公开(公告)号：US6048332A

公开(公告)日：2000-04-11

申请号：US169340

申请日：1998-10-09

申请人： Niall Duffy ,  Micheal O'Loughlin

发明人： Niall Duffy ,  Micheal O'Loughlin

IPC分类号： A61F2/958 ,  A61M29/00

CPC分类号： A61M25/1002 ,  A61M2025/105 ,  A61M2025/1086

摘要： The systems and methods described herein include drug delivery catheters that have dimpled porous balloons mounted onto the distal end of the catheter. In one embodiment, the balloons are adapted for delivering therapeutic agents to the tissue wall of a body lumen, and to this end include a plurality of dimples formed in the exterior surface of the balloon, with each dimple having at least one aperture through which a fluid delivered into the interior of the balloon can extravasate. It is understood that the balloons described herein provide, inter alia, increased coverage of the tissue wall to which the agent is being delivered and less traumatic contact between the agent being delivered and the tissue wall.

摘要翻译： 本文所述的系统和方法包括具有安装在导管远端上的凹陷多孔气球的药物输送导管。 在一个实施例中，气囊适于将治疗剂递送到体腔的组织壁，并且为此，包括形成在气囊的外表面中的多个凹坑，每个凹窝具有至少一个孔，通过该孔 输送到气囊内部的液体可能外渗。 应当理解，本文所述的气囊尤其提供了递送药剂的组织壁的增加的覆盖率，并且递送的药剂与组织壁之间的创伤性接触较少。