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公开(公告)号：US20060210440A1
公开(公告)日：2006-09-21
申请号：US11391743
申请日：2006-03-29
IPC分类号： G01N27/00
CPC分类号： G01N21/7703 , G01N21/1702
摘要： A system that includes a device is provided in which the device includes a piezoelectric substrate; a sensor layer disposed on the substrate and operable to interact with, or react with, a target species; a first and a second electrode that are spaced from each other and in communication with the substrate; a first detector operable to detect the interaction or the reaction of the sensor layer with the target species based on a change in an optical characteristic of electromagnetic radiation propagated through the substrate; and a second detector operable to acoustically detect the interaction or the reaction of the sensor layer with the target species. Associated methods are provided.
摘要翻译： 提供一种包括装置的系统，其中所述装置包括压电基板; 传感器层，其设置在所述基板上并且可操作以与目标物种相互作用或与目标物质反应; 第一和第二电极，彼此间隔开并与衬底连通; 第一检测器，其可操作以基于传播通过所述衬底的电磁辐射的光学特性的变化来检测所述传感器层与所述目标物质的相互作用或反应; 以及第二检测器，其可操作以声学地检测传感器层与目标物种的相互作用或反应。 提供相关方法。
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公开(公告)号：US20060198760A1
公开(公告)日：2006-09-07
申请号：US11391744
申请日：2006-03-29
CPC分类号： G01N21/1702
摘要： A device that includes a piezoelectric substrate is provided. The device may include a sensor layer disposed on the substrate and operable to interact with, or react with, a target species; a first and a second electrode, that are spaced from each other and in communication with the substrate; a first detector operable to detect the interaction or the reaction of the sensor layer with the target species based on a change in an optical characteristic of electromagnetic radiation propagated through the substrate; and a second detector operable to acoustically detect the interaction or the reaction of the sensor layer with the target species. Associated methods are provided.
摘要翻译： 提供了包括压电基板的装置。 该装置可以包括设置在基板上并且可操作以与目标物种相互作用或与目标物质反应的传感器层; 第一和第二电极，彼此间隔开并与衬底连通; 第一检测器，其可操作以基于传播通过所述衬底的电磁辐射的光学特性的变化来检测所述传感器层与所述目标物质的相互作用或反应; 以及第二检测器，其可操作以声学地检测传感器层与目标物种的相互作用或反应。 提供相关方法。
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3.发明申请Material compositions for sensors for determination of chemical species at trace concentrations and method of using sensors 有权用于测定微量浓度的化学物质的传感器的材料组成和使用传感器的方法公开(公告)号：US20070092973A1
公开(公告)日：2007-04-26
申请号：US11259506
申请日：2005-10-26
申请人： Radislav Potyrailo , Timothy Sivavec , Caibin Xiao , Theodore Cecconie , Lamyaa Hassib , Andrew Leach , David Engel
发明人： Radislav Potyrailo , Timothy Sivavec , Caibin Xiao , Theodore Cecconie , Lamyaa Hassib , Andrew Leach , David Engel
IPC分类号： G01N21/00
CPC分类号： G01N31/22 , G01N21/78 , Y10S436/80 , Y10S436/805
摘要： A method of quantitatively measuring the concentration of a chemical species in a sample solution with a sensor film. A hydrogel sensor film is prepared having a chemical composition comprising an indicator that changes its optical property in the ultra-violet, visible or near-infrared spectral range upon being exposed to the chemical species in the sample solution. The film is exposed to a fixed amount of the sample solution. The concentration of the chemical species in the sample solution is quantified using the average absorbance measured from the sensor film.
