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公开(公告)号：US20180319903A1
公开(公告)日：2018-11-08
申请号：US15767958
申请日：2016-10-14
Applicant: Roquette Freres
Inventor： Xavier Parissaux , Jean-Baptiste Palmieri , Mathias Ibert , Clothilde Buffe
IPC: C08B37/16 , C08L5/16 , A61K31/4965 , A61K47/69 , A61K31/724
CPC classification number: C08B37/0012 , A61K31/4965 , A61K31/724 , A61K47/40 , A61K47/6951 , C08B37/0015 , C08L5/16 , C08L2201/06 , C08L2203/02
Abstract: The invention relates to a novel methylated cyclodextrin and to a novel method used for the production thereof. The invention also relates to the use of said methylated cyclodextrin for the solubilisation of lipophilic compounds, or carriers of at least one lipophilic group. The invention further relates to a composition comprising said methylated cyclodextrin, particularly a pharmaceutical composition.
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公开(公告)号：US10022392B2
公开(公告)日：2018-07-17
申请号：US15039864
申请日：2014-12-12
Applicant: ROQUETTE FRERES
Inventor： Marc Salome , Daniel Wils , Xavier Parissaux , François Mach , Fabrizio Montecucco
IPC: A61K31/724 , A61K45/06
Abstract: The invention relates to a novel use of a pharmaceutical composition comprising at least one methyl cyclodextrin having a molar substitution (MS) degree of between 0.05 and 1.5 in the treatment and/or prevention of diseases that can be treated and/or prevented by an increase in the HDL cholesterol level. The invention also relates to the use thereof in the treatment and/or prevention of atherosclerosis or complications relating to an atheroma, and/or diseases of the central nervous system. The pharmaceutical compositions of the invention can also be used to stimulate the reduction of circulating fatty acid and triglyceride levels and to reduce or prevent atheromatous plaques.
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公开(公告)号：US11266680B2
公开(公告)日：2022-03-08
申请号：US15903738
申请日：2018-02-23
Applicant: Roquette Freres
Inventor： Marc Salome , Daniel Wils , Xavier Parissaux , Francois Mach , Fabrizio Montecucco
IPC: A61K31/724 , A61K45/06
Abstract: Pharmaceutical composition and their uses are disclosed, the composition comprising at least one methyl cyclodextrin having a molar substitution (MS) degree of between 0.05 and 1.5 in the treatment and/or prevention of diseases that can be treated and/or prevented by an increase in the HDL cholesterol level.
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公开(公告)号：US11098135B2
公开(公告)日：2021-08-24
申请号：US15767958
申请日：2016-10-14
Applicant: Roquette Freres
Inventor： Xavier Parissaux , Jean-Baptiste Palmieri , Mathias Ibert , Clothilde Buffe
IPC: C08B37/16 , A61K47/40 , A61K47/69 , A61K31/4965 , A61K31/724 , C08L5/16
Abstract: The invention relates to a novel methylated cyclodextrin and to a novel method used for the production thereof. The invention also relates to the use of said methylated cyclodextrin for the solubilisation of lipophilic compounds, or carriers of at least one lipophilic group. The invention further relates to a composition comprising said methylated cyclodextrin, particularly a pharmaceutical composition.
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公开(公告)号：US11033504B2
公开(公告)日：2021-06-15
申请号：US16055815
申请日：2018-08-06
Applicant: ROQUETTE FRERES
Inventor： Xavier Parissaux , Gregory Le Bihan , Sebastien Croquet
IPC: A61K9/28 , A23P20/00 , A23L27/30 , C09D103/08 , A61K36/31
Abstract: The invention relates to a film-forming composition comprising a fluidised hydroxypropyl starch and sorbitol, and to a film-coating method using said composition. The invention further relates to film-coated solid forms comprising a fluidised hydroxypropyl starch and sorbitol in the coating.
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公开(公告)号：US20180207198A1
公开(公告)日：2018-07-26
申请号：US15903738
申请日：2018-02-23
Applicant: Roquette Freres
Inventor： Marc Salome , Daniel Wils , Xavier Parissaux , Francois Mach , Fabrizio Montecucco
IPC: A61K31/724 , A61K45/06
CPC classification number: A61K31/724 , A61K45/06
Abstract: Pharmaceutical composition and their uses are disclosed, the composition comprising at least one methyl cyclodextrin having a molar substitution (MS) degree of between 0.05 and 1.5 in the treatment and/or prevention of diseases that can be treated and/or prevented by an increase in the HDL cholesterol level.
