摘要:
This invention relates to compounds that bind to intracellular receptors and/or modulate activity of intracellular receptors, and to methods for making and using such compounds.
摘要:
This document describes a process of producing gel microparticles, which are consistent in size and morphology. Through the process of coacervation, large volumes of gel microparticle slurry can be produced by scaling up reactor vessel size. Particles can be repeatedly dehydrated and rehydrated in accordance to their environment, allowing for the storage of particles in a non-solvent such as ethanol. Gel slurries exhibit a Bingham plastic behavior in which the slurry behaves as a solid at shear stresses that are below a critical value. Upon reaching the critical shear stress, the slurry undergoes a rapid decrease in viscosity and behaves as a liquid. The rheological behavior of these slurries can be adjusted by changing the compaction processes such as centrifugation force to alter the yield-stress. The narrower distribution and reduced size of these particles allows for an increase in FRESH printing fidelity.
摘要:
A method and system for processing a polymer includes providing a molten polymer and processing the polymer into malleable components for delivery to a spirally wound conveying surface. Vibratory forces may be utilized to urge the components along the length of the conveying surface as they undergo crystallizing or drying or crystallizing and drying. Additional supplemental temperature control may be employed to affect crystallization and/or drying of the components along the conveying surface.
摘要:
Masking films comprise a transparent base, preferably a polyester or a polycarbonate, directly carrying a masking film in the form of a dyed transparent plastics material based upon a vinyl chloride-vinyl acetate copolymer coating, which contains an aromatic polyester-based polyurethane. The amount of vinyl acetate and polyurethane in the coating preferably comprises 30% to 65% w/w of its total polymer content.
摘要:
The laser imaging material comprises a laser-transparent support layer of, for example, polyester. A first overlying layer is laser-transparent and formed from a binder that is instantaneously thermally-chemically-decomposable with the production of a gas, for example, an acrylic or methacrylic homopolymer or copolymer, a cellulosic polymer, or a homopolymer or copolymer of stryene. A second overlying layer is formed from such a material, the same as or different from that of the first overlying layer, pigmented with carbon black. Upon laser irradiation through the support layer 10, selected portions of the carbon black are transferred to a suitable receptor surface such as paper or a lithographic plate.
摘要:
A rescue line apparatus is configured as a horizontal tether for being readily connected between a door and a portion of the door jamb or other entry location and extending a line as the user moves within the structure. The device allows the user to readily locate their way back for egressing the structure, and can be readily disengaged by the user, which activates a braking system that prevents unit “run-away”. A multi-attach anchor head couples the far end of the line to any desired structure, and has a beacon assembly which outputs a light pattern of sufficient brightness to be seen by the user when visually locating their attachment point within the structure. A multi-element visual indicator is configured for indicating line extension distance, and displaying tether line status. Many options promote safety and a fully cooperative environment.
摘要:
The present invention provides a bar-code driven, completely automated, microplate-based analyzer system for performing chemical, biochemical or biological assays. The analyzer is a modular, bench-top instrument that compactly integrates subsystems for sample dispensing, liquid handling, microplate transport, thermal incubation, vortexing, solid phase separation and optical reading. An internal processor is included for automating the instrument, and a user interface to facilitate communication with the operator via a touch-sensitive liquid-crystal display (LCD), and communicating with a remote network via multiple protocols. The analyzer includes firmware resident within the processing system and the user interface allows the operator to select pre-defined assay batch protocols and the user interface is configured in such as way so as to restrict an operator from programming the firmware.
摘要:
A broadband computer system comprising a network, a client computer comprising a secure log-on means, a user interaction means, a display means, processing means and client data storage means, wherein applications used on the client computer are stored on the client data storage means; a server connected to the network comprising a secure log-on verification means and server data storage means, wherein the secure log-on means communicates with the secure log-on verification means across the network to authenticate a user and, after authentication, the processing means of the client computer provides a suite of applications for use by the user and wherein any user data required by the suite of applications is provided across the network by the server data storage means.
摘要:
The present invention provides a bar-code driven, completely automated, microplate-based analyzer system for performing chemical, biochemical or biological assays. The analyzer is a modular, bench-top instrument that compactly integrates subsystems for sample dispensing, liquid handling, microplate transport, thermal incubation, vortexing, solid phase separation and optical reading. An internal processor is included for automating the instrument, and a user interface to facilitate communication with the operator via a touch-sensitive liquid-crystal display (LCD), and communicating with a remote network via multiple protocols. The analyzer includes firmware resident within the processing system and the user interface allows the operator to select pre-defined assay batch protocols and the user interface is configured in such as way so as to restrict an operator from programming the firmware.
摘要:
A process for feeding a slurry of thermoplastic synthetic polymer particles such as polyethylene terephthalate homopolymers and copolymers in combination with a liquid such as water at a liquid temperature greater than the normal boiling point of the liquid, under a pressure greater than the vapor pressure of the liquid at the liquid temperature, into a separation zone such as a centrifugal dryer, and within the separation zone: a. separating the liquid from the particles, and b. drying the particles; while under a high pressure equal to or greater than the vapor pressure of the liquid. There is also provided a process for decoupling the dried particles from the separation zone to an atmosphere having a pressure less than the vapor pressure of the liquid while maintaining the vapor pressure of the particles prior to decoupling equal to or above the vapor pressure of the liquid at the liquid temperature.