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1.发明授权System to monitor temperature near an invasive device during magnetic resonance procedures 失效在磁共振程序期间监测侵入性装置附近的温度的系统
公开(公告)号：US5730134A
公开(公告)日：1998-03-24
申请号：US714840
申请日：1996-09-09
CPC分类号： A61B5/01 , A61B5/055 , G01R33/287 , G01R33/4804
摘要： A temperature monitoring system employs a temperature detection means incorporated into an invasive device intended to be placed within a body during a magnetic resonance procedure. The temperature monitoring system is used to monitor temperature rises in tissue arising from the creation of electric fields within the tissue. These electric fields are created by the application of RF pulses during the course of a magnetic resonance procedure which induce electrical current in the invasive device. It the detected temperature rise exceeds a selected threshold, the temperature monitoring system can cause the magnetic resonance imaging system to either reduce RF power or terminate the procedure. An optical coupling may be used between the imaging or tracking RF coil and the MR receiver to eliminate heating induced by the application of RF pulses during the procedure.
摘要翻译： 温度监测系统采用将温度检测装置并入到旨在在磁共振程序期间放置在体内的侵入性装置中。 温度监测系统用于监测组织内产生的电场产生的组织温度升高。 这些电场是通过在磁共振过程中施加RF脉冲而产生的，其在侵入性装置中引起电流。 检测到的温度上升超过选定的阈值，温度监测系统可以使磁共振成像系统降低RF功率或终止程序。 可以在成像或跟踪RF线圈和MR接收器之间使用光耦合器来消除在该过程期间由RF脉冲施加引起的加热。
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公开(公告)号：US5671739A
公开(公告)日：1997-09-30
申请号：US698700
申请日：1996-08-16
CPC分类号： A61B5/721 , A61B34/20 , A61B5/06 , A61B5/1135 , A61B8/0833 , A61B8/5276 , A61B2017/00694 , A61B5/7289
摘要： A tracking system monitors the position of a device within a subject and superimposes a graphic symbol on a diagnostic image of the subject. Registration of the tracked location with the diagnostic image is maintained in the presence of subject motion by monitoring subject motion and adjusting the display to compensate for subject motion. Motion monitoring can be performed with ultrasonic, optical or mechanical methods. The display can be adjusted by modifying the displayed location of the device or it can be adjusted by translating, rotating or distorting the diagnostic image.
摘要翻译： 跟踪系统监视对象内的设备的位置并将图形符号叠加在被摄体的诊断图像上。 通过监视对象运动并调整显示以补偿被摄体运动，通过诊断图像对被跟踪位置的注册保持在受试者运动的存在下。 运动监测可以用超声波，光学或机械方法进行。 可以通过修改显示的设备位置来调整显示，也可以通过翻译，旋转或扭曲诊断图像进行调整。
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公开(公告)号：US5882305A
公开(公告)日：1999-03-16
申请号：US954150
申请日：1997-10-20
CPC分类号： A61B5/01 , A61B5/055 , G01R33/287 , G01R33/4804
摘要： An optical coupling is incorporated into an invasive device used in magnetic resonance (MR) imaging. The coupling is incorporated into the invasive device between an imaging or tracking RF coil, and the MR receiver. The optical coupling has a first transducer circuit coupled to the RF which converts between optical and electrical signals. An optical fiber is coupled to the first transducer circuit and extends out of the invasive device to medical imaging equipment. Near this equipment, a second transducer circuit converts optical signals to electrical, and electrical signals to optical, just opposite that of the first transducer circuit. The present invention thereby replaces long lead wires which can cause heating during MR imaging, and may distort an MR image.
