公开(公告)号：US06858234B2

公开(公告)日：2005-02-22

申请号：US10349714

申请日：2003-01-23

申请人： Ryuji Murayama ,  Takeo Kanafuji ,  Yasuhito Muranaka ,  Rumiko Muranaka ,  Kazuo Sato ,  Akira Sekigawa ,  Kazuhiko Yamada ,  Yoshio Suzuki ,  Hiroyuki Ikemoto

发明人： Ryuji Murayama ,  Takeo Kanafuji ,  Yasuhito Muranaka ,  Rumiko Muranaka ,  Kazuo Sato ,  Akira Sekigawa ,  Kazuhiko Yamada ,  Yoshio Suzuki ,  Hiroyuki Ikemoto

IPC分类号： A23J1/12 ,  A61K36/899 ,  A61K38/00 ,  A61K38/55 ,  C07K14/415 ,  C12N9/26 ,  C12N9/99 ,  A61K35/78

CPC分类号： A61K36/899

摘要： The process for the preparation of amylase inhibitor including the steps of: (A) obtaining an extract solution containing the amylase inhibitor; (B) insolubilizing the amylase inhibitor by salting out by addition of a salt or salts to the solution obtained in the step (A) and recovering the insolubilized substance resulting from the salting out; and (C) directly drying the insolubilized substance recovered in the step (B) or dissolving the insolubilized substance in water to prepare an aqueous solution, and desalting and drying the aqueous solution to recover the amylase inhibitor, whereby, an amylase inhibitor in high concentrations 0.19 AI is prepared that shows highly inhibitive activity against the amylase in high yield and with good productivity.

摘要翻译： 制备淀粉酶抑制剂的方法，包括以下步骤：（A）获得含有淀粉酶抑制剂的提取液; （B）通过向步骤（A）中得到的溶液中加入盐或盐盐析而使淀粉酶抑制剂不溶解并回收由盐析产生的不溶物质; 和（C）直接干燥步骤（B）中回收的不溶物质或将不溶物质溶解在水中以制备水溶液，并对该水溶液进行脱盐干燥以回收淀粉酶抑制剂，从而得到高浓度的淀粉酶抑制剂 制备了以高产率和高生产率对淀粉酶具有高度抑制活性的AII。

公开(公告)号：US06583692B2

公开(公告)日：2003-06-24

申请号：US09850695

申请日：2001-05-08

申请人： Stephen C. Holme ,  Hiroyuki Ikemoto

发明人： Stephen C. Holme ,  Hiroyuki Ikemoto

IPC分类号： H01P1208

CPC分类号： H01P1/208

摘要： A filter that produces a multiple passband response as a single device. The multiple passband filter has a plurality of poles concentrated in a desired passband of the filter. A plurality of zeroes are located outside of the desired passband to form passband edges. One or more zeroes are located in a central portion of the passband to form multiple passbands within the passband edges.

公开(公告)号：US4973080A

公开(公告)日：1990-11-27

申请号：US444761

申请日：1989-12-01

申请人： Hiroyuki Ikemoto ,  Shuuichi Buma ,  Kaoru Ohashi ,  Toshio Aburaya ,  Takashi Yonekawa ,  Toshio Oonuma ,  Kunihito Sato ,  Masaki Kawanishi ,  Toshiaki Hamada ,  Kouichi Kokubo ,  Shinichi Tagawa

发明人： Hiroyuki Ikemoto ,  Shuuichi Buma ,  Kaoru Ohashi ,  Toshio Aburaya ,  Takashi Yonekawa ,  Toshio Oonuma ,  Kunihito Sato ,  Masaki Kawanishi ,  Toshiaki Hamada ,  Kouichi Kokubo ,  Shinichi Tagawa

IPC分类号： B60G17/017

CPC分类号： B60G17/017 ,  B60G2202/15 ,  B60G2204/80 ,  B60G2400/104 ,  B60G2400/106 ,  B60G2400/204 ,  B60G2400/252 ,  B60G2400/30 ,  B60G2400/38 ,  B60G2400/41 ,  B60G2400/50 ,  B60G2400/51 ,  B60G2400/73 ,  B60G2400/90 ,  B60G2500/30 ,  B60G2600/02 ,  B60G2600/04 ,  B60G2600/08 ,  B60G2600/20 ,  B60G2600/26 ,  B60G2600/60 ,  B60G2600/70 ,  B60G2600/85 ,  B60G2800/012 ,  B60G2800/014

