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公开(公告)号：US20150210761A1
公开(公告)日：2015-07-30
申请号：US14606441
申请日：2015-01-27
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kyung Eun Kim , Yoon Sook Lee , Sang Yeul Han , Hyung-Chan Kim , Kwang Hoon Lee , Hyo Seon Lee , Seok Kyun Kim
CPC classification number: C07K16/22 , A61K2039/505 , C07K16/3046 , C07K2317/34 , C07K2317/76 , C07K2317/92 , G01N33/6872 , G01N2333/515 , G01N2500/04
Abstract: An Ang2 specific antibody, a method of preventing and/or treating a disease related to the activation and/or overproduction (overexpression) of Ang2 by administering the antibody to a subject, and a method of screening a candidate substance for diagnosing, preventing, or treating a disease related to activation or overproduction of Ang2.
Abstract translation: Ang2特异性抗体，通过向受试者施用抗体来预防和/或治疗与激动和/或过量产生（过表达）Ang2有关的疾病的方法，以及筛选候选物质的方法，用于诊断，预防或/ 治疗与Ang2的活化或过量产生相关的疾病。
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公开(公告)号：US10934350B2
公开(公告)日：2021-03-02
申请号：US16004622
申请日：2018-06-11
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seok Kyun Kim , Sunghyun Kim , Sang Yeul Han , Seung Hyun Lee , Su Jin Kim , Yong In Kim , Hyung-Chan Kim , Kwang Hoon Lee , Hyo Seon Lee
IPC: A61K39/395 , A61K39/00 , C07K16/22 , G01N33/68 , C07K14/705 , C07K14/515 , A61K38/00
Abstract: An anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes with a Tie2 receptor through Ang2, and methods of using the same.
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公开(公告)号：US09994632B2
公开(公告)日：2018-06-12
申请号：US14721591
申请日：2015-05-26
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seok Kyun Kim , Sunghyun Kim , Sang Yeul Han , Seung Hyun Lee , Su Jin Kim , Yong In Kim , Hyung-Chan Kim , Kwang Hoon Lee , Hyo Seon Lee
IPC: C07K16/00 , C07K16/28 , C07K16/22 , A61K39/395 , G01N33/68 , C07K14/705 , C07K14/515 , A61K39/00 , A61K38/00
CPC classification number: C07K16/22 , A61K38/00 , A61K39/3955 , A61K2039/505 , C07K14/515 , C07K14/705 , C07K2317/24 , C07K2317/567 , C07K2317/622 , C07K2317/74 , C07K2317/75 , C07K2317/76 , C07K2317/92 , G01N33/6887 , G01N33/6893 , G01N2333/515
Abstract: An anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes with a Tie2 receptor through Ang2, and methods of using the same.
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公开(公告)号：US09725513B2
公开(公告)日：2017-08-08
申请号：US14336812
申请日：2014-07-21
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kwang Hoon Lee , Hyung-Chan Kim , Sang Yeul Han , Seok Kyun Kim , Kyung Eun Kim
CPC classification number: C07K16/2863 , C07K14/71 , C07K2317/73 , C07K2317/92 , C07K2318/20 , C07K2319/30
Abstract: A fusion polypeptide capable of binding simultaneously to angiopoietin 2, VEGF-C and VEGF-D; or capable of binding simultaneously to VEGF-C and VEGF-D, and methods for the preparation and use thereof.
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公开(公告)号：US20150037343A1
公开(公告)日：2015-02-05
申请号：US14447242
申请日：2014-07-30
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seok Kyun KIM , Sang Yeul Han , Kwang Hoon Lee , Kyung Eun Kim , Chung Ho Kim , Yong In Kim , Hyung-Chan Kim , Yoon Sook Lee , Hyo Seon Lee
CPC classification number: C07K16/22 , A61K2039/505 , C07K2317/21 , C07K2317/34 , C07K2317/622 , C07K2317/76 , C07K2317/92 , G01N2500/04 , Y02A50/412
Abstract: An Ang2 specific antibody, a method of inhibiting angiogenesis or a method of treating a disease related to the activation and/or overproduction of Ang2 using the antibody, and a composition for diagnosing a disease related to the activation and/or overproduction of Ang2 including the antibody.
