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13 条记录 (耗时 0.026 秒)

    Method for producing cellulose derivatives
    1.
    发明授权
    Method for producing cellulose derivatives 失效
    纤维素衍生物的制造方法

    公开(公告)号：US6146858A

    公开(公告)日：2000-11-14

    申请号：US462046

    申请日：2000-02-14

    申请人： Rainhardt Koch ,  Frank Berendes ,  John Foster ,  Hans-Georg Rast ,  Jurgen Engelhardt ,  Jorg Neubauer ,  Wolfgang Koch ,  Klaus Szablikowski

    发明人： Rainhardt Koch ,  Frank Berendes ,  John Foster ,  Hans-Georg Rast ,  Jurgen Engelhardt ,  Jorg Neubauer ,  Wolfgang Koch ,  Klaus Szablikowski

    IPC分类号： C08B1/00 ,  C08B11/08 ,  C12P19/14 ,  C12S3/04 ,  C12P19/04 ,  C08B1/06 ,  C12N9/26 ,  C12N9/42 ,  D06M16/00

    CPC分类号： C12P19/14 ,  C08B1/00 ,  C08B11/08

    摘要： Samples of commercial cellulose having high crystallinity (>80%) and a degree of polymerization of approximately 1500 were pretreated enzymatically under various conditions with commercial endoglucanases, before the chemical conversion to substituted cellulose derivatives was carried out. The enzymatically pretreated cellulose samples exhibited a significantly higher substitution, up to 222% higher, in comparison with control samples which had been treated with buffer without enzyme. The increase in substitution during the chemical reaction could be observed in the presence of various amounts of alkali, but fell as the amounts of alkali decreased. At the same degree of substitution of the cellulose derivative, the use of cellulose pretreated with endoglucanase significantly reduced the amount of alkali required by 60%, as compared with the use of cellulose pretreated only with buffer. Furthermore, by reducing the amount of water used in the reaction mixture in the chemical reaction, it was possible further to increase the substitution of enzymatically pretreated cellulose.

    摘要翻译： PCT No.PCT / EP98 / 03907 Sec。 371日期2000年2月14日 102（e）日期2000年2月14日PCT提交1998年6月26日PCT公布。 出版物WO99 /​​ 02568 日期1999年1月21日在进行取代纤维素衍生物的化学转化之前，将具有高结晶度（> 80％）和聚合度约1500的市售纤维素样品在各种条件下用商业内切葡聚糖酶预处理。 与没有酶的缓冲液处理的对照样品相比，酶法预处理的纤维素样品显示出高得多的222％的替代。 化学反应中取代的增加可以在各种碱存在下观察到，但随着碱量的降低而降低。 与纤维素衍生物相同的取代度，与仅使用缓冲液预处理的纤维素的使用相比，使用用内切葡聚糖酶预处理的纤维素显着地减少了所需碱量的60％。 此外，通过减少化学反应中反应混合物中使用的水量，可以进一步增加酶预处理的纤维素的取代。

    Plant-treatment agents
    3.
    发明授权
    Plant-treatment agents 失效
    植物处理剂

    公开(公告)号：US06191071B1

    公开(公告)日：2001-02-20

    申请号：US09297628

    申请日：1999-05-04

    申请人： Joachim Simon ,  Hanns Peter Müller ,  Uwe Priesnitz ,  Hans-Georg Rast

    发明人： Joachim Simon ,  Hanns Peter Müller ,  Uwe Priesnitz ,  Hans-Georg Rast

    IPC分类号： A01N2510

    CPC分类号： A01N25/10

    摘要： The invention concerns novel plant-treatment agents comprising: at least one thermoplastically processable biodegradable polyester amide, optionally in a mixture with one or a plurality of further thermoplastically processable, biodegradable polymer components; at least one agrochemical substance; and optionally additives. The invention further concerns a process for preparing these agents, and their use in the application of agrochemical substances.