摘要： In a hydraulic suspension system, a plurality of actuators having working fluid chambers are provided. Each actuator is adapted to increase and decrease vehicle height as the results of the supply and the discharge of working fluid to and from its working fluid chamber, respectively. Working fluid supply passages supply working fluid at supply pressure to the working fluid chambers and working fluid discharge passages discharge working fluid from the working fluid chambers. Cut-off valves and pressure control devices are provided in the supply passages and the discharge passages. Each cut-off valve is adapted to remain in its closed position whenever the supply pressure is not more than a predetermined value. Each pressure control device is adapted to control the supply of the working fluid to and the discharge from the associated working fluid chamber to adjust the pressure within the chamber. The system further comprises devices for detecting the pressures within the working fluid chambers and a device for determining the supply pressure. The pressure control devices are controlled so that their controlling pressures may substantially be equal to the pressures within the associated working fluid chambers determined by the pressure determining devices at least until the cut-off valves are opened.

公开(公告)号：US4958850A

公开(公告)日：1990-09-25

申请号：US316918

申请日：1989-02-28

申请人： Shuuichi Buma ,  Hiroyuki Ikemoto

发明人： Shuuichi Buma ,  Hiroyuki Ikemoto

IPC分类号： B60G17/04

CPC分类号： B60G17/04

摘要： A hydraulic circuit system for a vehicle height control device is provided comprising actuators for increasing and decreasing vehicle heights as respective results of the supply and the discharge of working fluid to and from their working fluid chambers, a supply passage means and a discharge passage means for supplying and discharging working fluid to and from the chambers, respectively, control valve means for controlling the supply and the discharge of working fluid, cut-off valve means provided in the supply and discharge passage means and adapted to remain in their closed position so long as the pressure within the supply passage means is not more than a predetermined value. The system further comprises a bypass valve means for selectively communicating the supply and the discharge passage means with each other so that the pressure within the supply passage means may be controlled. The opening and closing of the cut-off valve means can be performed by solely controlling the bypass valve means, thereby reducing the electric power required to operate the system. Undesired decrease in vehicle height can positively be prevented by the cut-off valve means even in the event where the control valve means is shifted for supplying the working fluid to the chambers under the condition where the pressure within the supply passage means is relatively low.

公开(公告)号：US4797823A

公开(公告)日：1989-01-10

申请号：US921138

申请日：1986-10-21

申请人： Hiroyuki Ikemoto ,  Nobutaka Oowa ,  Yasutaka Hayashi ,  Shunichi Doi

发明人： Hiroyuki Ikemoto ,  Nobutaka Oowa ,  Yasutaka Hayashi ,  Shunichi Doi

IPC分类号： B60G17/016 ,  B60G17/00

CPC分类号： B60G17/0162

摘要： In this roll control system, suspension means are provided for resiliently suspending the vehicle wheels with variable hardness/softness characteristics, each suspension means including an actuator with a pressure chamber which increases or decreases wheel suspension height according to the supply or discharge of working fluid. Working fluid supply/discharge means are provided for the actuators, to supply and discharge working fluid to and from actuator pressure chambers. The road speed, the steering angle, and the actual body roll angle are detected. Means for computing and control computes a steady state vehicle body roll angle .phi..sub..infin. from the vehicle speed and steering angle, advances the phase of a signal indicative of .phi..sub..infin. to compute a compensating roll angle value .PHI..sub..infin., and then computes a difference value .phi. based upon a desired roll angle .phi..sub.a, .PHI..sub..infin., and the actual roll angle .phi..sub.t, according to the equation:.phi.=.phi..sub.a -(k1.PHI..infin.+k2.phi.t)where k1 and k2 are positive constants. The computing and control means is adapted to control the working fluid supplying and discharging means based upon .phi. when the absolute value of .phi. is larger than a predetermined value .phi..sub.1, and to control the hardness/softness characteristics of the suspension means according to the absolute value of .phi. when the absolute value of .phi. is smaller than .phi..sub.1.

