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公开(公告)号:US20050053987A1
公开(公告)日:2005-03-10
申请号:US10893888
申请日:2004-07-20
申请人: Preeti Lal , Karl Guegler , Gina Gorgone , Neil Corley , Mariah Baughn , Y. Tang , Jennifer Hillman , Olga Bandman , Yalda Azimzai , Janice Au-Young , Henry Yue , Dyung Lu , Junming Yang
发明人: Preeti Lal , Karl Guegler , Gina Gorgone , Neil Corley , Mariah Baughn , Y. Tang , Jennifer Hillman , Olga Bandman , Yalda Azimzai , Janice Au-Young , Henry Yue , Dyung Lu , Junming Yang
CPC分类号: C12N9/0004 , A61K38/00
摘要: The invention provides human oxidoreductase molecules (OXRE) and polynucleotides which identify and encode OXRE. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of OXRE.
摘要翻译: 本发明提供人氧化还原酶分子(OXRE)和识别和编码OXRE的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与OXRE表达相关的障碍的方法。
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公开(公告)号:US20050181415A1
公开(公告)日:2005-08-18
申请号:US11079743
申请日:2005-03-14
申请人: Junming Yang , Mariah Baughn , Neil Burford , Janice Au-Young , Dyung Lu , Roopa Reddy , Huijun Ring , Jennifer Hillman , Henry Yue , Yalda Azimzai , Monique Yao , Ameena Gandhi , Danniel Nguyen , Y. Tang , Preeti Lal , Olga Bandman
发明人: Junming Yang , Mariah Baughn , Neil Burford , Janice Au-Young , Dyung Lu , Roopa Reddy , Huijun Ring , Jennifer Hillman , Henry Yue , Yalda Azimzai , Monique Yao , Ameena Gandhi , Danniel Nguyen , Y. Tang , Preeti Lal , Olga Bandman
IPC分类号: A61K38/00 , A61K45/06 , C12N9/00 , C12Q1/26 , G01N33/68 , C12Q1/68 , A01K67/00 , C07H21/04 , C12N15/85
CPC分类号: C12Y101/01001 , A61K38/00 , A61K45/06 , C12N9/00 , C12Q1/26 , C12Y205/01018 , G01N33/6893 , G01N2500/00
摘要: The invention provides human drug metabolizing enzymes (DME) and polynucleotides which identify and encode DME. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of DME.
摘要翻译: 本发明提供了人类代谢酶(DME)和识别和编码DME的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与DME的异常表达相关的紊乱的方法。
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公开(公告)号:US20050048623A1
公开(公告)日:2005-03-03
申请号:US10959539
申请日:2004-10-06
申请人: Jennifer Hillman , Preeti Lal , Y. Tang , Henry Yue , Janice Au-Young , Olga Bandman , Yalda Azimzai , Junming Yang , Dyung Lu , Mariah Baughn , Chandra Arvizu , Purvi Shah
发明人: Jennifer Hillman , Preeti Lal , Y. Tang , Henry Yue , Janice Au-Young , Olga Bandman , Yalda Azimzai , Junming Yang , Dyung Lu , Mariah Baughn , Chandra Arvizu , Purvi Shah
CPC分类号: C07K14/47 , A01K2217/05 , A61K38/00
摘要: The invention provides human cell cycle and proliferation proteins (CCYPR) and polynucleotides which identify and encode CCYPR. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of CCYPR.
摘要翻译: 本发明提供鉴定和编码CCYPR的人类细胞周期和增殖蛋白(CCYPR)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了用于诊断,治疗或预防与CCYPR表达相关的疾病的方法。
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公开(公告)号:US20050048610A1
公开(公告)日:2005-03-03
申请号:US10874706
申请日:2004-06-24
申请人: Preeti Lal , Junming Yang , Henry Yue , Jennifer Jackson , Y. Tang , Olga Bandman , Neil Burford , Mariah Baughn , Yalda Azimzai , Dyung Lu , Janice Au-Young , Chandra Arvizu
发明人: Preeti Lal , Junming Yang , Henry Yue , Jennifer Jackson , Y. Tang , Olga Bandman , Neil Burford , Mariah Baughn , Yalda Azimzai , Dyung Lu , Janice Au-Young , Chandra Arvizu
IPC分类号: A61K38/00 , C07K14/47 , C07K14/705 , C07H21/04
CPC分类号: C07K14/705 , A01K2217/05 , A61K38/00 , C07K14/47
摘要: This invention relates to nucleic acid and amino acid sequences of human transport proteins and to the use of these sequences in the diagnosis, treatment, and prevention of transport, metabolic, neurological, cardiovascular, reproductive, and immune disorders, and cell proliferative disorders including cancer.
