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公开(公告)号：USD602586S1
公开(公告)日：2009-10-20
申请号：US29321752
申请日：2008-07-23
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公开(公告)号：US20120004637A1
公开(公告)日：2012-01-05
申请号：US13203697
申请日：2010-01-27
申请人： Peter Krulevitch , Robert Wilk , Ulrich Kraft , Donna Savage , Nick Foley , James Glencross , David Shepherd , Zara Sieh , David Price
发明人： Peter Krulevitch , Robert Wilk , Ulrich Kraft , Donna Savage , Nick Foley , James Glencross , David Shepherd , Zara Sieh , David Price
CPC分类号： A61M5/315 , A61B5/002 , A61B5/14532 , A61M5/24 , A61M5/3129 , A61M5/3146 , A61M5/31525 , A61M5/31551 , A61M2005/3126 , A61M2005/3142 , A61M2205/14 , A61M2205/18 , A61M2205/215 , A61M2205/3317 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/52 , A61M2205/581 , A61M2205/583 , A61M2205/584 , A61M2205/6054 , A61M2205/6081 , A61M2205/8212 , A61M2209/04 , G01D5/1655 , G06F19/00 , G06F19/3468
摘要： Various embodiments of a “smart” drug delivery system are provided which includes an add-on module and a reusable or disposable drug pen in conjunction with a data management unit(s) DMU. Upon attachment to the pen, the add-on module may: determine dosage selected, injection of selected dosage, duration of injection, time of injection, whether the pen has been primed or shaken to thoroughly mix up insulin mixtures, transmit information relating to insulin dosage and injection to a data management unit, provide reminders, error warning or messages on improper usage or reuse of needles, track amount of drug remaining on board the pen or duration of usage of pen with respect to expiry of the drug on board, or provide an audible alarm for locating misplaced pen and module. Methods of using the drug delivery system are also described.
摘要翻译： 提供了“智能”药物递送系统的各种实施例，其包括与数据管理单元DMU结合的附加模块和可重复使用或一次性药物笔。 附加模块可以：确定所选择的剂量，所选剂量的注射，注射持续时间，注射时间，笔是否被引发或摇动以充分混合胰岛素混合物，传送与胰岛素相关的信息 剂量和注射到数据管理单元，提供提醒，错误警告或关于针的不正确使用或重复使用的信息，笔上留下的药物的轨迹量或笔的使用持续时间，关于药物到期的时间，或 提供用于定位放错的笔和模块的声音报警器。 还描述了使用药物递送系统的方法。
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公开(公告)号：US08556867B2
公开(公告)日：2013-10-15
申请号：US13203697
申请日：2010-01-27
申请人： Peter Krulevitch , Robert Wilk , Ulrich Kraft , Donna Savage , Nick Foley , James Glencross , David Shepherd , Zara Sieh , David Price
发明人： Peter Krulevitch , Robert Wilk , Ulrich Kraft , Donna Savage , Nick Foley , James Glencross , David Shepherd , Zara Sieh , David Price
CPC分类号： A61M5/315 , A61B5/002 , A61B5/14532 , A61M5/24 , A61M5/3129 , A61M5/3146 , A61M5/31525 , A61M5/31551 , A61M2005/3126 , A61M2005/3142 , A61M2205/14 , A61M2205/18 , A61M2205/215 , A61M2205/3317 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/52 , A61M2205/581 , A61M2205/583 , A61M2205/584 , A61M2205/6054 , A61M2205/6081 , A61M2205/8212 , A61M2209/04 , G01D5/1655 , G06F19/00 , G06F19/3468
摘要： Various embodiments of a “smart” drug delivery system are provided which includes an add-on module and a reusable or disposable drug pen in conjunction with a data management unit(s) DMU. Upon attachment to the pen, the add-on module may: determine dosage selected, injection of selected dosage, duration of injection, time of injection, whether the pen has been primed or shaken to thoroughly mix up insulin mixtures, transmit information relating to insulin dosage and injection to a data management unit, provide reminders, error warning or messages on improper usage or reuse of needles, track amount of drug remaining on board the pen or duration of usage of pen with respect to expiry of the drug on board, or provide an audible alarm for locating misplaced pen and module. Methods of using the drug delivery system are also described.