摘要翻译： 光耦合器被并入用于磁共振（MR）成像的侵入性装置中。 耦合结合到成像或跟踪RF线圈与MR接收器之间的侵入性装置中。 光耦合器具有耦合到RF的第一传感器电路，其在光信号和电信号之间进行转换。 光纤耦合到第一换能器电路，并且从侵入性装置延伸到医疗成像设备。 在该设备附近，第二传感器电路将光信号转换成电，并将电信号转换成与第一换能器电路相反的光信号。 因此，本发明代替在MR成像期间可能引起加热的长引线，并且可能使MR图像失真。
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公开(公告)号：US5730129A
公开(公告)日：1998-03-24
申请号：US415410
申请日：1995-04-03
CPC分类号： A61B5/1114 , A61B5/055 , A61B5/06 , A61B5/1127 , A61B5/1128 , G06T3/0006 , A61B5/7289
摘要： A tracking system monitors the position of a device within a subject and superimposes a graphic symbol on a diagnostic image of the subject. Registration of the tracked location with the diagnostic image is maintained in the presence of subject motion by monitoring subject motion and adjusting the display to compensate for subject motion. Motion monitoring can be performed with ultrasonic, optical or mechanical methods. The display can be adjusted by modifying the displayed location of the device or it can be adjusted by translating, rotating or distorting the diagnostic image.
摘要翻译： 跟踪系统监视对象内的设备的位置并将图形符号叠加在被摄体的诊断图像上。 通过监视对象运动并调整显示以补偿被摄体运动，通过诊断图像对被跟踪位置的注册保持在受试者运动的存在下。 运动监测可以用超声波，光学或机械方法进行。 可以通过修改显示的设备位置来调整显示，也可以通过翻译，旋转或扭曲诊断图像进行调整。
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5.发明授权
公开(公告)号：US5713359A
公开(公告)日：1998-02-03
申请号：US537575
申请日：1995-10-02
IPC分类号： A61B5/055
CPC分类号： A61B5/055
摘要： A magnetic resonance (MR) active invasive device system employs a small, high-field polarizing magnet, and a large low-field magnetic resonance (MR) imaging magnet for the purpose of generating MR images of blood perfusion in tissue. A subject is positioned in a large low-field MR imaging magnet. A catheter is inserted into the patient at or near the root of a vessel supplying blood to a portion of tissue to be imaged. A fluid, intended to be used as a contrast agent is first passed through the small high-field polarizing magnet, causing a high degree of net longitudinal magnetization to be produced in the fluid. The fluid is then introduced into the subject through the catheter. Radiofrequency (RF) pulses and magnetic field is gradients are then applied to the patient as in conventional MR imaging. Since the fluid has a larger longitudinal magnetization, before the MR imaging sequence, the fluid produces a much larger MR response signal than other tissue. Images acquired during periods of time in which the fluid is flowing and not flowing are mathematically combined to give an MR image whose pixel intensity is related to the degree of tissue perfusion.
摘要翻译： 磁共振（MR）有源侵入性装置系统采用小型高场极化磁体和大型低场磁共振（MR）成像磁体，以产生组织中血液灌注的MR图像。 受试者位于大型低场MR成像磁体中。 将导管插入到血管的根部处或附近，将血液供应到要成像的组织的一部分。 首先将用作造影剂的流体通过小型高场极化磁体，从而在流体中产生高度的净纵向磁化强度。 然后通过导管将流体引入受试者。 然后将射频（RF）脉冲和磁场梯度作为常规MR成像应用于患者。 由于流体具有较大的纵向磁化强度，在MR成像序列之前，流体产生比其它组织大得多的MR响应信号。 在流体流动并且不流动的时间段期间获取的图像在数学上被组合以给出其像素强度与组织灌注程度相关的MR图像。
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公开(公告)号：US07725157B2
公开(公告)日：2010-05-25
申请号：US11383608
申请日：2006-05-16
申请人： Charles Lucian Dumoulin , Richard Philip Mallozzi , Robert David Darrow , Harvey Ellis Cline , Renee Ann Guhde
发明人： Charles Lucian Dumoulin , Richard Philip Mallozzi , Robert David Darrow , Harvey Ellis Cline , Renee Ann Guhde
IPC分类号： A61B5/05
CPC分类号： A61B5/055 , A61B5/0402 , A61B5/042 , A61B5/06 , A61B5/743 , A61B6/503 , A61B6/504 , A61B8/0891 , A61B34/20 , A61B2034/2051 , A61B2090/364 , A61B2090/374 , G01R33/287
摘要： An imaging and interventional system and methods are provided. The system comprises an imaging device for acquiring volumetric image data for an anatomical region of interest, a catheter for acquiring electrophysiological (EP) measurements of the anatomical region of interest, the catheter having at least one tracking coil for detecting signals indicative of a position of the catheter, and, a processor coupled to the catheter for receiving the EP measurements and signals indicative of the position of the catheter. The position of the catheter and EP measurements are combined and superimposed on a resultant image. The method comprises acquiring volumetric image data for an anatomical region of interest, acquiring position data for a catheter inserted in the region of interest, obtaining electrophysiological (EP) measurements for the region of interest and combining the image data, position data and EP measurements into a resultant image for use in the interventional procedure.
