公开(公告)号：US20130061343A1

公开(公告)日：2013-03-07

申请号：US13577281

申请日：2011-02-08

申请人： Rene Hen ,  Kenji Tanaka

发明人： Rene Hen ,  Kenji Tanaka

IPC分类号： C12N15/85 ,  C12P19/34 ,  C12N5/10

CPC分类号： C07H21/00 ,  A01K67/0275 ,  A01K2217/072 ,  A01K2217/075 ,  A01K2217/203 ,  A01K2217/206 ,  A01K2227/105 ,  C12N15/85 ,  C12N15/8509 ,  C12N2800/107 ,  C12N2800/30 ,  C12N2830/003

摘要： Disclosed is a FAST (Flexible Accelerated STOP TetO-knockin) system, an efficient method for manipulating gene expression in vivo to rapidly screen animal models of disease. This invention further discloses a single gene targeting event yielding 2 distinct knockin mice—STOP-tetO and tetO knockin—which permit generation of multiple strains with variable expression patterns: 1) knockout, 2) Cre-mediated rescue; 3) tTA-mediated misexpression; 4) tTA-mediated overexpression; and 5) tTS-mediated conditional knockout/knockdown. Using the FAST system, multiple gain- and loss-of-function strains can therefore be generated on a timescale not previously achievable. These strains can then be screened for clinically-relevant abnormalities. The flexibility and broad applicability of the FAST system is demonstrated by targeting several genes encoding proteins implicated in neuropsychiatric disorders: Mlc1, Neuroligin 3, the serotonin 1A receptor, and the serotonin 1B receptor.

摘要翻译： 公开了一种FAST（Flexible Accelerated STOP TetO-knockin）系统，其是在体内操纵基因表达以快速筛选动物疾病模型的有效方法。 本发明进一步公开了产生2个不同敲入小鼠-STAT-tetO和tetO敲入物的单一基因靶向事件，其允许产生具有可变表达模式的多个菌株：1）敲除，2）Cre介导的营救; 3）tTA介导的错误表达; 4）tTA介导的过度表达; 和5）tTS介导的条件敲除/击倒。 因此，使用FAST系统，可以在以前不能实现的时间范围内生成多个功能损失增益和损失。 然后可以筛选这些菌株用于临床相关的异常。 FAST系统的灵活性和广泛适用性通过靶向编码与神经精神障碍相关的蛋白质的几种基因来证明：Mlc1，神经丝氨酸3，5-羟色胺1A受体和血清素1B受体。

公开(公告)号：US08852930B2

公开(公告)日：2014-10-07

申请号：US13577281

申请日：2011-02-08

申请人： Rene Hen ,  Kenji Tanaka

发明人： Rene Hen ,  Kenji Tanaka

IPC分类号： C12N15/00 ,  C12N5/00 ,  C07H21/00 ,  A01K67/027 ,  C12N15/85

CPC分类号： C07H21/00 ,  A01K67/0275 ,  A01K2217/072 ,  A01K2217/075 ,  A01K2217/203 ,  A01K2217/206 ,  A01K2227/105 ,  C12N15/85 ,  C12N15/8509 ,  C12N2800/107 ,  C12N2800/30 ,  C12N2830/003

摘要： Disclosed is a FAST (Flexible Accelerated STOP TetO-knockin) system, an efficient method for manipulating gene expression in vivo to rapidly screen animal models of disease. This invention further discloses a single gene targeting event yielding 2 distinct knockin mice—STOP-tetO and tetO knockin—which permit generation of multiple strains with variable expression patterns: 1) knockout, 2) Cre-mediated rescue; 3) tTA-mediated misexpression; 4) tTA-mediated overexpression; and 5) tTS-mediated conditional knockout/knockdown. Using the FAST system, multiple gain- and loss-of-function strains can therefore be generated on a timescale not previously achievable. These strains can then be screened for clinically-relevant abnormalities. The flexibility and broad applicability of the FAST system is demonstrated by targeting several genes encoding proteins implicated in neuropsychiatric disorders: Mlc1, Neuroligin 3, the serotonin 1A receptor, and the serotonin 1B receptor.

