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1.5-Substituted-4-[(substituted phenyl) amino]-2-pyridone derivatives 有权
标题翻译: 5-取代的-4 - [(取代的苯基)氨基] -2-吡啶酮衍生物公开(公告)号:US20050026964A1
公开(公告)日:2005-02-03
申请号:US10876100
申请日:2004-06-24
申请人: Shannon Black , Michael Kaufman , Daniel Ortwine , Mark Plummer , John Quin , Gordon Rewcastle , Aurash Shahripour , Julie Spicer , Christopher Whitehead
发明人: Shannon Black , Michael Kaufman , Daniel Ortwine , Mark Plummer , John Quin , Gordon Rewcastle , Aurash Shahripour , Julie Spicer , Christopher Whitehead
IPC分类号: A61P35/00 , C07D213/78 , C07D213/80 , C07D213/82 , C07D213/87 , C07D401/12 , C07D413/04 , A61K31/4439 , A61K31/44 , C07D213/72
CPC分类号: C07D213/78 , C07D213/80 , C07D213/82 , C07D213/87 , C07D401/12 , C07D413/04
摘要: The present invention relates to 5-substituted-4-(substituted)phenylamino-2-pyridone derivatives, pharmaceutical compositions and methods of use thereof.
摘要翻译: 本发明涉及5-取代-4-(取代的)苯基氨基-2-吡啶酮衍生物,药物组合物及其使用方法。
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2.
公开(公告)号:US20070179118A1
公开(公告)日:2007-08-02
申请号:US11734200
申请日:2007-04-11
申请人: Mark Barvian , Richard Booth , John Quin , Joseph Repine , Derek Sheehan , Peter Toogood , Scott Vanderwel , Hairong Zhou
发明人: Mark Barvian , Richard Booth , John Quin , Joseph Repine , Derek Sheehan , Peter Toogood , Scott Vanderwel , Hairong Zhou
IPC分类号: A61K31/675 , A61K31/519
CPC分类号: C07D471/04 , A61K31/519 , A61K31/675
摘要: The present invention provides substituted 2-aminopyridines useful in treating cell proliferative disorders. The novel compounds of the present invention are potent inhibitors of cyclin-dependent kinases 4 (cdk4).
摘要翻译: 本发明提供了可用于治疗细胞增殖性疾病的取代的2-氨基吡啶。 本发明的新化合物是细胞周期蛋白依赖性激酶4(cdk4)的有效抑制剂。
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3.
公开(公告)号:US20050137214A1
公开(公告)日:2005-06-23
申请号:US11046126
申请日:2005-01-28
申请人: Mark Barvian , Richard Booth , John Quin , Joseph Repine , Derek Sheehan , Peter Toogood , Scott Vanderwel , Hairong Zhou
发明人: Mark Barvian , Richard Booth , John Quin , Joseph Repine , Derek Sheehan , Peter Toogood , Scott Vanderwel , Hairong Zhou
IPC分类号: A61K31/519 , A61K31/5377 , A61K31/551 , A61K31/675 , A61P3/10 , A61P9/10 , A61P13/12 , A61P15/00 , A61P17/00 , A61P17/06 , A61P19/02 , A61P25/00 , A61P25/28 , A61P29/00 , A61P31/10 , A61P31/12 , A61P31/18 , A61P31/22 , A61P35/00 , A61P35/02 , A61P37/06 , A61P43/00 , C07D471/04 , C07F9/6561 , C07D487/02
CPC分类号: C07D471/04 , A61K31/519 , A61K31/675
摘要: The present invention provides substituted 2-aminopyridines useful in treating cell proliferative disorders. The novel compounds of the present invention are potent inhibitors of cyclin-dependent kinases 4 (cdk4).
摘要翻译: 本发明提供了可用于治疗细胞增殖性疾病的取代的2-氨基吡啶。 本发明的新化合物是细胞周期蛋白依赖性激酶4(cdk4)的有效抑制剂。
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