takashi Sato , Junichi Takano , Takashi Sato , Tokuo Naitou
发明人: Takashi Sato , Junichi Takano , Takashi Sato , Tokuo Naitou
IPC分类号: H01L21/304
CPC分类号: H01L21/67092 , H01L21/78 , H01L2224/06181 , H01L2224/32245 , H01L2224/45144 , H01L2224/48091 , H01L2224/48247 , H01L2224/73265 , H01L2924/181 , H01L2924/00012 , H01L2924/00
摘要: Illumination devices (7a) and (7b) which irradiate light having a wavelength of 1.1 μm or less are arranged on a front surface and a rear surface of a cover (8) of a dicing device (1). After a wafer is placed on a dicing stage (3), when the wafer is diced by a blade (4a) attached to a spindle (5), light is irradiated on an entire surface of an upper surface (element forming surface) of the wafer by the illumination devices (7a) and (7b). At this time, an illuminance of light on the wafer is set at 70 lux or more and 2000 lux or less. By this means, during a dicing operation, an area to be a light-shielded area by the spindle (5) or the like is not present on the wafer.
摘要翻译: 在扫描装置(1)的盖(8)的前表面和后表面上布置照射波长为1.1μm以下的光的照明装置(7a)和(7b)。 在将晶片放置在切割台(3)上之后,当通过安装在主轴(5)上的刀片(4a)切割晶片时,将光照射在上表面(元件形成表面)的整个表面上 晶片通过照明装置(7a)和(7b)。 此时,晶片上的光的照度设定为70勒克司以上且2000lux以下。 通过这种方式,在切割操作期间,晶片上不存在由主轴(5)等构成遮光区域的区域。
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公开(公告)号:US07998793B2
公开(公告)日:2011-08-16
申请号:US12434637
申请日:2009-05-02
申请人: Takashi Sato , Junichi Takano , Takashi Sato , Tokuo Naitou
发明人: Takashi Sato , Junichi Takano , Takashi Sato , Tokuo Naitou
IPC分类号: H01L21/00
CPC分类号: H01L21/67092 , H01L21/78 , H01L2224/06181 , H01L2224/32245 , H01L2224/45144 , H01L2224/48091 , H01L2224/48247 , H01L2224/73265 , H01L2924/181 , H01L2924/00012 , H01L2924/00
摘要: Illumination devices (7a) and (7b) which irradiate light having a wavelength of 1.1 μm or less are arranged on a front surface and a rear surface of a cover (8) of a dicing device (1). After a wafer is placed on a dicing stage (3), when the wafer is diced by a blade (4a) attached to a spindle (5), light is irradiated on an entire surface of an upper surface (element forming surface) of the wafer by the illumination devices (7a) and (7b). At this time, an illuminance of light on the wafer is set at 70 lux or more and 2000 lux or less. By this means, during a dicing operation, an area to be a light-shielded area by the spindle (5) or the like is not present on the wafer.
摘要翻译: 在切割装置(1)的盖(8)的前表面和后表面上布置照射波长为1.1μm以下的光的照明装置(7a)和(7b)。 在将晶片放置在切割台(3)上之后,当通过安装在主轴(5)上的刀片(4a)切割晶片时,将光照射在上表面(元件形成表面)的整个表面上 晶片通过照明装置(7a)和(7b)。 此时,晶片上的光的照度设定为70勒克司以上且2000lux以下。 通过这种方式,在切割操作期间,晶片上不存在由主轴(5)等构成遮光区域的区域。
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公开(公告)号:US20080138962A1
公开(公告)日:2008-06-12
申请号:US11632993
申请日:2004-07-22
申请人: Takashi Sato , Junichi Takano , Takashi Sato , Tokuo Naitou
发明人: Takashi Sato , Junichi Takano , Takashi Sato , Tokuo Naitou
IPC分类号: H01L21/304
CPC分类号: H01L21/67092 , H01L21/78 , H01L2224/06181 , H01L2224/32245 , H01L2224/45144 , H01L2224/48091 , H01L2224/48247 , H01L2224/73265 , H01L2924/181 , H01L2924/00012 , H01L2924/00
摘要: Illumination devices (7a) and (7b) which irradiate light having a wavelength of 1.1 μm or less are arranged on a front surface and a rear surface of a cover (8) of a dicing device (1). After a wafer is placed on a dicing stage (3), when the wafer is diced by a blade (4a) attached to a spindle (5), light is irradiated on an entire surface of an upper surface (element forming surface) of the wafer by the illumination devices (7a) and (7b). At this time, an illuminance of light on the wafer is set at 70 lux or more and 2000 lux or less. By this means, during a dicing operation, an area to be a light-shielded area by the spindle (5) or the like is not present on the wafer.
