Liposome Preparation
    4.
    发明申请
    Liposome Preparation 审中-公开
    脂质体制备

    公开(公告)号:US20090169610A1

    公开(公告)日:2009-07-02

    申请号:US12223517

    申请日:2007-02-02

    IPC分类号: A61K9/127 A61K39/395

    摘要: The present invention provides cancer treatment preparations of excellent targetability. The sugar chain-modified liposomes of the present invention, which contain an aromatase inhibitor, anti-androgenic agent, lyase inhibitor, GnRH agonist, GnRH antagonist, anti-angiogenic agent, tyrosine kinase inhibitor, serine-threonine kinase inhibitor, antibody having an anticancer activity, ansamitocin, capecitabine, celmoleukin, docetaxel hydrate, gemcitabine hydrochloride, oxaliplatin, prednisolone, tegafur-uracil mixtures, zinostatin stimalamer or arsenic trioxide may be used as cancer treatment preparations having an excellent targetability.

    摘要翻译: 本发明提供了具有优异目标性的癌症治疗制剂。 含有芳香酶抑制剂,抗雄激素剂,裂解酶抑制剂,GnRH激动剂,GnRH拮抗剂,抗血管生成剂,酪氨酸激酶抑制剂,丝氨酸 - 苏氨酸激酶抑制剂,抗癌剂的本发明糖链修饰脂质体 活性,安曲霉素,卡培他滨,纤维白蛋白,多西紫杉醇水合物,盐酸吉西他滨,奥沙利铂,泼尼松龙,替加氟 - 尿嘧啶混合物,维生素D抑制素或三氧化二砷可用作具有优异靶向性的癌症治疗制剂。

    Novel gene and use thereof
    5.
    发明申请
    Novel gene and use thereof 失效
    新基因及其用途

    公开(公告)号:US20060183158A1

    公开(公告)日:2006-08-17

    申请号:US11353221

    申请日:2006-02-10

    CPC分类号: C07K14/47 A61K38/00

    摘要: A protein and DNA encoding the same are useful as preventives/remedies for diseases such as hypoglycemia, etc. The protein of the present invention is also useful as a reagent for screening a compound that inhibits the binding of the protein of the present invention to IRAP (insulin responsive aminopeptidase) or to GLUT4 (glucose transporter 4). The compound that inhibits the binding of the protein of the present invention to IRAP or GLUT4 is useful as a preventive/remedy for diseases, e.g., hyperglycemia, diabetes mellitus, etc.

    摘要翻译: 编码该蛋白质的蛋白质和DNA可用作诸如低血糖等疾病的预防剂/治疗剂。本发明的蛋白质也可用作筛选抑制本发明的蛋白质与IRAP结合的化合物的试剂 (胰岛素反应性氨基肽酶)或GLUT4(葡萄糖转运蛋白4)。 抑制本发明的蛋白质与IRAP或GLUT4结合的化合物可用作疾病例如高血糖症,糖尿病等的预防/治疗。

    Gene and use thereof
    6.
    发明授权
    Gene and use thereof 失效
    基因及其用途

    公开(公告)号:US07294475B2

    公开(公告)日:2007-11-13

    申请号:US11353221

    申请日:2006-02-10

    IPC分类号: G01N33/53 C07K14/00

    CPC分类号: C07K14/47 A61K38/00

    摘要: A protein and DNA encoding the same are useful as preventives/remedies for diseases such as hypoglycemia, etc. The protein of the present invention is also useful as a reagent for screening a compound that inhibits the binding of the protein of the present invention to IRAP (insulin responsive aminopeptidase) or to GLUT4 (glucose transporter 4). The compound that inhibits the binding of the protein of the present invention to IRAP or GLUT4 is useful as a preventive/remedy for diseases, e.g., hyperglycemia, diabetes mellitus, etc.

    摘要翻译: 编码该蛋白质的蛋白质和DNA可用作诸如低血糖等疾病的预防剂/治疗剂。本发明的蛋白质也可用作筛选抑制本发明的蛋白质与IRAP结合的化合物的试剂 (胰岛素反应性氨基肽酶)或GLUT4(葡萄糖转运蛋白4)。 抑制本发明的蛋白质与IRAP或GLUT4结合的化合物可用作疾病例如高血糖症,糖尿病等的预防/治疗。

    Gene and use thereof
    7.
    发明授权
    Gene and use thereof 失效
    基因及其用途

    公开(公告)号:US07064106B2

    公开(公告)日:2006-06-20

    申请号:US10168067

    申请日:2000-12-19

    CPC分类号: C07K14/47 A61K38/00

    摘要: A protein and DNA encoding the same are useful as preventives/remedies for diseases such as hypoglycemia, etc. The protein of the present invention is also useful as a reagent for screening a compound that inhibits the binding of the protein of the present invention to IRAP (insulin responsive aminopeptidase) or to GLUT4 (glucose transporter 4). The compound that inhibits the binding of the protein of the present invention to IRAP or GLUT4 is useful as a preventive/remedy for diseases, e.g., hyperglycemia, diabetes mellitus, etc.

    摘要翻译: 编码该蛋白质的蛋白质和DNA可用作诸如低血糖等疾病的预防剂/治疗剂。本发明的蛋白质也可用作筛选抑制本发明的蛋白质与IRAP结合的化合物的试剂 (胰岛素反应性氨基肽酶)或GLUT4(葡萄糖转运蛋白4)。 抑制本发明的蛋白质与IRAP或GLUT4结合的化合物可用作疾病例如高血糖症,糖尿病等的预防/治疗。