摘要翻译： 用传感器膜定量测定样品溶液中化学物质浓度的方法。 制备水凝胶传感器膜，其具有化学组成，该化学组成包括在暴露于样品溶液中的化学物质时在紫外线，可见光或近红外光谱范围内改变其光学性质的指示剂。 将该膜暴露于固定量的样品溶液。 使用从传感器膜测量的平均吸光度来量化样品溶液中化学物质的浓度。
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公开(公告)号：US08587410B2
公开(公告)日：2013-11-19
申请号：US13145172
申请日：2010-01-28
申请人： Radislav Potyrailo , Vincent F. Pizzi , Hanno Ehring , Cheryl M. Surman , Klaus Gebauer , Mircea Georgescu
发明人： Radislav Potyrailo , Vincent F. Pizzi , Hanno Ehring , Cheryl M. Surman , Klaus Gebauer , Mircea Georgescu
IPC分类号： G06K7/01
CPC分类号： G06K19/07749 , A61M39/10 , A61M39/18 , A61M2205/3331 , A61M2205/6054 , B65B55/08 , G06K19/07798 , G06Q20/3278
摘要： This invention provides a system for operating RFID tags on a single-use connector. The system includes: a first single-use connector configured to receive a first RFID tag and a second single-use connector configured to receive a second RFID tag. The invention also includes a reader placed close to the first RFID tag and the second RFID tag. The reader is configured to: determine if the first RFID tag and the second RFID tag are gamma sterilized; determine if the first RFID tag and the second RFID tag were previously used; determine if the first RFID tag and the second RFID tag are authentic; and determine if the first RFID tag matches with the second RFID tag.
摘要翻译： 本发明提供一种用于在一次性连接器上操作RFID标签的系统。 该系统包括：被配置为接收第一RFID标签的第一单用连接器和被配置为接收第二RFID标签的第二单用连接器。 本发明还包括靠近第一RFID标签和第二RFID标签放置的读取器。 读取器被配置为：确定第一RFID标签和第二RFID标签是否被伽马灭菌; 确定先前使用的第一RFID标签和第二RFID标签; 确定第一RFID标签和第二RFID标签是否是真实的; 并且确定第一RFID标签是否与第二RFID标签匹配。
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公开(公告)号：US20070092975A1
公开(公告)日：2007-04-26
申请号：US11507689
申请日：2006-08-22
IPC分类号： G01N21/77
CPC分类号： G01N21/78 , B01L3/502715 , B01L3/502723 , B01L3/50273 , B01L3/502746 , B01L2200/0605 , B01L2200/0642 , B01L2300/0806 , B01L2300/0816 , B01L2300/0864 , B01L2300/087 , B01L2400/0406 , B01L2400/0427 , B01L2400/0448 , G01N21/80 , G01N35/00069 , G01N2021/7766 , G01N2021/7773 , G01N2021/7783 , G01N2021/7786 , G01N2021/7793 , Y10T436/144444 , Y10T436/25 , Y10T436/2575
摘要： Total analysis systems and methods for simultaneously monitoring a suite of biological and/or chemical species in water and/or other process systems are disclosed. The system provides a sample-volume controlled sensor array comprising a fluid delivery device and a plurality of optical sensor elements for determining the presence and total concentrations of multiple analytes in the process system simultaneously. Delivery means are provided to deliver a metered quantity of sample fluid to the sensor array. Image identification algorithms are provided for identifying the analytes based on image intensity, color pattern, positional arrangement, and the like. The methods incorporate multivariate optimization algorithms to analyze multiple sensor responses. This produces analytical results that are typically difficult to obtain without full system or variable compensation. The improved array response may then be utilized to measure, monitor, and control the concentration of analytes in the chemical or biological sample or water system.