    摘要翻译： 本发明涉及新颖的植物处理剂，其包括：至少一种热塑性可加工的可生物降解的聚酯酰胺，任选地与一种或多种另外的热塑性可加工的可生物降解的聚合物组分的混合物; 至少一种农用化学物质; 和任选的添加剂。 本发明还涉及制备这些试剂的方法及其在应用农药物质中的应用。

    Possibly substituted 8-cyano-1-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]-nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolin carboxylic acids and their derivatives
    4.
    发明授权
    Possibly substituted 8-cyano-1-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]-nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolin carboxylic acids and their derivatives 有权
    可取代的8-氰基-1-环丙基-7-（2,8-二氮杂双环[4.3.0] - 壬烷-8-基）-6-氟-1,4-二氢-4-氧代-3-喹啉羧酸 酸及其衍生物

    公开(公告)号：US06323213B1

    公开(公告)日：2001-11-27

    申请号：US09125191

    申请日：1998-08-13

    申请人： Stefan Bartel ,  Thomas Jaetsch ,  Thomas Himmler ,  Hans-Georg Rast ,  Werner Hallenbach ,  Ernst Heinen ,  Franz Pirro ,  Martin Scheer ,  Michael Stegemann ,  Hans-Peter Stupp ,  Heinz-Georg Wetzstein

    发明人： Stefan Bartel ,  Thomas Jaetsch ,  Thomas Himmler ,  Hans-Georg Rast ,  Werner Hallenbach ,  Ernst Heinen ,  Franz Pirro ,  Martin Scheer ,  Michael Stegemann ,  Hans-Peter Stupp ,  Heinz-Georg Wetzstein

    IPC分类号： A61K31407

    CPC分类号： C07D471/04 ,  A01N43/90

    摘要： The present invention relates to novel optionally substituted 8-cyano-1-cyclo-propyl-7-(2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids and their derivatives, of the general formula (I) in which R1 represents hydrogen, C1-C4-alkyl which is optionally substituted by hydroxyl, methoxy, amino, methylamino or dimethylamino, or (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl, R2 represents hydrogen, benzyl, C1-C3-alkyl, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl, radicals having the structures —CH═CH—COOR3, —CH2CH2COOR3, —CH2CH2CN, —CH2CH2COCH3 or —CH2COCH3, in which R3 represents methyl or ethyl, or a radical of the general structure R4—(NH—CHR5—CO)n—, in which R4 represents hydrogen, C1-C3-alkyl or the radical —COO-tert-butyl, R5 represents hydrogen, C1-C4-alkyl, hydroxyalkyl, aminoalkyl, thioalkyl, carboxyalkyl or benzyl and n is 1 or 2, and Y is oxygen or sulfur, the process for their preparation and their use in antibacterial compositions.

    摘要翻译： 本发明涉及新的任选取代的8-氰基-1-环丙基-7-（2,8-二氮杂双环[4.3.0]壬烷-8-基）-6-氟-1,4-二氢-4- 甲氧基，氨基，甲基氨基或二甲基氨基取代的C 1 -C 4 - 烷基，或（5-甲基-2-羟基喹啉羧酸）或其衍生物，其中R 1表示氢， 氧代-1,3-二氧杂环戊烯-4-基）甲基，R 2表示氢，苄基，C 1 -C 3 - 烷基，（5-甲基-2-氧代-1,3-二氧杂环戊烯-4-基）甲基， 结构-CH = CH-COOR 3，-CH 2 CH 2 COOR 3，-CH 2 CH 2 CN，-CH 2 CH 2 COCH 3或-CH 2 COCH 3，其中R 3表示甲基或乙基，或通式结构R4-（NH-CHR5-CO）n - 的基团，其中R4 代表氢，C 1 -C 3 - 烷基或-COO-叔丁基，R 5表示氢，C 1 -C 4 - 烷基，羟基烷基，氨基烷基，硫代烷基，羧基烷基或苄基，n是1或2，Y是氧或硫， 其制备方法及其在抗菌组合物中的应用。

    Method and device for detecting biologically active substances
    7.
    发明授权
    Method and device for detecting biologically active substances 失效
    用于检测生物活性物质的方法和装置

    公开(公告)号：US07695900B2

    公开(公告)日：2010-04-13

    申请号：US11711560

    申请日：2007-02-27

    申请人： Wolfgang Kreiss ,  Guenther Eberz ,  Hans-Georg Rast ,  Claus Weisemann

    发明人： Wolfgang Kreiss ,  Guenther Eberz ,  Hans-Georg Rast ,  Claus Weisemann

    IPC分类号： C12Q1/00 ,  C12Q1/66

    CPC分类号： C12Q1/025 ,  C12Q1/04 ,  Y10S435/975

    摘要： This application claims a method for detecting biologically active substances, comprising the following steps a) providing a support carrying substances to be tested b) providing a suspension containing luminescent microorganisms, c) coating the support with the suspension of microorganisms, d) detecting the biologically active substances on the support by detecting the change in luminescence of the suspension of microorganisms, and e) stimulating the luminescence of the microorganisms before or during detection, and/or f) extending the period of luminescence of the microorganisms by employing substances for regulating and extending the period of luminescence of the microorganisms.

