-
公开(公告)号:US20150197519A1
公开(公告)日:2015-07-16
申请号:US14596987
申请日:2015-01-14
IPC分类号: C07D471/04 , C07D217/16 , C07D403/04 , C07D413/04 , C07D239/74
CPC分类号: C07D471/04 , A61K31/517 , C07D217/14 , C07D217/16 , C07D239/74 , C07D403/04 , C07D413/04 , C07D487/04 , C07D487/14
摘要: Described herein are inhibitors of FGFR-4, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions to inhibit the activity of FGFR-4.
摘要翻译: 本文描述了FGFR-4的抑制剂,包括这些化合物的药物组合物,以及使用这些化合物和组合物抑制FGFR-4活性的方法。
-
公开(公告)号:US09434700B2
公开(公告)日:2016-09-06
申请号:US14521909
申请日:2014-10-23
IPC分类号: C07D405/12 , A61K31/517 , C07D239/84 , C07D401/12 , C07D403/12 , C07D403/14 , C07D471/04 , C07D401/04 , C07D475/00 , C07D235/30 , C07D409/12 , C07D475/08
CPC分类号: C07D401/04 , C07D235/30 , C07D239/84 , C07D401/12 , C07D403/12 , C07D403/14 , C07D405/12 , C07D409/12 , C07D471/04 , C07D475/00
摘要: Described herein are inhibitors of FGFR-4, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions.
摘要翻译: 本文描述的是FGFR-4的抑制剂,包括这些化合物的药物组合物,以及使用这些化合物和组合物的方法。
-
公开(公告)号:US20150119405A1
公开(公告)日:2015-04-30
申请号:US14521909
申请日:2014-10-23
IPC分类号: C07D239/84 , C07D403/12 , C07D471/04 , C07D405/12 , C07D475/00 , C07D401/04
CPC分类号: C07D401/04 , C07D235/30 , C07D239/84 , C07D401/12 , C07D403/12 , C07D403/14 , C07D405/12 , C07D409/12 , C07D471/04 , C07D475/00
摘要: Described herein are inhibitors of FGFR-4, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions.
摘要翻译: 本文描述的是FGFR-4的抑制剂,包括这些化合物的药物组合物,以及使用这些化合物和组合物的方法。
-
公开(公告)号:US09499522B2
公开(公告)日:2016-11-22
申请号:US14210526
申请日:2014-03-14
申请人: Lucian V. DiPietro , Brian L. Hodous , Joseph L. Kim , Chandrasekhar V. Miduturu , Steven Mark Wenglowsky , Douglas Wilson , Yulian Zhang
发明人: Lucian V. DiPietro , Brian L. Hodous , Joseph L. Kim , Chandrasekhar V. Miduturu , Steven Mark Wenglowsky , Douglas Wilson , Yulian Zhang
IPC分类号: C07D403/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D487/04 , C07D487/08 , C07D401/12 , C07D403/04 , C07D403/14 , C07D239/94 , C07D487/22
CPC分类号: C07D403/14 , C07D239/94 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D473/34 , C07D487/04 , C07D487/08 , C07D487/22
摘要: Compounds and compositions useful for treating disorders related to Kit are described herein.
摘要翻译: 本文描述了可用于治疗与Kit相关的疾病的化合物和组合物。
-
公开(公告)号:US20140296206A1
公开(公告)日:2014-10-02
申请号:US14210526
申请日:2014-03-14
申请人: Lucian V. DiPietro , Brian L. Hodous , Joseph L. Kim , Chandrasekhar V. Miduturu , Steven Mark Wenglowsky , Douglas Wilson , Yulian Zhang
发明人: Lucian V. DiPietro , Brian L. Hodous , Joseph L. Kim , Chandrasekhar V. Miduturu , Steven Mark Wenglowsky , Douglas Wilson , Yulian Zhang
IPC分类号: C07D403/12 , C07D487/08 , C07D413/14 , C07D409/14 , C07D405/14 , C07D487/04 , C07D401/14
CPC分类号: C07D403/14 , C07D239/94 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D473/34 , C07D487/04 , C07D487/08 , C07D487/22
摘要: Compounds and compositions useful for treating disorders related to Kit are described herein.
摘要翻译: 本文描述了可用于治疗与Kit相关的疾病的化合物和组合物。
-
公开(公告)号:US20140088100A1
公开(公告)日:2014-03-27
申请号:US13939967
申请日:2013-07-11
申请人: Neil Bifulco, JR. , Natasja Brooijmans , Brian L. Hodous , Joseph L. Kim , Chandrasekhar V. Miduturu
发明人: Neil Bifulco, JR. , Natasja Brooijmans , Brian L. Hodous , Joseph L. Kim , Chandrasekhar V. Miduturu
IPC分类号: C07D487/04 , C07D295/155 , C07D475/00 , C07D239/84 , C07D471/04
CPC分类号: C07K14/71 , A61K31/4375 , A61K31/517 , A61K31/519 , C07D239/42 , C07D239/84 , C07D295/155 , C07D401/04 , C07D471/04 , C07D475/00 , C07D475/04 , C07D487/04
摘要: Described herein are inhibitors of FGFR, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions to inhibit the activity of tyrosine kinases.
