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公开(公告)号：US10408952B2
公开(公告)日：2019-09-10
申请号：US15939096
申请日：2018-03-28
发明人： Paolo Crema , Alessandro Freguglia , Piero Fallica
IPC分类号： G01T1/208 , H01L31/0203 , G01T1/202 , G01T1/20 , G01T7/00
摘要： A radiation scintillator detector comprising a substrate on which are arranged a scintillator module and a silicon photomultiplier optically coupled one to the other. The detector includes a package comprising an outer casing enclosing said scintillator module and said photomultiplier, said package comprising inside said outer casing an inner casing comprising resin reflecting photons, in particular infrared and/or visible photons, emitted by said scintillator module upon receiving a ionizing radiation, enclosing said scintillator module and said photomultiplier.
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公开(公告)号：US12059271B2
公开(公告)日：2024-08-13
申请号：US17644703
申请日：2021-12-16
CPC分类号： A61B5/7264 , A61B5/021 , A61B5/02108 , A61B5/0261 , A61B5/168 , A61B5/18 , A61B5/6826 , A61B5/6893 , A61B5/7239 , A61B5/7246 , A61B5/725 , A61B5/7267 , A61B5/7278 , G06N3/08 , A61B5/02416 , A61B5/7242 , A61B2503/22 , G16H10/40
摘要： Blood pressure signals are reconstructed from PhotoPlethysmoGraphy (PPG) signals by: receiving PPG signals including systolic, diastolic and dicrotic phases; and determining first and second derivatives of the PPG signals and: a first set of values indicative of lengths of the signal paths of the PPG signal, the first derivative and the second derivative thereof in the systolic, diastolic and dicrotic phases; a second set of values indicative of relative durations of the PPG signal and the first and second derivatives thereof in the systolic, diastolic and dicrotic phases; and a third set of values indicative of the time separation of peaks and/or valleys in subsequent waveforms of the PPG signal. Reconstruction also includes applying artificial neural network processing to the first, second and third set of values. The artificial neural network processing includes artificial neural network training as a function of blood pressure signals to produce reconstructed blood pressure signals.
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公开(公告)号：US11696708B2
公开(公告)日：2023-07-11
申请号：US16824374
申请日：2020-03-19
IPC分类号： A61B5/1455 , A61B5/25 , A61B5/0245 , A61B5/00 , A61B5/291 , A61B5/026 , A61B5/268
CPC分类号： A61B5/14552 , A61B5/0245 , A61B5/0261 , A61B5/268 , A61B5/291 , A61B5/6803 , A61B5/6848
摘要： A probe device includes an optical device including at least one of a photodetector or a first light source. A cover structure is included and is arranged in front of the optical device. The cover structure includes an electrode which contacts, in use, a body tissue.
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公开(公告)号：US11684273B2
公开(公告)日：2023-06-27
申请号：US15976658
申请日：2018-05-10
CPC分类号： A61B5/02125 , A61B5/02141 , A61B5/02433 , A61B5/742 , G01J3/26 , G02F1/21 , A61B2562/0238 , G01J2001/442 , G01J2001/4466 , G01J2003/1226 , G02F1/213 , G02F2203/055 , G02F2203/11
摘要： In various embodiments, the present disclosure provides devices and systems for detecting the blood pressure of a user. In one embodiment, an optoelectronic device includes an array of avalanche photodiodes operating in Geiger mode. A tunable optical filter is optically coupled to the array and receives a light beam reflected from a vascularized tissue of the user, in response to the vascularized tissue being illuminated by an optical source.
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公开(公告)号：US11337617B2
公开(公告)日：2022-05-24
申请号：US16037328
申请日：2018-07-17
发明人： Francesco Rundo , Piero Fallica , Sabrina Conoci , Salvatore Petralia , Massimo Cataldo Mazzillo
摘要： In an embodiment, PhotoPlethysmoGraphy (PPG) signals are processed by detecting peaks and valleys in the PPG signal, segmenting the PPG signal to provide a time series of PPG waveforms located between two subsequent valleys in the PPG signal, applying to the waveforms in the time series pattern recognition with respect to a reference PPG waveform pattern produced based on a mathematical model of the PPG signal by assigning to the waveforms in the time series a recognition score. A resulting PPG signal is produced by retaining the waveforms in the time series having an assigned recognition score reaching a recognition threshold, and discarding the waveforms in the time series having an assigned recognition score failing to reach the recognition threshold.
