-
公开(公告)号:US20210187068A1
公开(公告)日:2021-06-24
申请号:US16640039
申请日:2017-10-04
Applicant: Stellenbosch University , The University of Manchester
Inventor: Etheresia Pretorius , Douglas Bruce Kell
Abstract: A method for treating a subject suffering from Alzheimer's disease is provided. The method includes administering to the subject a therapeutically effective amount of lipopolysaccharide-binding protein (LBP). A composition including a therapeutically effective amount of LBP is also provided.
-
公开(公告)号:US11357822B2
公开(公告)日:2022-06-14
申请号:US16640039
申请日:2017-10-04
Applicant: Stellenbosch University
Inventor: Etheresia Pretorius , Douglas Bruce Kell
Abstract: A method for treating a subject suffering from Alzheimer's disease is provided. The method includes administering to the subject a therapeutically effective amount of lipopolysaccharide-binding protein (LBP). A composition including a therapeutically effective amount of LBP is also provided.
-
公开(公告)号:US20200300844A1
公开(公告)日:2020-09-24
申请号:US16763452
申请日:2018-11-13
Applicant: Stellenbosch University
Inventor: Etheresia Pretorius , Anna Martha Engelbrecht , Willem Jacobus Perold , Deon Pieter Neveling
IPC: G01N33/543 , G01N33/551
Abstract: A method, system, test strip, point-of-care device and computer-implemented method for detecting a level of inflammation in a subject is provided. The level of inflammation is detected by contacting a biological sample obtained from the subject with a serum amyloid A (SAA) capture agent. The capture agent is secured to a substrate and is configured to emit a signal upon binding to SAA. The signal is detected and a result indicating the level of inflammation in the subject is output.