-
公开(公告)号:US20070265261A1
公开(公告)日:2007-11-15
申请号:US11569552
申请日:2005-06-08
申请人: Paul Edwards , Claudia Rosenbaum , Christian Rummey , Silvia Cerezo-Galvez , Achim Feurer , Oliver Hill , Meinolf Thiemann , Victor Matassa , Sonja Nordhoff , Barbara Hoffmann
发明人: Paul Edwards , Claudia Rosenbaum , Christian Rummey , Silvia Cerezo-Galvez , Achim Feurer , Oliver Hill , Meinolf Thiemann , Victor Matassa , Sonja Nordhoff , Barbara Hoffmann
IPC分类号: A61K31/4545 , A61K31/4525 , A61K31/5377 , A61P3/04 , C07D211/06 , C07D211/96 , C07D401/06 , C07D405/06 , C07D413/06
CPC分类号: C07D211/26
摘要: The invention relates to compounds of formula (1) wherein Z, R1-3 and A have the meaning as cited in the description and the claims. Said compounds are useful as DPP-IV inhibitors. The invention also relates to the preparation of such compounds as well as the production and use thereof as medicament.
摘要翻译: 本发明涉及式(1)的化合物,其中Z,R 1-3和A具有在说明书和权利要求书中引用的含义。 所述化合物可用作DPP-IV抑制剂。 本发明还涉及这种化合物的制备以及其作为药物的生产和使用。