公开(公告)号：US06627124B1

公开(公告)日：2003-09-30

申请号：US09530073

申请日：2000-12-14

申请人： Peter Herbrechtsmeier ,  Peter Hagmann ,  Roger Biel ,  Axel Heinrich ,  Wilhelm Hörner ,  Egbert Jux ,  Anette Therese Lang-Schöll ,  Iris Jlona Leder-Brück ,  Achim Müller ,  Bernhard Seiferling ,  Werner Steffan

发明人： Peter Herbrechtsmeier ,  Peter Hagmann ,  Roger Biel ,  Axel Heinrich ,  Wilhelm Hörner ,  Egbert Jux ,  Anette Therese Lang-Schöll ,  Iris Jlona Leder-Brück ,  Achim Müller ,  Bernhard Seiferling ,  Werner Steffan

IPC分类号： B29D1100

CPC分类号： B29D11/00125 ,  B29C35/02 ,  B29C35/0888 ,  B29C2035/0827 ,  B29C2035/085 ,  B29C2035/0877 ,  B29K2909/08 ,  Y10S425/808

摘要： The invention tackles the problem of improving the production process for contact lenses further, so that the production costs for contact lenses can be reduced further and the production capacities can be increased. To this end, provision is made for the two mould halves, which together form the mould for producing a contact lens, to be fixed to each other and/or detachably connected to each other by means of individual half-mould guide. In conjunction with a cyclic production process, a high degree of automation can be achieved in this way.

摘要翻译： 本发明还解决了进一步改进隐形眼镜的制造工艺的问题，能够进一步降低隐形眼镜的制造成本，提高生产能力。 为此，为了通过单独的半模引导件彼此固定和/或可拆卸地彼此固定的两个半模一起形成用于制造隐形眼镜的模具。 结合循环生产过程，可以以这种方式实现高度的自动化。

公开(公告)号：US6113817A

公开(公告)日：2000-09-05

申请号：US47041

申请日：1998-03-24

申请人： Peter Herbrechtsmeier ,  Karl Baur ,  Roger Biel ,  John Golby ,  Roland Hauck ,  Peter Hagmann ,  Axel Heinrich ,  Otto Kretzschmar ,  Anette Lang ,  Achim Muller ,  Thomas Schulz ,  Bernhard Seiferling ,  Werner Steffan

发明人： Peter Herbrechtsmeier ,  Karl Baur ,  Roger Biel ,  John Golby ,  Roland Hauck ,  Peter Hagmann ,  Axel Heinrich ,  Otto Kretzschmar ,  Anette Lang ,  Achim Muller ,  Thomas Schulz ,  Bernhard Seiferling ,  Werner Steffan

IPC分类号： B29D11/00

CPC分类号： B29D11/0023 ,  B08B9/00 ,  B29D11/00259 ,  B08B3/02

摘要： Efficient and consistent processes for manufacturing moldings, especially ophthalmic lenses such as contact lenses. The processes comprises a series of improvements, including improvements in the areas of conditions for dispensing liquid prepolymer into lens molds, male and female mold mating, reusable molds, mold cleaning, lens separation from molds (demolding), lens handling, and in-line inspection. Cyclic series of processing steps are also disclosed. Additionally, an improved molding tool is disclosed, with the molding tool including a male mold housing and a female mold housing, each of which have disposed therein a plurality of mold halves.

摘要翻译： 用于制造模制品的高效且一致的工艺，特别是诸如隐形眼镜的眼镜。 这些方法包括一系列改进，包括将液体预聚物分配到透镜模具中的条件的改进，阳模和阴模配合，可重复使用的模具，模具清洁，与模具分离的透镜（脱模），透镜处理和在线 检查。 还公开了循环系列的处理步骤。 此外，公开了一种改进的模制工具，其中模制工具包括阳模壳体和阴模壳体，每个模具壳体中设置有多个半模。

公开(公告)号：US06342570B1

公开(公告)日：2002-01-29

申请号：US09280789

申请日：1999-03-26

申请人： Harald Bothe ,  Achim Müller ,  Bernhard Seiferling ,  Sharla Borghorst ,  John Golby ,  Peter Hagmann ,  Peter Herbrechtsmeier ,  Otto Kretzschmar

