-
公开(公告)号:US09321771B2
公开(公告)日:2016-04-26
申请号:US14087179
申请日:2013-11-22
IPC分类号: A61K31/495 , C07D239/26 , C07D471/10 , C07D239/48 , C07D401/06 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D471/04 , C07D487/08
CPC分类号: A61K31/553 , A61K31/495 , A61K31/506 , A61K31/5355 , A61K31/5377 , A61K31/541 , A61K31/55 , A61K31/551 , C07D239/26 , C07D239/48 , C07D401/06 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D471/04 , C07D471/10 , C07D487/08
摘要: The present invention encompasses compounds of general formula (1) wherein R1 to R3 are defined as in claim 1, which are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation, and the use thereof for preparing a medicament having the above-mentioned properties.
摘要翻译: 本发明包括通式(1)的化合物,其中R 1至R 3如权利要求1中所定义,其适用于治疗以细胞增殖过度或异常为特征的疾病,以及其用于制备具有上述特征的药物的用途, 上述属性。
-
公开(公告)号:US08633183B2
公开(公告)日:2014-01-21
申请号:US13012082
申请日:2011-01-24
IPC分类号: C07D239/48 , A61K31/495
CPC分类号: A61K31/553 , A61K31/495 , A61K31/506 , A61K31/5355 , A61K31/5377 , A61K31/541 , A61K31/55 , A61K31/551 , C07D239/26 , C07D239/48 , C07D401/06 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D471/04 , C07D471/10 , C07D487/08
摘要: The present invention encompasses compounds of general formula (1) wherein R1 to R3 are defined as in claim 1, which are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation, and the use thereof for preparing a medicament having the above-mentioned properties.
摘要翻译: 本发明包括通式(1)的化合物,其中R 1至R 3如权利要求1中所定义,其适用于治疗以细胞增殖过度或异常为特征的疾病,以及其用于制备具有上述特征的药物的用途, 上述属性。
-
公开(公告)号:US08916548B2
公开(公告)日:2014-12-23
申请号:US13055949
申请日:2009-07-28
申请人: Tobias Wunberg , Ralph Brueckner , Dirk Kessler , Oliver Kraemer , Darryl McConnell , Siegfried Schneider , Lars van der Veen
发明人: Tobias Wunberg , Ralph Brueckner , Dirk Kessler , Oliver Kraemer , Darryl McConnell , Siegfried Schneider , Lars van der Veen
IPC分类号: C07D239/48 , C07D401/04 , C07D403/06
CPC分类号: C07D401/06 , C07D239/48 , C07D401/04 , C07D403/06 , C07D403/14 , C07D409/06 , C07D413/14
摘要: The present invention encompasses compounds of general Formula (1) wherein R1 to R4 are defined as in claim 1, which are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation, and the use thereof for preparing a medicament having the above-mentioned properties.
摘要翻译: 本发明包括通式(1)的化合物,其中R 1至R 4如权利要求1所定义,其适用于治疗以细胞增殖过度或异常为特征的疾病,以及其用于制备具有上述药物的药物的用途, 上述属性。
-
公开(公告)号:US08618111B2
公开(公告)日:2013-12-31
申请号:US13012081
申请日:2011-01-24
IPC分类号: A01N43/54 , C07D239/42 , C07D401/04
CPC分类号: C07D413/14 , C07D401/06 , C07D401/14 , C07D405/14 , C07D471/10 , C07D487/04 , C07D491/113 , C07D498/04
摘要: The present invention encompasses compounds of general formula (1) wherein R1 to R4R3 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a medicament having the above-mentioned properties.