摘要翻译: 本发明涉及人类运输蛋白的核酸和氨基酸序列,以及这些序列用于诊断,治疗和预防运输,代谢,神经,心血管,生殖和免疫疾病以及包括癌症的细胞增殖性疾病 。
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公开(公告)号:US20060194275A1
公开(公告)日:2006-08-31
申请号:US10474894
申请日:2002-04-12
申请人: Mariah Baughn , Vicki Elliott , April Hafalia , Junming Yang , Narinder Chawla , Jayalaxmi Ramkumar , Ian Forsythe , Yan Lu , Y Tom Tang , Henry Yue , Brigitte Raumann , Preeti Lal , Yalda Azimzai , Dyung Lu , Ameena Gandhi , Michael Thornton , Danniel Nguyen , Chandra Arvizu , Brooke Emerling , Anita Swarnakar , Monique Yao , Li Ding , Ann He , Jennifer Griffin , Madhusudan Sanjanwala , Kimberly Gietzen , Ernestine Lee , Yuming Xu , Janice Au-Young , Debopriya Das , Soo Lee , Hsin-Ru Chang
发明人: Mariah Baughn , Vicki Elliott , April Hafalia , Junming Yang , Narinder Chawla , Jayalaxmi Ramkumar , Ian Forsythe , Yan Lu , Y Tom Tang , Henry Yue , Brigitte Raumann , Preeti Lal , Yalda Azimzai , Dyung Lu , Ameena Gandhi , Michael Thornton , Danniel Nguyen , Chandra Arvizu , Brooke Emerling , Anita Swarnakar , Monique Yao , Li Ding , Ann He , Jennifer Griffin , Madhusudan Sanjanwala , Kimberly Gietzen , Ernestine Lee , Yuming Xu , Janice Au-Young , Debopriya Das , Soo Lee , Hsin-Ru Chang
IPC分类号: C07K14/705 , C07H21/04 , C12P21/06
CPC分类号: C12Q1/6886 , A61K31/706 , A61K38/00 , A61K48/00 , C07K14/4703 , C12Q1/683 , C12Q1/6858 , C12Q2600/154 , C12Q2600/158 , C12Q2521/331 , C12Q2531/113 , C12Q2523/125
摘要: The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.
摘要翻译: 本发明提供了识别和编码TRICH的人转运体和离子通道(TRICH)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与TRICH异常表达相关的紊乱的方法。
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公开(公告)号:US20050260708A1
公开(公告)日:2005-11-24
申请号:US11071580
申请日:2005-03-04
申请人: Henry Yue , Preeti Lal , Y. Tang , Olga Bandman , Mariah Baughn , Yalda Azimzai , Dyung Aina Lu , Junming Yang
发明人: Henry Yue , Preeti Lal , Y. Tang , Olga Bandman , Mariah Baughn , Yalda Azimzai , Dyung Aina Lu , Junming Yang
IPC分类号: G01N33/50 , A61K38/00 , A61K45/00 , A61P43/00 , C07K14/81 , C07K16/40 , C12N1/15 , C12N1/19 , C12N5/10 , C12N9/48 , C12N9/64 , C12N15/09 , C12Q1/02 , C12Q1/37 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , C07H21/04 , C12N9/00 , C12P21/06
CPC分类号: C12N9/6421 , A01K2217/05 , A61K38/00 , C07K14/81 , C12N9/48
摘要: The invention provides human proteases and protease inhibitors (PPIM) and polynucleotides which identify and encode PPIM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of PPIM.
