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    Dual Valve Prosthesis for Transcatheter Valve Implantation
    3.
    发明申请
    Dual Valve Prosthesis for Transcatheter Valve Implantation 有权
    用于经导管瓣植入的双瓣假体

    公开(公告)号：US20130261737A1

    公开(公告)日：2013-10-03

    申请号：US13432497

    申请日：2012-03-28

    申请人： Declan Costello

    发明人： Declan Costello

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2418 ,  A61F2/2436 ,  A61F2230/0054

    摘要： A dual valve prosthesis having first and second prosthetic valve sections is disclosed. The first prosthetic valve section includes a stent structure with a first prosthetic valve secured therein and the second prosthetic valve section includes an annular frame with a second prosthetic valve secured therein. When the dual valve prosthesis is in an expanded configuration, the annular frame extends from the stent structure such that the first and second prosthetic valves are laterally offset from each other. In a method in accordance herewith, the first and second prosthetic valve sections include prosthetic aortic and mitral valves, respectively, and the dual heart valve prosthesis is configured to replace both the native aortic and mitral valves of the heart in a single transcatheter heart valve implantation procedure.

    摘要翻译： 公开了一种具有第一和第二假体瓣膜部分的双瓣膜假体。 第一假体瓣膜部分包括具有固定在其中的第一假体瓣膜的支架结构，第二假体瓣膜部分包括固定在其中的第二假体瓣膜的环形框架。 当双瓣膜假体处于膨胀构型时，环形框架从支架结构延伸，使得第一和第二假体瓣彼此横向偏移。 在根据本发明的方法中，第一和第二假体瓣膜部分分别包括假体主动脉和二尖瓣，并且双心脏瓣膜假体构造成在单个经导管心脏瓣膜植入中替换心脏的天然主动脉瓣和二尖瓣 程序。

    Valve Introducers With Adjustable Deployment Mechanism and Implantation Depth Gauge
    5.
    发明申请
    Valve Introducers With Adjustable Deployment Mechanism and Implantation Depth Gauge 审中-公开
    具有可调节部署机制和植入深度计的阀门引导器

    公开(公告)号：US20130268065A1

    公开(公告)日：2013-10-10

    申请号：US13440967

    申请日：2012-04-05

    申请人： Declan Costello ,  Ronan Rogers ,  Edmond Sheahan ,  Damian Carr

    发明人： Declan Costello ,  Ronan Rogers ,  Edmond Sheahan ,  Damian Carr

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2427 ,  A61F2/2433 ,  A61F2002/9517 ,  A61F2250/0007 ,  A61F2250/0065 ,  A61F2250/0097

    摘要： Valve introducer systems and methods for implanting heart valve prostheses are disclosed, where a valve introducer includes an adjustable deployment mechanism comprising a deployment element and an implantation depth controlling element having a distal end and an adjustable length. The valve introducer also includes a tubular member having a distal end, configured to deliver a heart valve prosthesis, and a length extending from a fixed reference point. The implantation depth controlling element can comprise an inner and an outer cylinder, such as where the outer cylinder has interior threads, and the inner cylinder has exterior threads. The adjustable deployment element can include a depth gauge, wherein the depth gauge indicates the length the tubular member extends beyond a fixed reference point. In certain embodiments, the adjustable deployment element can also be configured to be secured to a cannula.

    摘要翻译： 公开了用于植入心脏瓣膜假体的瓣膜导引器系统和方法，其中，阀导入器包括可调部署机构，其包括展开元件和具有远端和可调整长度的植入深度控制元件。 阀导入器还包括具有远端的管状构件，构造成输送心脏瓣膜假体以及从固定参考点延伸的长度。 植入深度控制元件可以包括内筒和外筒，例如外筒具有内螺纹，并且内筒具有外螺纹。 可调式展开元件可以包括深度计，其中深度计指示管状构件延伸超过固定参考点的长度。 在某些实施例中，可调式展开元件也可被构造成固定到套管上。

    Dual valve prosthesis for transcatheter valve implantation
    6.
    发明授权
    Dual valve prosthesis for transcatheter valve implantation 有权
    用于经导管瓣膜植入的双瓣膜假体

    公开(公告)号：US08926694B2

    公开(公告)日：2015-01-06

    申请号：US13432497

    申请日：2012-03-28

    申请人： Declan Costello

    发明人： Declan Costello

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2418 ,  A61F2/2436 ,  A61F2230/0054

    摘要： A dual valve prosthesis having first and second prosthetic valve sections is disclosed. The first prosthetic valve section includes a stent structure with a first prosthetic valve secured therein and the second prosthetic valve section includes an annular frame with a second prosthetic valve secured therein. When the dual valve prosthesis is in an expanded configuration, the annular frame extends from the stent structure such that the first and second prosthetic valves are laterally offset from each other. In a method in accordance herewith, the first and second prosthetic valve sections include prosthetic aortic and mitral valves, respectively, and the dual heart valve prosthesis is configured to replace both the native aortic and mitral valves of the heart in a single transcatheter heart valve implantation procedure.