摘要翻译: 本发明包括通式(1)的化合物,其中R 1至R 4 R 3如权利要求1中所定义,其适用于治疗以细胞增殖过度或异常为特征的疾病,以及其用于制备具有上述药物的药物的用途, 上述属性。
-
公开(公告)号:US20110281838A1
公开(公告)日:2011-11-17
申请号:US13055949
申请日:2009-07-28
申请人: Tobias Wunberg , Ralph Brueckner , Dirk Kessler , Oliver Kraemer , Darryl McConnell , Siegfried Schneider , Lars van der Veen
发明人: Tobias Wunberg , Ralph Brueckner , Dirk Kessler , Oliver Kraemer , Darryl McConnell , Siegfried Schneider , Lars van der Veen
IPC分类号: A61K31/506 , C07D401/06 , C07D471/04 , C07D403/06 , C07D405/14 , C07D409/14 , C07D401/14 , C07D413/14 , C07D417/14 , A61K31/505 , A61K31/5377 , A61K31/541 , A61P35/00 , A61P31/00 , A61P29/00 , A61P37/00 , C07D239/42
CPC分类号: C07D401/06 , C07D239/48 , C07D401/04 , C07D403/06 , C07D403/14 , C07D409/06 , C07D413/14
摘要: The present invention encompasses compounds of general Formula (1) wherein R1 to R4 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a medicament having the above-mentioned properties.
摘要翻译: 本发明包括通式(1)的化合物,其中R 1至R 4如权利要求1所定义,其适用于治疗以细胞增殖过度或异常为特征的疾病,以及其用于制备具有上述药物的药物的用途, 上述属性。
-
公开(公告)号:US20100210644A1
公开(公告)日:2010-08-19
申请号:US12665822
申请日:2008-06-24
IPC分类号: A61K31/5377 , C07D471/04 , A61K31/437 , C07D413/14 , C07D403/14 , A61K31/497 , A61P35/00 , A61P29/00 , A61P37/00 , A61P31/00
CPC分类号: C07D471/04
摘要: The present invention encompasses compounds of general formula (1) wherein the groups R1 to R5 are defined as in claim 1, which are suitable for treating diseases characterised by excessive or abnormal cell proliferation, and their use for preparing a medicament having the above-mentioned properties.
摘要翻译: 本发明包括通式(1)的化合物,其中R 1至R 5基团如权利要求1中所定义,其适用于治疗以细胞增殖过度或异常为特征的疾病,及其用于制备具有上述 属性。
-
公开(公告)号:US07893049B2
公开(公告)日:2011-02-22
申请号:US11696900
申请日:2007-04-05
申请人: Darryl McConnell , Bodo Betzemeier , Thomas Gerstberger , Maria Impagnatiello , Steffen Steurer , Lars van der Veen , Ulrike Weyer-Czernilofsky
发明人: Darryl McConnell , Bodo Betzemeier , Thomas Gerstberger , Maria Impagnatiello , Steffen Steurer , Lars van der Veen , Ulrike Weyer-Czernilofsky
IPC分类号: A61K31/00 , A61K31/44 , A61K31/445 , A61K31/497 , A61P43/00 , C07D211/32 , C07D217/00 , C07D279/10 , C07D401/00 , C07D413/00
CPC分类号: C07D513/04
摘要: The present invention encompasses compounds of general formula (1) wherein R1 to R6 are defined as in claim 1, which are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation, and the use thereof for preparing a medicament having the above-mentioned properties.
摘要翻译: 本发明包括通式(1)的化合物,其中R 1至R 6如权利要求1中所定义,其适用于治疗以细胞增殖过度或异常为特征的疾病,以及其用于制备具有上述药物的药物的用途, 上述属性。
-
公开(公告)号:US07902183B2
公开(公告)日:2011-03-08
申请号:US11696892
申请日:2007-04-05
申请人: Steffen Steurer , Bodo Betzemeier , Darryl McConnell , Thomas Gerstberger , Matthias Grauert , Matthias Hoffmann , Maria Impagnatiello , Lars van der Veen , Ulrike Weyer-Czernilofsky
发明人: Steffen Steurer , Bodo Betzemeier , Darryl McConnell , Thomas Gerstberger , Matthias Grauert , Matthias Hoffmann , Maria Impagnatiello , Lars van der Veen , Ulrike Weyer-Czernilofsky
IPC分类号: A61K31/43 , A61K31/497 , C07D513/04
CPC分类号: C07D513/04
摘要: The present invention encompasses compounds of general formula (1) wherein R1 to R5 are defined as in claim 1, which are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation, and the use thereof for preparing a medicament having the above-mentioned properties.
摘要翻译: 本发明包括通式(1)的化合物,其中R 1至R 5如权利要求1中所定义,其适用于治疗以细胞增殖过度或异常为特征的疾病,以及其用于制备具有上述药物的药物的用途, 上述属性。
-
-
-
-
-
-
-