Polymeric cannulae proteins, nucleic acids encoding them and methods for making and using them
    1.
    发明申请
    Polymeric cannulae proteins, nucleic acids encoding them and methods for making and using them 审中-公开
    聚合插管蛋白,编码它们的核酸以及制备和使用它们的方法

    公开(公告)号:US20050208121A1

    公开(公告)日:2005-09-22

    申请号:US11046203

    申请日:2005-01-28

    摘要: The invention provides chimeric cannulae polypeptides and methods for making and using them. In one aspect, the invention provides compositions and methods for the identification, separation or synthesis of proteins or ligands. In one aspect, the invention provides compositions and methods for making and using nanotubules. In one aspect, the invention provides compositions and methods for the selection and purification of chiral compositions from racemic mixtures. The invention provides compositions comprising polymers prepared by self-assembly of a plurality of monomeric polypeptide units, including nanorobots, biochips, drug delivery systems. In one aspect, the polymer can form a nanotube, and the polymer (nanotubule) can encapsulate a drug molecule—a drug delivery systems of the invention. A drug delivery system of the invention may be delivered to a particular location of human body to effectively cure a disease or treat a symptom. In one aspect, a targeting vector can be attached to a monomeric polypeptide unit or a polymer to facilitate the targeting of the drug delivery system of the invention.

    摘要翻译: 本发明提供了嵌合插管多肽及其制备和使用方法。 一方面,本发明提供用于鉴定,分离或合成蛋白质或配体的组合物和方法。 一方面,本发明提供了制备和使用纳米管的组合物和方法。 一方面,本发明提供了用于从外消旋混合物中选择和纯化手性组合物的组合物和方法。 本发明提供了包含通过自组装多个单体多肽单元制备的聚合物的组合物,包括纳米机器人,生物芯片,药物递送系统。 在一个方面,聚合物可以形成纳米管,并且聚合物(纳米管)可以包封药物分子 - 本发明的药物递送系统。 本发明的药物递送系统可以被递送到人体的特定位置以有效地治愈疾病或治疗症状。 在一个方面,靶向载体可以连接到单体多肽单元或聚合物以促进本发明的药物递送系统的靶向。

    Oil degumming methods
    8.
    发明授权
    Oil degumming methods 有权
    油脱胶方法

    公开(公告)号:US09045712B2

    公开(公告)日:2015-06-02

    申请号:US13502105

    申请日:2010-10-08

    摘要: In alternative embodiments, the invention provides phosphatidylinositol-specific phospholipase C (PI-PLC) enzymes, nucleic acids encoding them, antibodies that bind specifically to them, and methods for making and using them. Industrial methods and products comprising use of these phospholipases are also provided. In certain embodiments, provided herein are methods for hydration of non hydratable phospholipids (NHPs) within a lipid matrix. The methods enable migration of NHPs to an oil-water interface thereby allowing the NHPs to be reacted and/or removed from the lipids. In certain embodiments, provided is a method for removing NHPs, hydratable phospholipids, and lecithins from vegetable oils to produce a degummed oil or fat product that can be used for food production and/or non-food applications. In certain embodiments, provided herein are methods for hydration of NHPs followed by enzymatic treatment and removal of various phospholipids and lecithins. The methods provided herein can be practiced on either crude or water-degummed oils.

    摘要翻译: 在替代实施方案中,本发明提供磷脂酰肌醇特异性磷脂酶C(PI-PLC)酶,编码它们的核酸,与其特异性结合的抗体,以及制备和使用它们的方法。 还提供了包括使用这些磷脂酶的工业方法和产品。 在某些实施方案中,本文提供了用于在脂质基质内水合非水合磷脂(NHP)的方法。 这些方法使NHP迁移到油 - 水界面,从而允许NHP从脂质中反应和/或除去。 在某些实施方案中,提供了从植物油中除去NHP,可水合磷脂和卵磷脂以产生可用于食品生产和/或非食品应用的脱胶油或脂肪产品的方法。 在某些实施方案中,本文提供了用于NHP水合的方法,然后进行酶处理和除去各种磷脂和卵磷脂。 本文提供的方法可以在粗脱水油或水脱胶油上实施。

    OIL DEGUMMING METHODS
    10.
    发明申请
    OIL DEGUMMING METHODS 有权
    油分方法

    公开(公告)号:US20130011887A1

    公开(公告)日:2013-01-10

    申请号:US13502105

    申请日:2010-10-08

    摘要: In alternative embodiments, the invention provides phosphatidylinositol-specific phospholipase C (PI-PLC) enzymes, nucleic acids encoding them, antibodies that bind specifically to them, and methods for making and using them. Industrial methods and products comprising use of these phospholipases are also provided. In certain embodiments, provided herein are methods for hydration of non hydratable phospholipids (NHPs) within a lipid matrix. The methods enable migration of NHPs to an oil-water interface thereby allowing the NHPs to be reacted and/or removed from the lipids. In certain embodiments, provided is a method for removing NHPs, hydratable phospholipids, and lecithins from vegetable oils to produce a degummed oil or fat product that can be used for food production and/or non-food applications. In certain embodiments, provided herein are methods for hydration of NHPs followed by enzymatic treatment and removal of various phospholipids and lecithins. The methods provided herein can be practiced on either crude or water-degummed oils.

    摘要翻译: 在替代实施方案中,本发明提供磷脂酰肌醇特异性磷脂酶C(PI-PLC)酶,编码它们的核酸,与其特异性结合的抗体,以及制备和使用它们的方法。 还提供了包括使用这些磷脂酶的工业方法和产品。 在某些实施方案中,本文提供了用于在脂质基质内水合非水合磷脂(NHP)的方法。 这些方法使NHP迁移到油 - 水界面,从而允许NHP从脂质中反应和/或除去。 在某些实施方案中,提供了从植物油中除去NHP,可水合磷脂和卵磷脂以产生可用于食品生产和/或非食品应用的脱胶油或脂肪产品的方法。 在某些实施方案中,本文提供了用于NHP水合的方法,然后进行酶处理和除去各种磷脂和卵磷脂。 本文提供的方法可以在粗脱水油或水脱胶油上实施。