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    Drug Coated Balloon Surface Relaxation Process To Minimize Drug Loss
    9.
    发明申请
    Drug Coated Balloon Surface Relaxation Process To Minimize Drug Loss 审中-公开
    药物涂层气球表面松弛过程，以尽量减少药物流失

    公开(公告)号：US20120064223A1

    公开(公告)日：2012-03-15

    申请号：US12882990

    申请日：2010-09-15

    申请人： Jose Gamez ,  John Stankus ,  Stephen D. Pacetti ,  Victoria M. Gong ,  Benjamyn Serna ,  Binh Nguyen

    发明人： Jose Gamez ,  John Stankus ,  Stephen D. Pacetti ,  Victoria M. Gong ,  Benjamyn Serna ,  Binh Nguyen

    IPC分类号： B05D5/00 ,  B05C13/02 ,  B05C11/00 ,  B05D3/00

    CPC分类号： A61M25/1029 ,  A61F2/958 ,  A61F2250/0067 ,  A61L29/16 ,  A61L2300/606 ,  A61L2420/02 ,  A61M2025/1031 ,  B05D2254/02

    摘要： Method of coating an expandable member is provided. The method comprises providing an expandable member having deflated and fully expanded configurations, and inflating the expandable member with a select amount of inflation medium, the select amount of inflation medium applied at a nominal pressure, disposing a therapeutic agent on at least a portion of the expandable member; and partially deflating the expandable member, wherein partially deflating includes releasing an initial amount of inflation medium from the expandable member such that the expandable member partially re-folds. The therapeutic agent can be dried on the expandable member, and a remaining amount of inflation medium can be withdrawn such that the expandable member resumes the completely folded configuration.

    摘要翻译： 提供涂覆可膨胀构件的方法。 该方法包括提供具有放气和完全展开构造的可膨胀构件，并且用选择量的充气介质充气可膨胀构件，以标称压力施加的选择量的充气介质，将治疗剂设置在至少一部分 可扩展成员; 并且部分地膨胀所述可膨胀构件，其中部分放气包括从所述可膨胀构件释放初始量的充气介质，使得所述可扩张构件部分地重新折叠。 治疗剂可以在可膨胀构件上干燥，并且可以取出剩余量的充气介质，使得可扩张构件恢复完全折叠的构型。

    TENSIONING PROCESS FOR COATING BALLOON
    10.
    发明申请
    TENSIONING PROCESS FOR COATING BALLOON 有权
    用于涂层气泡的拉伸过程

    公开(公告)号：US20120128863A1

    公开(公告)日：2012-05-24

    申请号：US13280067

    申请日：2011-10-24

    申请人： Binh T. Nguyen ,  Benjamyn Serna

    发明人： Binh T. Nguyen ,  Benjamyn Serna

    IPC分类号： B05D5/00 ,  B05D3/00 ,  B05C9/10 ,  B05C9/12 ,  B05D3/12 ,  B05D7/00

    CPC分类号： A61M25/1029 ,  A61F2002/9583 ,  A61F2250/0067 ,  A61M2025/1031 ,  A61M2025/105 ,  B05D3/12 ,  B05D7/02

    摘要： Method of coating an expandable member includes providing an expandable member having a proximal and a distal end with a guidewire lumen extending therebetween, the expandable member having a deflated and fully expanded configurations, and inflating the expandable member to an initial inflation pressure; positioning a mandrel within the guidewire lumen; tensioning the mandrel to straighten the guidewire lumen within the expandable member; and disposing a therapeutic agent on at least a portion of the expandable member. Method further includes partially deflating the expandable member to an intermediate pressure, and drying the therapeutic agent on the expandable member, and, if a folded expandable member is used, at least partially refolding the expandable member.

    摘要翻译： 涂覆可膨胀构件的方法包括提供具有近端和远端的可扩张构件，其中在其间延伸的导丝腔，所述可膨胀构件具有放气和完全膨胀的构造，并且将可膨胀构件充气至初始充气压力; 将心轴定位在导丝管腔内; 张紧心轴以拉直可扩张构件内的导丝腔; 以及在所述可扩张构件的至少一部分上设置治疗剂。 方法还包括将可膨胀构件部分地排气至中间压力，以及干燥可膨胀构件上的治疗剂，并且如果使用折叠的可膨胀构件，至少部分地重新折叠可膨胀构件。