利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

56 条记录 (耗时 0.074 秒)

    Microbial strains and process for the manufacture of biomaterials
    5.
    发明授权
    Microbial strains and process for the manufacture of biomaterials 有权
    微生物菌株和生物材料制造工艺

    公开(公告)号：US08748139B2

    公开(公告)日：2014-06-10

    申请号：US10607903

    申请日：2003-06-27

    申请人： Gjalt W. Huisman ,  Laura Z. Luo ,  Oliver P. Peoples

    发明人： Gjalt W. Huisman ,  Laura Z. Luo ,  Oliver P. Peoples

    IPC分类号： C12P7/52 ,  C12P21/06

    CPC分类号： C12N1/08 ,  C12N9/22 ,  C12P7/625

    摘要： DNA constructs and genetically engineered microbial strains constructed using these DNA constructs, which produce a nuclease enzyme with specificity for DNA and/or RNA, are provided. These strains secrete nuclease into the periplasm or growth medium in an amount effective to enhance productivity and/or recovery of polymer, and are particularly suited for use in high cell density fermentation processes. These constructs are useful for modifying microbial strains to improve production and recovery processes for polymers such as intracellular proteins, such as enzymes, growth factors, and cytokines; for producing polyhydroxyalkanoates; and for producing extracellular polysaccharides, such as xanthan gum, alginates, gellan gum, zooglan, hyaluronic acid and microbial cellulose.

    摘要翻译： 提供使用这些DNA构建体构建的DNA构建体和遗传工程化的微生物菌株，其产生对DNA和/或RNA具有特异性的核酸酶。 这些菌株以有效提高聚合物的生产力和/或回收率的量将核酸酶分泌到周质或生长培养基中，并且特别适用于高细胞密度发酵过程。 这些构建体可用于修饰微生物菌株以改善聚合物如细胞内蛋白质如酶，生长因子和细胞因子的生产和回收过程; 用于生产聚羟基链烷酸酯; 并且用于生产细胞外多糖，例如黄原胶，藻酸盐，结冷胶，动物胶，透明质酸和微生物纤维素。

    Microbial strains and processes for the manufacture of biomaterials
    6.
    发明授权
    Microbial strains and processes for the manufacture of biomaterials 有权
    用于制造生物材料的微生物菌株和方法

    公开(公告)号：US08728778B2

    公开(公告)日：2014-05-20

    申请号：US11924350

    申请日：2007-10-25

    申请人： Gjalt W. Huisman ,  Laura Z. Luo ,  Oliver P. Peoples

    发明人： Gjalt W. Huisman ,  Laura Z. Luo ,  Oliver P. Peoples

    IPC分类号： C12P7/52 ,  C12P21/06

    CPC分类号： C12N1/08 ,  C12N9/22 ,  C12P7/625

    摘要： DNA constructs and genetically engineered microbial strains constructed using these DNA constructs, which produce a nuclease enzyme with specificity for DNA and/or RNA, are provided. These strains secrete nuclease into the periplasm or growth medium in an amount effective to enhance productivity and/or recovery of polymer, and are particularly suited for use in high cell density fermentation processes. These constructs are useful for modifying microbial strains to improve production and recovery processes for polymers such as intracellular proteins, such as enzymes, growth factors, and cytokines; for producing polyhydroxyalkanoates; and for producing extracellular polysaccharides, such as xanthan gum, alginates, gellan gum, zooglan, hyaluronic acid and microbial cellulose.

    摘要翻译： 提供使用这些DNA构建体构建的DNA构建体和遗传工程化的微生物菌株，其产生对DNA和/或RNA具有特异性的核酸酶。 这些菌株以有效提高聚合物的生产力和/或回收率的量将核酸酶分泌到周质或生长培养基中，并且特别适用于高细胞密度发酵过程。 这些构建体可用于修饰微生物菌株以改善聚合物如细胞内蛋白质如酶，生长因子和细胞因子的生产和回收过程; 用于生产聚羟基链烷酸酯; 并且用于生产细胞外多糖，例如黄原胶，藻酸盐，结冷胶，动物胶，透明质酸和微生物纤维素。