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公开(公告)号：US20170101272A1
公开(公告)日：2017-04-13
申请号：US15276148
申请日：2016-09-26
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Claudio Cherubini , Andreas Drechsler , Reto Huesser , Nenad Milicevic , Gottlieb Schacher
CPC classification number: B65G33/04 , B65G33/06 , B65G2201/0261 , G01N35/04 , G01N2035/0406 , G01N2035/0465 , G01N2035/0487
Abstract: A conveyor device for conveying test tube holders in a laboratory distribution system is presented. The conveyor device is a screw conveyor device comprising a helical track having a helix axis and a drive shaft having an axis of rotation parallel or coaxial to the helix axis, which drive shaft is adapted to be driven to rotate about the axis of rotation for causing a movement of one test tube holder or a plurality of test tube holders contacting the helical track between an entry region and an exit region. The entry region and the exit region are spaced in a direction of the helix axis. A laboratory distribution system for conveying test tube holders and a laboratory automation system comprising a laboratory distribution system are also presented.
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公开(公告)号：US10436685B2
公开(公告)日：2019-10-08
申请号：US15417858
申请日：2017-01-27
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Claudio Cherubini , Martin Kopp , Nenad Milicevic , Daniel Mueller , Emad Sarofim , Goran Savatic
IPC: G01N1/40 , G01N15/04 , G01N35/00 , G01N35/10 , B01L3/00 , B04B11/04 , B04B13/00 , B04B5/04 , B04B7/08 , C12M1/00
Abstract: A method for processing particles contained in a liquid biological sample is presented. The method uses a rotatable vessel for processing particles contained in a liquid biological sample. The rotatable vessel has a longitudinal axis about which the vessel is rotatable, an upper portion having a top opening for receiving the liquid comprising the particles, a lower portion for holding the liquid while the rotatable vessel is resting, the lower portion having a bottom, and an intermediate portion located between the upper portion and the lower portion, the intermediate portion having a lateral collection chamber for holding the liquid while the rotatable vessel is rotating. The method employs dedicated acceleration and deceleration profiles for sedimentation and re-suspension of the particles of interest.
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公开(公告)号：US20180010990A1
公开(公告)日：2018-01-11
申请号：US15417858
申请日：2017-01-27
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Claudio Cherubini , Martin Kopp , Nenad Milicevic , Daniel Mueller , Emad Sarofim , Goran Savatic
IPC: G01N1/40 , B04B5/04 , B04B7/08 , B01L3/00 , G01N35/10 , G01N35/00 , G01N15/04 , B04B13/00 , B04B11/04
CPC classification number: G01N1/4077 , B01L3/5021 , B01L2300/0848 , B01L2300/0858 , B01L2300/168 , B01L2400/086 , B04B5/0407 , B04B7/08 , B04B11/04 , B04B13/00 , C12M47/02 , G01N1/405 , G01N15/042 , G01N35/00584 , G01N35/10 , G01N2001/4083 , G01N2015/045 , Y10T436/111666 , Y10T436/25375
Abstract: A method for processing particles contained in a liquid biological sample is presented. The method uses a rotatable vessel for processing particles contained in a liquid biological sample. The rotatable vessel has a longitudinal axis about which the vessel is rotatable, an upper portion comprising a top opening for receiving the liquid comprising the particles, a lower portion for holding the liquid while the rotatable vessel is resting, the lower portion comprising a bottom, and an intermediate portion located between the upper portion and the lower portion, the intermediate portion comprising a lateral collection chamber for holding the liquid while the rotatable vessel is rotating. The method employs dedicated acceleration and deceleration profiles for sedimentation and re-suspension of the particles of interest.
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公开(公告)号：US20240198347A1
公开(公告)日：2024-06-20
申请号：US18532264
申请日：2023-12-07
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Daniel Mueller , Claudio Cherubini , Dirk Abeln , Reto Huesser , Marko Simic , Nenad Milicevic , Michael Zeder
CPC classification number: B01L9/50 , B01L9/06 , G01N35/00584 , B01L2200/025 , B01L2200/0689 , B01L2300/041 , B01L2300/12
Abstract: The present invention relates to an instrument for automatically removing sealing covers from sample vessels (and/or for automatically sealing or resealing sample vessels with sealing covers, the instrument comprising a vessel holder for holding a sample vessel, and a suction/induction device comprising a suction member for holding a sealing cover, and an induction member comprising at least one induction coil, with the suction/induction device and the vessel holder being arranged in an axially movable manner with regard to each other, and, in use, the at least one induction coil is arranged above a bottom of the suction member. In addition, the present invention relates to a laboratory automation system comprising such instrument as well as a plurality of pre-analytical, analytical and/or post-analytical stations, and also relates to a method of automatically removing sealing covers from sample vessels and a method of automatically sealing or resealing sample vessels with sealing covers.
