公开(公告)号：US08518106B2

公开(公告)日：2013-08-27

申请号：US13016865

申请日：2011-01-28

申请人： Niall Duffy ,  Gerry McCaffrey ,  John Gallagher ,  Kate Corish ,  Ronan Rogers ,  Mark Casley ,  Gavin Kenny

发明人： Niall Duffy ,  Gerry McCaffrey ,  John Gallagher ,  Kate Corish ,  Ronan Rogers ,  Mark Casley ,  Gavin Kenny

IPC分类号： A61F2/24

CPC分类号： A61F2/2427 ,  A61F2/2436 ,  A61F2/95 ,  A61F2/966 ,  A61F2002/9517

摘要： Valve delivery catheter assemblies including components that limit trauma to the expanded prosthetic valve and body channels as the distal tip of the catheter is withdrawn through the expanded valve and thereafter from the body. In one embodiment, a catheter assembly according to the present invention includes a handle assembly, an introducer sheath, and a distal tip assembly. The handle assembly can include a fixed main handle and two or more rotating handles that allow a user to control the distal tip assembly of the catheter. A valve retaining mechanism can be included to assist in retaining the prosthetic valve prior to deployment. Each control knob on the handle assembly controls a portion of the components on the distal tip of the catheter by allowing for precise manipulation of various delivery shafts. Each delivery shaft extends from the handle assembly to respective positions towards the distal end of the catheter.

摘要翻译： 瓣膜输送导管组件包括当导管的远端通过膨胀的瓣膜然后从身体排出时限制扩张的假体瓣膜和主体通道的创伤的部件。 在一个实施例中，根据本发明的导管组件包括手柄组件，导引器套和远侧末端组件。 手柄组件可以包括固定的主手柄和允许使用者控制导管的远侧末端组件的两个或更多个旋转手柄。 可以包括阀保持机构以在展开之前辅助保留人造瓣膜。 手柄组件上的每个控制旋钮通过允许各种输送轴的精确操纵来控制导管的远侧末端上的部件的一部分。 每个输送轴从手柄组件延伸到相对于导管远端的位置。

公开(公告)号：US20120035717A1

公开(公告)日：2012-02-09

申请号：US13016865

申请日：2011-01-28

申请人： Niall Duffy ,  Gerry McCaffrey ,  John Gallagher ,  Kate Corish ,  Ronan Rogers ,  Mark CASLEY ,  Gavin Kenny

发明人： Niall Duffy ,  Gerry McCaffrey ,  John Gallagher ,  Kate Corish ,  Ronan Rogers ,  Mark CASLEY ,  Gavin Kenny

IPC分类号： A61F2/24

CPC分类号： A61F2/2427 ,  A61F2/2436 ,  A61F2/95 ,  A61F2/966 ,  A61F2002/9517

摘要： Valve delivery catheter assemblies including components that limit trauma to the expanded prosthetic valve and body channels as the distal tip of the catheter is withdrawn through the expanded valve and thereafter from the body. In one embodiment, a catheter assembly according to the present invention includes a handle assembly, an introducer sheath, and a distal tip assembly. The handle assembly can include a fixed main handle and two or more rotating handles that allow a user to control the distal tip assembly of the catheter. A valve retaining mechanism can be included to assist in retaining the prosthetic valve prior to deployment. Each control knob on the handle assembly controls a portion of the components on the distal tip of the catheter by allowing for precise manipulation of various delivery shafts. Each delivery shaft extends from the handle assembly to respective positions towards the distal end of the catheter.

摘要翻译： 瓣膜输送导管组件包括当导管的远端通过膨胀的瓣膜然后从身体排出时限制对扩张的假体瓣膜和主体通道的创伤的部件。 在一个实施例中，根据本发明的导管组件包括手柄组件，导引器套和远侧末端组件。 手柄组件可以包括固定的主手柄和允许使用者控制导管的远侧末端组件的两个或更多个旋转手柄。 可以包括阀保持机构以在展开之前辅助保留人造瓣膜。 手柄组件上的每个控制旋钮通过允许各种输送轴的精确操纵来控制导管的远侧末端上的部件的一部分。 每个输送轴从手柄组件延伸到相对于导管远端的位置。