发明人： Harald Bothe ,  Achim Müller ,  Bernhard Seiferling ,  Sharla Borghorst ,  John Golby ,  Peter Hagmann ,  Peter Herbrechtsmeier ,  Otto Kretzschmar

IPC分类号： C08F2608

CPC分类号： C08F293/005 ,  C08F8/00 ,  C08F226/06 ,  C08F226/10 ,  C08F2810/30 ,  C08F2220/281 ,  C08F2220/343 ,  C08F220/36 ,  C08F220/14 ,  C08F2220/325

摘要： The present invention describes novel statistical copolymers and the preparation and possible uses thereof. Copolymers are described that are water-soluble and cross-linkable and that comprise the copolymerization product of a monomer mixture consisting substantially of a vinyl lactam (a) and at least one further vinyl monomer (b) of a different type selected from the group consisting of hydrophobic, hydrophilic and functional vinyl monomers, wherein the monomers are present in the copolymer in the form of statistically distributed building blocks, and, if a functional vinyl monomer is present as a building block in the copolymer, that building block is, where appropriate, modified with a reactive vinyl monomer (c), the reactive vinyl monomer (c) being linked to a building block of a functional vinyl monomer with retention of its vinylic group and with the formation of a covalent bond.

摘要翻译： 本发明描述了新的统计共聚物及其制备及其可能用途。 描述了共聚物是水溶性和可交联的，并且包含基本上由乙烯基内酰胺（a）和至少一种另外的不同类型的乙烯基单体（b）组成的单体混合物的共聚产物，其选自 的疏水性，亲水性和功能性的乙烯基单体，其中单体以统计分布的结构单元的形式存在于共聚物中，并且如果官能的乙烯基单体作为共聚物中的结构单元存在，则该结构单元在适当的情况下 ，用反应性乙烯基单体（c）改性，反应性乙烯基单体（c）与保持其乙烯基基团并形成共价键的官能乙烯基单体的结构单元连接。

公开(公告)号：US08580163B2

公开(公告)日：2013-11-12

申请号：US12904209

申请日：2010-10-14

申请人： Roger Biel ,  Gabriela Cocora ,  Peter Hagmann ,  Uwe Haken ,  Jordan Hall ,  Axel Heinrich ,  Günter Lässig ,  Honghui Lu ,  Deborah J. Mulcahy ,  Carlton Pope ,  Daryl Reece ,  Bernhard Seiferling

发明人： Roger Biel ,  Gabriela Cocora ,  Peter Hagmann ,  Uwe Haken ,  Jordan Hall ,  Axel Heinrich ,  Günter Lässig ,  Honghui Lu ,  Deborah J. Mulcahy ,  Carlton Pope ,  Daryl Reece ,  Bernhard Seiferling

IPC分类号： B29D11/00

CPC分类号： B29C33/20 ,  B29C37/005 ,  B29C43/02 ,  B29C43/36 ,  B29D11/00125 ,  B29L2011/0016

摘要： There is described a process for manufacturing an ophthalmic lens and an apparatus for forming an ophthalmic lens, in particular a silicone hydrogel contact lens, wherein in a mold assembly a first and a second mold half (101, 102) are first arranged in an intermediate closed position in which the mold surfaces of the two mold halves are spaced apart from each other at a distance increase (d1) of preferably 1 to 100 μm relative to a final distance (d0) in a final closed position, and wherein, during curing of the lens forming material (202), the mold surfaces (105, 106) of the mold halves (101, 102) are actively or passively moved or moving from the intermediate closed position to the final closed position, where the distance increase (d1) is 0.

