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    Method and apparatus for automatically characterizing a malignancy
    1.
    发明申请
    Method and apparatus for automatically characterizing a malignancy 有权
    用于自动表征恶性肿瘤的方法和装置

    公开(公告)号：US20070167697A1

    公开(公告)日：2007-07-19

    申请号：US11291830

    申请日：2005-11-30

    申请人： Ricardo Avila ,  Floribertus Jansen ,  Dinko Trotter ,  James Miller ,  Ravindra Manjeshwar ,  Thomas Sebastian

    发明人： Ricardo Avila ,  Floribertus Jansen ,  Dinko Trotter ,  James Miller ,  Ravindra Manjeshwar ,  Thomas Sebastian

    IPC分类号： A61B5/05

    CPC分类号： G01T1/1611 ,  A61B6/037 ,  A61B34/10 ,  G01R33/4808 ,  G01R33/481 ,  G01R33/4812 ,  G01R33/4814

    摘要： A malignancy probability is automatically calculated for one or more lesions. The malignancy probability is based on assessments of one or more malignancy characteristics for each lesion derived from two or more structural and/or functional image data sets. Likewise, in some embodiments, the malignancy probability is based on assessments of one or more malignancy characteristics for each lesion derived from a combination of structural and functional image data. In one embodiment, the set of structural image data is a set of CT image data and the set of functional image data is a set of PET image data. The one or more lesions may be detected in the structural and/or functional image data by automated routines or by a visual inspection by a clinician or other reviewer.

    摘要翻译： 自动计算一个或多个病变的恶性概率。 恶性概率基于从两个或多个结构和/或功能图像数据集导出的每个病变的一个或多个恶性特征的评估。 类似地，在一些实施例中，恶性概率基于从结构和功能图像数据的组合导出的每个损伤的一个或多个恶性特征的评估。 在一个实施例中，该组结构图像数据是一组CT图像数据，并且功能图像数据集合是一组PET图像数据。 在结构和/或功能图像数据中可以通过自动程序或临床医生或其他审查者的目视检查来检测一个或多个损伤。

    Method and apparatus for automatically characterizing a malignancy
    2.
    发明授权
    Method and apparatus for automatically characterizing a malignancy 有权
    用于自动表征恶性肿瘤的方法和装置

    公开(公告)号：US08010184B2

    公开(公告)日：2011-08-30

    申请号：US11291830

    申请日：2005-11-30

    申请人： Ricardo Avila ,  Floribertus Heukensfeldt Jansen ,  Dinko Gonzalez Trotter ,  James Miller ,  Ravindra Manjeshwar ,  Thomas Sebastian

    发明人： Ricardo Avila ,  Floribertus Heukensfeldt Jansen ,  Dinko Gonzalez Trotter ,  James Miller ,  Ravindra Manjeshwar ,  Thomas Sebastian

    IPC分类号： A61B5/055

    CPC分类号： G01T1/1611 ,  A61B6/037 ,  A61B34/10 ,  G01R33/4808 ,  G01R33/481 ,  G01R33/4812 ,  G01R33/4814

    摘要： A region of interest is automatically evaluated. The automatic evaluation is based on assessments of one or more characteristics. The one or more characteristics of the region of interest are assessed in a plurality of image data sets acquired by a respective plurality of imaging modalities. In some embodiments, the evaluation is based on assessments of one or more characteristics for each region of interest derived from a combination of structural and functional image data. In one embodiment, the set of structural image data is a set of CT image data and the set of functional image data is a set of PET image data. The one or more lesions may be detected in the structural and/or functional image data by automated routines or by a visual inspection by a clinician or other reviewer.

    摘要翻译： 自动评估感兴趣的区域。 自动评估是基于一个或多个特征的评估。 在由相应的多个成像模式获取的多个图像数据集中评估感兴趣区域的一个或多个特征。 在一些实施例中，评估基于从结构和功能图像数据的组合导出的每个感兴趣区域的一个或多个特征的评估。 在一个实施例中，该组结构图像数据是一组CT图像数据，并且功能图像数据集合是一组PET图像数据。 在结构和/或功能图像数据中可以通过自动程序或临床医生或其他审查者的目视检查来检测一个或多个损伤。

    METHOD AND SYSTEM FOR CALIBRATING A TIME OF FLIGHT POSITRON EMISSION TOMOGRAPHY SYSTEM
    4.
    发明申请
    METHOD AND SYSTEM FOR CALIBRATING A TIME OF FLIGHT POSITRON EMISSION TOMOGRAPHY SYSTEM 有权
    用于校准飞行姿势排放测量系统时间的方法和系统