公开(公告)号：US20140031922A1

公开(公告)日：2014-01-30

申请号：US13557488

申请日：2012-07-25

申请人： Niall Duffy ,  Ronan Rogers ,  John Gallagher ,  Gavin Kenny

发明人： Niall Duffy ,  Ronan Rogers ,  John Gallagher ,  Gavin Kenny

IPC分类号： A61F2/24

CPC分类号： A61F2/966 ,  A61F2/2436 ,  A61F2002/9505 ,  A61F2002/9517 ,  A61F2002/9665

摘要： Heart valve delivery systems and methods of delivering and implanting heart valves using delivery catheters are disclosed. The delivery systems can include a handle assembly with a rotatable control knob and a catheter including an introducer shaft, an intermediate shaft extending from the handle assembly, an inner shaft extending from the handle assembly, and a capsule for containing a prosthesis. The distal end of the capsule can be connected to a distal end of the inner shaft, which can be moved in a distal direction by the rotatable control knob to deploy the prosthesis. By advancing the introducer through the deployed prosthesis and retracting the capsule to mate with the introducer, a smooth profile can be created for retraction of the system through the deployed prosthesis, minimizing hang-ups and snagging.

摘要翻译： 公开了使用输送导管递送和植入心脏瓣膜的心脏瓣膜输送系统和方法。 输送系统可以包括具有可旋转控制旋钮的手柄组件和包括导引器轴的导管，从手柄组件延伸的中间轴，从手柄组件延伸的内轴以及用于容纳假体的胶囊。 胶囊的远端可以连接到内轴的远端，其可以通过可旋转的控制旋钮在远端方向上移动以展开假体。 通过推进引导器穿过部署的假体并缩回胶囊以与导引器配合，可以创建平滑的轮廓，用于通过部署的假体缩回系统，最大限度地减少挂起和阻塞。

公开(公告)号：US09271856B2

公开(公告)日：2016-03-01

申请号：US13557488

申请日：2012-07-25

申请人： Niall Duffy ,  Ronan Rogers ,  John Gallagher ,  Gavin Kenny

发明人： Niall Duffy ,  Ronan Rogers ,  John Gallagher ,  Gavin Kenny

IPC分类号： A61F2/24 ,  A61F2/966 ,  A61F2/95

CPC分类号： A61F2/966 ,  A61F2/2436 ,  A61F2002/9505 ,  A61F2002/9517 ,  A61F2002/9665

摘要： Heart valve delivery systems and methods of delivering and implanting heart valves using delivery catheters are disclosed. The delivery systems can include a handle assembly with a rotatable control knob and a catheter including an introducer shaft, an intermediate shaft extending from the handle assembly, an inner shaft extending from the handle assembly, and a capsule for containing a prosthesis. The distal end of the capsule can be connected to a distal end of the inner shaft, which can be moved in a distal direction by the rotatable control knob to deploy the prosthesis. By advancing the introducer through the deployed prosthesis and retracting the capsule to mate with the introducer, a smooth profile can be created for retraction of the system through the deployed prosthesis, minimizing hang-ups and snagging.

摘要翻译： 公开了使用输送导管递送和植入心脏瓣膜的心脏瓣膜输送系统和方法。 输送系统可以包括具有可旋转控制旋钮的手柄组件和包括导引器轴的导管，从手柄组件延伸的中间轴，从手柄组件延伸的内轴以及用于容纳假体的胶囊。 胶囊的远端可以连接到内轴的远端，其可以通过可旋转的控制旋钮在远端方向上移动以展开假体。 通过推进引导器穿过部署的假体并缩回胶囊以与导引器配合，可以创建平滑的轮廓，用于通过部署的假体缩回系统，最大限度地减少挂起和阻塞。

公开(公告)号：US08926693B2

公开(公告)日：2015-01-06

申请号：US13016658

申请日：2011-01-28

申请人： Niall Duffy ,  John Gallagher ,  Kate Corish

发明人： Niall Duffy ,  John Gallagher ,  Kate Corish

IPC分类号： A61F2/24 ,  A61F2/06 ,  A61F2/966 ,  A61F2/95

CPC分类号： A61F2/2436 ,  A61F2/966 ,  A61F2002/9517

摘要： Valve delivery catheter assemblies including components that limit trauma to the expanded prosthetic valve and body channels as the distal tip of the catheter is withdrawn through the expanded valve and thereafter from the body. Catheter assemblies according to the present invention can include a handle assembly, an introducer sheath, and a distal tip assembly. The handle assembly can include a fixed main handle and two or more rotating handles that allow a user to control the distal tip assembly of the catheter. A safety button can be included on the handle assembly to allow for precise and consistent positioning of the prosthetic valve in the body. A valve retaining mechanism can be included to assist in retaining the prosthetic valve prior to deployment.

