MINOCYCLINE COMPOUNDS AND METHODS OF USE THEREOF
    4.
    发明申请
    MINOCYCLINE COMPOUNDS AND METHODS OF USE THEREOF 有权
    咪喹啉化合物及其使用方法

    公开(公告)号:US20150087711A1

    公开(公告)日:2015-03-26

    申请号:US14258847

    申请日:2014-04-22

    IPC分类号: A61K31/165

    CPC分类号: A61K31/65 A61K31/165

    摘要: Methods and compositions for using a tetracycline compound to treat bacterial infections are described. In one embodiment, for example, the invention provides a method of treating a subject for an infection, comprising administering to said subject an effective amount of 9-[(2,2-dimethyl-propyl amino)-methyl]-minocycline or a salt thereof, such that said subject is treated, wherein said infection is selected from the group consisting of MSSA, MRSA, B-streptococci, Viridans Streptococci, Enterococcus, or combinations thereof.

    摘要翻译: 描述了使用四环素化合物治疗细菌感染的方法和组合物。 在一个实施方案中,例如,本发明提供了治疗受试者感染的方法,包括向所述受试者施用有效量的9 - [(2,2-二甲基 - 丙基氨基) - 甲基]米诺环素或盐 使得所述受试者被治疗,其中所述感染选自MSSA,MRSA,B-链球菌,Viridans链球菌,肠球菌或其组合。