利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

12 条记录 (耗时 0.026 秒)

    Biosensor
    1.
    发明授权
    Biosensor 有权
    生物传感器

    公开(公告)号：US08673127B2

    公开(公告)日：2014-03-18

    申请号：US12928841

    申请日：2010-12-21

    申请人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Masaki Fujiwara ,  Takahiro Nakaminami ,  Junko Nakayama ,  Eriko Yamanishi

    发明人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Masaki Fujiwara ,  Takahiro Nakaminami ,  Junko Nakayama ,  Eriko Yamanishi

    IPC分类号： G01N27/327

    CPC分类号： C12Q1/003

    摘要： In a biosensor for measuring a specific substance in a liquid sample, one or a combination of sugar alcohol, metallic salt, organic acid or organic acid salt which has at least one carboxyl group in a molecule, and organic acid or organic acid salt which has at least one carboxyl group and one amino group in a molecule, is included in a reagent layer provided on electrodes, thereby providing a highly-accurate biosensor which is excellent in stability and has high response (sensitivity, linearity) of the sensor to the substrate concentration.

    摘要翻译： 在用于测量液体样品中的特定物质的生物传感器中，分子中具有至少一个羧基的糖醇，金属盐，有机酸或有机酸盐的一种或组合，以及有机酸或有机酸盐，其具有 分子中的至少一个羧基和一个氨基被包含在设置在电极上的试剂层中，从而提供稳定性优异并且具有高传感器对基板的响应（灵敏度，线性）的高精度生物传感器 浓度。

    Biosensor
    2.
    发明申请
    Biosensor 审中-公开
    生物传感器

    公开(公告)号：US20100006432A1

    公开(公告)日：2010-01-14

    申请号：US12456199

    申请日：2009-06-12

    申请人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Masaki Fujiwara ,  Takahiro Nakaminami ,  Junko Nakayama ,  Eriko Yamanishi

    发明人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Masaki Fujiwara ,  Takahiro Nakaminami ,  Junko Nakayama ,  Eriko Yamanishi

    IPC分类号： G01N27/30 ,  G01N27/26

    CPC分类号： C12Q1/003

    摘要： In a biosensor for measuring a specific substance in a liquid sample, one or a combination of sugar alcohol, metallic salt, organic acid or organic acid salt which has at least one carboxyl group in a molecule, and organic acid or organic acid salt which has at least one carboxyl group and one amino group in a molecule, is included in a reagent layer provided on electrodes, thereby providing a highly-accurate biosensor which is excellent in stability and has high response (sensitivity, linearity) of the sensor to the substrate concentration.

    摘要翻译： 在用于测量液体样品中的特定物质的生物传感器中，分子中具有至少一个羧基的糖醇，金属盐，有机酸或有机酸盐的一种或组合，以及有机酸或有机酸盐，其具有 分子中的至少一个羧基和一个氨基被包含在设置在电极上的试剂层中，从而提供稳定性优异并且具有高传感器对基板的响应（灵敏度，线性）的高精度生物传感器 浓度。

    Biosensor
    3.
    发明授权
    Biosensor 有权
    生物传感器

    公开(公告)号：US06911131B2

    公开(公告)日：2005-06-28

    申请号：US09979842

    申请日：2001-03-28

    申请人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Masaki Fujiwara ,  Takahiro Nakaminami ,  Junko Nakayama ,  Eriko Yamanishi

    发明人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Masaki Fujiwara ,  Takahiro Nakaminami ,  Junko Nakayama ,  Eriko Yamanishi

    IPC分类号： C12Q1/00 ,  G01N27/327 ,  G01N21/00

    CPC分类号： C12Q1/003

    摘要： In a biosensor for measuring a specific substance in a liquid sample, one or a combination of sugar alcohol, metallic salt, organic acid or organic acid salt which has at least one carboxyl group in a molecule, and organic acid or organic acid salt which has at least one carboxyl group and one amino group in a molecule, is included in a reagent layer provided on electrodes, thereby providing a highly-accurate biosensor which is excellent in stability and has high response (sensitivity, linearity) of the sensor to the substrate concentration.

