公开(公告)号：US4971956A

公开(公告)日：1990-11-20

申请号：US363307

申请日：1989-06-07

申请人： Shigeo Suzuki ,  Masuko Suzuki ,  Hitoshi Katayama

发明人： Shigeo Suzuki ,  Masuko Suzuki ,  Hitoshi Katayama

IPC分类号： A61K9/127

CPC分类号： A61K9/127

摘要： A new immunopotentiating agent is now provided, which is useful for enhancing the immune response in living animals, including man, against the bacterial and fungan infections and also against the growth of tumors, and which comprises as active ingredient a water-soluble chitin-oligomer selected from di-N-acetyl-chitobiose, tri-N-acetyl-chitotriose, tetra-N-acetyl-chitotetraose, penta-N-acetyl-chitopentaose, hexa-N-acetyl-chitohexaose and hepta-N-acetyl-chitoheptaose, or a water-soluble chitosan-oligomer selected from chitobiose, chitotriose, chitotetraose, chitopentaose, chitohexaose and chitoheptaose. An immunopotentiating method using said water-soluble chitin-oligomer or said water-soluble chitosan-oligomer as the active ingredient is also provided.

摘要翻译： 现在提供了一种新的免疫增强剂，其可用于增强包括人在内的活的动物中对细菌和功能感染的抗免疫反应，也可用于抗肿瘤生长，并且其包含作为活性成分的水溶性几丁质低聚物 选自二-N-乙酰基 - 壳寡糖，三-N-乙酰基 - 壳聚糖，四-N-乙酰基四聚四糖，五-N-乙酰基 - 五味子六羧酸，六-N-乙酰基二十六糖和七-N-乙酰基 - 或选自壳寡糖，壳聚糖，壳多糖，壳聚糖，壳二糖和曲米塔糖的水溶性壳聚糖低聚物。 还提供了使用所述水溶性几丁质低聚物或所述水溶性壳聚糖低聚物作为活性成分的免疫增强方法。