摘要翻译： 提供了成像和介入系统和方法。 该系统包括用于获取感兴趣解剖区域的体积图像数据的成像装置，用于获取感兴趣解剖区域的电生理学（EP）测量值的导管，所述导管具有至少一个跟踪线圈，用于检测指示位置的信号 导管，以及耦合到导管的处理器，用于接收EP测量值和指示导管位置的信号。 将导管的位置和EP测量结合并叠加在合成的图像上。 该方法包括获取感兴趣的解剖区域的体积图像数据，获取插入在感兴趣区域中的导管的位置数据，获得感兴趣区域的电生理（EP）测量值，并将图像数据，位置数据和EP测量结合到 用于介入程序的结果图像。
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公开(公告)号：US06175757B1
公开(公告)日：2001-01-16
申请号：US09017573
申请日：1998-02-02
IPC分类号： A61B812
CPC分类号： A61B8/12 , A61B5/055 , A61B5/06 , A61B5/062 , A61B8/4245 , A61B8/4461 , Y10S128/916
摘要： An invasive probe for mapping the walls of a lumen employs a real-time tracking means and a wall distance measurement means. As the probe is advanced within the lumen, the real-time tracking means provides three-dimensional coordinates of the probe's position and orientation. Concurrent with probe localization, the distance between the probe and the lumen walls is measured. Both the probe position and the wall distance measurement are sent to a data acquisition system which in turn provides a graphic or numeric display to the operator. Probe tracking can be performed with radio-frequency, magnetic resonance, ultrasonic techniques or the like. If desired, lumen wall distance measurements can be performed with magnetic resonance or ultrasound methods. Lumen wall distance measurements can also be performed with mechanical devices such as balloons and/or expanding structures.
摘要翻译： 用于映射管腔壁的入侵探针采用实时跟踪装置和壁距测量装置。 当探头在管腔内前进时，实时跟踪装置提供探头位置和方位的三维坐标。 与探头定位同时测量探头与腔壁之间的距离。 探头位置和墙壁距离测量都发送到数据采集系统，该系统又向操作员提供图形或数字显示。 可以使用射频，磁共振，超声波技术等进行探测跟踪。 如果需要，可以用磁共振或超声波方法进行管腔壁距离测量。 腔壁距离测量也可以用诸如球囊和/或膨胀结构的机械装置进行。
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公开(公告)号：US06571020B1
公开(公告)日：2003-05-27
申请号：US09603536
申请日：1999-11-12
IPC分类号： G06K940
CPC分类号： G01S7/52034
摘要： Secondary data set information is incorporated into a primary data set (such as a digital image) retaining a desired dynamic range and retaining the original primary set data quality. The secondary data set information is ‘smuggled’ into the least significant bits of the primary data set to result in an enhanced data set. If desired, the primary data word can be shifted toward the most significant bit. The enhanced data set may be viewed as if it were the original primary data set with existing playback devices, however it now includes additional ‘smuggled’ information which may be played back in coordination with the primary data set information. One example is flow-direction information ‘smuggled’ into an angiographic image. The least significant bits of the enhanced data words may be used to select the color map and color code the images. A user-adjustable intensity threshold can also be employed to select between color maps. Information stored in this fashion results in a substantial savings in disk storage requirements. Also, since the information of the primary and secondary data sets are merged into a single word, they will remain together throughout many different types of processing, such as maximum intensity projection in volumetric imaging.
