公开(公告)号：US20210113552A1

公开(公告)日：2021-04-22

申请号：US17073603

申请日：2020-10-19

Applicant: NORTHWESTERN UNIVERSITY

Inventor： Joseph R. Mazzulli ,  Leah K. Cuddy

IPC: A61K31/4709 ,  A61P25/16 ,  G01N33/68 ,  A61K31/454

Abstract: Disclosed are methods and compositions for enhancing cellular clearance of pathological molecules. Particularly disclosed are methods and compositions enhancing cellular clearance of pathological molecules via activating the cellular protein ykt6. The disclosed methods and compositions may be utilized in order to treat a subject having or at risk for developing a proteinopathy or other cellular storage disorder.

公开(公告)号：US12226410B2

公开(公告)日：2025-02-18

申请号：US17073603

申请日：2020-10-19

Applicant: NORTHWESTERN UNIVERSITY

Inventor： Joseph R. Mazzulli ,  Leah K. Cuddy

IPC: A61K31/4709 ,  A61K31/454 ,  A61P25/16 ,  G01N33/68

Abstract: Disclosed are methods and compositions for enhancing cellular clearance of pathological molecules. Particularly disclosed are methods and compositions enhancing cellular clearance of pathological molecules via activating the cellular protein ykt6. The disclosed methods and compositions may be utilized in order to treat a subject having or at risk for developing a proteinopathy or other cellular storage disorder.