摘要翻译: 本发明提供鉴定和编码PPIM的人类蛋白酶和蛋白酶抑制剂(PPIM)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了用于诊断,治疗或预防与PPIM表达相关的疾病的方法。
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公开(公告)号:US20050069878A1
公开(公告)日:2005-03-31
申请号:US10481041
申请日:2002-06-12
申请人: Henry Yue , Dyung Lu , April Hafalia , Chandra Arvizu , Jayalaxmi Ramkumar , Y Tang , Farrah Khan , Barrie Greene , Thomas Richardson , Junming Yang , Craig Ison , Bridget Warren , Vicki Elliott , Brooke Emerling , Ann Gorvard , Ernestine Lee , Jennifer Griffin , Yeganeh Zebarjadian , Anita Swarnakar , Preeti Lal , Mariah Baughn , Uyen Tran , Sally Lee , Ian Forsythe , Janice Au-Young
发明人: Henry Yue , Dyung Lu , April Hafalia , Chandra Arvizu , Jayalaxmi Ramkumar , Y Tang , Farrah Khan , Barrie Greene , Thomas Richardson , Junming Yang , Craig Ison , Bridget Warren , Vicki Elliott , Brooke Emerling , Ann Gorvard , Ernestine Lee , Jennifer Griffin , Yeganeh Zebarjadian , Anita Swarnakar , Preeti Lal , Mariah Baughn , Uyen Tran , Sally Lee , Ian Forsythe , Janice Au-Young
IPC分类号: G01N33/50 , A01K67/00 , A61K38/00 , A61K39/395 , A61K45/00 , A61K48/00 , A61P1/16 , A61P3/10 , A61P7/06 , A61P9/10 , A61P11/00 , A61P11/06 , A61P15/00 , A61P15/10 , A61P17/06 , A61P19/00 , A61P19/02 , A61P19/06 , A61P21/00 , A61P25/00 , A61P25/08 , A61P25/16 , A61P25/20 , A61P25/28 , A61P27/06 , A61P27/12 , A61P29/00 , A61P31/04 , A61P31/12 , A61P31/18 , A61P33/00 , A61P35/00 , A61P35/02 , A61P37/00 , A61P37/08 , C07H21/04 , C07K1/14 , C07K14/47 , C07K14/475 , C07K16/18 , C07K16/46 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/64 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53
CPC分类号: C07K14/4702 , A01K2217/05 , A61K38/00 , C07K14/4747
摘要: Various embodiments of the invention provide human proteins associated with cell growth, differentiation, and death (CGDD) and polynucleotides which identify and encode CGDD. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CGDD.
摘要翻译: 本发明的各种实施方案提供与细胞生长,分化和死亡(CGDD)相关的人类蛋白质和鉴定和编码CGDD的多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与CGDD异常表达相关的紊乱的方法。
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公开(公告)号:US20050239126A1
公开(公告)日:2005-10-27
申请号:US11167040
申请日:2005-06-27
申请人: Stephen Todd , Angelo Delegeane , Ameena Gandhi , Danniel Nguyen , April Hafalia , Liam Kearney , Yan Lu , Ernestine Lee , Narinder Chawla , Debopriya Das , Chandra Arvizu , Monique Yao , Deborah Kallick , Vicki Elliott , Li Ding , Henry Yue , Roopa Reddy , Dyung Lu , Jayalaxmi Ramkumar , Junming Yang , Catherine Tribouley , Neil Burford , Mariah Baughn , Preeti Lal , Mark Borowsky , Farrah Khan , Rajagopal Gururajan , Y. Tang , Janice Au-Young , Bridget Warren , Roberto Hernandez , Brendan Duggan
发明人: Stephen Todd , Angelo Delegeane , Ameena Gandhi , Danniel Nguyen , April Hafalia , Liam Kearney , Yan Lu , Ernestine Lee , Narinder Chawla , Debopriya Das , Chandra Arvizu , Monique Yao , Deborah Kallick , Vicki Elliott , Li Ding , Henry Yue , Roopa Reddy , Dyung Lu , Jayalaxmi Ramkumar , Junming Yang , Catherine Tribouley , Neil Burford , Mariah Baughn , Preeti Lal , Mark Borowsky , Farrah Khan , Rajagopal Gururajan , Y. Tang , Janice Au-Young , Bridget Warren , Roberto Hernandez , Brendan Duggan
CPC分类号: C12N9/6421 , A01K2217/05 , A01K2217/075 , C07H21/04 , C12N9/6472 , C12Q1/6837 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , Y02A50/52
摘要: The invention provides human proteases (PRTS) and polynucleotides which identify and encode PRTS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PRTS.
