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18 条记录 (耗时 0.016 秒)

    DEVICES, SYSTEMS, AND METHODS FOR A REDUCER WITH AN INTEGRATED SEAL
    3.
    发明申请
    DEVICES, SYSTEMS, AND METHODS FOR A REDUCER WITH AN INTEGRATED SEAL 有权

    公开(公告)号：US20230058593A1

    公开(公告)日：2023-02-23

    申请号：US18048874

    申请日：2022-10-24

    申请人： Repligen Corporation

    发明人： Derek Carroll ,  Bao Le

    IPC分类号： F16L25/14 ,  F16L21/03

    摘要： The present disclosure is related to bioprocessing devices, systems, and methods, and particularly to sanitary connections for bioprocessing. The devices, systems, and methods described herein can relate to the sanitary connection of flow fittings, such as reducers, with considerations for ease of assembly and sealing. In some embodiments, the system may include a flow reducer, a ferrule and a gasket. The flow reducer may include a gasket channel, an overmold channel within the gasket channel, and one or more cavities within the overmold channel. The gasket may be overmolded within the gasket channel and extending within the one or more cavities.

    Devices, systems, and methods for a reducer with an integrated seal
    4.
    发明授权
    Devices, systems, and methods for a reducer with an integrated seal 有权

    公开(公告)号：US11519539B2

    公开(公告)日：2022-12-06

    申请号：US16666970

    申请日：2019-10-29

    申请人： Repligen Corporation

    发明人： Derek Carroll ,  Bao Le

    IPC分类号： F16L25/14 ,  F16L21/03

    摘要： The present disclosure is related to bioprocessing devices, systems, and methods, and particularly to sanitary connections for bioprocessing. The devices, systems, and methods described herein can relate to the sanitary connection of flow fittings, such as reducers, with considerations for ease of assembly and sealing. In some embodiments, the system may include a flow reducer, a ferrule and a gasket. The flow reducer may include a gasket channel, an overmold channel within the gasket channel, and one or more cavities within the overmold channel. The gasket may be overmolded within the gasket channel and extending within the one or more cavities.

    VARIABLE PATHLENGTH UV SPECTROSCOPY BASED AUTOMATED TFF SYSTEM
    6.
    发明公开
    VARIABLE PATHLENGTH UV SPECTROSCOPY BASED AUTOMATED TFF SYSTEM 审中-公开

    公开(公告)号：US20230294021A1

    公开(公告)日：2023-09-21

    申请号：US18123917

    申请日：2023-03-20

    申请人： Repligen Corporation

    发明人： Ramsey Shanbaky ,  Dodd Weisenberger ,  Derek Carroll ,  Paul Lalo ,  Brandon Goldberg

    IPC分类号： B01D29/90 ,  G01N15/06

    CPC分类号： B01D29/908 ,  G01N15/06 ,  G01N21/33

    摘要： A system for TFF filtration of a feedstock includes a feed vessel containing a solution comprising a target biomolecule, a filter membrane for filtering the solution, a feed pump for moving the solution from the feed vessel to the filter membrane, a buffer vessel coupled to the feed vessel by a buffer supply line, and a diafiltration pump disposed in the buffer supply line for delivering a buffer solution to the feed vessel. A variable path-length instrument is coupled to the feed line for determining, in real time, a concentration of the target biomolecule in the solution. A controller is coupled to the variable path-length instrument, the feed pump, and the diafiltration pump to control operation of the system based on the received information.