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17 条记录 (耗时 0.029 秒)

    Salt of 1,3,5-triazine-2,4,6-triamine derivative
    4.
    发明授权
    Salt of 1,3,5-triazine-2,4,6-triamine derivative 失效
    1,3,5-三嗪-2,4,6-三胺衍生物的盐

    公开(公告)号：US08399663B2

    公开(公告)日：2013-03-19

    申请号：US12753415

    申请日：2010-04-02

    申请人： Junya Ohmori ,  Makoto Kasai ,  Takenori Kimura ,  Noritaka Hamada ,  Ryo Mizoguchi ,  Satoshi Miyamoto ,  Noriyuki Kawano

    发明人： Junya Ohmori ,  Makoto Kasai ,  Takenori Kimura ,  Noritaka Hamada ,  Ryo Mizoguchi ,  Satoshi Miyamoto ,  Noriyuki Kawano

    IPC分类号： C07D403/12 ,  A61K31/53 ,  A61P25/28

    CPC分类号： A61K31/53 ,  C07D403/12

    摘要： Anytime obtained is uniform crystal of N-(4-fluorophenyl)-N′-phenyl-N″-(pyrimidin-2-ylmethyl)-1,3,5-triazine-2,4,6-triamine (compound A) and/or N,N′-bis (4-fluorophenyl)-N″-(pyrimidin-2-ylmethyl)-1,3,5-triazine-2,4,6-triamine (compound B) as a medicament or a starting material for the preparation of the medicament, and provided are a fumarate of the compound A and/or the compound B having excellent stability and a novel crystal thereof. A salt of the compound A and/or the compound B with fumaric acid enables uniform crystal to be anytime obtained, and thus, it is a compound that is very useful as a medicament or a starting material for the preparation of the medicament having excellent stability.

    摘要翻译： 得到的N-（4-氟苯基）-N'-苯基-N“ - （嘧啶-2-基甲基）-1,3,5-三嗪-2,4,6-三胺（化合物A）和 /或N，N'-二（4-氟苯基）-N“ - （嘧啶-2-基甲基）-1,3,5-三嗪-2,4,6-三胺（化合物B）作为药物或起始物 用于制备药物的材料，并且提供具有优异的稳定性和新颖结晶的化合物A和/或化合物B的富马酸盐。 化合物A和/或化合物B与富马酸的盐能够随时获得均匀的结晶，因此，作为制备具有优异稳定性的药物的药物或原料非常有用的化合物 。

    Thiophene derivative and pharmaceutical composition thereof
    6.
    发明授权
    Thiophene derivative and pharmaceutical composition thereof 失效
    噻吩衍生物及其药物组合物

    公开(公告)号：US6090804A

    公开(公告)日：2000-07-18

    申请号：US214228

    申请日：1998-12-30

    申请人： Takenori Kimura ,  Takeshi Murakami ,  Junya Ohmori ,  Takuma Morita ,  Shin-ichi Tsukamoto

    发明人： Takenori Kimura ,  Takeshi Murakami ,  Junya Ohmori ,  Takuma Morita ,  Shin-ichi Tsukamoto

    IPC分类号： A61K31/4245 ,  C07D333/24 ,  C07D409/04 ,  C07D409/06 ,  C07D409/14 ,  C07D413/04 ,  C07D413/14 ,  C07D417/04 ,  C07D471/04 ,  C07D487/04 ,  C07D521/00 ,  A61K31/55 ,  C07D403/00 ,  C07D405/00

    CPC分类号： C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D333/24 ,  C07D409/04 ,  C07D409/14 ,  C07D413/04 ,  C07D413/14 ,  C07D417/04 ,  C07D471/04 ,  C07D487/04