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公开(公告)号：US11229404B2
公开(公告)日：2022-01-25
申请号：US16195114
申请日：2018-11-19
摘要： Blood pressure signals are reconstructed from PhotoPlethysmoGraphy (PPG) signals by: receiving PPG signals including systolic, diastolic and dicrotic phases; and determining first and second derivatives of the PPG signals and: a first set of values indicative of lengths of the signal paths of the PPG signal, the first derivative and the second derivative thereof in the systolic, diastolic and dicrotic phases; a second set of values indicative of relative durations of the PPG signal and the first and second derivatives thereof in the systolic, diastolic and dicrotic phases; and a third set of values indicative of the time separation of peaks and/or valleys in subsequent waveforms of the PPG signal. Reconstruction also includes applying artificial neural network processing to the first, second and third set of values. The artificial neural network processing includes artificial neural network training as a function of blood pressure signals to produce reconstructed blood pressure signals.
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公开(公告)号：US10987007B2
公开(公告)日：2021-04-27
申请号：US16167817
申请日：2018-10-23
发明人： Francesco Rundo , Sabrina Conoci , Piero Fallica
摘要： A method of processing electrophysiological signals includes: receiving, over a limited time duration, sample electrocardiography (ECG) signals indicative of heart pulsatile activity occurring with a variable heart rate, wherein receiving the sample ECG signals is discontinued at an expiry of the limited time duration; receiving photoplethysmography (PPG) signals indicative of the heart pulsatile activity; determining a correlation between the sample ECG signals and the PPG signals; determining reconstructed ECG signals from the PPG signals as a function of the correlation between the sample ECG signals and the PPG signals; and estimating a heart rate variability of the variable heart rate as a function of the reconstructed ECG signals.
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公开(公告)号：US10700220B2
公开(公告)日：2020-06-30
申请号：US16228483
申请日：2018-12-20
IPC分类号： H01L31/107 , H01L31/0216 , H01L27/146 , G01J1/44 , H01L27/144 , H01L31/02
摘要： An array of Geiger-mode avalanche photodiodes is formed in a die and includes: an internal dielectric structure, arranged on the die; and an external dielectric region arranged on the internal dielectric structure. The external dielectric region is formed by an external material that absorbs radiation having a wavelength that falls in a stop-band with low wavelength and transmits radiation having a wavelength that falls in a pass-band with high wavelength, at least part of the pass-band including wavelengths in the infrared. The internal dielectric structure is formed by one or more internal materials that substantially transmit radiation having a wavelength that falls in the stop-band and in the pass-band and have refractive indices that fall in an interval having an amplitude of 0.4. In the stop-band and in the pass-band the external dielectric region has a refractive index with the real part that falls in the above interval.
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9.发明申请公开(公告)号：US20190117096A1
公开(公告)日：2019-04-25
申请号：US16167817
申请日：2018-10-23
发明人： Francesco Rundo , Sabrina Conoci , Piero Fallica
摘要： A method of processing electrophysiological signals includes: receiving, over a limited time duration, sample electrocardiography (ECG) signals indicative of heart pulsatile activity occurring with a variable heart rate, wherein receiving the sample ECG signals is discontinued at an expiry of the limited time duration; receiving photoplethysmography (PPG) signals indicative of the heart pulsatile activity; determining a correlation between the sample ECG signals and the PPG signals; determining reconstructed ECG signals from the PPG signals as a function of the correlation between the sample ECG signals and the PPG signals; and estimating a heart rate variability of the variable heart rate as a function of the reconstructed ECG signals.
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公开(公告)号：US10205036B2
公开(公告)日：2019-02-12
申请号：US15868929
申请日：2018-01-11
IPC分类号： H01L31/107 , H01L31/0216 , G01J1/44 , H01L27/144 , H01L31/02 , H01L27/146
摘要： An array of Geiger-mode avalanche photodiodes is formed in a die and includes: an internal dielectric structure, arranged on the die; and an external dielectric region arranged on the internal dielectric structure. The external dielectric region is formed by an external material that absorbs radiation having a wavelength that falls in a stop-band with low wavelength and transmits radiation having a wavelength that falls in a pass-band with high wavelength, at least part of the pass-band including wavelengths in the infrared. The internal dielectric structure is formed by one or more internal materials that substantially transmit radiation having a wavelength that falls in the stop-band and in the pass-band and have refractive indices that fall in an interval having an amplitude of 0.4. In the stop-band and in the pass-band the external dielectric region has a refractive index with the real part that falls in the above interval.
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