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1.1,2,3-Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia 失效
标题翻译: 1,2,3-三取代的芳基和杂芳基衍生物作为代谢调节剂以及与之相关疾病的预防和治疗,如糖尿病和高血糖公开(公告)号:US20060217379A1
公开(公告)日:2006-09-28
申请号:US10541657
申请日:2004-01-14
申请人: Robert Jones , Graeme Semple , Beatriz Fioravanti , Guilherme Pereira , Imelda Calderon , Jane Uv , Kameshwari Duvvuri , Jin Choi , Yifeng Xiong , Vibha Dave , Mihai Azimioara
发明人: Robert Jones , Graeme Semple , Beatriz Fioravanti , Guilherme Pereira , Imelda Calderon , Jane Uv , Kameshwari Duvvuri , Jin Choi , Yifeng Xiong , Vibha Dave , Mihai Azimioara
IPC分类号: A61K31/5377 , A61K31/506 , A61K31/454 , C07D413/14 , C07D403/14
CPC分类号: C07D213/68 , C07D213/79 , C07D239/34 , C07D239/50 , C07D295/096 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/14 , C07D411/14 , C07D413/14 , C07D417/14 , C07D419/14
摘要: The present invention relates to certain 1,2,3-trisubstituted aryl and heteroaryl derivatives of Fomula (Ia) that are modulators of metabolism. Accordingly, compounds of the present invention are useful in the prophylaxis or treatment of metabolic disorders and complications thereof, such as, diabetes and obesity.
摘要翻译: 本发明涉及作为代谢调节剂的Fomula(Ia)的某些1,2,3-三取代的芳基和杂芳基衍生物。 因此,本发明的化合物可用于预防或治疗代谢紊乱及其并发症,例如糖尿病和肥胖症。