    摘要翻译： 在用于测量液体样品中的特定物质的生物传感器中，分子中具有至少一个羧基的糖醇，金属盐，有机酸或有机酸盐的一种或组合，以及有机酸或有机酸盐，其具有 分子中的至少一个羧基和一个氨基被包含在设置在电极上的试剂层中，从而提供稳定性优异并且具有高传感器对基板的响应（灵敏度，线性）的高精度生物传感器 浓度。

    Biosensor
    4.
    发明申请
    Biosensor 有权
    生物传感器

    公开(公告)号：US20110180404A1

    公开(公告)日：2011-07-28

    申请号：US12928841

    申请日：2010-12-21

    申请人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Masaki Fujiwara ,  Takahiro Nakaminami ,  Junko Nakayama ,  Eriko Yamanishi

    发明人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Masaki Fujiwara ,  Takahiro Nakaminami ,  Junko Nakayama ,  Eriko Yamanishi

    IPC分类号： G01N27/327

    CPC分类号： C12Q1/003

    摘要： In a biosensor for measuring a specific substance in a liquid sample, one or a combination of sugar alcohol, metallic salt, organic acid or organic acid salt which has at least one carboxyl group in a molecule, and organic acid or organic acid salt which has at least one carboxyl group and one amino group in a molecule, is included in a reagent layer provided on electrodes, thereby providing a highly-accurate biosensor which is excellent in stability and has high response (sensitivity, linearity) of the sensor to the substrate concentration.

    摘要翻译： 在用于测量液体样品中的特定物质的生物传感器中，分子中具有至少一个羧基的糖醇，金属盐，有机酸或有机酸盐的一种或组合，以及有机酸或有机酸盐，其具有 分子中的至少一个羧基和一个氨基被包含在设置在电极上的试剂层中，从而提供稳定性优异并且具有高传感器对基板的响应（灵敏度，线性）的高精度生物传感器 浓度。

    BIOSENSOR
    7.
    发明申请
    BIOSENSOR 审中-公开
    生物传感器

    公开(公告)号：US20090065356A1

    公开(公告)日：2009-03-12

    申请号：US12297676

    申请日：2007-04-19

    申请人： Junko Nakayama ,  Yoshifumi Takahara ,  Eriko Yamanishi ,  Yoshihiro Itoh

    发明人： Junko Nakayama ,  Yoshifumi Takahara ,  Eriko Yamanishi ,  Yoshihiro Itoh

    IPC分类号： G01N27/26

    CPC分类号： C12Q1/006

    摘要： In a biosensor for measuring glucose in a liquid sample, an additive agent which is one of an organic acid or organic acid salt having at least one carboxyl group in a molecule, an organic acid or organic acid salt having at least one amino group or carbonyl group in a molecule, a sugar alcohol, and a solubilized protein, or a combination thereof is added into a reagent layer including glucose dehydrogenase having flavin adenine dinucleotide as a coenzyme, which is provided on an insulating substrate. Thereby, the substrate specificity to glucose and the preservation stability can be enhanced, and further, reactions to sugars other than glucose can be avoided.

    摘要翻译： 在用于测量液体样品中的葡萄糖的生物传感器中，作为分子中具有至少一个羧基的有机酸或有机酸盐之一的添加剂，具有至少一个氨基的有机酸或有机酸盐或羰基 将分子中的一个基团，糖醇和增溶蛋白质或其组合加入到包含设置在绝缘基板上的作为辅酶的具有黄素腺嘌呤二核苷酸的葡萄糖脱氢酶的试剂层中。 因此，可以提高对葡萄糖的底物特异性和保存稳定性，进而可以避免对葡萄糖以外的糖的反应。

    BIOSENSOR
    8.
    发明申请
    BIOSENSOR 审中-公开
    生物传感器

    公开(公告)号：US20090134023A1

    公开(公告)日：2009-05-28

    申请号：US12297672

    申请日：2007-04-19

    申请人： Junko Nakayama ,  Yoshifumi Takahara ,  Eriko Yamanishi ,  Yoshihiro Itoh

    发明人： Junko Nakayama ,  Yoshifumi Takahara ,  Eriko Yamanishi ,  Yoshihiro Itoh

    IPC分类号： G01N27/26 ,  G01N33/487 ,  C12M1/00

    CPC分类号： C12Q1/006 ,  G01N33/5438

    摘要： In a biosensor of the present invention, BSA is contained in a reagent layer including a reagent which reacts specifically with glucose, and the glucose concentration in whole blood as a sample solution is electrochemically measured. When the sensor response characteristics when whole blood is used as the sample solution are measured, the influence by hematocrit to the sensor response characteristics is reduced according to the additive amount of BSA when the hematocrit value is in the range of 25% and below, while no BSA addition effect is recognized in the sensor response characteristics when the hematocrit value is in the range of 25 to 65%. Thereby, the influences by hematocrit and temperature can be reduced, and thus highly precise measurement can be performed.