摘要翻译： 瓣膜输送导管组件包括当导管的远端通过膨胀的瓣膜然后从身体排出时限制扩张的假体瓣膜和主体通道的创伤的部件。 根据本发明的导管组件可以包括手柄组件，导引器护套和远侧末端组件。 手柄组件可以包括固定的主手柄和允许使用者控制导管的远侧末端组件的两个或更多个旋转手柄。 手柄组件中可以包括安全按钮，以允许人造瓣膜在体内的精确和一致的定位。 可以包括阀保持机构以在展开之前辅助保留人造瓣膜。

公开(公告)号：US20120041547A1

公开(公告)日：2012-02-16

申请号：US13016658

申请日：2011-01-28

申请人： Niall DUFFY ,  John Gallagher ,  Kate Corish

发明人： Niall DUFFY ,  John Gallagher ,  Kate Corish

IPC分类号： A61F2/24

CPC分类号： A61F2/2436 ,  A61F2/966 ,  A61F2002/9517

摘要： Valve delivery catheter assemblies including components that limit trauma to the expanded prosthetic valve and body channels as the distal tip of the catheter is withdrawn through the expanded valve and thereafter from the body. Catheter assemblies according to the present invention can include a handle assembly, an introducer sheath, and a distal tip assembly. The handle assembly can include a fixed main handle and two or more rotating handles that allow a user to control the distal tip assembly of the catheter. A safety button can be included on the handle assembly to allow for precise and consistent positioning of the prosthetic valve in the body. A valve retaining mechanism can be included to assist in retaining the prosthetic valve prior to deployment.

摘要翻译： 瓣膜输送导管组件包括当导管的远端通过膨胀的瓣膜然后从身体排出时限制扩张的假体瓣膜和主体通道的创伤的部件。 根据本发明的导管组件可以包括手柄组件，导引器护套和远侧末端组件。 手柄组件可以包括固定的主手柄和允许使用者控制导管的远侧末端组件的两个或更多个旋转手柄。 手柄组件中可以包括安全按钮，以允许人造瓣膜在体内的精确和一致的定位。 可以包括阀保持机构以在展开之前辅助保留人造瓣膜。

公开(公告)号：US09067050B2

公开(公告)日：2015-06-30

申请号：US13435371

申请日：2012-03-30

申请人： John Gallagher ,  Gerry McCaffrey

发明人： John Gallagher ,  Gerry McCaffrey

IPC分类号： A61M5/00 ,  A61M39/28 ,  A61F2/07 ,  A61M5/168 ,  A61B17/11 ,  A61F5/00

CPC分类号： A61M39/28 ,  A61B17/11 ,  A61B2017/1107 ,  A61B2017/1139 ,  A61F2/07 ,  A61F5/004 ,  A61F2002/072 ,  A61M5/16813

摘要： An arteriovenous shunt assembly including a shunt and a pull wire operated flow control mechanism. The shunt has a tubular body that defines a fluid passageway between a first end and a second end thereof The pull wire mechanism includes a portion disposed around the tubular shunt in at least one loop. The at least one loop may be selectively tightened or loosened remotely from the shunt to regulate the rate of blood flow through the tubular shunt.

摘要翻译： 一种动静脉分流组件，包括分流器和拉线操作的流量控制机构。 分流器具有在第一端和第二端之间限定流体通道的管状体。拉线机构包括在至少一个环中围绕管状分流器设置的部分。 至少一个回路可以从分流器远程选择性地拧紧或松开，以调节通过管状分流器的血液流速。

公开(公告)号：US20130261531A1

公开(公告)日：2013-10-03

申请号：US13435371

申请日：2012-03-30

申请人： John Gallagher ,  Gerry McCaffrey

发明人： John Gallagher ,  Gerry McCaffrey

IPC分类号： A61M5/00 ,  A61F2/06

CPC分类号： A61M39/28 ,  A61B17/11 ,  A61B2017/1107 ,  A61B2017/1139 ,  A61F2/07 ,  A61F5/004 ,  A61F2002/072 ,  A61M5/16813

摘要： An arteriovenous shunt assembly including a shunt and a pull wire operated flow control mechanism. The shunt has a tubular body that defines a fluid passageway between a first end and a second end thereof The pull wire mechanism includes a portion disposed around the tubular shunt in at least one loop. The at least one loop may be selectively tightened or loosened remotely from the shunt to regulate the rate of blood flow through the tubular shunt.

