Method and device for detecting weak optical signals
    7.
    发明授权
    Method and device for detecting weak optical signals 有权
    用于检测弱光信号的方法和装置

    公开(公告)号:US08110788B2

    公开(公告)日:2012-02-07

    申请号:US12309046

    申请日:2007-07-04

    IPC分类号: H04N17/00

    摘要: An optical detection device is disclosed. The device comprises a photoelectric unit, configured to sense incoming photons and to produce electrical signals pertaining to at least a few of the photons within a plurality of temporally resolved time-windows; an analog-to-digital unit, configured to generate digital representation of the electrical signals; and a digital integrating unit, configured to integrate the digital representation over at least part of the temporally resolved time-windows to provide integrated data corresponding to the photons.

    摘要翻译: 公开了一种光学检测装置。 该装置包括光电单元,其被配置为感测入射光子并且产生与多个时间上分辨的时间窗内的至少几个光子有关的电信号; 一个模拟数字单元,被配置为产生电信号的数字表示; 以及数字积分单元,被配置为通过至少部分时间分辨的时间窗口来整合数字表示以提供对应于光子的集成数据。

    Methods of detecting cancer cells and use of same for diagnosing and monitoring treatment of the disease
    8.
    发明申请
    Methods of detecting cancer cells and use of same for diagnosing and monitoring treatment of the disease 失效
    检测癌细胞的方法及其用途,用于诊断和监测疾病的治疗

    公开(公告)号:US20090232740A1

    公开(公告)日:2009-09-17

    申请号:US12379974

    申请日:2009-03-05

    CPC分类号: G01N33/5011 C12Q1/42

    摘要: A method of detecting cancer cells is disclosed. The method comprises (a) contacting the cell with a substrate for an enzyme under conditions wherein the enzyme catalyzes a reaction of the cell with said substrate, so as to generate a product capable of producing an electrical signal; and (b) measuring a level of the electrical signal, wherein a difference in a level of said electrical signal compared to a predetermined threshold is indicative of a cancer cell. The method may be adapted for diagnosis, monitoring a cancer therapy, identifying agents capable of treating cancer and individually optimizing a cancer therapy.

    摘要翻译: 公开了一种检测癌细胞的方法。 该方法包括(a)在酶催化细胞与所述底物的反应的条件下,使细胞与酶底物接触,从而产生能产生电信号的产物; 和(b)测量电信号的电平,其中所述电信号的电平差与预定阈值相比指示癌细胞。 该方法可适用于诊断,监测癌症治疗,鉴定能够治疗癌症并单独优化癌症治疗的药剂。

    Electroless deposition of metal films with spray processor
    10.
    发明授权
    Electroless deposition of metal films with spray processor 失效
    用喷雾处理器无电沉积金属膜

    公开(公告)号:US6065424A

    公开(公告)日:2000-05-23

    申请号:US768447

    申请日:1996-12-18

    摘要: Electroless plating of very thin metal films, such as copper, is accomplished with a spray processor. Atomized droplets or a continuous stream of an electroless plating solution are sprayed on a substrate. The electroless plating solution may be prepared by mixing a reducing solution and a metal stock solution immediately prior to the spraying. The deposition process may be carried out in an apparatus which includes metal stock solution and reducing reservoirs, a mixing chamber for forming the plating solution, optionally an inert gas or air (oxygen) source, a process chamber in which the solution is sprayed on the substrate and a control system for providing solutions to the mixing chamber and the process chamber in accordance with a predetermined program for automated mixing and spraying of the plating solution. The process can be used to form metal films as thin as 100 .ANG. and these films have low resistivity values approaching bulk values, low surface roughness, excellent electrical and thickness uniformity and mirror-like surface. Low temperature annealing may be used to further improve electrical characteristics of the deposited films. The thin metal films produced by the disclosed process can be used in semiconductor wafer fabrication and assembly, and in preparation of thin film discs, thin film heads, optical storage devices, sensor devices, microelectromachined sensors (MEMS) and actuators, and optical filters.

    摘要翻译: 使用喷雾处理器实现非常薄的金属膜(例如铜)的无电镀。 将雾化的液滴或连续的无电镀液流喷射到基底上。 化学镀溶液可以通过在喷雾之前立即混合还原溶液和金属储备溶液来制备。 沉积过程可以在包括金属储备溶液和还原储存器的设备,用于形成电镀溶液的混合室,任选的惰性气体或空气(氧)源),其中溶液喷洒在其上的处理室 基板和用于根据用于电镀液的自动混合和喷涂的预定程序向混合室和处理室提供溶液的控制系统。 该方法可用于形成薄至100的金属膜,并且这些膜具有接近体积值,低表面粗糙度,优异的电和厚度均匀性以及镜面状表面的低电阻率值。 可以使用低温退火来进一步改善沉积膜的电特性。 通过所公开的方法制造的薄金属膜可用于半导体晶片制造和组装,以及薄膜盘,薄膜头,光学存储装置,传感器装置,微机电传感器(MEMS)和致动器以及光学滤波器的制备中。