摘要翻译： 提供了“智能”药物递送系统的各种实施例，其包括与数据管理单元DMU结合的附加模块和可重复使用或一次性药物笔。 附加模块可以：确定所选择的剂量，所选剂量的注射，注射持续时间，注射时间，笔是否被引发或摇动以充分混合胰岛素混合物，传送与胰岛素相关的信息 剂量和注射到数据管理单元，提供提醒，错误警告或关于针的不正确使用或重复使用的信息，笔上留下的药物的轨迹量或笔的使用持续时间，关于药物到期的时间，或 提供用于定位放错的笔和模块的声音报警器。 还描述了使用药物递送系统的方法。
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公开(公告)号：US08556866B2
公开(公告)日：2013-10-15
申请号：US13203694
申请日：2010-01-27
申请人： Peter Krulevitch , Robert Wilk , Ulrich Kraft , Donna Savage , Nick Foley , James Glencross , David Shepherd , Zara Sieh
发明人： Peter Krulevitch , Robert Wilk , Ulrich Kraft , Donna Savage , Nick Foley , James Glencross , David Shepherd , Zara Sieh
CPC分类号： A61M5/315 , A61B5/002 , A61B5/14532 , A61M5/24 , A61M5/3129 , A61M5/3146 , A61M5/31525 , A61M5/31551 , A61M2005/3126 , A61M2005/3142 , A61M2205/14 , A61M2205/18 , A61M2205/215 , A61M2205/3317 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/52 , A61M2205/581 , A61M2205/583 , A61M2205/584 , A61M2205/6054 , A61M2205/6081 , A61M2205/8212 , A61M2209/04 , G01D5/1655 , G06F19/00 , G06F19/3468
摘要： Various embodiments of a “smart” drug delivery system are provided which includes an add-on module and a reusable or disposable drug pen. Upon attachment to the pen, the add-on module may: determine dosage selected, injection of selected dosage, duration of injection, time of injection, whether the pen has been primed or shaken to thoroughly mix up insulin mixtures, transmit information relating to insulin dosage and injection to a data management unit, provide reminders, error warning or messages on improper usage or reusage of needles, track amount of drug remaining on board the pen or duration of usage of pen with respect to expiry of the drug on board, or provide an audible alarm for locating misplaced pen and module.
摘要翻译： 提供了“智能”药物递送系统的各种实施例，其包括附加模块和可重复使用或一次性药物笔。 附加模块可以：确定所选择的剂量，所选剂量的注射，注射持续时间，注射时间，笔是否被引发或摇动以充分混合胰岛素混合物，传送与胰岛素相关的信息 剂量和注射到数据管理单元，提供提醒，错误警告或关于不正确使用或重复使用针头的信息，轨道上留下的药物量或笔的使用持续时间，以及在药物到期时的使用时间，或 提供用于定位放错的笔和模块的声音报警器。
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公开(公告)号：US20110313349A1
公开(公告)日：2011-12-22
申请号：US13203691
申请日：2010-01-27
申请人： Peter Krulevitch , Robert Wilk , Ulrich Kraft , Donna Savage , Nick Foley , James Glencross , David Shepherd , Zara Sieh
发明人： Peter Krulevitch , Robert Wilk , Ulrich Kraft , Donna Savage , Nick Foley , James Glencross , David Shepherd , Zara Sieh
IPC分类号： A61M5/31
CPC分类号： A61M5/315 , A61B5/002 , A61B5/14532 , A61M5/24 , A61M5/3129 , A61M5/3146 , A61M5/31525 , A61M5/31551 , A61M2005/3126 , A61M2005/3142 , A61M2205/14 , A61M2205/18 , A61M2205/215 , A61M2205/3317 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/52 , A61M2205/581 , A61M2205/583 , A61M2205/584 , A61M2205/6054 , A61M2205/6081 , A61M2205/8212 , A61M2209/04 , G01D5/1655 , G06F19/00 , G06F19/3468
摘要： Various embodiments of a medical module are provided which includes a primary module housing, a secondary module housing, a dosage sensor, a power source, and a microcontroller. The module is configured to be attached to a disposable drug delivery pen or a reusable drug delivery pen so that the module may: determine dosage selected, injection of selected dosage, duration of injection, time of injection, whether the pen has been primed or shaken to thoroughly mix up insulin mixtures, transmit information relating to insulin dosage and injection to a data management unit, provide reminders, error warning or messages on improper usage or reusage of needles, track amount of drug remaining on board the pen or duration of usage of pen with respect to expiry of the drug on board, or provide an audible alarm for locating misplaced pen and module.
