公开(公告)号：US20220355310A1

公开(公告)日：2022-11-10

申请号：US17840568

申请日：2022-06-14

Applicant: SHIMADZU CORPORATION

Inventor： Masamitsu SHIKATA ,  Ayaka MINAMIMOTO ,  Akira MURAMATSU ,  Masaki KANAI ,  Seiya FUJIWARA ,  Tetsuo OHASHI ,  Hiroyuki JIKUYA

IPC: B03C1/12 ,  C12Q1/6865 ,  B01D15/38

Abstract: A manufacturing method of an operation pipe, which use a gel to perform operations such as separation, extraction, purification, elution, recovery, analysis and the like of target components that are biological components such as nucleic acids. More specifically, a manufacturing method of an operation pipe, with which it is possible to perform operations such as separation, extraction, purification, elution, recovery, analysis and the like of target components in a sealable pipe by operating magnetic particles in the pipe under a magnetic field from outside of the pipe.

公开(公告)号：US20200282407A1

公开(公告)日：2020-09-10

申请号：US16782064

申请日：2020-02-05

Applicant: SHIMADZU CORPORATION

Inventor： Masamitsu SHIKATA ,  Ayaka MINAMIMOTO ,  Akira MURAMATSU ,  Masaki KANAI ,  Seiya FUJIWARA ,  Tetsuo OHASHI ,  Hiroyuki JIKUYA

IPC: B03C1/12 ,  C12Q1/6865 ,  B01D15/38

Abstract: An operation pipe and a device equipped with the operation pipe, which use a gel to perform operations such as separation, extraction, purification, elution, recovery, analysis and the like of target components that are biological components such as nucleic acids. More specifically, an operation pipe and a device, with which it is possible to perform operations such as separation, extraction, purification, elution, recovery, analysis and the like of target components in a sealable pipe by operating magnetic particles in the pipe under a magnetic field from outside of the pipe.

公开(公告)号：US20220002709A1

公开(公告)日：2022-01-06

申请号：US17292941

申请日：2018-11-22

Applicant: SHIMADZU CORPORATION

Inventor： Seiya FUJIWARA ,  Masaki KANAI ,  Hiroyuki JIKUYA ,  Tetsuo OHASHI ,  Masamitsu SHIKATA ,  Ayaka MINAMIMOTO

IPC: C12N15/10 ,  B01J19/08 ,  B03C1/005 ,  B03C1/28

Abstract: A purpose of the present invention is to suppress reduction in recovery rate of a target component due to a gel adhering to an inner wall surface of a treatment liquid layer. After passing magnetic particles through a gel layer, when moving the magnetic particles in the treatment liquid layer adjacent to the gel layer, the magnetic force source is automatically operated in a longitudinal direction of a tubular container so that the magnetic particles do not enter a range of a certain distance from the gel layer through which the magnetic particles have passed.

公开(公告)号：US20200147604A1

公开(公告)日：2020-05-14

申请号：US16680980

申请日：2019-11-12

Applicant: SHIMADZU CORPORATION

Inventor： Nobuhiro HANAFUSA ,  Ayaka MINAMIMOTO

IPC: B01L3/00 ,  B03C1/02 ,  B01D15/42

Abstract: An apparatus for manipulating magnetic particles includes a latch mechanism. The latch mechanism has a pivoting part provided on a door and an engaging part provided on a main body. In the apparatus for manipulating magnetic particles, a first contact portion of a latch engages with the engaging part at a contact point in a state that the door is closed. The contact point is located more outside of the main body than the pivot axis. Accordingly, in a case where an external force is applied to the door in a direction to open the door in a state that the door is closed, a force is applied from the engaging part to the first contact portion, thereby generating a rotational force in a C direction to the pivoting part. As a result, in the state that the door is closed, it is possible to suppress the door from being opened without a manipulation by the user.