    摘要： Thiophene derivatives represented by the following general formula (I) or pharmaceutically acceptable salts thereof. Said compounds act as an anti-PCP agonist and therefore are useful as psychotropic or antischizophrenic agents and so on. ##STR1## (In the above formula, R.sub.1 is a formula --A.sub.1 --X.sub.1 --R.sub.3 ; R.sub.2 is a formula --A.sub.2 --X.sub.2 --R.sub.4 or does not exist; B ring is a 7- to 10-membered nitrogen-containing cycloalkyl ring; Ar ring is an aryl or heteroaryl ring; A.sub.1, A.sub.2 and A.sub.3 may be the same or different from one another and each represents a bond or a lower alkylene group; X.sub.1 and X.sub.2 may be the same or different from each other and each represents a bond or a formula --O--, --S--or the like; R.sub.3 and R.sub.4 may be the same or different from each other and each represents a hydrogen atom, a cyclic imido group or a lower alkyl group, a cycloalkyl group, an aryl group or an aralkyl group; with the proviso that, when Ar ring is thiazole ring, either one of A.sub.1 and A.sub.2 is a lower alkylene group. Also, when Ar ring is a benzene ring, a case in which one of R.sub.1 and R.sub.2 is methyl group or a halogen group and the other is a hydrogen atom is excluded.)

    摘要翻译： PCT No.PCT / JP97 / 02255 Sec。 371日期1998年12月30日第 102（e）1998年12月30日日期PCT 1997年6月30日PCT公布。 公开号WO98 / 00420 日期1998年1月8日由以下通式（I）表示的噻吩衍生物或其药学上可接受的盐。 所述化合物作为抗PCP激动剂，因此可用作精神药物或抗精神分裂药物等。 （在上式中，R 1为式-A 1 -X 1 -R 3; R 2为式-A 2 -X 2 -R 4或不存在; B环为7至10元含氮环烷基环; Ar环 是芳基或杂芳基环; A 1，A 2和A 3可以彼此相同或不同，并且各自表示键或低级亚烷基; X 1和X 2可以彼此相同或不同，并且各自表示键或 式-O-，-S-等; R 3和R 4可以相同或不同，表示氢原子，环状亚氨基或低级烷基，环烷基，芳基或 芳烷基;条件是当Ar环是噻唑环时，A1和A2中的任一个是低级亚烷基，当Ar环是苯环时，其中R1和R2之一是甲基 或卤素基团，另一个为氢原子。）

    Prismatic secondary battery
    7.
    发明授权
    Prismatic secondary battery 有权
    棱镜二次电池

    公开(公告)号：US09406921B2

    公开(公告)日：2016-08-02

    申请号：US13880765

    申请日：2011-10-28

    申请人： Takayuki Hattori ,  Takenori Kimura ,  Yasuhiro Yamauchi ,  Toshiyuki Nohma

    发明人： Takayuki Hattori ,  Takenori Kimura ,  Yasuhiro Yamauchi ,  Toshiyuki Nohma

    IPC分类号： H01M2/26 ,  H01M2/02

    CPC分类号： H01M2/26 ,  H01M2/0217 ,  H01M2/263 ,  H01M2/266

    摘要： A prismatic secondary battery is provided with a negative/positive electrode collector (18), which are disposed on either one of a wound negative/positive electrode substrate exposed portion (15), and a negative/positive electrode collector receiving member (19) which is disposed on another surface. At least one of the negative/positive electrode collector has a recess portion (30) formed in part on a surface on the side not facing the negative/positive electrode substrate exposed portions so as to be thinner than the thickness of the other portion. Resistance welding is carried out in this recessed part, thereby a large welding nugget is formed between the negative/positive electrode exposed portion and the negative/positive electrode collector.

    摘要翻译： 棱镜二次电池设置有负极/正极集电体（18），其设置在卷绕的负极/正极基板露出部分（15）和负极/正极集电体接收部件（19）中的任一个上，负极/正极集电体接收部件 被布置在另一个表面上。 负极/正极集电体中的至少一个具有凹部（30），该凹部（30）部分地形成在不面向负极/正极基板露出部分的一侧的表面上，以便比另一部分的厚度薄。 在该凹部进行电阻焊接，在负极/正极露出部和负极/正极集电体之间形成大的焊接熔核。

    Prismatic sealed secondary battery
    8.
    发明授权
    Prismatic sealed secondary battery 有权
    Prismatic密封二次电池