摘要翻译： 提供了包括主模块外壳，次模块外壳，剂量传感器，电源和微控制器的医疗模块的各种实施例。 模块被配置为附接到一次性药物输送笔或可重复使用的药物递送笔，使得模块可以：确定所选择的剂量，所选剂量的注射，注射持续时间，注射时间，是否已经被注射或摇动 彻底混合胰岛素混合物，将与胰岛素剂量和注射相关的信息传输到数据管理单元，提供提醒，错误警告或关于不正当使用或重复使用针头的信息，跟踪笔上留下的药物量或使用持续时间 关于药物到期的笔，或提供用于定位放错的笔和模块的声音报警器。
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公开(公告)号：US08556865B2
公开(公告)日：2013-10-15
申请号：US13203691
申请日：2010-01-27
申请人： Peter Krulevitch , Robert Wilk , Ulrich Kraft , Donna Savage , Nick Foley , James Glencross , David Shepherd , Zara Sieh
发明人： Peter Krulevitch , Robert Wilk , Ulrich Kraft , Donna Savage , Nick Foley , James Glencross , David Shepherd , Zara Sieh
CPC分类号： A61M5/315 , A61B5/002 , A61B5/14532 , A61M5/24 , A61M5/3129 , A61M5/3146 , A61M5/31525 , A61M5/31551 , A61M2005/3126 , A61M2005/3142 , A61M2205/14 , A61M2205/18 , A61M2205/215 , A61M2205/3317 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/52 , A61M2205/581 , A61M2205/583 , A61M2205/584 , A61M2205/6054 , A61M2205/6081 , A61M2205/8212 , A61M2209/04 , G01D5/1655 , G06F19/00 , G06F19/3468
摘要： Various embodiments of a medical module are provided which includes a primary module housing, a secondary module housing, a dosage sensor, a power source, and a microcontroller. The module is configured to be attached to a disposable drug delivery pen or a reusable drug delivery pen so that the module may: determine dosage selected, injection of selected dosage, duration of injection, time of injection, whether the pen has been primed or shaken to thoroughly mix up insulin mixtures, transmit information relating to insulin dosage and injection to a data management unit, provide reminders, error warning or messages on improper usage or reusage of needles, track amount of drug remaining on board the pen or duration of usage of pen with respect to expiry of the drug on board, or provide an audible alarm for locating misplaced pen and module.
摘要翻译： 提供了包括主模块外壳，次模块外壳，剂量传感器，电源和微控制器的医疗模块的各种实施例。 模块被配置为附接到一次性药物输送笔或可重复使用的药物递送笔，使得模块可以：确定所选择的剂量，所选剂量的注射，注射持续时间，注射时间，是否已经被注射或摇动 彻底混合胰岛素混合物，将与胰岛素剂量和注射相关的信息传输到数据管理单元，提供提醒，错误警告或关于不正当使用或重复使用针头的信息，跟踪笔上留下的药物量或使用持续时间 关于药物到期的笔，或提供用于定位放错的笔和模块的声音报警器。
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公开(公告)号：US20110313350A1
公开(公告)日：2011-12-22
申请号：US13203694
申请日：2010-01-27
申请人： Peter Krulevitch , Robert Wilk , Ulrich Kraft , Donna Savage , Nick Foley , James Glencross , David Shepherd , Zara Sieh
发明人： Peter Krulevitch , Robert Wilk , Ulrich Kraft , Donna Savage , Nick Foley , James Glencross , David Shepherd , Zara Sieh
IPC分类号： A61M5/315
CPC分类号： A61M5/315 , A61B5/002 , A61B5/14532 , A61M5/24 , A61M5/3129 , A61M5/3146 , A61M5/31525 , A61M5/31551 , A61M2005/3126 , A61M2005/3142 , A61M2205/14 , A61M2205/18 , A61M2205/215 , A61M2205/3317 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/52 , A61M2205/581 , A61M2205/583 , A61M2205/584 , A61M2205/6054 , A61M2205/6081 , A61M2205/8212 , A61M2209/04 , G01D5/1655 , G06F19/00 , G06F19/3468
摘要： Various embodiments of a “smart” drug delivery system are provided which includes an add-on module and a reusable or disposable drug pen. Upon attachment to the pen, the add-on module may: determine dosage selected, injection of selected dosage, duration of injection, time of injection, whether the pen has been primed or shaken to thoroughly mix up insulin mixtures, transmit information relating to insulin dosage and injection to a data management unit, provide reminders, error warning or messages on improper usage or reusage of needles, track amount of drug remaining on board the pen or duration of usage of pen with respect to expiry of the drug on board, or provide an audible alarm for locating misplaced pen and module.