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公开(公告)号：US09957111B2
公开(公告)日：2018-05-01
申请号：US15276148
申请日：2016-09-26
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Claudio Cherubini , Andreas Drechsler , Reto Huesser , Nenad Milicevic , Gottlieb Schacher
CPC classification number: B65G33/04 , B65G33/06 , B65G2201/0261 , G01N35/04 , G01N2035/0406 , G01N2035/0465 , G01N2035/0487
Abstract: A conveyor device for conveying test tube holders in a laboratory distribution system is presented. The conveyor device is a screw conveyor device comprising a helical track having a helix axis and a drive shaft having an axis of rotation parallel or coaxial to the helix axis, which drive shaft is adapted to be driven to rotate about the axis of rotation for causing a movement of one test tube holder or a plurality of test tube holders contacting the helical track between an entry region and an exit region. The entry region and the exit region are spaced in a direction of the helix axis. A laboratory distribution system for conveying test tube holders and a laboratory automation system comprising a laboratory distribution system are also presented.
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公开(公告)号：US20200033240A1
公开(公告)日：2020-01-30
申请号：US16542786
申请日：2019-08-16
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Claudio Cherubini , Martin Kopp , Nenad Milicevic , Daniel Mueller , Emad Sarofim , Goran Savatic
IPC: G01N1/40 , B01L3/00 , C12M1/00 , B04B5/04 , B04B7/08 , B04B11/04 , B04B13/00 , G01N15/04 , G01N35/00 , G01N35/10
Abstract: A method and system for processing particles contained in a liquid biological sample is presented. The method uses a rotatable vessel for processing particles contained in a liquid biological sample. The rotatable vessel has a longitudinal axis about which the vessel is rotatable, an upper portion having a top opening for receiving the liquid comprising the particles, a lower portion for holding the liquid while the rotatable vessel is resting, the lower portion having a bottom, and an intermediate portion located between the upper portion and the lower portion, the intermediate portion having a lateral collection chamber for holding the liquid while the rotatable vessel is rotating. The method employs dedicated acceleration and deceleration profiles for sedimentation and re-suspension of the particles of interest.
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公开(公告)号：US11169061B2
公开(公告)日：2021-11-09
申请号：US16542786
申请日：2019-08-16
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Claudio Cherubini , Martin Kopp , Nenad Milicevic , Daniel Mueller , Emad Sarofim , Goran Savatic
IPC: G01N1/40 , G01N15/04 , G01N35/00 , G01N35/10 , B01L3/00 , C12M1/00 , B04B5/04 , B04B7/08 , B04B11/04 , B04B13/00
Abstract: A method and system for processing particles contained in a liquid biological sample is presented. The method uses a rotatable vessel for processing particles contained in a liquid biological sample. The rotatable vessel has a longitudinal axis about which the vessel is rotatable, an upper portion having a top opening for receiving the liquid containing the particles, a lower portion for holding the liquid while the rotatable vessel is resting, the lower portion having a bottom, and an intermediate portion located between the upper portion and the lower portion, the intermediate portion having a lateral collection chamber for holding the liquid while the rotatable vessel is rotating. The method employs dedicated acceleration and deceleration profiles for sedimentation and re-suspension of the particles of interest.
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公开(公告)号：US11112419B2
公开(公告)日：2021-09-07
申请号：US16031446
申请日：2018-07-10
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Hans van Mierlo , Gottlieb Schacher , Marcel Kaeppeli , Reto Huesser , Andreas Drechsler , Matthias Goetz , Nenad Milicevic
IPC: G01N35/02 , B65G17/00 , B65G17/12 , B65G17/46 , B65G47/57 , B65G17/32 , B65G17/34 , B65G43/00 , G01N35/04
Abstract: A laboratory distribution system is presented. The system comprises diagnostic laboratory container carriers and a conveyor. The conveyor comprises an endless drive defining a closed-loop conveyor pathway. The system comprises supporting elements attached to the endless drive. The supporting elements receive a container carrier and transport the container carrier in an upright position along a pathway section. The supporting elements are mounted pivotally about a horizontal pivot axis to the drive and structured such that a center of gravity of the supporting element with or without an empty or loaded container carrier is arranged below and vertically aligned with the pivot axis when the supporting element is in an upright position such that each supporting element is free to pivot about the associated pivot axis under the effect of gravitational forces acting on the supporting element for maintaining the supporting elements in an upright position while travelling along the path.
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公开(公告)号：US20190004077A1
公开(公告)日：2019-01-03
申请号：US16031446
申请日：2018-07-10
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Hans van Mierlo , Gottlieb Schacher , Marcel Kaeppeli , Reto Huesser , Andreas Dreschler , Matthias Goetz , Nenad Milicevic
Abstract: A laboratory distribution system is presented. The system comprises diagnostic laboratory container carriers and a conveyor. The conveyor comprises an endless drive defining a closed-loop conveyor pathway. The system comprises supporting elements attached to the endless drive. The supporting elements receive a container carrier and transport the container carrier in an upright position along a pathway section. The supporting elements are mounted pivotally about a horizontal pivot axis to the drive and structured such that a center of gravity of the supporting element with or without an empty or loaded container carrier is arranged below and vertically aligned with the pivot axis when the supporting element is in an upright position such that each supporting element is free to pivot about the associated pivot axis under the effect of gravitational forces acting on the supporting element for maintaining the supporting elements in an upright position while travelling along the path.
