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公开(公告)号：US5705145A
公开(公告)日：1998-01-06
申请号：US697230
申请日：1996-08-21
IPC分类号： A61K8/00 , A61K8/33 , A61K8/35 , A61K8/36 , A61K8/365 , A61K8/49 , A61K8/97 , A61Q17/04 , A61Q19/04 , A61K7/42 , A61K7/02
CPC分类号： A61K8/35 , A61K8/4946 , A61Q19/04 , Y10S514/938
摘要： Disclosed are cosmetic compositions for providing an artificial tan to skin which comprise dihydroxyacetone and an azole in a cosmetically or pharmaceutically acceptable carrier. Also disclosed is a method for providing an artificial tan to skin which comprises applying dihydroxyacetone and an azole to the skin.
摘要翻译： 公开了用于在化妆品或药学上可接受的载体中提供包含二羟基丙酮和唑的人造棕褐色的化妆品组合物。 还公开了一种提供皮肤的人造棕褐色的方法，其包括向皮肤施用二羟基丙酮和唑。
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公开(公告)号：US06171605B2
公开(公告)日：2001-01-09
申请号：US09349913
申请日：1999-07-08
IPC分类号： A61K700
CPC分类号： A61Q19/04 , A61K8/35 , A61K8/37 , A61K8/988 , Y10S514/844
摘要： The present invention relates to self-tanning compositions comprising an effective amount of DHA in combination with an effective amount of propolis extract. The compositions provide self-tanning compositions which can produce a tan with enhanced coloration. The self-tan produced using the compositions of the present invention is more natural looking. In another embodiment of the present invention, the compositions comprise DHA combined with caffeic acid phenethyl ester.
摘要翻译： 本发明涉及包含有效量的DHA与有效量的蜂胶提取物组合的自鞣组合物。 该组合物提供可以产生具有增强着色的棕褐色的自晒黑组合物。 使用本发明的组合物生产的自晒黑更自然。 在本发明的另一个实施方案中，组合物包含与咖啡酸苯乙酯组合的DHA。
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公开(公告)号：US6139855A
公开(公告)日：2000-10-31
申请号：US243362
申请日：1999-02-01
申请人： Gheorghe Cioca , Joseph Gubernick , Andrew J. Bevacqua , Nicolae Vrabie , Daniel H. Maes , Kenneth D. Marenus , Edward Pelle , Neelam Muizzuddin , Vasile Ionita-Manzatu , Mirela Cristina Ionita-Manzatu
发明人： Gheorghe Cioca , Joseph Gubernick , Andrew J. Bevacqua , Nicolae Vrabie , Daniel H. Maes , Kenneth D. Marenus , Edward Pelle , Neelam Muizzuddin , Vasile Ionita-Manzatu , Mirela Cristina Ionita-Manzatu
IPC分类号： A61K8/19 , A61K8/00 , A61K8/02 , A61K8/06 , A61K8/46 , A61K33/00 , A61K45/00 , A61K47/02 , A61Q19/00 , C02F1/00 , C02F1/461 , A61K9/10
CPC分类号： C02F1/4618 , A61K33/00 , C02F1/005 , C02F2103/026 , Y10S514/937
摘要： The invention relates to composition having enhanced biological activity, the compositions comprising at least one structured water. In particular, the compositions contain a combination of I and S waters and a biologically active agent, in which the activity of the agent is increased relative to its activity in a non-structured water composition.
摘要翻译： 本发明涉及具有增强的生物活性的组合物，所述组合物包含至少一种结构化水。 特别地，组合物含有I和S水的组合和生物活性剂，其中药物的活性相对于其在非结构化水组合物中的活性而增加。
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公开(公告)号：US5610199A
公开(公告)日：1997-03-11
申请号：US365810
申请日：1994-12-29
IPC分类号： C07D319/12 , A61K8/00 , A61K8/02 , A61K8/29 , A61K8/31 , A61K8/33 , A61K8/34 , A61K8/36 , A61K8/365 , A61K8/37 , A61K8/40 , A61K8/49 , A61K8/60 , A61K8/92 , A61K8/97 , A61K8/98 , A61Q1/00 , A61Q1/02 , A61Q1/04 , A61Q1/06 , A61Q13/00 , A61Q17/04 , A61K31/075 , A61K7/42
CPC分类号： A61K8/042 , A61K8/02 , A61K8/0229 , A61K8/365 , A61K8/37 , A61K8/375 , A61K8/498 , A61Q1/02 , A61Q1/06 , A61Q13/00 , A61Q17/04 , A61K2800/28 , A61Q19/007 , A61Q19/08 , Y10S514/937 , Y10S514/938 , Y10S514/939
摘要： The present invention relates to solid lipophilic compositions suitable for topical application to human skin and to methods for preparing and using such compositions. The solid lipophilic compositions of the invention comprise dibenzyl monosorbitol acetal (DBMSA), lipophilic materials and one or more cosmetic materials.
