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公开(公告)号:US10829553B2
公开(公告)日:2020-11-10
申请号:US15581079
申请日:2017-04-28
发明人: Stefano V. Gulla , Christine Huard , Janet Elizabeth Buhlmann , Juan Carlos Almagro , Sreekumar R. Kodangattil , Steven A. Greenberg , Edward Roland Lavallie , Eric M. Bennett , Lidia Mosyak , James Perry Hall , Anthony John Coyle
摘要: The invention relates to antibodies, or antigen-binding fragments thereof, that specifically binds to interferon beta (IFNβ). Such antibodies, or antigen-binding fragments thereof, are useful for various therapeutic or diagnostic purposes.
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公开(公告)号:US20210163588A1
公开(公告)日:2021-06-03
申请号:US17092998
申请日:2020-11-09
发明人: Stefano V. Gulla , Christine Huard , Janet Elizabeth Buhlmann , Juan Carlos Almagro , Sreekumar R. Kodangattil , Steven A. Greenberg , Edward Roland Lavallie , Eric M. Bennett , Lidia Mosyak , James Perry Hall , Anthony John Coyle
IPC分类号: C07K16/24
摘要: The invention relates to antibodies, or antigen-binding fragments thereof, that specifically binds to interferon beta (IFNβ). Such antibodies, or antigen-binding fragments thereof, are are useful for various therapeutic or diagnostic purposes.
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公开(公告)号:US20170313769A1
公开(公告)日:2017-11-02
申请号:US15581079
申请日:2017-04-28
发明人: Stefano V. Gulla , Christine Huard , Janet Elizabeth Buhlmann , Juan Carlos Almagro , Sreekumar R. Kodangattil , Steven A. Greenberg , Edward Roland Lavallie , Eric M. Bennett , Lidia Mosyak , James Perry Hall , Anthony John Coyle
IPC分类号: C07K16/24
摘要: The invention relates to antibodies, or antigen-binding fragments thereof, that specifically binds to interferon beta (IFNβ). Such antibodies, or antigen-binding fragments thereof, are useful for various therapeutic or diagnostic purposes.
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公开(公告)号:US20200157212A1
公开(公告)日:2020-05-21
申请号:US16614701
申请日:2018-06-08
发明人: Stephen Berasi , Janet Elizabeth Buhlmann , Eric M. Bennett , Nathan Higginson-Scott , Huilan Gao , Zong Sean Juo , Stefano V. Gulla , Christine Huard , Sreekumar R. Kodangattil , Jian Li , Weining Lu , Xueping Fan , David J. Salant
摘要: The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to ROBO2, as well as uses, and methods thereof.
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公开(公告)号:US11365253B2
公开(公告)日:2022-06-21
申请号:US16614701
申请日:2018-06-08
发明人: Stephen Berasi , Janet Elizabeth Buhlmann , Eric M. Bennett , Nathan Higginson-Scott , Huilan Gao , Zong Sean Juo , Stefano V. Gulla , Christine Huard , Sreekumar R. Kodangattil , Jian Li , Weining Lu , Xueping Fan , David J. Salant
IPC分类号: C07H21/04 , C12P21/06 , C12N15/87 , C12N1/20 , C12N15/74 , A61K39/00 , A61K39/395 , C07K16/00 , C07K16/28 , A61P13/12 , C12N15/85
摘要: The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to ROBO2, as well as uses, and methods thereof.
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公开(公告)号:US20210214414A1
公开(公告)日:2021-07-15
申请号:US17125903
申请日:2020-12-17
发明人: Stephen Berasi , Janet Elizabeth Buhlmann , Nathan Higginson-Scott , Michael Shamashkin , Matthew Russo , Stefano V. Gulla , Zong Sean Juo , Sreekumar R. Kodangattil , Weining Lu , Xueping Fan , David J. Salant
IPC分类号: C07K14/705 , C12N15/11 , C12N15/52 , C12N15/09 , C07K19/00 , C12N15/63 , C07H21/04 , A61K38/17 , A61P13/12
摘要: The invention provides recombinant Roundabout Receptor 2 (ROBO2) proteins designed to bind SLIT ligands and prevent their binding to ROBO2 cell surface receptors. Also provided are methods for use of these recombinant ROBO2 proteins.
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公开(公告)号:US10906955B2
公开(公告)日:2021-02-02
申请号:US15995286
申请日:2018-06-01
发明人: Stephen Berasi , Janet Elizabeth Buhlmann , Nathan Higginson-Scott , Michael Shamashkin , Matthew Russo , Stefano V. Gulla , Zong Sean Juo , Sreekumar R. Kodangattil , Weining Lu , Xueping Fan , David J. Salant
IPC分类号: C07K14/705 , C07K19/00 , C12N15/09 , C12N15/11 , C12N15/52 , C12N15/63 , C07H21/04 , A61P13/12 , A61K38/17 , A61K38/00
摘要: The invention provides recombinant Roundabout Receptor 2 (ROBO2) proteins designed to bind SLIT ligands and prevent their binding to ROBO2 cell surface receptors. Also provided are methods for use of these recombinant ROBO2 proteins.
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公开(公告)号:US20180346542A1
公开(公告)日:2018-12-06
申请号:US15995286
申请日:2018-06-01
发明人: Stephen Berasi , Janet Elizabeth Buhlmann , Nathan Higginson-Scott , Michael Shamashkin , Matthew Russo , Stefano V. Gulla , Zong Sean Juo , Sreekumar R. Kodangattil , Weining Lu , Xueping Fan , David J. Salant
IPC分类号: C07K14/705 , A61P13/12
CPC分类号: C07K14/70503 , A61K38/00 , C07K2319/30
摘要: The invention provides recombinant Roundabout Receptor 2 (ROBO2) proteins designed to bind SLIT ligands and prevent their binding to ROBO2 cell surface receptors. Also provided are methods for use of these recombinant ROBO2 proteins.
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