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公开(公告)号：US20210169789A1
公开(公告)日：2021-06-10
申请号：US16707670
申请日：2019-12-09
发明人： Darrell Eugene Holton, JR. , Dwayne William Beeson , John E. Bunch , Anthony Richard Gerardi , Chris J. Grimes , Ronald K. Hutchens , Christopher Keller , Thomas H. Poole , Allen Riggins , Frank Kelley St. Charles , Cynthia Stokes
摘要： The disclosure provides for solid products configured for oral use, the products including a carrier material; a releasable material; and wherein the releasable material is combined with the carrier material such that the releasable material is configured for sustained release from the solid product when the solid product is positioned in an oral cavity for a consumer. In another aspect, the disclosure provides for a method of preparing a solid product for oral use, the method comprising providing a releasable material in sprayable form; providing a pouch formed of a fibrous material; and spraying a flavor component onto a least a portion of the pouch one or both of before and after filling the pouch with the oral composition.
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公开(公告)号：US20210177042A1
公开(公告)日：2021-06-17
申请号：US17185119
申请日：2021-02-25
发明人： Chris J. Grimes , Dwayne William Beeson , John E. Bunch , Darrell Eugene Holton, JR. , Ronald K. Hutchens , Allen Riggins , Cynthia Stokes
摘要： The disclosure provides oral compositions and products formed therewith. Such compositions and products may include a first content of a flavor component having a first release rate and a second content of a flavor component having a second, different release rate. The disclosure further provides methods of preparing compositions and products for oral use. Such methods may include spray-drying a liquid flavor component to form particles of the liquid flavor component and mixing the particles of the liquid flavor component with a long-chain carbohydrate. Such methods also may include combining a content of a first flavor component, a content of a second flavor component, and a filler to form a composition suitable for insertion into an oral cavity. The compositions may be formed such that the first flavor component has a first release profile, and the second flavor component has a second, different release profile.
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公开(公告)号：US20210169785A1
公开(公告)日：2021-06-10
申请号：US16707225
申请日：2019-12-09
发明人： Darrell Eugene Holton, JR. , Ronald K. Hutchens , Christopher Keller , Thomas H. Poole , Dwayne William Beeson , Frank Kelley St. Charles , Chris J. Grimes , Anthony Richard Gerardi
IPC分类号： A61K9/00 , A24B13/00 , A24B15/16 , A61K31/522 , A61K36/258 , A61K31/465 , A61K47/36
摘要： The disclosure provides for oral compositions and products that can have a relatively low water content and/or a relatively low water activity. Such compositions and products can comprise at least one active ingredient, a filler/carrier component, and water in an amount of less than 10% by weight, based on the total weight of the composition. Further, the compositions and products can have a water activity of about 0.85 or less.
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公开(公告)号：US20210177754A1
公开(公告)日：2021-06-17
申请号：US17185087
申请日：2021-02-25
发明人： Christopher Keller , Ronald K. Hutchens , Thomas H. Poole , Nicolas von Cosmos , Anthony Richard Gerardi , Chris J. Grimes , Steven Lee Alderman , Darrell Eugene Holton, JR.
IPC分类号： A61K9/107 , A61K31/60 , A61K31/192 , A61K47/14 , A61K47/44 , A61K47/24 , A61K47/26 , A61K47/36 , A61K47/42 , A61K9/51 , A61K31/167 , A61K9/00 , A24B13/00 , A24B15/16
摘要： The disclosure provides a nanoemulsion including an oil, water, an emulsifying agent, and an active ingredient, flavorant, or a combination thereof. The nanoemulsion is intended for human oral use.
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公开(公告)号：US20210169125A1
公开(公告)日：2021-06-10
申请号：US17170986
申请日：2021-02-09
发明人： Darrell Eugene Holton, JR. , Anthony Richard Gerardi , Chris J. Grimes , Ronald K. Hutchens , Christopher Keller , Thomas H. Poole , Frank Kelley St. Charles
摘要： The disclosure provides products configured for oral use, the products including compositions containing an active ingredient and a filler component. The oral products are configured to release at least a portion of the active ingredient when positioned within an oral cavity of a consumer. The release of the active ingredient may be a relatively fast release or a relatively slow release.