摘要翻译： 在该辊控制系统中，提供悬挂装置用于弹性地悬挂具有可变硬度/柔软度特性的车轮，每个悬架装置包括具有压力室的致动器，该压力室根据工作流体的供给或排放而增加或减少车轮悬挂高度。 为致动器提供工作流体供应/排放装置，以将工作流体供给和排出到致动器压力室。 检测道路速度，转向角度和实际车身倾斜角度。 用于计算和控制的装置根据车辆速度和转向角度计算稳态车体侧倾角度phi INFINITY，使表示phi INFINITY的信号的相位前进，以计算补偿侧倾角度值PHI INFINITY，然后计算差值phi 基于期望的滚动角度phi，PHI INFINITY和实际滚动角度，根据以下等式：其中k1和k2是正常数的公式：phi = phi a-（k1 PHI INFINITY + k2 phi t） 计算和控制装置适用于当phi的绝对值大于预定值phi 1时基于phi控制工作流体供给和排出装置，并且根据绝对值控制悬挂装置的硬度/柔软度特性 当phi的绝对值小于phi 1时，phi的值。

公开(公告)号：US5119297A

公开(公告)日：1992-06-02

申请号：US484891

申请日：1990-02-26

申请人： Shuuichi Buma ,  Hiroyuki Ikemoto ,  Toshio Aburaya ,  Takashi Yonekawa ,  Kunihito Sato ,  Toshio Onuma ,  Kaoru Ohashi

发明人： Shuuichi Buma ,  Hiroyuki Ikemoto ,  Toshio Aburaya ,  Takashi Yonekawa ,  Kunihito Sato ,  Toshio Onuma ,  Kaoru Ohashi

IPC分类号： B60G17/015 ,  B60G17/016

CPC分类号： B60G17/016 ,  B60G2400/104 ,  B60G2400/106 ,  B60G2400/204 ,  B60G2400/252 ,  B60G2400/30 ,  B60G2400/304 ,  B60G2400/33 ,  B60G2400/38 ,  B60G2400/41 ,  B60G2400/50 ,  B60G2400/70 ,  B60G2400/952 ,  B60G2500/30 ,  B60G2600/02 ,  B60G2600/04 ,  B60G2600/26 ,  B60G2600/604 ,  B60G2600/72 ,  B60G2800/012 ,  B60G2800/014 ,  B60G2800/22

摘要： In a hydraulic active suspension system, a plurality of actuators having working fluid chambers are provided corresponding to vehicle wheels. Each actuator is adapted to increase or decrease vehicle height in response to the hydraulic pressure within its working fluid chamber. The hydraulic pressures within the working fluid chambers are controlled to their desired pressure by associated pressure control devices. A desired pressure computing device is further provided. The computing device calculates the actual values of roll, pitch, heave and warp of a vehicle body from the vehicle heights detected by detecting devices and calculates the differences between the actual values and the associated values of roll, pitch, heave and warp determined by a desired attitude of the vehicle body to compute the desired pressures for the actuators. The degrees of the roll and/or pitch differences are set to be higher than that of the warp difference in contributing to the determination of the desired pressures.

公开(公告)号：US5103397A

公开(公告)日：1992-04-07

申请号：US505472

申请日：1990-04-06

申请人： Hiroyuki Ikemoto ,  Shuuichi Buma ,  Toshio Aburaya ,  Takashi Yonekawa ,  Toshio Onuma ,  Tsukasa Watanabe ,  Toshiaki Hamada

发明人： Hiroyuki Ikemoto ,  Shuuichi Buma ,  Toshio Aburaya ,  Takashi Yonekawa ,  Toshio Onuma ,  Tsukasa Watanabe ,  Toshiaki Hamada

IPC分类号： B60G17/015 ,  B60G17/016 ,  B60G17/0185

CPC分类号： B60G17/016 ,  B60G17/0185 ,  B60G2400/104 ,  B60G2400/106 ,  B60G2400/204 ,  B60G2400/30 ,  B60G2400/38 ,  B60G2400/41 ,  B60G2400/50 ,  B60G2400/73 ,  B60G2600/02 ,  B60G2600/08 ,  B60G2600/20 ,  B60G2800/012 ,  B60G2800/702 ,  B60G2800/704 ,  B60G2800/80

摘要： In a hydraulic active suspension system, a plurality of actuators having working fluid chambers are provided corresponding to vehicle wheels. Each actuator is adapted to increase and decrease vehicle height in response to the pressure within its working chamber, which is controlled by a pressure control device. Vehicle speed and lateral acceleration are detected by corresponding sensors. A control device is further provided for controlling the pressure control device by compensating values determined base upon the lateral acceleration detected. The control device is adapted to reduce the compensating values in magnitude when the vehicle speed is lower than a predetermined value under which the lateral acceleration sensor sometimes detects a false lateral acceleration, thereby reducing the possibility that the vehicle body may generate an unpleasant roll due to the erroneous control on the pressures within the working fluid chambers based upon a false lateral acceleration.