    公开(公告)号：US08460811B2

    公开(公告)日：2013-06-11

    申请号：US13218697

    申请日：2011-08-26

    申请人： Takayuki Hattori ,  Takenori Kimura ,  Yasuhiro Yamauchi ,  Toshiyuki Nohma

    发明人： Takayuki Hattori ,  Takenori Kimura ,  Yasuhiro Yamauchi ,  Toshiyuki Nohma

    IPC分类号： H01M10/36

    CPC分类号： H01M2/0217 ,  H01M2/263 ,  H01M2/266 ,  H01M10/049

    摘要： In a prismatic sealed secondary battery according to an embodiment of the present invention, at least one of positive electrode substrate exposed portions and negative electrode substrate exposed portions of an electrode assembly is split into two groups, and therebetween are disposed intermediate members that are made of a resin material and hold one or more connecting conductive members. The two split substrate exposed portions are electrically connected to collector members and to at least one of the connecting conductive members by resistance-welding. Voids are formed in resin material portions of the intermediate members that are located around the resistance-welded portions of the connecting conductive members. Therefore, lowered resistance between the substrate exposed portions and the collector members and stabilized quality of the welds are realized and the manufacturing yield of the prismatic sealed secondary battery is improved.

    摘要翻译： 在根据本发明实施例的方形密封二次电池中，电极组件的正极基板暴露部分和负电极基板暴露部分中的至少一个被分成两组，它们之间设置有中间部件， 树脂材料并且保持一个或多个连接导电构件。 两个分离的衬底暴露部分通过电阻焊接电连接到集电器构件和至少一个连接导电构件。 在位于连接导电构件的电阻焊接部分周围的中间构件的树脂材料部分中形成有空隙。 因此，实现了基板暴露部分与集电体之间的电阻降低，并且焊接质量稳定，提高了棱柱密封二次电池的制造成品率。

    PRISMATIC SEALED SECONDARY BATTERY
    9.
    发明申请
    PRISMATIC SEALED SECONDARY BATTERY 有权
    专用密封二次电池

    公开(公告)号：US20120028088A1

    公开(公告)日：2012-02-02

    申请号：US13192292

    申请日：2011-07-27

    申请人： Takayuki Hattori ,  Takenori Kimura ,  Yasuhiro Yamauchi ,  Toshiyuki Nohma

    发明人： Takayuki Hattori ,  Takenori Kimura ,  Yasuhiro Yamauchi ,  Toshiyuki Nohma

    IPC分类号： H01M10/36 ,  H01M2/12 ,  H01M2/26

    CPC分类号： H01M2/024 ,  H01M2/0217 ,  H01M2/263 ,  H01M2/30

    摘要： The positive electrode substrate exposed portions or the negative electrode substrate exposed portions, or both, of an electrode assembly is split into two groups, and therebetween is disposed an intermediate member made of a resin material and holding one or more connecting conductive members. Collector members for the substrate exposed portions split into two groups is electrically joined by a resistance welding method to the substrate exposed portions split into two groups, together with the connecting conductive member(s) of the intermediate member. The resin material portion of the intermediate member protrudes, in the extension direction of the substrate exposed portions split into two groups, beyond the ends of the substrate exposed portions split into two groups and the ends of the collector member to a prismatic outer can. This structure enables enhanced resistance between the substrate exposed portions and the collector member and curbs variation in the welding strength.

    摘要翻译： 电极组件的正极基板暴露部分或负电极基板暴露部分或两者被分成两组，并且在它们之间设置由树脂材料制成并保持一个或多个连接导电部件的中间部件。 通过电阻焊接方法将基板暴露部分分成两组的集电体部件与中间部件的连接导电部件一起被分成两组的基板暴露部分。 中间构件的树脂材料部分在基板暴露部分的分成两组的延伸方向上突出超过分成两组的基板暴露部分的端部和集电体构件的端部到棱柱形外罐。 这种结构使得能够增强基板暴露部分和集电体部件之间的电阻，并且限制焊接强度的变化。