摘要翻译: 本发明提供鉴定和编码PRTS的人类蛋白酶(PRTS)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供诊断,治疗或预防与PRTS异常表达相关的疾病的方法。
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公开(公告)号:US20070092885A1
公开(公告)日:2007-04-26
申请号:US11378616
申请日:2006-03-20
申请人: Henry Yue , Monique Yao , Ameena Gandhi , Mariah Baughn , Anita Swarnakar , Narinder Chawla , Madhusudan Sanjanwala , Michael Thornton , Vicki Elliott , Yan Lu , Kimberly Gietzen , Neil Burford , Li Ding , April Hafalia , Y. Tang , Olga Bandman , Bridget Warren , Cynthia Honchell , Dyung Lu , Kavitha Thangavelu , Sally Lee , Yuming Xu , Junming Yang , Preeti Lal , Bao Tran , Craig Ison , Brendan Duggan , Stephanie Sapperstein
发明人: Henry Yue , Monique Yao , Ameena Gandhi , Mariah Baughn , Anita Swarnakar , Narinder Chawla , Madhusudan Sanjanwala , Michael Thornton , Vicki Elliott , Yan Lu , Kimberly Gietzen , Neil Burford , Li Ding , April Hafalia , Y. Tang , Olga Bandman , Bridget Warren , Cynthia Honchell , Dyung Lu , Kavitha Thangavelu , Sally Lee , Yuming Xu , Junming Yang , Preeti Lal , Bao Tran , Craig Ison , Brendan Duggan , Stephanie Sapperstein
CPC分类号: C12N15/1055 , A61K39/3955 , A61K47/64 , A61K47/643 , A61K2039/505 , C07K14/47 , C07K14/4711 , C07K14/4713 , C07K16/18 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/622 , C07K2317/75 , C07K2317/76 , G01N33/5023
摘要: The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
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公开(公告)号:US20050033018A1
公开(公告)日:2005-02-10
申请号:US10477714
申请日:2002-05-16
申请人: Preeti Lal , Bridget Warren , Yuming Xu , Brendan Duggan , Cynthia Honchell , Deborah Kallick , Mariah Baughn , Y. Tang , Henry Yue , Olga Bandman , Karen Jones , Shanya Becha , Uyen Tran , Janice Au-Young , Jennifer Griffin , Yeganeh Zebarjadian , Ernestie Lee , Vicki Elliott , Kavitha Thangavelu , Jayalaxmi Ramkumar , Yan Lu , April Hafalia , Narinder Chawla , Craig Ison , Michael Thornton , Anita Swarnakar , Junming Yang , Thomas Richardson , Brooke Emerling , Monique Yao , Benjamin Cocks , Bharati Sanjanwala , Patricia Mason , Ameena Gandhi , Joana Li , Rajagopal Gururajan , Kimberly Gietzen , Ian Forsythe
发明人: Preeti Lal , Bridget Warren , Yuming Xu , Brendan Duggan , Cynthia Honchell , Deborah Kallick , Mariah Baughn , Y. Tang , Henry Yue , Olga Bandman , Karen Jones , Shanya Becha , Uyen Tran , Janice Au-Young , Jennifer Griffin , Yeganeh Zebarjadian , Ernestie Lee , Vicki Elliott , Kavitha Thangavelu , Jayalaxmi Ramkumar , Yan Lu , April Hafalia , Narinder Chawla , Craig Ison , Michael Thornton , Anita Swarnakar , Junming Yang , Thomas Richardson , Brooke Emerling , Monique Yao , Benjamin Cocks , Bharati Sanjanwala , Patricia Mason , Ameena Gandhi , Joana Li , Rajagopal Gururajan , Kimberly Gietzen , Ian Forsythe
IPC分类号: G01N33/50 , A61K45/00 , A61K49/00 , A61P1/00 , A61P3/00 , A61P25/00 , A61P29/00 , A61P31/12 , A61P35/00 , A61P37/06 , C07K14/47 , C07K14/705 , C07K16/28 , C07K16/46 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/02 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/02 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , C07H21/04
CPC分类号: C07K14/705 , C07K14/47
摘要: The invention provides human receptors and membrane-associated proteins (REMAP) and polynucleotides which identify and encode REMAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.
摘要翻译: 本发明提供鉴定和编码REMAP的人受体和膜相关蛋白(REMAP)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与REMAP的异常表达相关的紊乱的方法。
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