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公开(公告)号：US10457957B2
公开(公告)日：2019-10-29
申请号：US15840073
申请日：2017-12-13
发明人： Andre R Abad , Zhenglin Hou , Lu Liu , Brad Poland , Ute Schellenberger , Ingrid Udranszky , Jimei Wang , Jun-Zhi Wei , Thomas C Wolfe , Weiping Xie , Lan Zhou , Genhai Zhu
IPC分类号： C12N15/82 , A01N63/02 , C07K14/325 , A01N37/46
摘要： Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are isolated insecticidal proteins and nucleic acids. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.
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2.发明授权公开(公告)号：US11008371B2
公开(公告)日：2021-05-18
申请号：US16342343
申请日：2017-09-25
发明人： Andre Roger Abad , Andrew Carl Crow , Brad Poland , Jimei Wang
IPC分类号： C07K14/325 , C12N15/82 , A01N63/23
摘要： The disclosure provides nucleic acids, and variants and fragments thereof, obtained from strains of Bacillus thuringiensis encoding polypeptides having pesticidal activity against insect pests, including Lepidoptera. Particular embodiments of the disclosure provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.
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公开(公告)号：US10480008B2
公开(公告)日：2019-11-19
申请号：US15518721
申请日：2015-10-09
发明人： Andre R. Abad , Andrew C. Crow , Brad Poland , Xiaomei Shi , Thomas C. Wolfe
摘要： The invention provides nucleic acids, and variants and fragments thereof, obtained from strains of Bacillus thuringiensis encoding polypeptides having pesticidal activity against insect pests, including Lepidoptera and Coleoptera. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.
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公开(公告)号：US11008585B2
公开(公告)日：2021-05-18
申请号：US16098452
申请日：2017-05-02
发明人： Jennifer Kara Barry , Christian Bartholomay , Louisa D'Lima , James J. English , Kevin Robert Hayes , Lu Liu , Amy Lum , Brad Poland , Eric Jude Schepers , Weiping Xie , Nasser Yalpani , Genhai Zhu
摘要： Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.
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公开(公告)号：US09879277B2
公开(公告)日：2018-01-30
申请号：US14775344
申请日：2014-03-13
发明人： Andre R. Abad , Zhenglin Hou , Lu Liu , Brad Poland , Ute Schellenberger , Ingrid Udranszky , Jimei Wang , Jun-Zhi Wei , Thomas C. Wolfe , Weiping Xie , Lan Zhou , Genhai Zhu
CPC分类号： C12N15/8286 , A01N37/18 , A01N37/46 , A01N63/02 , C07K14/32 , C07K14/325 , Y02A40/162
摘要： Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are isolated insecticidal proteins and nucleic acids. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.
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公开(公告)号：US11492639B2
公开(公告)日：2022-11-08
申请号：US16771816
申请日：2018-11-14
发明人： Andre R Abad , Hua Dong , Sue B Lo , Brad Poland , Xiaomei Shi , Jimei Wang , Thomas Chad Wolfe , Lan Zhou
IPC分类号： C12N15/82 , C07K14/325
摘要： The disclosure provides nucleic acids, and variants and fragments thereof, obtained from strains of Bacillus thuringiensis encoding polypeptides having pesticidal activity against insect pests, including Lepidopteran and Coleopteran. Particular embodiments of the disclosure provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.
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公开(公告)号：US20180094278A1
公开(公告)日：2018-04-05
申请号：US15840073
申请日：2017-12-13
发明人： Andre R Abad , Zhenglin Hou , Lu Liu , Brad Poland , Ute Schellenberger , Ingrid Udranszky , Jimei Wang , Jun-Zhi Wei , Thomas C Wolfe , Weiping Xie , Lan Zhou , Genhai Zhu
CPC分类号： C12N15/8286 , A01N37/46 , A01N63/02 , C07K14/325 , Y02A40/162
摘要： Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are isolated insecticidal proteins and nucleic acids. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.
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公开(公告)号：US11208440B2
公开(公告)日：2021-12-28
申请号：US15557384
申请日：2016-03-03
发明人： Lu Liu , Jarred Kenneth Oral , Brad Poland , Ute Schellenberger
摘要： Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity. Structure based methods for engineering insecticidal proteins of the disclosure to have modified physical properties are provided.
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