公开(公告)号：US4807128A

公开(公告)日：1989-02-21

申请号：US16944

申请日：1987-02-20

申请人： Hiroyuki Ikemoto ,  Nobutaka Owa ,  Yasutaka Hayashi ,  Shunichi Doi

发明人： Hiroyuki Ikemoto ,  Nobutaka Owa ,  Yasutaka Hayashi ,  Shunichi Doi

IPC分类号： B60G17/00 ,  B60G17/015 ,  B60G17/016 ,  B60G11/26

CPC分类号： B60G17/0162 ,  B60G2202/42 ,  B60G2204/80 ,  B60G2400/104 ,  B60G2400/106 ,  B60G2400/204 ,  B60G2400/33 ,  B60G2400/41 ,  B60G2500/102 ,  B60G2500/22 ,  B60G2500/30 ,  B60G2600/02 ,  B60G2600/04 ,  B60G2600/14 ,  B60G2600/26 ,  B60G2600/70 ,  B60G2600/82 ,  B60G2800/012 ,  B60G2800/24

摘要： In this system for vehicle roll control, one actuator assembly is provided corresponding to each vehicle wheel and resiliently suspends it from the vehicle body. Each of these actuator assemblies is adapted to increase or decrease the vehicle height at its vehicle wheel as a result of a control signal being supplied. Control means are provided corresponding to the actuator assemblies and serve to supply control signals to them. A vehicle speed detecting means senses road speed, a steering angle detecting means senses steering angle, a means senses the rate of change of steering angle, and a means detects the actual roll angle .phi..sub.t of the vehicle body. A computing and control means computes a steady state roll angle .phi..sub..infin. of the vehicle body from the vehicle speed and the steering angle, advances the phase of a signal representative of the steady state roll angle .phi..sub..infin. to thereby compute a compensating value .PHI..sub..infin. of roll angle, computes an amendment value .phi..sub.x of roll angle in accordance with the rate of change of steering angle, computes the difference .phi. based upon the desired roll angle .phi..sub.a of the vehicle body, the compensating value .PHI..sub..infin., the amendment value .phi..sub.x, and the actual roll angle .phi..sub.t following the equation: .phi.=.phi.a- (k.sub.1 .PHI..sub..infin. +k.sub.2 .PHI.t+k.sub.3 .PHI.x), where k1, k2 and k3 are positive constants; and controls the actuator assemblies, via the control means, in accordance with the difference .phi., when the absolute value of the difference .phi. is larger than a predetermined value.

摘要翻译： 在该车辆侧倾控制系统中，对应于每个车轮提供一个致动器组件，并将其从车身弹性地悬挂。 这些致动器组件中的每一个适于由于提供控制信号而增加或减少其车轮上的车辆高度。 对应于致动器组件提供控制装置并且用于向它们提供控制信号。 车速检测装置感测道路速度，转向角检测装置感测转向角，手段感测转向角的变化率，并且装置检测车身的实际侧倾角。 计算和控制装置根据车速和转向角计算车身的稳态滚动角度phi INFINITY，使代表稳态滚动角度phi INFINITY的信号的相位前进，从而计算出补偿值PHI INFINITY 根据转向角的变化率来计算侧倾角度的修正值φi，根据车身的期望的倾斜角度phi a，补偿值PHI INFINITY，修正值phi x，和实际滚动角度phi，遵循以下等式：phi = phi a-（k1 PHI INFINITY + k2 PHI t + k3 PHI x），其中k1，k2和k3是正常数; 并且当差值phi的绝对值大于预定值时，经由控制装置根据差分phi来控制致动器组件。

公开(公告)号：US4803627A

公开(公告)日：1989-02-07

申请号：US17592

申请日：1987-02-24

申请人： Osamu Yasuike ,  Yasuji Arai ,  Hiroyuki Ikemoto ,  Nobutaka Owa ,  Shunichi Doi

发明人： Osamu Yasuike ,  Yasuji Arai ,  Hiroyuki Ikemoto ,  Nobutaka Owa ,  Shunichi Doi