摘要翻译: 本文描述的是FGFR的抑制剂,包括这些化合物的药物组合物,以及使用这些化合物和组合物抑制酪氨酸激酶活性的方法。
-
公开(公告)号:US09126951B2
公开(公告)日:2015-09-08
申请号:US14318149
申请日:2014-06-27
申请人: Neil Bifulco, Jr. , Natasja Brooijmans , Brian L. Hodous , Joseph L. Kim , Chandrasekhar V. Miduturu
发明人: Neil Bifulco, Jr. , Natasja Brooijmans , Brian L. Hodous , Joseph L. Kim , Chandrasekhar V. Miduturu
IPC分类号: A61K31/4375 , C07D239/84 , C07D239/42 , C07D471/04 , C07D475/00 , C07D487/04 , A61K31/517 , A61K31/519
CPC分类号: C07K14/71 , A61K31/4375 , A61K31/517 , A61K31/519 , C07D239/42 , C07D239/84 , C07D295/155 , C07D401/04 , C07D471/04 , C07D475/00 , C07D475/04 , C07D487/04
摘要: Described herein are inhibitors of FGFR, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions to inhibit the activity of tyrosine kinases.
摘要翻译: 本文描述的是FGFR的抑制剂,包括这些化合物的药物组合物,以及使用这些化合物和组合物抑制酪氨酸激酶活性的方法。
-
公开(公告)号:US20150210694A1
公开(公告)日:2015-07-30
申请号:US14677162
申请日:2015-04-02
申请人: Neil Bifulco, JR. , Natasja Brooijmans , Brian L. Hodous , Joseph L. Kim , Chandrasekhar V. Miduturu
发明人: Neil Bifulco, JR. , Natasja Brooijmans , Brian L. Hodous , Joseph L. Kim , Chandrasekhar V. Miduturu
IPC分类号: C07D475/00 , C07D401/04 , C07D239/42 , C07D239/84 , C07D471/04
CPC分类号: C07K14/71 , A61K31/4375 , A61K31/517 , A61K31/519 , C07D239/42 , C07D239/84 , C07D295/155 , C07D401/04 , C07D471/04 , C07D475/00 , C07D475/04 , C07D487/04
摘要: Described herein are inhibitors of FGFR, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions to inhibit the activity of tyrosine kinases.
摘要翻译: 本文描述的是FGFR的抑制剂,包括这些化合物的药物组合物,以及使用这些化合物和组合物抑制酪氨酸激酶活性的方法。
-
公开(公告)号:US20140378481A1
公开(公告)日:2014-12-25
申请号:US14318149
申请日:2014-06-27
申请人: Neil Bifulco, JR. , Natasja Brooijmans , Brian L. Hodous , Joseph L. Kim , Chandrasekhar V. Miduturu
发明人: Neil Bifulco, JR. , Natasja Brooijmans , Brian L. Hodous , Joseph L. Kim , Chandrasekhar V. Miduturu
IPC分类号: C07D239/84 , A61K31/4375 , A61K31/519 , A61K31/517 , C07D471/04
CPC分类号: C07K14/71 , A61K31/4375 , A61K31/517 , A61K31/519 , C07D239/42 , C07D239/84 , C07D295/155 , C07D401/04 , C07D471/04 , C07D475/00 , C07D475/04 , C07D487/04
摘要: Described herein are inhibitors of FGFR, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions to inhibit the activity of tyrosine kinases.
-
公开(公告)号:US08802697B2
公开(公告)日:2014-08-12
申请号:US13939967
申请日:2013-07-11
申请人: Neil Bifulco, Jr. , Natasja Brooijmans , Brian L. Hodous , Joseph L. Kim , Chandrasekhar V. Miduturu
发明人: Neil Bifulco, Jr. , Natasja Brooijmans , Brian L. Hodous , Joseph L. Kim , Chandrasekhar V. Miduturu
IPC分类号: A01N43/42 , A61K31/44 , C07D487/04 , C07D239/84 , C07D475/00 , C07D239/42 , C07D295/155 , C07D471/04
CPC分类号: C07K14/71 , A61K31/4375 , A61K31/517 , A61K31/519 , C07D239/42 , C07D239/84 , C07D295/155 , C07D401/04 , C07D471/04 , C07D475/00 , C07D475/04 , C07D487/04
摘要: Described herein are inhibitors of FGFR, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions to inhibit the activity of tyrosine kinases.
摘要翻译: 本文描述的是FGFR的抑制剂,包括这些化合物的药物组合物,以及使用这些化合物和组合物抑制酪氨酸激酶活性的方法。
-
-
-
-
-
-
-
-
-