摘要翻译： 次要数据集信息被并入保留所需动态范围并保留原始主要数据质量的主数据集（例如数字图像）中。 辅助数据集信息被“走私”到主数据集的最低有效位以产生增强的数据集，如果需要，可以将主数据字移向最高有效位，增强数据集可以被看到 好像它是现有播放设备的原始主要数据集，但是它现在包括可以与主数据集信息配合播放的其他“走私”信息。 一个例子是“走私”到血管造影图像中的流向信息，增强数据字的最低有效位可以用于选择彩色图和彩色图像，还可以使用用户可调节的强度阈值来选择 以这种方式存储的信息可以大大节省磁盘存储要求，而且由于主数据集和辅助数据集的信息被合并成一个单词，它们将保持在许多不同类型的处理中，例如 作为体积成像中的最大强度投影。
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公开(公告)号：US6129667A
公开(公告)日：2000-10-10
申请号：US017565
申请日：1998-02-02
CPC分类号： A61B5/06 , A61B1/00183 , A61B5/0084 , A61B5/02007 , A61B8/0841 , A61B5/0075 , A61B5/055
摘要： An invasive probe for determining the morphological characteristics of walls of a lumen employs a real-time tracking means and an optical spectral measurement means. As the probe is advanced within the lumen, the real-time tracking means provides three-dimensional coordinates of the probe's position and orientation. Concurrent with probe localization, measurement of the spectral properties of the lumen wall are made by detecting the reflectance and/or absorption of light at the lumen wall. Both the probe position and the spectral measurement are sent to a data acquisition system which in turn provides an graphic or numeric display to the operator. Probe tracking can be performed with radio-frequency, magnetic resonance, ultrasonic techniques or the like. If desired, spectral measurements can be made in the visible, ultra-violet or infra-red spectral bands to provide optimized detection of chemical species of interest.
摘要翻译： 用于确定管腔壁的形态特征的入侵探针采用实时跟踪装置和光谱测量装置。 当探头在管腔内前进时，实时跟踪装置提供探头位置和方位的三维坐标。 与探针定位同时，通过检测管腔壁上的光的反射和/或吸收来测量管腔壁的光谱特性。 探头位置和光谱测量都被发送到数据采集系统，数据采集系统又向操作者提供图形或数字显示。 可以使用射频，磁共振，超声波技术等进行探测跟踪。 如果需要，可以在可见光，紫外线或红外光谱带中进行光谱测量，以提供感兴趣的化学物质的优化检测。
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10.发明授权
公开(公告)号：US5694142A
公开(公告)日：1997-12-02
申请号：US340783
申请日：1994-11-17
IPC分类号： A61B17/00 , A61B6/03 , A61B19/00 , G06F3/00 , G06F3/01 , G06F19/00 , G06T1/00 , G06T17/40 , G09G5/00
CPC分类号： G06F3/013 , A61B90/36 , G06F19/321 , G06F19/3437 , G06F19/3481 , A61B2090/365 , A61B2090/371 , A61B2090/372 , A61B2090/502 , G06F19/3406
摘要： An interactive three-dimensional (3D) pointing device for selecting points within a subject employs a tracking device which determines the position of the operator, a semi-transparent screen positioned by the operator and the subject and provides this information to a model workstation. The model workstation superimposes computer graphic images of internal structures of the subject on a the semi-transparent screen through which the operator is viewing the subject. The superimposed image is derived from image data either previously generated and stored or obtained with an imaging system. The images of the internal structures are registered with the operator's view of the external structures of the operator. The operator interactively views internal and external structures and the relation between them simultaneously, while moving the screen to select 3D target points at an image depth within the subject. Optionally other input devices may be used to identify current `target points` as selected points. The 3D points are then provided to an output device which utilizes them. Another embodiment employs stereoscopic viewing methods to provide 3D representations of the internal images superimposed on external structures to allow the operator to employ parallax to select 3D points.
摘要翻译： 用于选择对象内的点的交互式三维（3D）定点设备使用确定操作者的位置的跟踪设备，由操作员和被摄体定位的半透明屏幕，并将该信息提供给模型工作站。 模型工作站将被摄体的内部结构的计算机图形图像叠加在操作者正在观看主体的半透明屏幕上。 叠加的图像从先前生成并存储或获得成像系统的图像数据导出。 内部结构的图像以操作员对操作者的外部结构的视图进行记录。 操作者在移动屏幕的同时在内部和外部结构以及它们之间的关系上交互地观察在主体内的图像深度处选择3D目标点。 可选地，可以使用其他输入设备来将当前的“目标点”识别为所选择的点。 然后将3D点提供给利用它们的输出装置。 另一实施例采用立体观看方法来提供叠加在外部结构上的内部图像的3D表示，以允许操作者使用视差来选择3D点。
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