摘要翻译： 描述了用于制造眼科镜片的方法和用于形成眼用透镜，特别是硅酮水凝胶隐形眼镜的装置，其中在模具组件中，第一和第二半模（101,102）首先被布置在中间体 关闭位置，其中两个半模的模具表面在最终关闭位置中相对于最终距离（d0）以优选1至100μm的距离增加（d1）彼此间隔开，并且其中在固化期间 透镜形成材料（202）的两个半模（101,102）的模具表面（105,106）被主动地或被动地从中间关闭位置移动或移动到最终关闭位置，其中距离增加（d1 ）为0。

公开(公告)号：US20070001329A1

公开(公告)日：2007-01-04

申请号：US11452537

申请日：2006-06-14

申请人： Peter Hagmann ,  Axel Heinrich ,  Iris Leder-Bruck ,  Bernhard Seiferling ,  Werner Steffan

发明人： Peter Hagmann ,  Axel Heinrich ,  Iris Leder-Bruck ,  Bernhard Seiferling ,  Werner Steffan

IPC分类号： B29D11/00

CPC分类号： B29D11/0023 ,  B29C31/045 ,  B29L2011/0041 ,  Y10S425/808

摘要： A process of dosing a starting material (SM) for optical lenses, into a female mould half (2), comprises the steps of: positioning a dosing tip (1) at a start position (P2) above the female mould half (2) and close to the edge of or laterally outside that portion (20) defining the lens-shaping surface, creating a continuous flow of starting material (SM) through the dosing tip (1) into the female mould half (2), moving the dosing tip (1) from the start position (P2) towards an end position (P3) in the region of the centre of the female mould half (2) once the starting material (SM) has contacted the surface (21) of the female mould half (2) with the dosing tip (1) being in the start position (P2), wherein the continuous flow of starting material (SM) through the dosing tip (1) and the movement of the dosing tip (1) from the start position (P2) to its end position (P3) are controlled such, that a continuous bead (B) of starting material (SM) is deposited on the surface (21) of the female mould half (2) and that the essential part of the overall volume of starting material (SM) dosed into the female mould half (2) is deposited within the female mould half (2) with the dosing tip (1) being in the end position (P3).

摘要翻译： 将用于光学透镜的起始材料（SM）投入到阴半模（2）中的过程包括以下步骤：将定量给料头（1）定位在母模半部（2）上方的起始位置（P 2） ）并且靠近限定透镜成形表面的该部分（20）的边缘或侧向外侧，从而通过配量末端（1）产生连续的起始材料流（SM）到阴模半体（2）中， 一旦起始材料（SM）接触了表面（21），母模半部（2）的中心区域中，将起始位置（P 2）从起始位置（P 2）向端部位置（P 3） 具有给药尖端（1）的母模半部（2）处于起始位置（P 2），其中通过定量给料头（1）的起始材料（SM）的连续流动和给药末端（1）的运动 ）从起始位置（P 2）到其结束位置（P 3）被控制为使得起始材料（SM）的连续珠（B） 位于阴半模（2）的表面（21）上，并且投入到阴半模（2）中的起始材料（SM）的总体积的主要部分被沉积在阴半模（2）内， 剂量尖端（1）处于最终位置（P 3）。

公开(公告)号：US20110089586A1

公开(公告)日：2011-04-21

申请号：US12904209

申请日：2010-10-14

申请人： Roger Biel ,  Gabriela Cocora ,  Peter Hagmann ,  Uwe Haken ,  Jordan Hall ,  Axel Heinrich ,  Günter Lässig ,  Honghui Lu ,  Deborah J. Mulcahy ,  Carlton Pope ,  Daryl Reece ,  Bernhard Seiferling

发明人： Roger Biel ,  Gabriela Cocora ,  Peter Hagmann ,  Uwe Haken ,  Jordan Hall ,  Axel Heinrich ,  Günter Lässig ,  Honghui Lu ,  Deborah J. Mulcahy ,  Carlton Pope ,  Daryl Reece ,  Bernhard Seiferling

IPC分类号： B29D11/00 ,  B29C33/20

CPC分类号： B29C33/20 ,  B29C37/005 ,  B29C43/02 ,  B29C43/36 ,  B29D11/00125 ,  B29L2011/0016

摘要： There is described a process for manufacturing an ophthalmic lens and an apparatus for forming an ophthalmic lens, in particular a silicone hydrogel contact lens, wherein in a mold assembly a first and a second mold half (101, 102) are first arranged in an intermediate closed position in which the mold surfaces of the two mold halves are spaced apart from each other at a distance increase (d1) of preferably 1 to 100 μm relative to a final distance (d0) in a final closed position, and wherein, during curing of the lens forming material (202), the mold surfaces (105, 106) of the mold halves (101, 102) are actively or passively moved or moving from the intermediate closed position to the final closed position, where the distance increase (d1) is 0.