摘要翻译： 公开了一种FAST（Flexible Accelerated STOP TetO-knockin）系统，其是在体内操纵基因表达以快速筛选动物疾病模型的有效方法。 本发明进一步公开了产生2个不同敲入小鼠-STAT-tetO和tetO敲入物的单一基因靶向事件，其允许产生具有可变表达模式的多个菌株：1）敲除，2）Cre介导的营救; 3）tTA介导的错误表达; 4）tTA介导的过度表达; 和5）tTS介导的条件敲除/击倒。 因此，使用FAST系统，可以在以前不能实现的时间范围内生成多个功能损失增益和损失。 然后可以筛选这些菌株用于临床相关的异常。 FAST系统的灵活性和广泛适用性通过靶向编码与神经精神障碍相关的蛋白质的几种基因来证明：Mlc1，神经丝氨酸3，5-羟色胺1A受体和血清素1B受体。

公开(公告)号：US09361660B2

公开(公告)日：2016-06-07

申请号：US14118869

申请日：2012-05-15

申请人： Kenji Tanaka

发明人： Kenji Tanaka

IPC分类号： G06T1/00 ,  G06F3/00 ,  G06F3/01 ,  G06F3/0481

CPC分类号： G06T1/00 ,  G06F3/005 ,  G06F3/012 ,  G06F3/04815

摘要： An image-processing apparatus for generating images from a plurality of viewpoints comprises a supplementation section that receives images captured by a plurality of image capturing devices arranged on a predetermined plane and generates supplemental images at a plurality of supplemental camera positions on the predetermined plane, each supplemental image being generated based on images captured by a predetermined number of the image capturing devices on the predetermined plane; and a viewpoint image generation section that generates a viewpoint image from a viewpoint by selecting pixels from the plurality of supplemental images and captured images.

摘要翻译： 一种用于从多个视点生成图像的图像处理装置包括补充部分，其接收由布置在预定平面上的多个图像捕获装置拍摄的图像，并且在预定平面上的多个补充相机位置处产生补充图像，每个补充图像 基于在预定平面上由预定数量的图像捕获装置捕获的图像生成补充图像; 以及视点图像生成部，其从多个补充图像和拍摄图像中选择像素，从视点生成视点图像。

公开(公告)号：US09224536B2

公开(公告)日：2015-12-29

申请号：US13568172

申请日：2012-08-07

申请人： Akira Kumada ,  Teruhisa Shibahara ,  Kenji Tanaka

发明人： Akira Kumada ,  Teruhisa Shibahara ,  Kenji Tanaka

IPC分类号： H01G5/00 ,  H01G7/00 ,  H01G7/06 ,  H01H57/00 ,  G01R27/26 ,  H01G5/16 ,  H03J3/20

CPC分类号： H01G5/16 ,  H03J3/20 ,  H03J2200/19

摘要： A variable capacitance device that achieves a desired capacitance even when factors causing varied capacitances are generated is configured such that a capacitance detection pulse signal is applied from a capacitance detection signal generation unit to a driving capacitor and a reference capacitor of a MEMS mechanical unit. The device voltage of the driving capacitor based on the capacitance detection signal and a driving voltage is applied to the inverting input terminal of a comparator. The device voltage of the reference capacitor based on the capacitance detection signal and the driving voltage is applied to the non-inverting input terminal of the comparator. The comparator generates a comparison output signal including “Hi” and “Low” values from the difference between these device voltages, and applies the output signal to a driving voltage generation unit. The driving voltage generation unit increases or decreases the driving voltage based on the comparison output signal.

