ROLE OF DH44 AND HOMOLOGS IN CALORIE SENSING
    2.
    发明申请
    ROLE OF DH44 AND HOMOLOGS IN CALORIE SENSING 审中-公开
    DH44和HOMOLOGS在CALORIE感觉中的作用

    公开(公告)号:US20150231276A1

    公开(公告)日:2015-08-20

    申请号:US14624208

    申请日:2015-02-17

    IPC分类号: A61K49/00

    摘要: Provided are methods for identifying Drosophila melanogaster mutants which have mutations affecting calorie sensing behavior. Also provided are methods for identifying agents that can interfere with calorie sensing behavior in D. melanogaster and in mammals. Also provided are methods to identify agents that affect neuronal response of Dh44 neurons or CRF neurons to metabolizing sugars.

    摘要翻译: 提供了用于鉴定具有影响卡路里感测行为的突变的果蝇黑腹果蝇突变体的方法。 还提供了用于鉴定可以干扰黑腹果蝇和哺乳动物中的热量感测行为的试剂的方法。 还提供了鉴定影响Dh44神经元或CRF神经元代谢糖的神经元反应的试剂的方法。