摘要翻译: 在切割装置(1)的盖(8)的前表面和后表面上布置照射具有1.1μm或更小的波长的光的照明装置(7a)和(7b)。 在将晶片放置在切割台(3)上之后,当通过安装在主轴(5)上的刀片(4a)切割晶片时,将光照射在上表面(元件形成表面)的整个表面上 通过照明装置(7a)和(7b)的晶片。 此时,晶片上的光的照度设定为70勒克司以上且2000lux以下。 通过这种方式,在切割操作期间,晶片上不存在由主轴(5)等构成遮光区域的区域。
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公开(公告)号:US10026968B2
公开(公告)日:2018-07-17
申请号:US14000569
申请日:2012-01-04
申请人: Masaki Horikita , Kunchan Lee , Yasuaki Wakizaka , Takashi Sato
发明人: Masaki Horikita , Kunchan Lee , Yasuaki Wakizaka , Takashi Sato
IPC分类号: H01M4/88 , H01M4/90 , H01M8/1018
CPC分类号: H01M4/8882 , H01M4/8825 , H01M4/9008 , H01M4/9016 , H01M4/9083 , H01M2008/1095
摘要: A method for producing a fuel cell electrode catalyst, including a step (I) of bringing an aqueous solution of a transition metal compound (1) into contact with ammonia and/or ammonia water to generate a precipitate (A) containing an atom of the transition metal, a step (II) of mixing at least the precipitate (A), an organic compound (B), and a liquid medium (C) to obtain a catalyst precursor liquid, and a step (IV) of subjecting the solid in the catalyst precursor liquid to heat treatment at a temperature of 500 to 1200° C. to obtain an electrode catalyst; a portion or the entirety of the transition metal compound (1) being a compound containing a transition metal element of group 4 or group 5 of the periodic table; and the organic compound (B) being at least one selected from sugars and the like.
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公开(公告)号:US09818495B2
公开(公告)日:2017-11-14
申请号:US13988966
申请日:2011-09-14
申请人: Takashi Sato
发明人: Takashi Sato
摘要: A containment vessel has an inner shell covering a reactor pressure vessel and an outer shell forming an outer well which is a gas-tight space covering the horizontal outer periphery of the inner shell. The inner shell has a first cylindrical side wall surrounding the horizontal periphery of the reactor pressure vessel, a containment vessel head which covers the upper part of the reactor pressure vessel, and a first top slab connecting in a gas-tight manner the periphery of the containment vessel head and the upper end of the first cylindrical side wall. The outer shell has a second cylindrical side wall surrounding the outer periphery of the first cylindrical side wall, and also has a second to slab connecting in a gas-tight manner the vicinity of the upper end of the second cylindrical side wall and the first cylindrical side wall.
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公开(公告)号:US09653994B2
公开(公告)日:2017-05-16
申请号:US13215035
申请日:2011-08-22
申请人: Katsumi Taguchi , Takashi Sato
发明人: Katsumi Taguchi , Takashi Sato
摘要: A power supply device supplying power to a device via a power line is provided, where the power supply device includes a first voltage generation unit configured to generate and supply a first direct voltage to the power line, a second voltage generation unit configured to generate and supply a second direct voltage lower than the first direct voltage to the power line, a measurement unit configured to measure a voltage of the power line, a control unit configured to control supply of the first direct voltage with the first voltage generation unit after starting supply of the second direct voltage with the second voltage generation unit, and a determination unit configured to determine a state of the power supply device based on the measured voltage and a first threshold value after starting the supply of the second direct voltage.
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