Abstract translation: Ang2特异性抗体，抑制血管生成的方法或使用该抗体治疗与Ang2的活化和/或过量产生有关的疾病的方法，以及用于诊断与Ang2的活化和/或过量产生有关的疾病的组合物，包括 抗体。
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Patent Agency Ranking
公开(公告)号：US09580497B2
公开(公告)日：2017-02-28
申请号：US14606441
申请日：2015-01-27
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kyung Eun Kim , Yoon Sook Lee , Sang Yeul Han , Hyung-Chan Kim , Kwang Hoon Lee , Hyo Seon Lee , Seok Kyun Kim
CPC classification number: C07K16/22 , A61K2039/505 , C07K16/3046 , C07K2317/34 , C07K2317/76 , C07K2317/92 , G01N33/6872 , G01N2333/515 , G01N2500/04
Abstract: An Ang2 specific antibody, a method of preventing and/or treating a disease related to the activation and/or overproduction (overexpression) of Ang2 by administering the antibody to a subject, and a method of screening a candidate substance for diagnosing, preventing, or treating a disease related to activation or overproduction of Ang2.
Abstract translation: Ang2特异性抗体，通过向受试者施用抗体来预防和/或治疗与激动和/或过量产生（过表达）Ang2有关的疾病的方法，以及筛选候选物质的方法，用于诊断，预防或/ 治疗与Ang2的活化或过量产生相关的疾病。
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公开(公告)号：US20150337033A1
公开(公告)日：2015-11-26
申请号：US14721591
申请日：2015-05-26
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seok Kyun Kim , Sunghyun Kim , Sang Yeul Han , Seung Hyun Lee , Su Jin Kim , Yong In Kim , Hyung-Chan Kim , Kwang Hoon Lee , Hyo Seon Lee
IPC: C07K16/22 , G01N33/68 , C07K14/705 , C07K14/515 , A61K39/395 , A61K38/18
CPC classification number: C07K16/22 , A61K38/00 , A61K39/3955 , A61K2039/505 , C07K14/515 , C07K14/705 , C07K2317/24 , C07K2317/567 , C07K2317/622 , C07K2317/74 , C07K2317/75 , C07K2317/76 , C07K2317/92 , G01N33/6887 , G01N33/6893 , G01N2333/515
Abstract: An anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes with a Tie2 receptor through Ang2, and methods of using the same.
Abstract translation: 通过Ang2特异性结合血管发生诱导因子促血管生成素-2（Ang2）和与Tie2受体复合的抗Ang2抗体或其抗原结合片段及其使用方法。
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公开(公告)号：US10246511B2
公开(公告)日：2019-04-02
申请号：US15667424
申请日：2017-08-02
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kwang Hoon Lee , Hyung-Chan Kim , Sang Yeul Han , Seok Kyun Kim , Kyung Eun Kim
Abstract: A fusion polypeptide capable of binding simultaneously to angiopoietin 2, VEGF-C and VEGF-D; or capable of binding simultaneously to VEGF-C and VEGF-D, and methods for the preparation and use thereof.
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公开(公告)号：US10047154B2
公开(公告)日：2018-08-14
申请号：US14447242
申请日：2014-07-30
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seok Kyun Kim , Sang Yeul Han , Kwang Hoon Lee , Kyung Eun Kim , Chung Ho Kim , Yong In Kim , Hyung-Chan Kim , Yoon Sook Lee , Hyo Seon Lee
IPC: A61K39/395 , A61K39/00 , C07K16/00 , C07K16/22
Abstract: An Ang2 specific antibody, a method of inhibiting angiogenesis or a method of treating a disease related to the activation and/or overproduction of Ang2 using the antibody, and a composition for diagnosing a disease related to the activation and/or overproduction of Ang2 including the antibody.
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10.发明授权Antibodies or antigen-binding fragments thereof specifically binding to VEGF-C and use thereof 有权与VEGF-C特异性结合的抗体或其抗原结合片段及其用途公开(公告)号：US09562093B2
公开(公告)日：2017-02-07
申请号：US14518502
申请日：2014-10-20
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seok Kyun Kim , Sang Yeul Han , Kwang Hoon Lee , Kyung Eun Kim
IPC: A61K39/395 , C07K16/18 , C07K16/22
CPC classification number: C07K16/22 , C07K2317/21 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: An antibody or antigen-binding fragment thereof that specifically binds to and inhibits VEGF-C and uses thereof in a method of inhibiting angiogenesis and a method of preventing, treating, and/or diagnosing a disease associated with activation and/or overexpression of VEGF-C, using the antibody, and a method of detecting the presence of VEGF-C in a sample.
Abstract translation: 特异性结合并抑制VEGF-C的抗体或其抗原结合片段及其在抑制血管生成的方法中的用途及其预防，治疗和/或诊断与VEGF-活化和/或过表达有关的疾病的方法， 使用抗体，以及检测样品中VEGF-C的存在的方法。
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