摘要翻译： 描述了用于制造眼科镜片的方法和用于形成眼用透镜，特别是硅酮水凝胶隐形眼镜的装置，其中在模具组件中，第一和第二半模（101,102）首先被布置在中间体 关闭位置，其中两个半模的模具表面相对于最终关闭位置相对于最终距离（d0）在距离增加（d1）优选为1至100μm的间距彼此间隔开，并且其中，在固化期间 透镜形成材料（202）的两个半模（101,102）的模具表面（105,106）被主动地或被动地从中间关闭位置移动或移动到最终关闭位置，其中距离增加（d1 ）为0。

公开(公告)号：US07682532B2

公开(公告)日：2010-03-23

申请号：US11452537

申请日：2006-06-14

申请人： Peter Hagmann ,  Axel Heinrich ,  Iris Leder-Bruck ,  Bernhard Seiferling ,  Werner Steffan

发明人： Peter Hagmann ,  Axel Heinrich ,  Iris Leder-Bruck ,  Bernhard Seiferling ,  Werner Steffan

IPC分类号： B29D11/00

CPC分类号： B29D11/0023 ,  B29C31/045 ,  B29L2011/0041 ,  Y10S425/808

摘要： A process of dosing a starting material (SM) for optical lenses, into a female mold half (2), comprises the steps of: positioning a dosing tip (1) at a start position (P2) above the female mold half (2) and close to the edge of or laterally outside that portion (20) defining the lens-shaping surface, creating a continuous flow of starting material (SM) through the dosing tip (1) into the female mold half (2), moving the dosing tip (1) from the start position (P2) towards an end position (P3) in the region of the center of the female mold half (2) once the starting material (SM) has contacted the surface (21) of the female mold half (2) with the dosing tip (1) being in the start position (P2), wherein the continuous flow of starting material (SM) through the dosing tip (1) and the movement of the dosing tip (1) from the start position (P2) to its end position (P3) are controlled such, that a continuous bead (B) of starting material (SM) is deposited on the surface (21) of the female mold half (2) and that the essential part of the overall volume of starting material (SM) dosed into the female mold half (2) is deposited within the female mold half (2) with the dosing tip (1) being in the end position (P3).

摘要翻译： 将用于光学透镜的起始材料（SM）投入到阴半模（2）中的过程包括以下步骤：将定量给料头（1）定位在阴半模（2）上方的起始位置（P2） 并且靠近限定透镜成形表面的该部分（20）的边缘或侧向外侧，从而通过定量给料头（1）产生连续的起始材料流（SM）进入阴模半部（2） 一旦起始材料（SM）已经接触阴模的表面（21），在阴模半部（2）的中心区域中从尖端（1）开始位置（P2）到端部位置（P3） 一半（2），其中所述给料尖端（1）处于所述起始位置（P2），其中通过所述计量末端（1）的起始材料（SM）的连续流动和所述计量末端（1） 位置（P2）到其结束位置（P3）被控制为使得在母体的表面（21）上沉积起始材料（SM）的连续珠（B） d半（2），并且计量到阴半模（2）中的起始材料（SM）的总体积的主要部分被沉积在阴半模（2）内，而配量尖端（1）处于最终 位置（P3）。

公开(公告)号：US5712356A

公开(公告)日：1998-01-27

申请号：US339384

申请日：1994-11-14

申请人： Harald Bothe ,  Achim Muller ,  Bernhard Seiferling ,  Sharla Borghorst ,  John Golby ,  Peter Hagmann ,  Peter Herbrechtsmeier ,  Otto Kretzschmar

发明人： Harald Bothe ,  Achim Muller ,  Bernhard Seiferling ,  Sharla Borghorst ,  John Golby ,  Peter Hagmann ,  Peter Herbrechtsmeier ,  Otto Kretzschmar

IPC分类号： G02C7/04 ,  C08F8/00 ,  C08F16/08 ,  C08F16/14 ,  C08F20/26 ,  C08F20/52 ,  C08F26/00 ,  C08F216/08 ,  C08F216/14 ,  C08F218/02 ,  C08F218/04 ,  C08F220/04 ,  C08F220/06 ,  C08F220/28 ,  C08F220/56 ,  C08F226/06 ,  C08F226/10 ,  C08F246/00 ,  C08F293/00 ,  C08F299/00 ,  G02B1/04 ,  C08F220/18 ,  C08F224/00 ,  C08F226/02 ,  C08F228/02