摘要翻译： 本发明涉及适用于局部施用于人皮肤的固体亲脂性组合物以及制备和使用这些组合物的方法。 本发明的固体亲脂性组合物包含二苄基单异山梨醇缩醛（DBMSA），亲脂性材料和一种或多种化妆品材料。
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公开(公告)号：US5780517A
公开(公告)日：1998-07-14
申请号：US780287
申请日：1997-01-08
IPC分类号： C07D319/12 , A61K8/00 , A61K8/02 , A61K8/29 , A61K8/31 , A61K8/33 , A61K8/34 , A61K8/36 , A61K8/365 , A61K8/37 , A61K8/40 , A61K8/49 , A61K8/60 , A61K8/92 , A61K8/97 , A61K8/98 , A61Q1/00 , A61Q1/02 , A61Q1/04 , A61Q1/06 , A61Q13/00 , A61Q17/04 , A61K31/075 , A61K7/42
CPC分类号： A61K8/042 , A61K8/02 , A61K8/0229 , A61K8/365 , A61K8/37 , A61K8/375 , A61K8/498 , A61Q1/02 , A61Q1/06 , A61Q13/00 , A61Q17/04 , A61K2800/28 , A61Q19/007 , A61Q19/08 , Y10S514/937 , Y10S514/938 , Y10S514/939
摘要： The present invention relates to solid lipophilic compositions suitable for topical application to human skin and to methods for preparing and using such compositions. The solid lipophilic compositions of the invention comprise dibenzyl monosorbitol acetal (DBMSA), lipophilic materials and one or more cosmetic materials.
摘要翻译： 本发明涉及适用于局部施用于人皮肤的固体亲脂性组合物以及制备和使用这些组合物的方法。 本发明的固体亲脂性组合物包含二苄基单异山梨醇缩醛（DBMSA），亲脂性材料和一种或多种化妆品材料。
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公开(公告)号：US5750125A
公开(公告)日：1998-05-12
申请号：US666750
申请日：1996-06-19
IPC分类号： A61K8/60 , A61K8/00 , A61K8/02 , A61K8/29 , A61K8/31 , A61K8/33 , A61K8/34 , A61K8/36 , A61K8/365 , A61K8/368 , A61K8/37 , A61K8/41 , A61K8/42 , A61K8/49 , A61K8/89 , A61K8/891 , A61K8/97 , A61K8/98 , A61K31/00 , A61P17/00 , A61P29/00 , A61Q1/00 , A61Q1/04 , A61Q1/06 , A61Q13/00 , A61Q15/00 , A61Q17/04 , A61Q19/00 , A61K7/00 , A61K7/32 , A61K7/42
CPC分类号： A61K8/0229 , A61K8/365 , A61K8/37 , A61K8/49 , A61K8/498 , A61Q1/06 , A61Q13/00 , A61Q17/04 , Y10S424/05
摘要： The present invention relates to compositions that are stable, solid, and clear and suitable for topical application to human skin and to methods for preparing and using such compositions. The compositions of the invention comprise dibenzyl monosorbitol acetal (DBMSA) and a refractory material having a refractive index of between about 1.50 and about 1.65.
摘要翻译： 本发明涉及稳定，固体和透明并适合于局部施用于人皮肤的组合物，以及制备和使用这些组合物的方法。 本发明的组合物包含二苄基单异山梨醇缩醛（DBMSA）和折射率介于约1.50至约1.65之间的耐火材料。
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公开(公告)号：US5304334A
公开(公告)日：1994-04-19
申请号：US874933
申请日：1992-04-28
IPC分类号： A61K9/107 , A61K8/00 , A61K8/03 , A61K8/06 , A61K8/41 , A61K8/70 , A61K8/72 , A61K8/73 , A61K8/81 , A61K8/89 , A61K8/891 , A61K9/113 , A61K9/127 , A61Q19/00 , B01F17/52 , B01J13/00 , C08L83/04 , C09K19/36 , C09K19/54 , A61K31/78 , A61K31/785
CPC分类号： B01J13/00 , A61K8/066 , A61K8/70 , A61K9/113 , A61K9/1274 , A61Q19/00 , C09K2019/525 , Y10S514/847 , Y10S514/937 , Y10S514/944 , Y10S516/90 , Y10S516/902
摘要： The instant invention relates to methods of preparing and stabilizing complex multiphase compositions that include distinct phases of water, gel, liquid crystal or oil and perfluoropolyether dispersed in a continuous phase of a silicone fluid. In particular, the present invention relates to a method of preparing a stable multiphase composition comprising the steps of mixing an aqueous solution of a water-soluble polymeric emulsifier, a silicone-based emulsifier and an oleophobic, hydrophobic silicone fluid in amounts effective to form a stable water-in-silicone emulsion; mixing the water-in-silicone emulsion with a hydrophilic gel comprising a homogeneous mixture of water and a sufficient amount of at least one viscosity-enhancing, water-soluble polymer, the emulsion and gel being combined in amounts effective to form a dispersion in which the gel is dispersed in the emulsion; and adding to the dispersion an oil or a thermotropic liquid crystal and a perfluoropolyether in amounts effective to form a stable, multiphase composition comprising a continuous phase of silicone fluid and independent, polydisperse phases of water, gel, oil or liquid crystal and perfluoropolyether.
