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公开(公告)号：US11241379B2
公开(公告)日：2022-02-08
申请号：US15780793
申请日：2016-12-01
Applicant: SUN PHARMACEUTICAL INDUSTRIES LTD.
Inventor： Samarth Kumar , Milan Natvarbhai Thakkar , Kandarp Maheshkumar Dave
IPC: A61K9/00 , A61J1/10 , A61K31/554 , A61K47/10
Abstract: The present invention relates to a parenteral dosage form comprising a) a ready-to-infuse, stable aqueous solution comprising diltiazem or its pharmaceutically acceptable salt, pH adjusting agent to provide a pH in the range of 3 to 5 and ethanol, and b) an infusion container filled with said aqueous solution.
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公开(公告)号：US11058679B2
公开(公告)日：2021-07-13
申请号：US15748878
申请日：2016-08-01
Applicant: SUN PHARMACEUTICAL INDUSTRIES LTD.
Inventor： Subhas Balaram Bhowmick , Prashant Kane , Samarth Kumar , Ramaji Karshanbhai Varu , Nisarg Bipinchandra Mistry , Swapnil Ramesh Patil
IPC: A61K31/475 , A61K9/00 , C07D519/04 , A61K36/24 , A61J3/00 , A61J1/05 , A61J1/10 , A61K9/08 , A61P35/00
Abstract: The present invention relates to a dosage form comprising an aqueous solution of a vinca alkaloid drug or its pharmaceutically acceptable salt in a flexible infusion container, and a light protective secondary packaging containing the flexible infusion container, wherein the dosage form is ready-to-infuse and wherein the aqueous solution is stable at room temperature.
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公开(公告)号：US10206872B2
公开(公告)日：2019-02-19
申请号：US15185452
申请日：2016-06-17
Applicant: SUN PHARMACEUTICAL INDUSTRIES LTD.
Inventor： Samarth Kumar , Prashant Kane , Subhas Balaram Bhowmick , Milan Natvarbhai Thakkar , Kandarp Maheshkumar Dave
IPC: A61K31/4468 , A61K9/00 , A61K47/26 , A61K9/08
Abstract: A method of treating a patient in need of therapy with fentanyl or a salt thereof, the method comprising providing a ready-to-administer solution consisting essentially of fentanyl or a salt thereof as the sole active ingredient, a sugar or sugar alcohol and water for injection, the solution having a pH in the range of 3.5 to 7.5, and parenterally administering the solution to the patient.
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公开(公告)号：US09241948B2
公开(公告)日：2016-01-26
申请号：US13871438
申请日：2013-04-26
Applicant: SUN PHARMACEUTICAL INDUSTRIES LTD.
Inventor： Samarth Kumar , Prashant Kane , Alok B. Namdeo , Subhas B Bhowmick , Kirti Ganorkar
IPC: A61K31/7068 , A61K9/00 , A61K47/02
CPC classification number: A61K31/7068 , A61K9/0019 , A61K47/02
Abstract: A large volume infusion dosage form of gemcitabine, comprising a stable large volume solution of gemcitabine or its pharmaceutically acceptable salt in an aqueous vehicle filled in a large volume infusion container, wherein the solution is ready-to-be-infused.
Abstract translation: 吉西他滨的体积大体积输注剂型，其包含稳定的大体积的吉西他滨或其药学上可接受的盐的溶液，其填充在大体积的输注容器中，其中所述溶液即将被注入。
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公开(公告)号：US12138419B2
公开(公告)日：2024-11-12
申请号：US18057595
申请日：2022-11-21
Applicant: Sun Pharmaceutical Industries Ltd.
Inventor： Subhas Balaram Bhowmick , Prashant Kane , Samarth Kumar , Kirti Ganorkar
Abstract: A perfusion container for directly administering to patients a dose of an antineoplastic drug calculated according to a patient's parameter, wherein the first perfusion container comprises a solution of antineoplastic drug at a concentration and volume such that the amount of antineoplastic drug in the container is equal to the calculated dose for one patient but less than the calculated dose for a second patient, the calculated dose is provided to first patient within 5% variance by directly administering the full volume of the solution of antineoplastic drug from the first perfusion container, further the first perfusion container is accompanied by a second top-up perfusion container comprising a solution of antineoplastic drug at a concentration and volume such that the calculated dose is provided within 5% variance by directly administering the full volume of the solution of antineoplastic drug from the first perfusion container and the second top-up container to the second patient.
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公开(公告)号：US11554207B2
公开(公告)日：2023-01-17
申请号：US16075791
申请日：2017-02-09
Applicant: SUN PHARMACEUTICAL INDUSTRIES LTD.
Inventor： Subhas Balaram Bhowmick , Prashant Kane , Samarth Kumar , Kirti Ganorkar
Abstract: A perfusion container for directly administering to patients a dose of an antineoplastic drug calculated according to a patient's parameter, wherein the first perfusion container comprises a solution of antineoplastic drug at a concentration and volume such that the amount of antineoplastic drug in the container is equal to the calculated dose for one patient but less than the calculated dose for a second patient, the calculated dose is provided to first patient within 5% variance by directly administering the full volume of the solution of antineoplastic drug from the first perfusion container, further the first perfusion container is accompanied by a second top-up perfusion container comprising a solution of antineoplastic drug at a concentration and volume such that the calculated dose is provided within 5% variance by directly administering the full volume of the solution of antineoplastic drug from the first perfusion container and the second top-up container to the second patient.
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公开(公告)号：US20130288994A1
公开(公告)日：2013-10-31
申请号：US13871438
申请日：2013-04-26
Applicant: SUN PHARMACEUTICAL INDUSTRIES LTD.
Inventor： Samarth Kumar , Prashant Kane , Alok B. Namdeo , Subhas B. Bhowmick , Kirti Ganorkar
IPC: A61K31/7068
CPC classification number: A61K31/7068 , A61K9/0019 , A61K47/02
Abstract: A large volume infusion dosage form of gemcitabine, comprising a stable large volume solution of gemcitabine or its pharmaceutically acceptable salt in an aqueous vehicle filled in a large volume infusion container, wherein the solution is ready-to-be-infused.
Abstract translation: 吉西他滨的体积大体积输注剂型，其包含稳定的大体积的吉西他滨或其药学上可接受的盐的溶液，其填充在大体积的输注容器中，其中所述溶液即将被注入。
