公开(公告)号：US07186839B2

公开(公告)日：2007-03-06

申请号：US10332105

申请日：2001-06-14

申请人： Raymond Vincent Heavon Jones ,  Joanne Emma Murray ,  Jennifer Ann White ,  Alastair Iain Currie Stewart ,  Susan Thomson Hamilton ,  Alan John Whitton ,  Julie Forrester

发明人： Raymond Vincent Heavon Jones ,  Joanne Emma Murray ,  Jennifer Ann White ,  Alastair Iain Currie Stewart ,  Susan Thomson Hamilton ,  Alan John Whitton ,  Julie Forrester

IPC分类号： A61K31/44 ,  A61K31/47 ,  A61K31/428 ,  C07D215/18 ,  C07D213/61 ,  C07D277/68

CPC分类号： C07D213/64 ,  C07D215/227 ,  C07D277/68

摘要： A process for extracting from aqueous solution the alkali metal or calcium salt of a halo or haloalkyl substituted 2-hydroxypyridine, or a 2-hydroxyquinoline or 2-hydroxybenzothiazole which comprises contacting an aqueous alkaline or neutral solution of the alkali metal or calcium salt, in which is dissolved an alkali metal fluoride, chloride, bromide, hydroxide, sulphate, sulphite, cyanate, cyanide, thiocyanate, thiosulphate, sulphide, phosphate, hydrogen phosphate, carbonate, bicarbonate, borate, chlorate, hypochlorite, perchlorate, nitrite, chromate, dichromate or permanganate or calcium chloride, bromide, nitrate, nitrite, chlorate, hypochlorite, perchlorate, thiocyanate, thiosulphate, chromate, dichtromate or permanganate, with a partially water-miscible organic solvent so as to transfer aqueous solution of the alkali metal or calcium salt of the 2-hydroxypyridine, 2-hydroxyquinoline or 2-hydroxybenzothiasole into the solvent whilst retaining separate aqueous and solvent phases, and thereafter separating the solvent phase containing the alkali metal or calcium salt and water from the aqueous phase, the ratio of solvent to water in the separated solvent phase being from 0.5:1 to 10:1 w/w.

摘要翻译： 从水溶液中提取卤素或卤代烷基取代的2-羟基吡啶或2-羟基喹啉或2-羟基苯并噻唑的碱金属盐或钙盐的方法，其包括使碱金属或钙盐的碱性或中性水溶液与 溶解碱金属氟化物，氯化物，溴化物，氢氧化物，硫酸盐，亚硫酸盐，氰酸盐，氰化物，硫氰酸盐，硫代硫酸盐，硫化物，磷酸盐，磷酸氢盐，碳酸盐，碳酸氢盐，硼酸盐，氯酸盐，次氯酸盐，高氯酸盐，亚硝酸盐，铬酸盐，重铬酸盐 或高锰酸盐或氯化钙，溴化物，硝酸盐，亚硝酸盐，氯酸盐，次氯酸盐，高氯酸盐，硫氰酸盐，硫代硫酸盐，铬酸盐，二铬酸盐或高锰酸盐，与部分水混溶性有机溶剂混合，以将碱金属或钙盐的水溶液 2-羟基吡啶，2-羟基喹啉或2-羟基苯并噻吩进入溶剂，同时保留分开的水相和溶剂相， 然后从水相中分离出含有碱金属或钙盐和水的溶剂相，溶剂相中的溶剂相与水的比例为0.5:1至10:1w / w。

公开(公告)号：US07371324B2

公开(公告)日：2008-05-13

申请号：US10332107

申请日：2001-06-14

申请人： Raymond Vincent Heavon Jones ,  Joanne Emma Murray ,  Jennifer Ann White ,  Barry Stuart Crombie ,  James Samuel Shane Rountree ,  Jacqueline Ann Campbell

发明人： Raymond Vincent Heavon Jones ,  Joanne Emma Murray ,  Jennifer Ann White ,  Barry Stuart Crombie ,  James Samuel Shane Rountree ,  Jacqueline Ann Campbell

IPC分类号： B01D11/00

CPC分类号： C02F1/26 ,  C02F2101/34 ,  Y10S210/909

摘要： A process for extracting from aqueous solution the alkali metal or ammonium salt of a phenol, naphthol, anthrol or phenanthrol or the corresponding thiol, which comprises contacting an aqueous alkaline or neutral solution of the alkali metal or ammonium salt, in which is dissolved an alkali metal or ammonium fluoride, chloride, bromide, hydroxide, nitrate, nitrite, sulphate, sulphite, sulphide, thiosulphate, phosphate, hydrogen phosphate, carbonate, bicarbonate, cyanate, cyanide, thiocyanate, borate, chlorate, chlorite, hypochlorite, perchlorate, chromate, dichromate or permanganate, with a partially water-miscible organic solvent so as to transfer aqueous solution of the alkali metal or ammonium salt of the phenol, naphthol, anthrol or phenanthrol or corresponding thiol into the solvent while retaining separate aqueous and solvent phases, and thereafter separating the solvent phase containing the alkali metal or ammonium salt and water from the aqueous phase, the ratio of solvent to water in the separated solvent phase being from 0.5:1 to 10:1 w/w.

摘要翻译： 从水溶液中提取苯酚，萘酚，蒽或菲或其相应的硫醇的碱金属盐或铵盐的方法，该方法包括将碱金属盐或铵盐的碱性或中性水溶液与碱溶解的碱 硝酸盐，硫酸盐，硫酸盐，硫酸盐，硫酸盐，磷酸盐，磷酸盐，碳酸盐，碳酸氢盐，氰酸盐，氰化物，硫氰酸盐，硼酸盐，氯酸盐，亚氯酸盐，次氯酸盐，高氯酸盐，铬酸盐， 重铬酸盐或高锰酸盐，与部分水混溶的有机溶剂，以便将苯酚，萘酚，蒽酮或菲或菲硫醇的碱金属盐或铵盐的水溶液转移到溶剂中，同时保持分开的水相和溶剂相，之后 从水相中分离含有碱金属或铵盐和水的溶剂相，溶剂与w的比例 在分离的溶剂相中的比例为0.5:1至10:1w / w。