摘要翻译： 一种动静脉分流组件，包括分流器和拉线操作的流量控制机构。 分流器具有在第一端和第二端之间限定流体通道的管状体。拉线机构包括在至少一个环中围绕管状分流器设置的部分。 至少一个回路可以从分流器远程选择性地拧紧或松开，以调节通过管状分流器的血液流速。

公开(公告)号：US08562663B2

公开(公告)日：2013-10-22

申请号：US12912479

申请日：2010-10-26

申请人： Paul Mearns ,  John Gallagher ,  Kevin O'Sullivan ,  Mark Casley ,  Pat Duane

发明人： Paul Mearns ,  John Gallagher ,  Kevin O'Sullivan ,  Mark Casley ,  Pat Duane

IPC分类号： A61F2/24 ,  A61F2/06 ,  A61F5/00

CPC分类号： A61F2/2427 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2002/9522 ,  A61F2220/0075 ,  Y10T29/53843

摘要： In an embodiment, a device for loading a prosthesis onto a delivery system comprises a cap and a reducing member. The cap has a piston member that seats a prosthesis. The piston member has at least one side wall configured to contact a portion of the side of the prosthesis seated therein. The reducing member has a conical wall, a first open end, and a second open end. The first open end is configured to receive the piston member. The reducing member reduces an external dimension of at least a portion of the prosthesis seated in the piston member as the prosthesis is moved along an inner surface of the conical wall.

摘要翻译： 在一个实施例中，用于将假体装载到输送系统上的装置包括盖和还原构件。 盖具有一个活塞构件，用于支撑假体。 所述活塞构件具有至少一个侧壁，所述至少一个侧壁构造成接触其中安置的所述假体的一侧的一部分。 还原构件具有锥形壁，第一开口端和第二开口端。 第一开口端构造成接收活塞构件。 当假体沿着锥形壁的内表面移动时，还原构件减小了坐在活塞构件中的假体的至少一部分的外部尺寸。

公开(公告)号：US20110208296A1

公开(公告)日：2011-08-25

申请号：US12911458

申请日：2010-10-25

申请人： Niall Duffy ,  Paul Mearns ,  John Gallagher ,  Noam Miller

发明人： Niall Duffy ,  Paul Mearns ,  John Gallagher ,  Noam Miller

IPC分类号： A61F2/24 ,  B23Q7/04

CPC分类号： A61F2/2427 ,  A61F2/95 ,  A61F2002/9522 ,  Y10T29/53996

摘要： Catheter assemblies including a handle assembly located on the proximal end of the catheter assembly and a distal tip assembly located on the distal end of the catheter assembly. A crimping funnel is slidably positioned along the catheter. The crimping funnel includes a distal end having a first diameter and a proximal end having a second diameter smaller than the first diameter. An axial split is formed in the proximal end. A first collar is provided encompassing a portion of the proximal end. The first collar is configured to hold the axial split in the proximal end together when the first collar is at a first axial location along the proximal end, and to allow the axial split in the proximal end to open when the first collar is at a second axial location along the proximal end, such that the crimping funnel can be removed from the catheter assembly. Various methods of retaining a prosthetic valve on the catheter assembly during the crimping process are described.

摘要翻译： 导管组件包括位于导管组件的近端上的把手组件和位于导管组件的远端上的远侧末端组件。 压接漏斗沿着导管可滑动地定位。 卷曲漏斗包括具有第一直径的远端和具有小于第一直径的第二直径的近端。 在近端形成轴向分裂。 提供包围近端的一部分的第一套环。 当第一颈圈沿着近端位于第一轴向位置时，第一颈圈被构造成将近端中的轴向分裂保持在一起，并且当第一颈圈在第二颈圈处于第二颈圈时允许近端中的轴向分裂打开 沿着近端的轴向位置，使得可以从导管组件移除压接漏斗。 描述了在压接过程期间将修复瓣膜保持在导管组件上的各种方法。