    公开(公告)号：US20070057189A1

    公开(公告)日：2007-03-15

    申请号：US11226171

    申请日：2005-09-14

    申请人： Floribertus Jansen ,  Ravindra Manjeshwar

    发明人： Floribertus Jansen ,  Ravindra Manjeshwar

    IPC分类号： G01T1/161

    CPC分类号： G01T1/2985

    摘要： A method and system for calibrating a Time of Flight Positron Emission Tomography (TOF PET) system are provided. The method includes storing acquired scan data from detector pairs. The acquired scan data includes image data and timing information. The method further includes reconstructing images using scan data. The method also includes determining a timing correction for each detector based on intensity distribution histograms of emission sources. The system includes a controller, which is configured to perform the above-mentioned method steps.

    摘要翻译： 提供了一种用于校准飞行时间正电子发射断层扫描（TOF PET）系统的方法和系统。 该方法包括从检测器对存储获取的扫描数据。 获取的扫描数据包括图像数据和定时信息。 该方法还包括使用扫描数据重建图像。 该方法还包括基于发射源的强度分布直方图确定每个检测器的定时校正。 该系统包括控制器，其被配置为执行上述方法步骤。

    Nuclear medicine imaging system and method using multiple types of imaging detectors
    5.
    发明授权
    Nuclear medicine imaging system and method using multiple types of imaging detectors 有权
    核医学成像系统和使用多种成像检测器的方法

    公开(公告)号：US08575555B2

    公开(公告)日：2013-11-05

    申请号：US13077540

    申请日：2011-03-31

    申请人： Kristen Ann Wangerin ,  Evren Asma ,  Jorge Uribe ,  Ravindra Manjeshwar

    发明人： Kristen Ann Wangerin ,  Evren Asma ,  Jorge Uribe ,  Ravindra Manjeshwar

    IPC分类号： G01T1/166

    CPC分类号： G01T1/166 ,  A61B6/037 ,  G01T1/1603 ,  G01T1/1644 ,  G01T1/249

    摘要： A Nuclear Medicine (NM) imaging system and method using multiple types of imaging detectors are provided. One NM imaging system includes a gantry, at least a first imaging detector coupled to the gantry, wherein the first imaging detector is a non-moving detector, and at least a second imaging detector coupled to the gantry, wherein the second imaging detector is a moving detector. The first imaging detector is larger than the second imaging detector and the first and second imaging detectors have different detector configurations. The NM imaging system further includes a controller configured to control the operation of the first and second imaging detectors during an imaging scan of an object to acquire Single Photon Emission Computed Tomography (SPECT) image information such that at least the first imaging detector remains stationary with respect to the gantry during image acquisition.

    摘要翻译： 提供了使用多种成像检测器的核医学（NM）成像系统和方法。 一个NM成像系统包括台架，至少第一成像检测器，其耦合到台架，其中第一成像检测器是非移动检测器，以及耦合到台架的至少第二成像检测器，其中第二成像检测器是 移动探测器。 第一成像检测器大于第二成像检测器，并且第一和第二成像检测器具有不同的检测器配置。 NM成像系统还包括控制器，其被配置为在对象的成像扫描期间控制第一和第二成像检测器的操作，以获取单光子发射计算机断层扫描（SPECT）图像信息，使得至少第一成像检测器保持静止， 在图像采集期间对台架的尊重。

    Method and system for calibrating a time of flight positron emission tomography system
    6.
    发明申请
    Method and system for calibrating a time of flight positron emission tomography system 失效
    校准飞行时间正电子发射断层扫描系统的方法和系统

    公开(公告)号：US20070205368A1

    公开(公告)日：2007-09-06

    申请号：US11786951

    申请日：2007-04-13

    申请人： Floribertus Heukensfeldt Jansen ,  Ravindra Manjeshwar

    发明人： Floribertus Heukensfeldt Jansen ,  Ravindra Manjeshwar

    IPC分类号： G01T1/161

    CPC分类号： G01T1/2985

    摘要： A method and system for calibrating a time of flight (TOF) positron emission tomography (PET) scanner are provided. The method stores acquired scan data from detector pairs including data and timing information. The method further calculates an intensity distribution of emission sources based on the scan data and defines a timing pivot point based on a median of an intensity histogram. The method determines a timing correction for each detector based on the location of the timing pivot point. The positron emission tomography (PET) system further provides a plurality of detectors, used in performing imaging scans, and a processor. The processor is configured to determine a timing correction for each detector.

