Inhibitors of hepatitis C virus replication
    1.
    发明授权
    Inhibitors of hepatitis C virus replication 失效
    丙型肝炎病毒复制抑制剂

    公开(公告)号:US07781474B2

    公开(公告)日:2010-08-24

    申请号:US11773912

    申请日:2007-07-05

    IPC分类号: A61K31/40 C07D207/00

    摘要: The embodiments provide compounds of the general Formula I, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments provide compounds of the general Formula II, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments provide compounds of the general Formula III, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.

    摘要翻译: 实施方案提供了通式I的化合物,以及包含主题化合物的组合物,包括药物组合物。 实施方案提供了通式II的化合物,以及包含主题化合物的组合物,包括药物组合物。 实施方案提供了通式III的化合物,以及包含主题化合物的组合物,包括药物组合物。 实施方案还提供治疗方法,包括治疗丙型肝炎病毒感染的方法和治疗肝纤维化的方法,所述方法通常涉及向有需要的个体施用有效量的主题化合物或组合物。

    NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION
    7.
    发明申请
    NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION 失效
    HEPATITIS C VIRUS REPLICATION的新型抑制剂

    公开(公告)号:US20080019942A1

    公开(公告)日:2008-01-24

    申请号:US11773912

    申请日:2007-07-05

    摘要: The embodiments provide compounds of the general Formula I, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments provide compounds of the general Formula II, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments provide compounds of the general Formula III, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.

    摘要翻译: 实施方案提供了通式I的化合物,以及包含主题化合物的组合物,包括药物组合物。 实施方案提供了通式II的化合物,以及包含主题化合物的组合物,包括药物组合物。 实施方案提供了通式III的化合物,以及包含主题化合物的组合物,包括药物组合物。 实施方案还提供治疗方法,包括治疗丙型肝炎病毒感染的方法和治疗肝纤维化的方法,所述方法通常涉及向有需要的个体施用有效量的主题化合物或组合物。