摘要翻译： 即使产生导致变化的电容的因素，实现期望的电容的可变电容器件被配置为使得电容检测脉冲信号从电容检测信号生成单元施加到MEMS机械单元的驱动电容器和参考电容器。 基于电容检测信号的驱动电容器的器件电压和驱动电压被施加到比较器的反相输入端。 基于电容检测信号和驱动电压的参考电容器的器件电压被施加到比较器的非反相输入端。 比较器从这些器件电压之间的差产生包括“Hi”和“Low”值的比较输出信号，并将输出信号施加到驱动电压产生单元。 驱动电压产生单元根据比较输出信号来增大或减小驱动电压。

公开(公告)号：US09099757B2

公开(公告)日：2015-08-04

申请号：US13224574

申请日：2011-09-02

申请人： Kenji Tanaka ,  Kazuaki Matsuo ,  Kazuhide Tozuka ,  Kazuya Okabe

发明人： Kenji Tanaka ,  Kazuaki Matsuo ,  Kazuhide Tozuka ,  Kazuya Okabe

IPC分类号： H01M10/05 ,  H01M4/64 ,  H01M10/0587 ,  H01M4/36 ,  H01M2/16 ,  H01M2/14 ,  H01M4/13 ,  H01M4/66

CPC分类号： H01M10/0587 ,  H01M2/145 ,  H01M2/1646 ,  H01M4/13 ,  H01M4/366 ,  H01M4/664 ,  H01M4/667 ,  Y02E60/122

摘要： Provided is a battery which has less tendency to experience delamination or loss of short circuit prevention layer and/or active material layer during manufacture and use.A battery comprising a laminated electrode assembly in which a positive electrode, a negative electrode, and a separator are laminated together; wherein an alumina-containing layer containing γ-alumina particles is formed on at least one species selected from among the group consisting of the positive electrode, the negative electrode, and the separator. The fact that alumina-containing layer(s) is or are made to contain γ-alumina particles makes it possible to obtain high bond strength between alumina-containing layer(s) and electrode(s) comprising metal(s), current collector(s) and/or active material(s) making up electrode(s), and/or separator(s).

摘要翻译： 提供一种电池，其在制造和使用期间具有较少的体验分层或失去防短路层和/或活性材料层的倾向。 包括层叠电极组件的电池，其中正电极，负电极和隔板层压在一起; 其中在选自正极，负极和隔膜中的至少一种物质上形成含有γ-氧化铝颗粒的含氧化铝层。 含有氧化铝的层或含有γ-氧化铝颗粒的事实使得可以获得含氧化铝层和包含金属，集电体（...）的电极之间的高粘合强度， s）和/或组成电极的活性材料和/或分离器。

公开(公告)号：US09061485B2

公开(公告)日：2015-06-23

申请号：US13703858

申请日：2011-06-01

申请人： Hiroyuki Kurimura ,  Tomoyuki Kanai ,  Isamu Ichikawa ,  Gosuke Nakajima ,  Hayato Miyazaki ,  Yasunori Hayashi ,  Kenji Tanaka

发明人： Hiroyuki Kurimura ,  Tomoyuki Kanai ,  Isamu Ichikawa ,  Gosuke Nakajima ,  Hayato Miyazaki ,  Yasunori Hayashi ,  Kenji Tanaka

IPC分类号： B32B37/02 ,  B32B17/10

CPC分类号： B32B37/02 ,  B32B17/10036 ,  B32B17/10706 ,  B32B17/10816 ,  Y10T156/1044

摘要： Provided is a method for manufacturing a translucent rigid substrate laminate which can improve a thickness precision while decreasing the risk of fractures. In the method for manufacturing a translucent rigid substrate laminate according to the present invention, translucent rigid substrates are placed opposite to each other such that bonding surfaces thereof are parallel to each other, both rigid substrates are brought toward each other while being kept parallel, the both rigid substrates are preliminarily bonded using a photo-curable fixing agent, the bonded translucent rigid substrates are roll-pressed, and the fixing agent is then cured.