    摘要翻译： 提供了一种用于校准飞行时间（TOF）正电子发射断层摄影（PET）扫描仪的方法和系统。 该方法存储来自检测器对的获取的扫描数据，包括数据和定时信息。 该方法还基于扫描数据计算发射源的强度分布，并且基于强度直方图的中值来定义定时枢轴点。 该方法基于定时枢轴点的位置确定每个检测器的定时校正。 正电子发射断层摄影（PET）系统还提供用于执行成像扫描的多个检测器和处理器。 处理器被配置为确定每个检测器的定时校正。

    NUCLEAR MEDICINE IMAGING SYSTEM AND METHOD USING MULTIPLE TYPES OF IMAGING DETECTORS
    7.
    发明申请
    NUCLEAR MEDICINE IMAGING SYSTEM AND METHOD USING MULTIPLE TYPES OF IMAGING DETECTORS 有权
    核医学成像系统和使用多种成像检测器的方法

    公开(公告)号：US20120248320A1

    公开(公告)日：2012-10-04

    申请号：US13077540

    申请日：2011-03-31

    申请人： Kristen Ann Wangerin ,  Evren Asma ,  Jorge Uribe ,  Ravindra Manjeshwar

    发明人： Kristen Ann Wangerin ,  Evren Asma ,  Jorge Uribe ,  Ravindra Manjeshwar

    IPC分类号： G01T1/166

    CPC分类号： G01T1/166 ,  A61B6/037 ,  G01T1/1603 ,  G01T1/1644 ,  G01T1/249

    摘要： A Nuclear Medicine (NM) imaging system and method using multiple types of imaging detectors are provided. One NM imaging system includes a gantry, at least a first imaging detector coupled to the gantry, wherein the first imaging detector is a non-moving detector, and at least a second imaging detector coupled to the gantry, wherein the second imaging detector is a moving detector. The first imaging detector is larger than the second imaging detector and the first and second imaging detectors have different detector configurations. The NM imaging system further includes a controller configured to control the operation of the first and second imaging detectors during an imaging scan of an object to acquire Single Photon Emission Computed Tomography (SPECT) image information such that at least the first imaging detector remains stationary with respect to the gantry during image acquisition.

    摘要翻译： 提供了使用多种成像检测器的核医学（NM）成像系统和方法。 一个NM成像系统包括台架，至少第一成像检测器，其耦合到台架，其中第一成像检测器是非移动检测器，以及耦合到台架的至少第二成像检测器，其中第二成像检测器是 移动探测器。 第一成像检测器大于第二成像检测器，并且第一和第二成像检测器具有不同的检测器配置。 NM成像系统还包括控制器，其被配置为在对象的成像扫描期间控制第一和第二成像检测器的操作，以获取单光子发射计算机断层扫描（SPECT）图像信息，使得至少第一成像检测器保持静止， 在图像采集期间对台架的尊重。

    METHOD AND SYSTEM FOR IMAGING USING A FILTER FOR TIME-OF-FLIGHT PET
    10.
    发明申请
    METHOD AND SYSTEM FOR IMAGING USING A FILTER FOR TIME-OF-FLIGHT PET 失效
    使用过滤器进行成像的方法和系统

    公开(公告)号：US20060102846A1

    公开(公告)日：2006-05-18

    申请号：US10988878

    申请日：2004-11-15

    申请人： Ravindra Manjeshwar ,  Charles Stearns

    发明人： Ravindra Manjeshwar ,  Charles Stearns

    IPC分类号： G01T1/164

    CPC分类号： G06T11/005

    摘要： Methods and systems for imaging by using a filter for Time-Of-Flight Positron Emission Tomography (TOF PET) are described. The described methods of imaging a patient by using a positron emission tomography (PET) system includes acquiring a plurality of frames of sinogram data, filtering the acquired sinogram data and back-projecting the filtered sinogram data to form an output image of the patient. The acquired sinogram data defines a line of response (LOR) and a time-of-flight (TOF) measurement that localizes positron annihilation within the patient. The filtering of the acquired sinogram data is performed using the TOF measurement.

    摘要翻译： 描述了使用飞行时间正电子发射断层扫描（TOF PET）的滤波器进行成像的方法和系统。 所描述的通过使用正电子发射断层摄影（PET）系统对患者进行成像的方法包括获取正弦图数据的多个帧，对所获取的正弦图数据进行滤波，以及反投影过滤的正弦图数据以形成患者的输出图像。 获得的正中图数据定义了定位在患者体内的正电子湮灭的响应线（LOR）和飞行时间（TOF）测量。 使用TOF测量来执行所获取的正弦图数据的滤波。