摘要翻译： 本发明涉及制备和稳定复合多相组合物的方法，所述组合物包括分散在有机硅流体的连续相中的水，凝胶，液晶或油的不同相和全氟聚醚。 特别地，本发明涉及一种制备稳定多相组合物的方法，包括以下步骤：将水溶性聚合乳化剂，硅氧烷基乳化剂和疏油疏水硅氧烷流体的水溶液混合，其量有效地形成 稳定的硅氧烷硅乳液; 将水包硅乳液与亲水性凝胶混合，其包含水和足够量的至少一种增稠粘度的水溶性聚合物的均匀混合物，所述乳液和凝胶以有效形成分散体的量组合，其中 凝胶分散在乳液中; 并且将有效形成稳定的多相组合物的油或热致液晶和全氟聚醚加入到该分散体中，所述多相组合物包含硅油流体的连续相和水，凝胶，油或液晶和全氟聚醚的独立的多分散相。
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公开(公告)号：US06231874B1
公开(公告)日：2001-05-15
申请号：US09042345
申请日：1998-03-13
IPC分类号： A61K600
CPC分类号： C02F1/005 , Y10S514/937 , Y10S514/938
摘要： The invention relates to a cosmetic or pharmaceutical composition containing a moisturizing effective amount of S water, as well as a method for enhancing the moisturization capacity of a skin care composition containing an aqueous component comprising incorporating S water as all or part of the aqueous component
摘要翻译： 本发明涉及含有保湿有效量的S水的化妆品或药物组合物，以及用于增强含有水性成分的护肤组合物的保湿能力的方法，包括将S水作为全部或部分水性成分
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公开(公告)号：US06239088B1
公开(公告)日：2001-05-29
申请号：US09273061
申请日：1999-03-19
申请人： Liliana George , Andrew J. Bevacqua , Daniela Toma , Saul Miklean
发明人： Liliana George , Andrew J. Bevacqua , Daniela Toma , Saul Miklean
IPC分类号： C11D166
摘要： The present invention relates to a cleansing composition based on the composition of lachrymal fluid. The cleansing composition comprises an ionic aqueous base containing one or more electrolytes, a basic protein or amino acid, and optionally, a mucomimetic compound and a lysozyme. The cleansing composition is gentle to both skin and eyes, and is highly effective in removing even transfer-resistant makeup.
摘要翻译： 本发明涉及一种基于泪液组成的清洁组合物。 清洁组合物包含含有一种或多种电解质，碱性蛋白质或氨基酸以及任选的模拟化合物和溶菌酶的离子水性碱。 清洁组合物对皮肤和眼睛均柔和，并且在除去均匀耐转移的化妆品方面非常有效。
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公开(公告)号：US20090156689A1
公开(公告)日：2009-06-18
申请号：US12369230
申请日：2009-02-11
申请人： George Cioca , Vasile Ionita-Manzatu , Liliana George , Paolo U. Giacomoni , Andrew J. Bevacqua , Harvey Gedeon , Charles Craig Tadlock , Donald F. Collins , Thomas Mammone , Daniel H. Maes , Christina G. Fthenakis
发明人： George Cioca , Vasile Ionita-Manzatu , Liliana George , Paolo U. Giacomoni , Andrew J. Bevacqua , Harvey Gedeon , Charles Craig Tadlock , Donald F. Collins , Thomas Mammone , Daniel H. Maes , Christina G. Fthenakis
CPC分类号： A61Q19/00 , A61K8/97 , A61K8/99 , A61K35/32 , A61K36/064 , A61K36/14 , A61K36/185 , A61K36/21 , A61K36/23 , A61K36/28 , A61K36/38 , A61K36/48 , A61K36/484 , A61K36/53 , A61K36/54 , A61K36/58 , A61K36/738 , A61K36/82 , A61K36/87 , A61K36/886 , A61K36/896 , A61K36/9068 , A61K38/39 , A61K2800/28 , A61K2800/85 , A61K2300/00
摘要： The present invention relates to a method of modulating a selected biological activity of a naturally occurring material having one or more biological activities in an extract of the naturally occurring material, the method comprising incubating the extract in a medium in the presence of an aerobically metabolizing microorganism, under suitable aerobic conditions, for a period of time sufficient to modulate the selected activity with respect to baseline activity of the unincubated extract. The invention also relates to the bioconverted material so prepared, and the use of same in cosmetic or pharmaceutical compositions.
摘要翻译： 本发明涉及在天然存在的材料的提取物中调节具有一种或多种生物活性的天然存在物质的选定生物活性的方法，所述方法包括在有氧代谢微生物存在下将培养基中的提取物 在合适的有氧条件下，足以调节相对于未温育的提取物的基线活性的选定活性的时间。 本发明还涉及如此制备的生物转化材料及其在化妆品或药物组合物中的用途。
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