摘要翻译： 提供一种半导体刚性基板层叠体的制造方法，能够提高厚度精度，同时降低断裂的风险。 在根据本发明的半导体刚性基板层压体的制造方法中，半透明刚性基板彼此相对设置，使得其接合表面彼此平行，两个刚性基板彼此保持平行， 使用光固化固定剂预先粘合两个刚性基材，将粘合的半透明刚性基材进行辊压，然后固化固化剂。

公开(公告)号：US08924636B2

公开(公告)日：2014-12-30

申请号：US13609991

申请日：2012-09-11

申请人： Takashi Hirao ,  Hirokuni Yano ,  Aurelien Nam Phong Tran ,  Mitsunori Tadokoro ,  Hiroki Matsudaira ,  Tatsuya Sumiyoshi ,  Yoshimi Niisato ,  Kenji Tanaka

发明人： Takashi Hirao ,  Hirokuni Yano ,  Aurelien Nam Phong Tran ,  Mitsunori Tadokoro ,  Hiroki Matsudaira ,  Tatsuya Sumiyoshi ,  Yoshimi Niisato ,  Kenji Tanaka

IPC分类号： G06F12/10 ,  G06F12/02

CPC分类号： G06F12/0246 ,  G06F12/1009 ,  G06F2212/1032 ,  G06F2212/7201 ,  G11C16/349

摘要： A management information generating method wherein logical and physical block addresses (BAs) of continuous addresses are associated with each other in the BA translation table. When a logical block is constructed, a value is set for a maximum number of allowable defective physical blocks. A logical block having fewer defects than the set number is set usable, and a logical block having more defects than the set number is set unusable. System logical block construction is performed to preferentially select physical blocks from a plane list including a large number of usable blocks to equalize the number of usable blocks in each plane list. It is determined whether the number of free blocks is insufficient on the basis of a first management unit and whether the storage area for the indicated capacity can be reserved on the basis of the management unit different from the first unit.

摘要翻译： 一种管理信息生成方法，其中连续地址的逻辑和物理块地址（BA）在BA转换表中彼此相关联。 当构建逻辑块时，为允许的有缺陷的物理块的最大数量设置一个值。 具有比设定号码少的缺陷的逻辑块被设置为可用，并且具有比设定号码多的缺陷的逻辑块被设置为不可用。 执行系统逻辑块构造以从包括大量可用块的平面列表中优先选择物理块以均衡每个平面列表中的可用块的数量。 基于第一管理单元确定空闲块的数量是否不足，以及是否可以基于与第一单元不同的管理单元来保留指示容量的存储区域。

公开(公告)号：US08685249B2

公开(公告)日：2014-04-01

申请号：US13131769

申请日：2009-08-07

申请人： Kazuhisa Takeuchi ,  Yoshiaki Ito ,  Kenji Tanaka ,  Hideo Iwahashi ,  Katsunori Matsui ,  Takayoshi Hori

发明人： Kazuhisa Takeuchi ,  Yoshiaki Ito ,  Kenji Tanaka ,  Hideo Iwahashi ,  Katsunori Matsui ,  Takayoshi Hori

IPC分类号： B01D65/06 ,  B01D61/12 ,  C02F1/76 ,  C02F1/70 ,  B01D61/58

CPC分类号： C02F1/441 ,  B01D61/022 ,  B01D61/025 ,  B01D61/12 ,  B01D2311/14 ,  B01D2317/025 ,  C02F2103/08 ,  C02F2209/03 ,  C02F2301/08 ,  Y02A20/131

摘要： A high-pressure pump P1 that increases the pressure of raw water, a high-pressure reverse osmosis device including a high-pressure reverse osmosis membrane for concentrating a salt content in high-pressure feed water, a first drain valve mounted on a permeated water line for supplying the permeated water downstream and temporarily draining permeated water of an initial start-up from a discharge line, a low-pressure pump that is mounted on a permeated water line provided downstream of the first drain valve and reduces the pressure of the permeated water, a low-pressure reverse osmosis device including a low-pressure reverse osmosis membrane for concentrating a salt content in low-pressure feed water, and a second drain valve mounted on a discharge line at the concentrated water side of the low-pressure reverse osmosis device that temporarily discharges the low-pressure feed water of the initial start-up supplied to the low-pressure reverse osmosis device.