    摘要翻译： 公开了一种具有第一和第二假体瓣膜部分的双瓣膜假体。 第一假体瓣膜部分包括具有固定在其中的第一假体瓣膜的支架结构，第二假体瓣膜部分包括固定在其中的第二假体瓣膜的环形框架。 当双瓣膜假体处于膨胀构型时，环形框架从支架结构延伸，使得第一和第二假体瓣彼此横向偏移。 在根据本发明的方法中，第一和第二假体瓣膜部分分别包括假体主动脉和二尖瓣，并且双心脏瓣膜假体构造成在单个经导管心脏瓣膜植入中替换心脏的天然主动脉瓣和二尖瓣 程序。

    Trans-Aortic Delivery System With Containment Capsule Centering Device
    7.
    发明申请
    Trans-Aortic Delivery System With Containment Capsule Centering Device 有权
    具有遏制胶囊定心装置的主动脉递送系统

    公开(公告)号：US20140067050A1

    公开(公告)日：2014-03-06

    申请号：US13604150

    申请日：2012-09-05

    申请人： Declan Costello ,  Patrick Griffin ,  John Gallagher ,  Gavin Kenny ,  Edmond Sheahan

    发明人： Declan Costello ,  Patrick Griffin ,  John Gallagher ,  Gavin Kenny ,  Edmond Sheahan

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2436 ,  A61F2/962 ,  A61F2/966 ,  A61F2002/9517 ,  A61F2002/9665

    摘要： Heart valve delivery systems and methods of delivering and implanting heart valves using delivery catheters are disclosed. The delivery systems can include a handle assembly which can include a first control mechanism, a second control mechanism, and a decoupling mechanism. The delivery systems can also include a delivery catheter extending from the handle assembly. The delivery catheter can include an outer shaft, which can be controlled by the first control mechanism; a prosthesis containing capsule comprising a proximal capsule portion connected to the outer shaft, and a distal capsule portion releasably coupled to the proximal capsule portion. After deploying a valve prosthesis, the capsule can be closed by activating the decoupling mechanism in the handle to rapidly close the distal and proximal capsule portions together. The delivery system can also include a centering element to guide the distal and proximal capsule portions together.

    摘要翻译： 公开了使用输送导管递送和植入心脏瓣膜的心脏瓣膜输送系统和方法。 输送系统可以包括手柄组件，其可以包括第一控制机构，第二控制机构和解耦机构。 递送系统还可以包括从手柄组件延伸的递送导管。 输送导管可包括可由第一控制机构控制的外轴; 包含胶囊的假体，其包括连接到所述外轴的近端胶囊部分和可释放地联接到所述近端胶囊部分的远端胶囊部分。 在部署阀门假体之后，可以通过启动手柄中的解耦机构来关闭胶囊，以将远端和近端胶囊部分快速关闭在一起。 输送系统还可以包括将远端和近端胶囊部分一起引导的定心元件。

    Valve introducers with adjustable deployment mechanism and implantation depth gauge
    8.
    发明授权
    Valve introducers with adjustable deployment mechanism and implantation depth gauge 有权

    公开(公告)号：US10376362B2

    公开(公告)日：2019-08-13

    申请号：US13440967

    申请日：2012-04-05

    申请人： Declan Costello ,  Ronan Rogers ,  Edmond Sheahan ,  Damian Carr

    发明人： Declan Costello ,  Ronan Rogers ,  Edmond Sheahan ,  Damian Carr

    IPC分类号： A61F2/24 ,  A61F2/95

    摘要： Valve introducer systems and methods for implanting heart valve prostheses are disclosed, where a valve introducer includes an adjustable deployment mechanism comprising a deployment element and an implantation depth controlling element having a distal end and an adjustable length. The valve introducer also includes a tubular member having a distal end, configured to deliver a heart valve prosthesis, and a length extending from a fixed reference point. The implantation depth controlling element can comprise an inner and an outer cylinder, such as where the outer cylinder has interior threads, and the inner cylinder has exterior threads. The adjustable deployment element can include a depth gauge, wherein the depth gauge indicates the length the tubular member extends beyond a fixed reference point. In certain embodiments, the adjustable deployment element can also be configured to be secured to a cannula.

    Catheter with improved transition section
    10.
    发明授权
    Catheter with improved transition section 失效
    导管改良过渡段

    公开(公告)号：US06905477B2

    公开(公告)日：2005-06-14

    申请号：US10251477

    申请日：2002-09-20

    申请人： Paula McDonnell ,  Mark Casley ,  Declan Costello ,  William Hawkins

    发明人： Paula McDonnell ,  Mark Casley ,  Declan Costello ,  William Hawkins

    IPC分类号： A61M25/01 ,  A61M29/02 ,  A61M31/00

    CPC分类号： A61M25/0169 ,  A61M25/104 ,  A61M2025/107

    摘要： A catheter and guide wire exchange system including a catheter that has a guide wire lumen with a guide way extending along a length of the proximal shaft. A guide member is slidably disposed about the proximal shaft for directing a guide wire into or out of the guide way and the guide wire lumen. A transition section joins the bilumen proximal shaft to a coaxial distal shaft.

    摘要翻译： 一种导管和导丝线交换系统，包括导管，该导管具有沿着近端轴的长度延伸的引导方式的导丝管腔。 引导构件围绕近侧轴线可滑动地设置，用于将引导线引导到导向方式和引导线腔内或引导线腔内。 过渡部分将近侧轴连接到同轴远端轴。