摘要翻译： 提供了“智能”药物递送系统的各种实施例，其包括附加模块和可重复使用或一次性药物笔。 附加模块可以：确定所选择的剂量，所选剂量的注射，注射持续时间，注射时间，笔是否被引发或摇动以充分混合胰岛素混合物，传送与胰岛素相关的信息 剂量和注射到数据管理单元，提供提醒，错误警告或关于不正确使用或重复使用针头的信息，轨道上留下的药物量或笔的使用持续时间，以及在药物到期时的使用时间，或 提供用于定位放错的笔和模块的声音报警器。
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公开(公告)号：US09724475B2
公开(公告)日：2017-08-08
申请号：US13203707
申请日：2010-01-27
申请人： Peter Krulevitch , Ulrich Kraft , Robert Wilk , Zara Sieh , Mitch Zhao
发明人： Peter Krulevitch , Ulrich Kraft , Robert Wilk , Zara Sieh , Mitch Zhao
CPC分类号： A61M5/315 , A61B5/002 , A61B5/14532 , A61M5/24 , A61M5/3129 , A61M5/3146 , A61M5/31525 , A61M5/31551 , A61M2005/3126 , A61M2005/3142 , A61M2205/14 , A61M2205/18 , A61M2205/215 , A61M2205/3317 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/52 , A61M2205/581 , A61M2205/583 , A61M2205/584 , A61M2205/6054 , A61M2205/6081 , A61M2205/8212 , A61M2209/04 , G01D5/1655 , G06F19/00 , G06F19/3468
摘要： Various embodiments of a “smart” drug delivery pen are provided which include a drug delivery pen having an inertial sensor or accelerometer. A system is also provided that includes the smart drug pen in conjunction with a data management unit(s) DMU. Various exemplary methods for use of the pens and systems are also described and illustrated.
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公开(公告)号：US07666287B2
公开(公告)日：2010-02-23
申请号：US11614517
申请日：2006-12-21
申请人： Mingqi Zhao , Mark Huang , Stan Thomas , Peter Krulevitch
发明人： Mingqi Zhao , Mark Huang , Stan Thomas , Peter Krulevitch
IPC分类号： G01N27/27
CPC分类号： F04B17/00 , B29C45/14778 , B29C47/0021 , B29C47/065 , B29C47/067 , B29C70/685 , B29K2023/06 , B29K2023/083 , B29K2023/12 , B29K2025/00 , B29K2027/16 , B29K2031/04 , B29K2067/00 , B29K2075/00 , B29K2077/00 , B29K2079/085 , B29K2081/06 , B29L2031/755 , F04B19/006 , Y10T29/49236 , Y10T137/206 , Y10T156/10 , Y10T156/1039 , Y10T156/1052 , Y10T156/1092
摘要： A method for preparing an electrokinetic element is provided and generally includes providing a porous membrane adapted for use in an electrokinetic pump and encapsulating the porous membrane within a polymer substrate to yield an electrokinetic element base member having the porous membrane encapsulated by the polymer. In one embodiment, the method can include laminating the porous membrane between opposed sheets of a polymer before the step of encapsulating. The method can also include cutting the electrokinetic element base member into a plurality of slices and assembling an electrokinetic infusion pump by inserting a slice into a chamber of the pump.
摘要翻译： 提供了一种制备电动元件的方法，并且通常包括提供适用于电动泵中的多孔膜并将多孔膜封装在聚合物基底内以产生具有被聚合物包封的多孔膜的电动元件基底构件。 在一个实施方案中，该方法可以包括在封装步骤之前将多孔膜层叠在聚合物的相对片之间。 该方法还可以包括将动电元件基底部件切割成多个切片，并通过将切片插入泵的腔室来组装电动输注泵。
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公开(公告)号：US20090112185A1
公开(公告)日：2009-04-30
申请号：US12261450
申请日：2008-10-30
申请人： Peter Krulevitch , Frank Cichocki , Lorin P. Olson
发明人： Peter Krulevitch , Frank Cichocki , Lorin P. Olson
IPC分类号： A61M25/00
CPC分类号： A61M5/158 , A61M5/3286 , A61M5/3287 , A61M5/329 , A61M25/00 , A61M25/0068 , A61M2005/1585 , A61M2005/1587 , A61M2205/0266
摘要： A medical device includes a medical device flexible conduit that has an elongated Nitinol strip with a distal end, a proximal end, a longitudinal axis running from the distal end to the proximal end, a sharp head extending from the distal end, and a channel etched therein. Moreover, the channel is dispositioned along the longitudinal axis. The medical device flexible conduit also has a flexible tube at least partially jacketing the elongated Nitinol strip between the distal end and the proximal end, with the channel and the flexible tube defining a conduit. The medical device also includes an insertion mechanism configured to insert a portion of the flexible conduit, including the sharp head, into a user's target site such that the conduit provides fluid communication to the target site.
摘要翻译： 医疗装置包括医疗装置柔性导管，其具有细长的镍钛诺带，其具有远端，近端，从远端延伸到近端的纵向轴线，从远端延伸的尖头，以及蚀刻的通道 其中。 此外，通道沿着纵向轴线布置。 医疗器械柔性导管还具有柔性管，其至少部分地将细长的镍钛诺带夹在远端和近端之间，通道和柔性管限定导管。 该医疗装置还包括插入机构，该插入机构构造成将包括尖头的柔性导管的一部分插入使用者的目标部位，使得导管向目标部位提供流体连通。
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