CPC分类号： C08F226/06 ,  C08F293/005 ,  C08F8/14 ,  G02B1/043 ,  C08F226/10 ,  C08F2800/10 ,  C08F2800/20 ,  C08F2810/20 ,  C08F2810/50

摘要： The present invention describes novel statistical copolymers and the preparation and possible uses thereof. Copolymers are described that are water-soluble and cross-linkable and that comprise the copolymerisation product of a monomer mixture consisting substantially of a vinyl lactam (a) and at least one further vinyl monomer (b) of a different type selected from the group consisting of hydrophobic, hydrophilic and functional vinyl monomers, wherein the monomers are present in the copolymer in the form of statistically distributed building blocks, and, if a functional vinyl monomer is present as a building block in the copolymer, that building block is, where appropriate, modified with a reactive vinyl monomer (c), the reactive vinyl monomer (c) being linked to a building block of a functional vinyl monomer with retention of its vinylic group and with the formation of a covalent bond.

摘要翻译： 本发明描述了新的统计共聚物及其制备及其可能用途。 描述了共聚物是水溶性和可交联的，并且包含基本上由乙烯基内酰胺（a）和至少一种另外的不同类型的乙烯基单体（b）组成的单体混合物的共聚产物，所述另外的乙烯基单体（b）选自 的疏水性，亲水性和功能性的乙烯基单体，其中单体以统计分布的结构单元的形式存在于共聚物中，并且如果官能的乙烯基单体作为共聚物中的结构单元存在，则该结构单元在适当的情况下 ，用反应性乙烯基单体（c）改性，反应性乙烯基单体（c）与保持其乙烯基基团并形成共价键的官能乙烯基单体的结构单元连接。

公开(公告)号：US5609246A

公开(公告)日：1997-03-11

申请号：US434088

申请日：1995-05-03

申请人： Sharla Borghorst ,  Erich Baumann ,  John Golby ,  Peter Hagmann ,  Peter Herbrechtsmeier ,  Otto Kretzschmar ,  Bernhard Seiferling ,  Michele De Lucchi ,  Torsten Fritze ,  Masahiko Cubo

发明人： Sharla Borghorst ,  Erich Baumann ,  John Golby ,  Peter Hagmann ,  Peter Herbrechtsmeier ,  Otto Kretzschmar ,  Bernhard Seiferling ,  Michele De Lucchi ,  Torsten Fritze ,  Masahiko Cubo

IPC分类号： A45C11/04 ,  A61F2/16 ,  B65D1/30 ,  B65D1/36 ,  B65D75/36 ,  B65D77/20 ,  B65D81/24

CPC分类号： B65D77/2036 ,  A61F2/1691 ,  B65D1/30 ,  B65D2585/545 ,  Y10S134/901

摘要： The blister pack comprises a base portion and a cover layer. The base portion comprises a hollow chamber that contains a soft hydrophilic contact lens and a sterile aqueous preserving solution, and a substantially flat flange that extends right round the outside of the hollow chamber. The cover layer is releasably sealed to the flange in a sealing zone that extends right round the circumference of the hollow chamber. The flange comprises a grip region that extends from one side of the hollow chamber beyond the sealing zone and is covered by a corresponding grip region of the cover layer but is not sealed thereto. The hollow chamber comprises a dish-shaped main chamber and, adjoining the side of that main chamber, a secondary chamber in the shape of a channel tapering on all sides away from the main chamber, the main chamber making a smooth transition into the secondary chamber, and the main chamber and the secondary chamber together having a drop-shaped contour in the plane of the flange, the tip of which contour is directed towards the grip region of the flange. Provided in the grip region of the flange is an oval opening by means of which the overlying grip region of the cover layer can be lifted from the flange. A support element that is angled with respect to the plane of the flange is arranged in the grip region of the flange. An angled grip element or facilitating the handling of the blister pack is arranged at the edge of the flange on both sides of the hollow chamber. The base portion is so shaped that the blister packs can be nested in pairs with their undersides one inside the other, in each case the hollow chamber of one blister pack lying in the region of the grip region of the other blister pack. The blister pack is extremely handy, space-saving and stable, requires only an extremely small amount of preserving solution and enables the contact lens it contains to be removed especially easily.

