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公开(公告)号:US08765677B2
公开(公告)日:2014-07-01
申请号:US13497363
申请日:2010-09-21
申请人: Richard Lewis , David John Adams , Geza Berecki , Roger Drinkwater , Paul Francis Alewood , MacDonald James Christie
发明人: Richard Lewis , David John Adams , Geza Berecki , Roger Drinkwater , Paul Francis Alewood , MacDonald James Christie
IPC分类号: A61K38/16 , C07K14/00 , A61P35/00 , A61P9/12 , A61P29/00 , A61P1/00 , A61P13/00 , A61P25/18 , A61P25/04
CPC分类号: C07K14/43504 , A61K38/00
摘要: This invention relates to an isolated, synthetic or recombinant peptide, wherein the peptide comprises the sequence: C K G K G A Xaa1 C R Xaa2 Xaa3 Xaa4 Y Xaa5 C C Xaa6 G Xaa7 C R Xaa8 Xaa9 R C SEQ ID NO: 1 wherein Xaa1, Xaa3, Xaa4, Xaa6, Xaa7 and Xaa8 are independently selected from serine and threonine; Xaa2 is selected from arginine and lysine; Xaa5 is selected from aspartic acid and glutamic acid; and Xaa9 is selected from glycine, alanine, valine, leucine and isoleucine.
摘要翻译: 本发明涉及一种分离的,合成的或重组的肽,其中肽包含序列:CKGKGA Xaa1 CR Xaa2 Xaa3 Xaa4 Y Xaa5 CC Xaa6 G Xaa7 CR Xaa8 Xaa9 RC SEQ ID NO:1其中Xaa1,Xaa3,Xaa4,Xaa6,Xaa7 Xaa8独立地选自丝氨酸和苏氨酸; Xaa2选自精氨酸和赖氨酸; Xaa5选自天冬氨酸和谷氨酸; 并且Xaa9选自甘氨酸,丙氨酸,缬氨酸,亮氨酸和异亮氨酸。
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公开(公告)号:US4049856A
公开(公告)日:1977-09-20
申请号:US689251
申请日:1976-05-24
申请人: David John Adams
发明人: David John Adams
CPC分类号: F02F11/002 , B32B15/06 , F16J15/123 , Y10T29/49297 , Y10T428/24273 , Y10T428/24281 , Y10T428/24314 , Y10T428/25 , Y10T428/252 , Y10T428/31641 , Y10T428/31652 , Y10T428/31656 , Y10T428/31696 , Y10T428/31707
摘要: This invention relates to a metal-cored asbestos-rubber gasket wherein openings are formed in the gasket with the openings being defined by eyelets. The eyelets have flanges which engage the facing layers of the gasket and normal cracking of the eyelets incipient to incorporation thereof in the gasket is prevented by incorporating in the facing layer material microspheres in a sufficient amount to permit crushing thereof by the eyelet flanges under pressure.
摘要翻译: 本发明涉及一种金属芯石棉橡胶垫片,其中开口形成在垫圈中,开口由孔眼限定。 孔眼具有与垫圈的相对的层接合的凸缘,并且通过在足够的面积层材料微球中加入足以使其在压力下被孔眼凸缘破碎的方式来防止初始化到其中的孔眼的正常开裂。
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