公开(公告)号：US08283337B2

公开(公告)日：2012-10-09

申请号：US12528116

申请日：2008-02-22

申请人： Nobuo Sasaki ,  Yuichi Tei ,  Ryosuke Echigo ,  Shigeki Suzuki ,  Touru Hakukawa

发明人： Nobuo Sasaki ,  Yuichi Tei ,  Ryosuke Echigo ,  Shigeki Suzuki ,  Touru Hakukawa

IPC分类号： A01N43/04 ,  A61K31/715 ,  C13K5/00 ,  C13K7/00

CPC分类号： A61K31/7016

摘要： An object of the present invention is to provide an agent for treating or preventing vasospasm. An object of the present invention is to provide an agent for treating or preventing cerebral vasospasm as well as arterial vasospasm. Further, an object of the present invention is to provide an agent for treating or preventing cerebral ischemia and cerebral infarction.The above problems are solved by an agent for treating and preventing vasospasm, cerebral ischemia, or cerebral infarction, comprising trehalose as the active ingredient. It is possible, by using such a trehalose-comprising agent, to suppress phenomena such as contraction of blood vessel and thickening of tunica intima and tunica media and to prevent or treat vasospasm and vasospasm-dependent diseases.

摘要翻译： 本发明的目的在于提供治疗或预防血管痉挛的药剂。 本发明的目的是提供治疗或预防脑血管痉挛以及动脉血管痉挛的药剂。 此外，本发明的目的是提供治疗或预防脑缺血和脑梗死的药剂。 上述问题由包含海藻糖作为活性成分的治疗和预防血管痉挛，脑缺血或脑梗死的药物解决。 通过使用这样的含海藻糖的试剂可以抑制血管收缩等现象，并且可以抑制内膜和中膜介质的增厚以及预防或治疗血管痉挛和血管痉挛依赖性疾病。

公开(公告)号：US20100035837A1

公开(公告)日：2010-02-11

申请号：US12528116

申请日：2008-02-22

申请人： Nobuo Sasaki ,  Yuichi Tei ,  Ryosuke Echigo ,  Shigeki Suzuki ,  Touru Hakukawa

发明人： Nobuo Sasaki ,  Yuichi Tei ,  Ryosuke Echigo ,  Shigeki Suzuki ,  Touru Hakukawa

IPC分类号： A61K31/7016 ,  C13K13/00

CPC分类号： A61K31/7016

摘要： An object of the present invention is to provide an agent for treating or preventing vasospasm. An object of the present invention is to provide an agent for treating or preventing cerebral vasospasm as well as arterial vasospasm. Further, an object of the present invention is to provide an agent for treating or preventing cerebral ischemia and cerebral infarction.The above problems are solved by an agent for treating and preventing vasospasm, cerebral ischemia, or cerebral infarction, comprising trehalose as the active ingredient. It is possible, by using such a trehalose-comprising agent, to suppress phenomena such as contraction of blood vessel and thickening of tunica intima and tunica media and to prevent or treat vasospasm and vasospasm-dependent diseases.

摘要翻译： 本发明的目的在于提供治疗或预防血管痉挛的药剂。 本发明的目的是提供治疗或预防脑血管痉挛以及动脉血管痉挛的药剂。 此外，本发明的目的是提供治疗或预防脑缺血和脑梗死的药剂。 上述问题由包含海藻糖作为活性成分的治疗和预防血管痉挛，脑缺血或脑梗死的药物解决。 通过使用这样的含海藻糖的试剂可以抑制血管收缩等现象，并且可以抑制内膜和中膜介质的增厚以及预防或治疗血管痉挛和血管痉挛依赖性疾病。