    摘要翻译： 本申请要求一种用于检测生物活性物质的方法，包括以下步骤：a）提供携带待测物质的载体b）提供含有发光微生物的悬浮液，c）用微生物悬浮液涂覆载体，d） 通过检测微生物悬浮液的发光变化，并且e）在检测前或检测期间刺激微生物的发光，和/或f）通过使用用于调节和调节微生物的物质来延长微生物的发光期 延长微生物的发光时间。

    Method and device for detecting biologically active substances
    8.
    发明授权
    Method and device for detecting biologically active substances 失效
    用于检测生物活性物质的方法和装置

    公开(公告)号：US07183113B2

    公开(公告)日：2007-02-27

    申请号：US10424067

    申请日：2003-04-25

    申请人： Wolfgang Kreiss ,  Guenther Eberz ,  Hans-Georg Rast ,  Claus Weisemann

    发明人： Wolfgang Kreiss ,  Guenther Eberz ,  Hans-Georg Rast ,  Claus Weisemann

    IPC分类号： G01N33/53

    CPC分类号： C12Q1/025 ,  C12Q1/04 ,  Y10S435/975

    摘要： The invention claimed herein is a kit for detecting biologically active substances on a support, comprising the luminescent marine bacteria Vibria Fischeri in a form stabilized for transport and storage, one or more cultivation media or the individual components of cultivation media for the microorganism wherein the cultivation media contains 100 mg/l to 500 mg/l of aspartic acid, and optionally additives for extending the period of luminescence selected from N-acylhomoserine lactones, dipeptides, oligopeptides, or their biochemical precursors, and boron compounds.

    摘要翻译： 本文所要求的发明是用于检测载体上的生物活性物质的试剂盒，其包含以稳定运输和储存的形式的发光海洋细菌Vibria Fischeri，一种或多种培养基或微生物培养基的各组分，其中培养 培养基含有100mg / l至500mg / l的天冬氨酸，以及任选的用于延长选自N-酰基高丝氨酸内酯，二肽，寡肽或其生化前体的发光期和硼化合物的添加剂。

    Method and device for detecting biologically active substances
    10.
    发明申请
    Method and device for detecting biologically active substances 失效
    用于检测生物活性物质的方法和装置

    公开(公告)号：US20070154978A1

    公开(公告)日：2007-07-05

    申请号：US11711560

    申请日：2007-02-27

    申请人： Wolfgang Kreiss ,  Gunther Eberz ,  Hans-Georg Rast ,  Claus Weisemann

    发明人： Wolfgang Kreiss ,  Gunther Eberz ,  Hans-Georg Rast ,  Claus Weisemann

    IPC分类号： C12Q1/18 ,  C12N1/20

    CPC分类号： C12Q1/025 ,  C12Q1/04 ,  Y10S435/975

    摘要： This application claims a method for detecting biologically active substances, comprising the following steps a) providing a support carrying substances to be tested b) providing a suspension containing luminescent microorganisms, c) coating the support with the suspension of microorganisms, d) detecting the biologically active substances on the support by detecting the change in luminescence of the suspension of microorganisms, and e) stimulating the luminescence of the microorganisms before or during detection, and/or f) extending the period of luminescence of the microorganisms by employing substances for regulating and extending the period of luminescence of the microorganisms.

    摘要翻译： 本申请要求一种用于检测生物活性物质的方法，包括以下步骤：a）提供携带待测物质的载体b）提供含有发光微生物的悬浮液，c）用微生物悬浮液涂覆载体，d） 通过检测微生物悬浮液的发光变化，并且e）在检测前或检测期间刺激微生物的发光，和/或f）通过使用用于调节和调节微生物的物质来延长微生物的发光期 延长微生物的发光时间。