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公开(公告)号：US20220295860A1
公开(公告)日：2022-09-22
申请号：US17836790
申请日：2022-06-09
发明人： Darrell Eugene Holton, JR. , Ronald K. Hutchens , Christopher Keller , Thomas H. Poole , Dwayne William Beeson , Frank Kelley St. Charles , Chris J. Grimes , Anthony Richard Gerardi
IPC分类号： A24B15/16 , A24B15/24 , A61K9/00 , A61K31/455 , A61K31/522
摘要： The disclosure provides for oral compositions and products that can have a relatively low water content and/or a relatively low water activity. Such compositions and products can comprise at least one active ingredient, a filler/carrier component, and water in an amount of less than 10% by weight, based on the total weight of the composition. Further, the compositions and products can have a water activity of about 0.85 or less.
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公开(公告)号：US20220295859A1
公开(公告)日：2022-09-22
申请号：US17836692
申请日：2022-06-09
发明人： Darrell Eugene Holton, JR. , Dwayne William Beeson , Anthony Richard Gerardi , Chris J. Grimes , Ronald K. Hutchens , Christopher Keller , Thomas H. Poole , Frank Kelley St. Charles
摘要： The disclosure provides products configured for oral use, the products including one or more active ingredients and a beet material, at least a portion of the one or more active ingredients being bound to the beet material. In some embodiments, oral products as described herein may include a beet material, a filler material, and one or more active ingredients, at least a portion of the one or more active ingredients being bound to the beet material and the filler material. Active ingredients included in the product may be configured for release according to different release rates, which rates may depend at least in part on the material to which the active ingredient is bound.
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公开(公告)号：US20210169786A1
公开(公告)日：2021-06-10
申请号：US16707319
申请日：2019-12-09
发明人： Darrell Eugene Holton, JR. , Dwayne William Beeson , Anthony Richard Gerardi , Chris J. Grimes , Ronald K. Hutchens , Christopher Keller , Thomas H. Poole , Frank Kelley St. Charles
摘要： The disclosure provides products configured for oral use, the products including one or more active ingredients and a beet material, at least a portion of the one or more active ingredients being bound to the beet material. In some embodiments, oral products as described herein may include a beet material, a filler material, and one or more active ingredients, at least a portion of the one or more active ingredients being bound to the beet material and the filler material. Active ingredients included in the product may be configured for release according to different release rates, which rates may depend at least in part on the material to which the active ingredient is bound.
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公开(公告)号：US20220295874A1
公开(公告)日：2022-09-22
申请号：US17834994
申请日：2022-06-08
发明人： Darrell Eugene Holton, JR. , Dwayne William Beeson , John E. Bunch , Anthony Richard Gerardi , Chris J. Grimes , Ronald K. Hutchens , Christopher Keller , Thomas H. Poole , Allen Riggins , Frank Kelley St. Charles , Cynthia Stokes
摘要： The disclosure provides for solid products configured for oral use, the products including a carrier material; a releasable material; and wherein the releasable material is combined with the carrier material such that the releasable material is configured for sustained release from the solid product when the solid product is positioned in an oral cavity for a consumer. In another aspect, the disclosure provides for a method of preparing a solid product for oral use, the method comprising providing a releasable material in sprayable form; providing a pouch formed of a fibrous material; and spraying a flavor component onto a least a portion of the pouch one or both of before and after filling the pouch with the oral composition.
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公开(公告)号：US20210177036A1
公开(公告)日：2021-06-17
申请号：US17185144
申请日：2021-02-25
发明人： Savannah Johnson , Ronald K. Hutchens , David Neil McClanahan , Pankaj Patel , Travis O'Neal , Dwayne William Beeson , Wesley Steven Jones , Christopher Keller , Thomas H. Poole , Nicolas von Cosmos , Anthony Richard Gerardi , Chris J. Grimes , Steven Lee Alderman , Darrell Eugene Holton, JR.
摘要： The disclosure provides a pouched product including a chromogenic material or an electronic component, wherein the chromogenic material and the electronic component are responsive to a stimulus. Such products can be employed to detect various changes associated with the pouched product.
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