摘要翻译： 一种提高原水压力的高压泵P1，包括用于浓缩高压给水中的盐含量的高压反渗透膜的高压反渗透装置，安装在渗透水上的第一排水阀 用于向下游供应渗透水的管线，并且从排放管线暂时排出初始启动的渗透水;安装在设置在第一排水阀下游的渗透水管线上的低压泵，并且减少渗透的压力 水，低压反渗透装置，其包括用于浓缩低压给水中的盐含量的低压反渗透膜和安装在低压反相浓缩水侧的排出管路上的第二排水阀 渗透装置，其临时排出供给到低压反渗透装置的初始启动的低压给水。

公开(公告)号：US20130335532A1

公开(公告)日：2013-12-19

申请号：US14002829

申请日：2012-03-02

申请人： Kenji Tanaka ,  Yoshihiro Takahashi ,  Kazumasa Tanaka

发明人： Kenji Tanaka ,  Yoshihiro Takahashi ,  Kazumasa Tanaka

IPC分类号： G06T7/00

CPC分类号： G06T7/593 ,  G01B11/00 ,  G06T2207/10012

摘要： The present disclosure is directed to an apparatus and a method for generating an image. A plurality of image capturing devices capture images including objects reflected by a curved mirror from predetermined angles. Image units included in a captured image are analyzed; and a distance for an object included in the captured images is determined according to the analyzing result.

摘要翻译： 本公开涉及用于生成图像的装置和方法。 多个图像捕获装置从预定角度捕获包括由反射镜反射的物体的图像。 分析拍摄图像中包含的图像单位; 并且根据分析结果确定包括在所捕获的图像中的对象的距离。

公开(公告)号：US20130271557A1

公开(公告)日：2013-10-17

申请号：US13883481

申请日：2011-10-28

申请人： Yoshinaga Kato ,  Kenji Tanaka ,  Shizu Kanauchi ,  Masaki Nakagawa ,  Alain Volmat ,  Takahiro Asai

发明人： Yoshinaga Kato ,  Kenji Tanaka ,  Shizu Kanauchi ,  Masaki Nakagawa ,  Alain Volmat ,  Takahiro Asai

IPC分类号： H04N7/15

CPC分类号： H04N7/15 ,  H04M1/2535 ,  H04M2250/52 ,  H04M2250/62 ,  H04N5/44513 ,  H04N7/142 ,  H04N7/147

摘要： A communication terminal receives display data for displaying certain data on a screen of a display device and image data of an optical-to-electrical-converted image from another communication terminal via a communication network, includes a storage part storing reception information indicating whether the display data has been received by the communication terminal and arrangement information indicating at least one of a size and a position of the image based on the image data, in a manner of associating with one another; a reception part receiving the display data and the image data; an extraction part extracting, based on the reception information, the corresponding arrangement information from the storage part; and a display control part displaying the image using the image data based on the arrangement information extracted by the extraction part.

摘要翻译： 通信终端经由通信网络从另一通信终端接收用于在显示装置的屏幕上显示特定数据的显示数据和来自另一通信终端的光电转换图像的图像数据，包括存储指示显示器 数据已被通信终端接收，并且以相互关联的方式基于图像数据指示图像的大小和位置中的至少一个的排列信息; 接收显示数据和图像数据的接收部分; 提取部分，基于所述接收信息，从所述存储部分提取相应的布置信息; 以及显示控制部，其基于由所述提取部提取的配置信息，使用所述图像数据来显示所述图像。