    摘要翻译： 在本发明的生物传感器中，在包含与葡萄糖特异性反应的试剂的试剂层中含有BSA，作为样品溶液的全血中的葡萄糖浓度进行电化学测定。 当测量全血用作样品溶液时的传感器响应特性，当血细胞比容值在25％以下的范围内时，血细胞比容对传感器响应特性的影响根据BSA的添加量减少，而 当血细胞比容值在25至65％的范围内时，在传感器响应特性中不识别出BSA附加效应。 由此，可以降低血细胞比容和温度的影响，从而可以进行高精度的测量。

    Glucose sensor
    9.
    发明授权
    Glucose sensor 有权
    葡萄糖传感器

    公开(公告)号：US07005048B1

    公开(公告)日：2006-02-28

    申请号：US09807692

    申请日：2000-10-02

    申请人： Motokazu Watanabe ,  Keiko Yugawa ,  Toshihiko Yoshioka ,  Shiro Nankai ,  Junko Nakayama ,  Shoji Miyazaki ,  Hideyuki Baba

    发明人： Motokazu Watanabe ,  Keiko Yugawa ,  Toshihiko Yoshioka ,  Shiro Nankai ,  Junko Nakayama ,  Shoji Miyazaki ,  Hideyuki Baba

    IPC分类号： G01N27/327

    CPC分类号： C12Q1/006

    摘要： The present invention provides a high-performance glucose sensor having excellent storage stability and an improved response characteristic. This sensor comprises: an electrically insulating base plate; an electrode system including at least a working electrode and a counter electrode formed on the base plate; and a reaction layer containing at least pyrrolo-quinoline quinone dependent glucose dehydrogenase, formed in contact with or in the vicinity of the electrode system, and the reaction layer contains at least one kind of additive selected from the group consisting of gluconic acid and salts thereof.

    摘要翻译： 本发明提供一种具有优异的储存稳定性和改善的响应特性的高性能葡萄糖传感器。 该传感器包括：电绝缘基板; 电极系统，其至少包括形成在所述基板上的工作电极和对电极; 和至少含有与电极体系接触或附近形成的吡咯并喹啉醌依赖型葡萄糖脱氢酶的反应层，反应层含有选自葡萄糖酸及其盐的至少一种添加剂 。

    Cosmetic preparation
    10.
    发明申请
    Cosmetic preparation 审中-公开
    化妆品准备

    公开(公告)号：US20050214240A1

    公开(公告)日：2005-09-29

    申请号：US10508547

    申请日：2003-03-13

    申请人： Toshiyuki Ito ,  Takashi Isshiki ,  Junko Nakayama

    发明人： Toshiyuki Ito ,  Takashi Isshiki ,  Junko Nakayama

    IPC分类号： A61K8/55 ,  A61K8/67 ,  A61Q19/00 ,  A61Q19/08 ,  A61K7/075 ,  A61K7/08

    CPC分类号： A61Q19/08 ,  A61K8/553 ,  A61K8/671 ,  A61K2800/51 ,  A61K2800/522 ,  A61Q19/00

    摘要： A cosmetic preparation characterized by comprising (a) 0.01 to 10 wt % of a phospholipid, (b) 0.01 to 5 wt % of a nonionic surfactant having an HLB of 10 or higher and/or anionic surfactant, (c) 0.001 to 5 wt % of vitamin A or a derivative thereof, (d) 0.001 to 5 wt % of a stabilizer selected from among metal ion deactivators and antioxidants, and (g) water. The cosmetic preparation has satisfactory long-term stability, well spreads in application, gives excellent use feelings such as a fresh feeling and a nontacky feeling, and has high effects on the skin, such as a wrinkle diminishing effect.

    摘要翻译： 一种化妆品，其特征在于，包含（a）0.01〜10重量％的磷脂，（b）0.01〜5重量％的HLB为10以上的非离子表面活性剂和/或阴离子表面活性剂，（c）0.001〜5重量％ 维生素A或其衍生物的百分比，（d）0.001至5重量％的选自金属离子失活剂和抗氧化剂的稳定剂，和（g）水。 化妆品具有令人满意的长期稳定性，适用性良好，赋予了清新感和非棘手感等优异的使用感，对皮肤有较高的皱纹消除效果。