摘要翻译： 公开了用于在水和/或其它工艺系统中同时监测一套生物和/或化学物质的总分析系统和方法。 该系统提供了一个样品量控制的传感器阵列，其包括流体输送装置和多个光学传感器元件，用于同时确定过程系统中多个分析物的存在和总浓度。 提供输送装置以将计量的样品流体传送到传感器阵列。 提供图像识别算法，用于基于图像强度，颜色图案，位置排列等来识别分析物。 该方法结合了多变量优化算法来分析多个传感器响应。 这产生的分析结果通常难以在没有完整系统或可变补偿的情况下获得。 然后可以使用改进的阵列响应来测量，监测和控制化学或生物样品或水系统中分析物的浓度。
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6.发明申请Optical sensor array system and method for parallel processing of chemical and biochemical information 有权光学传感器阵列系统和化学和生化信息并行处理方法公开(公告)号：US20070092407A1
公开(公告)日：2007-04-26
申请号：US11259643
申请日：2005-10-26
申请人： Caibin Xiao , Radislav Potyrailo , William Morris , Scott Boyette , LiJie Yu , Theodore Cecconie , Andrew Leach , Prashant Shrikhande
发明人： Caibin Xiao , Radislav Potyrailo , William Morris , Scott Boyette , LiJie Yu , Theodore Cecconie , Andrew Leach , Prashant Shrikhande
CPC分类号： G01N21/78 , B01L3/50273 , B01L3/502746 , B01L2200/0621 , B01L2300/0803 , B01L2300/0816 , B01L2300/0864 , B01L2400/0406 , B01L2400/088 , G01N21/253 , G01N21/80 , G01N31/22 , Y10T137/7036
摘要： Total analysis systems and methods for simultaneously monitoring a suite of biological and/or chemical species in water and/or other process systems are disclosed. The system provides a sample-volume controlled sensor array comprising a fluid delivery device and a plurality of optical sensor elements for determining the presence and total concentrations of multiple analytes in the process system simultaneously. Image identification algorithms are provided for identifying the analytes based on image intensity, color pattern, positional arrangement, and the like. The methods incorporate multivariate optimization algorithms to analyze multiple sensor responses. This produces analytical results that are typically difficult to obtain without full system or variable compensation. The improved array response may then be utilized to measure, monitor, and control the concentration of analytes in the chemical or biological sample or water system.
摘要翻译： 公开了用于在水和/或其它工艺系统中同时监测一套生物和/或化学物质的总分析系统和方法。 该系统提供了一个样品量控制的传感器阵列，其包括流体输送装置和多个光学传感器元件，用于同时确定过程系统中多个分析物的存在和总浓度。 提供图像识别算法，用于基于图像强度，颜色图案，位置排列等来识别分析物。 该方法结合了多变量优化算法来分析多个传感器响应。 这产生的分析结果通常难以在没有完整系统或可变补偿的情况下获得。 然后可以利用改进的阵列响应来测量，监测和控制化学或生物样品或水系统中分析物的浓度。
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公开(公告)号：US20060138079A1
公开(公告)日：2006-06-29
申请号：US11021399
申请日：2004-12-27
CPC分类号： B29C35/0894 , B01J2219/00286 , B01J2219/00378 , B01J2219/00387 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00657 , B01J2219/00659 , B01L3/5027 , B29L2031/756
摘要： A method for making a microfluidic device comprises providing a processing substrate, forming a negative stamp on the processing substrate using a direct write process, disposing a coating material on the processing substrate, curing the coating material to produce a cured coating material, and separating the processing substrate and the negative stamp from the cured coating material, wherein a plurality of channels are formed in the cured coating material corresponding to a location of the negative stamp.
摘要翻译： 一种制造微流体装置的方法包括：提供处理基板，使用直接写入工艺在处理基板上形成负印模，在处理基板上设置涂层材料，固化涂层材料以产生固化涂层材料， 处理基板和来自固化涂层材料的负印模，其中在对应于负印模的位置的固化涂层材料中形成多个通道。
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公开(公告)号：US20060033325A1
公开(公告)日：2006-02-16
申请号：US10889913
申请日：2004-07-13
CPC分类号： G11B23/281 , Y10S428/913 , Y10S428/916 , Y10S428/917 , Y10T428/2982 , Y10T428/31507 , Y10T428/31663 , Y10T436/13
摘要： An authenticatable article can comprise a polymer layer comprising a first taggant, and a second taggant disposed adjacent to the first taggant. The relative relationship of the first taggant and the second taggant can be such that at least one of the first taggant and the second taggant can cause an alteration in an emission from the other of the first taggant and the second taggant. One method of authenticating an article comprises illuminating an article and determining if an altered emission is within a selected emission range. The article comprises a polymer layer and a coating disposed on a side of the polymer layer. The polymer layer comprises a first taggant, and the coating causes a predetermined alteration in an emission from the taggant to form the altered emission.