摘要翻译： 泡罩包装包括基部和覆盖层。 底座部分包括一个包含柔软的亲水性隐形眼镜和无菌水性保存液的中空腔，以及在中空腔外侧向外延伸的基本平坦的凸缘。 覆盖层在密封区域中可释放地密封到凸缘上，密封区域在中空室的圆周的右侧延伸。 凸缘包括从中空室的一侧延伸超过密封区并被覆盖层的相应夹持区域覆盖但不被密封的手柄区域。 中空室包括碟形主室，并且邻近该主室的一侧，具有在远离主室的所有侧面上渐缩的通道形式的第二室，主室平滑地过渡到次室 ，并且主室和副室一起在凸缘的平面中具有液滴形轮廓，其顶端的轮廓指向凸缘的把手区域。 在凸缘的把手区域中设置有椭圆形的开口，通过该椭圆形开口可以覆盖层的覆盖夹持区域从凸缘提升。 相对于凸缘的平面成角度的支撑元件布置在凸缘的把手区域中。 倾斜的夹紧元件或便于处理泡罩包装被布置在中空室两侧的凸缘的边缘处。 底部部分是这样成形的，使得泡罩包装件可以与它们的下侧成对嵌套，一个在另一个内部，在每种情况下，一个泡罩包装袋的中空室位于另一个泡罩包装的抓握区域的区域中。 泡罩包装非常方便，节省空间并且稳定，只需要极少量的保存溶液，并且使其包含的隐形眼镜被特别容易地去除。

公开(公告)号：US06800225B1

公开(公告)日：2004-10-05

申请号：US08274942

申请日：1994-07-14

申请人： Peter Hagmann ,  Sharla Borghorst ,  John Golby ,  Peter Herbrechtsmeier ,  Otto Kretzschmar ,  Bernhard Seiferling ,  Norbert Söllner ,  Beat Müller

发明人： Peter Hagmann ,  Sharla Borghorst ,  John Golby ,  Peter Herbrechtsmeier ,  Otto Kretzschmar ,  Bernhard Seiferling ,  Norbert Söllner ,  Beat Müller

IPC分类号： B29D1100

CPC分类号： B29D11/00442 ,  B29C31/041 ,  B29C33/06 ,  B29C33/303 ,  B29C35/0894 ,  B29C37/0003 ,  B29C37/0007 ,  B29C37/005 ,  B29C37/02 ,  B29C39/24 ,  B29C39/36 ,  B29C39/42 ,  B29C2035/0827 ,  B29D11/00057 ,  B29D11/00134 ,  B29L2011/0041 ,  Y10S425/808

摘要： A measured amount of a material that is crosslinkable by impingement of a suitable form of energy, especially UV light, is introduced into a two-part mould of which cavity determines the shape of a moulding to be produced. The two mould halves are held a small distance from one another so that a thin annular gap is formed between them, which gap is in communication with the mould cavity and through which gap excess material can escape. The crosslinking is triggered by impingement of the selected form of energy, the impingement being spatially restricted to the cavity by suitable masking so that material disposed outside the mould cavity is not crosslinked. In that manner mouldings are obtained that do not require subsequent mechanical processing, and the mould is reusable. The process is especially, but not, however, exclusively, suitable for the manufacture of contact lenses.

摘要翻译： 通过冲击适当形式的能量，特别是UV光可交联的材料的测量量被引入到其中空腔确定待生产的模制品的形状的两部分模具中。 两个半模彼此保持很小的距离，使得它们之间形成薄的环形间隙，该间隙与模腔连通，并且间隙多余的材料可以逸出。 通过所选择的能量的冲击来触发交联，通过适当的掩蔽将冲击空间限制在空腔中，使得设置在模腔外部的材料不交联。 以这种方式获得不需要后续机械加工的模制品，并且模具是可重复使用的。 该方法特别但并不仅仅是适用于隐形眼镜的制造。