IPC分类号： B60G17/00 ,  B60G17/015 ,  B60G17/016 ,  B60G21/06

CPC分类号： B60G17/0162

摘要： In this system for vehicle roll control, a plurality of actuator assemblies are provided, one corresponding to each one of the vehicle wheels and resiliently suspending it from the vehicle body. Each of these actuator assemblies is adapted to increase or decrease the vehicle height at a location corresponding to its corresponding vehicle wheel as results of control signals being supplied to it. A plurality of control means are provided corresponding to the actuator assemblies and serve to supply control signals to them. A vehicle speed detecting means senses the road speed of the vehicle, a steering angle detecting means senses the steering angle of the vehicle, and a lateral acceleration detecting means detects the lateral acceleration of the vehicle body. A means for computing and control predictingly computes the roll angle of the vehicle body from the vehicle speed sensed by the vehicle speed detecting means and the steering angle sensed by the steering angle detecting means, and controls the plurality of actuator assemblies, via the plurality of control means, in accordance with the computed roll angle, so as to reduce the rolling of the vehicle body to keep the vehicle body rolling within a determinate range. This computing and control means is further adapted to compare the direction of vehicle steering as detected by the steering angle detecting means with the direction of lateral acceleration of the vehicle body as detected by the lateral acceleration detecting means, and does not effect such controlling of the plurality of actuator assemblies, when the direction of vehicle steering is opposite to the direction of lateral acceleration of the vehicle body.

摘要翻译： 在该车辆侧倾控制系统中，设置有多个致动器组件，一个对应于车轮中的每一个并且使其从车体弹性悬挂。 这些致动器组件中的每一个适于在对应于其对应的车轮的位置处增加或减少车辆高度，作为向其提供的控制信号的结果。 对应于致动器组件提供多个控制装置，并用于向它们提供控制信号。 车速检测装置感测车辆的道路速度，转向角检测装置感测车辆的转向角，横向加速度检测装置检测车身的横向加速度。 用于计算和控制的装置根据车速检测装置感测到的车速预测车身的侧倾角和由转向角检测装置检测到的转向角度，并且经由多个致动器组件 控制装置，根据计算出的滚动角度，以便减少车身的滚动，使车体滚动保持在确定的范围内。 该计算和控制装置还适于将由转向角检测装置检测到的车辆转向方向与由横向加速度检测装置检测到的车体横向加速度的方向进行比较，并且不影响 当车辆转向的方向与车身的横向加速度的方向相反时，多个致动器组件。

公开(公告)号：US08119113B2

公开(公告)日：2012-02-21

申请号：US11632933

申请日：2005-08-18

申请人： Hiroyuki Ikemoto ,  Tsuyoshi Minemura

发明人： Hiroyuki Ikemoto ,  Tsuyoshi Minemura

IPC分类号： A61K9/00 ,  A61K31/74

CPC分类号： A61K31/122 ,  A23L33/10 ,  A61K9/10 ,  A61K9/107 ,  A61K9/145 ,  A61K9/146 ,  A61K9/4858 ,  A61K9/4866 ,  A61K47/10 ,  A61K47/26 ,  A61K47/36

摘要： There is provided a coenzyme Q10-containing composition having a high coenzyme Q10 content and excellent stability and bioavailability of coenzyme Q10, without using synthetic emulsifiers such as glycerin fatty acid esters, polyglycerin fatty acid esters, organic acid monoglycerides or sucrose fatty acid esters.The coenzyme Q10-containing liquid composition is obtained by dispersing and emulsifying coenzyme Q10 in an aqueous liquid containing a water-soluble substance consisting of octenylsuccinate starch and dextrin, and glycerin. The liquid composition may be dried to prepare a coenzyme Q10-containing solid composition.

摘要翻译： 提供了不使用合成乳化剂如甘油脂肪酸酯，聚甘油脂肪酸酯，有机酸单甘油酯或蔗糖脂肪酸酯的辅酶Q10含量高且辅酶Q10的稳定性和生物利用度优异的辅酶Q10组合物。 含辅酶Q10的液体组合物通过将辅酶Q10分散在含有由辛烯基琥珀酸淀粉和糊精组成的水溶性物质的水性液体和甘油中而得到。 可以将液体组合物干燥以制备含辅酶Q10的固体组合物。