Drug delivery system for hydrophobic drugs
    4.
    发明申请
    Drug delivery system for hydrophobic drugs 审中-公开
    疏水药物的药物输送系统

    公开(公告)号:US20060039965A1

    公开(公告)日:2006-02-23

    申请号:US11254400

    申请日:2005-10-20

    摘要: Compositions comprising microaggregates containing hydrophobic drugs, as well as methods for their production, are described. Such microaggregates may include micelle structures or combinations thereof with liposomes, and constitute an effective delivery vehicle for a hydrophobic agent. Methods for microaggregate production include the use of preferred lipid compounds and processing conditions favo the production of small aggregates for improved filter sterilization.

    摘要翻译: 描述了包含含有疏水性药物的微团聚体的组合物及其生产方法。 这种微团聚体可以包括胶束结构或其与脂质体的组合,并且构成疏水剂的有效递送载体。 微团聚体生产的方法包括使用优选的脂质化合物和加工条件,以生产小聚集体以改进过滤器灭菌。