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9.发明申请Sensor system and methods for improved quantitation of environmental parameters 失效传感器系统和改进环境参数定量的方法公开(公告)号：US20050111328A1
公开(公告)日：2005-05-26
申请号：US10952635
申请日：2004-09-29
申请人： Radislav Potyrailo , William Morris , Andrew Leach
发明人： Radislav Potyrailo , William Morris , Andrew Leach
CPC分类号： G01N21/5907 , B01J2219/00536 , B01J2219/00689 , B01J2219/00702 , B01L3/502715 , B01L3/545 , B01L2300/024 , B01L2300/0806 , G01N35/00069
摘要： A system and method employing optical disk drives for quantitative analysis of chemical and biochemical parameters, in which sensor materials disposed on an optical disk are responsive to physical, chemical, biochemical, and other parameters in the environment. The light interacts with the sensor materials when the light propagates through the sensor material, reflects off the optical media's reflective layer, and propagates back through the sensor region. The interacted light is captured by a photodetector, which outputs a response analog signal, for example, an analog voltage signal, which is indicative of a condition of the environment to which the sensor materials have been exposed. The system includes software algorithms which cause the laser source and optical detector to move to a specified location or logical block address of the disk, measure the optical signal during disk rotation, display a map of the sensor material response, and reduce the noise level in the measured signal.
摘要翻译： 一种使用光盘驱动器进行化学和生物化学参数的定量分析的系统和方法，其中设置在光盘上的传感器材料响应于环境中的物理，化学，生物化学和其它参数。 当光传播通过传感器材料时，光与传感器材料相互作用，从光学介质的反射层反射并传播回传感器区域。 相互作用的光被光电检测器捕获，光电检测器输出响应模拟信号，例如模拟电压信号，其表示传感器材料暴露于的环境的状况。 该系统包括使激光源和光学检测器移动到盘的指定位置或逻辑块地址的软件算法，在盘旋转期间测量光信号，显示传感器材料响应的映射，并降低噪声水平 测量信号。
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公开(公告)号：US20050095715A1
公开(公告)日：2005-05-05
申请号：US10605862
申请日：2003-10-31
CPC分类号： C09K11/02 , C09K11/06 , C09K11/08 , Y10T436/13
摘要： A polymer comprising a tagging material is provided wherein the tagging material comprises at least one organic fluorophore dye, or at least one inorganic fluorophore, or at least one organometallic fluorophore, or at least one semi-conducting luminescent nanoparticle, or combination thereof, wherein the tagging material has a temperature stability of at least about 350° C. and is present in a sufficient quantity such that the tagging material is detectible via a spectrofluorometer at an excitation wavelength in a range between about 100 nanometers and about 1100 nanometers. Further embodiments of the present invention include a method for identifying a polymer and an article comprising a polymer wherein the polymer contains the aforementioned tagging material.
摘要翻译： 提供了包含标签材料的聚合物，其中标签材料包含至少一种有机荧光团染料或至少一种无机荧光团，或至少一种有机金属荧光团，或至少一种半导体发光纳米颗粒或其组合，其中 标签材料具有至少约350℃的温度稳定性并且以足够的量存在，使得标记材料可以通过分光荧光计在约100纳米至约1100纳米的范围内的激发波长处检测。 本发明的其它实施方案包括用于鉴定聚合物的方法和包含聚合物的制品，其中聚合物含有上述标记材料。
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